503 research outputs found
Response to Letter to the Editor 'Adverse perinatal outcomes in the Australian Indigenous population, the role of asthma'
No full textLetter to the EditorAbstract unavailableVicki L. Clifton, Jui Das, Vicki Flenady, Kym Ra
Neonatal death is a major concern for Indigenous women with asthma during pregnancy and could be prevented with better models of care
No full textFirst published: 03 October 2021Asthma is the most common respiratory illness in Aboriginal and Torres Strait Islander Australians. From the Mater Mothers routinely collected perinatal data in Brisbane we have identified that 24% of Indigenous and 17% of non-Indigenous women have pregnancies complicated by asthma. Indigenous women with asthma are more likely to have poorer birth outcomes when compared to non-Indigenous women with asthma, with neonatal death being doubled in asthmatic Indigenous women. These data indicate that asthma management during pregnancy is an unmet need for Indigenous women and essential if we are to avoid these devastating outcomes for Indigenous families.Vicki L. Clifton, Jui Das, Vicki Flenady and Kym Ra
Spectatorship as a play on moral ambiguities: Neuro-evolutionary semiotic approach to lowly arousal emotions
No full textThis study seeks to outline a neuro-evolutionary semiotic model for our perception and interpretation of moral ambiguities in the wake of neuroaesthetics. This model is actually an integration of the Saussurean network of differences and the recently discovered default mode network: it serves on the one hand to rectify automatic responses generated by the mirror system in real-life situations, and on the other, to expand the applicability of the sign system for our appreciation of eerie or scary details found in the arts. Such a framework functions not only to blur binary oppositions set between high and lowly arousal emotions, but also to enhance our skills and confidence in dealing with uncertainties and oddities found in the arts. As opposed to experimental schemes devised in neuroaesthetics, which quantify our instant ratings of specific audial and visual inputs, the neuro-evolutionary model allows us some freedom and flexibility to re-evaluate our perceptions of motives concealed in characters’ behaviors. This study therefore enlarges on a qualitative approach to conceptualizing spectatorship in the world of art. We as intelligent and self-governing spectators should manage to align with odd characters’ positions so as to regain meaning, understanding, and harmony from our dealings. By way of comparing and contrasting two film characters’ dealings with valuable paintings and endearing families, the author argues for the fruitful functioning of the neuro-evolutionary sign system in revising our biases against seemingly immoral characters. It is observed that the sign system is characterized with the capacity of multiplying meaningful connections between characters’ motives, choices, and actions. It enables us to sort out and to appreciate strings of actions that enlarge on characters’ persistence and consistence of achieving certain goals. All in all, our choice of engaging with the daunting and the disconcerting fosters not only our pleasure and intelligence of viewing, but also the survival of odd characters in our community
Trajetórias para a leitura de uma história crítica das subjetividades na produção intelectual de Michel Foucault /
No full textTese (Doutorado) - Universidade de São Paulo, Faculdade de Filosofia, Letras e Ciências Humanas
for Inkjet Printing of Mg-Ion Asymmetric Micro-supercapacitors
No full textPage 7308, line 1 of the author list, Mr. Jui-Han Fu is incorrectly listed as the second author. He should instead be listed as having contributed equally to this work. This erratum does not affect any of the experimental results, discussions, or conclusions reported in the paper. The authors sincerely apologize for this unintended oversight. Steps have been taken to prevent similar problems from occurring in the future.published_or_final_versio
Integrated narrowband guided mode resonance photonic filters for advanced mid-infrared microspectroscopy
No full textCharacteristic molecular vibrational absorption wavelengths in mid-infrared (mid-IR) have been discovered for various applications, and as a result, a faster summary of an MIR spectrum can be gained by probing a set of discrete spectral fingerprints only, enabling many applications including fast early cancer diagnostics, real-time spectroscopic observation, on-chip chemical sensing, and simple/compact mid-IR instrumentation. In this ‘discrete-frequency infrared’ (DF-IR) spectroscopy approach, there is no Fourier transform infrared (FT-IR) interferometer that continuously scans a spectrum, and acquisition of spectral information can be made rapidly by combining an MIR detector and a tunable single-peak narrowband light source, such as selective thermal emitters, quantum cascade (QC) lasers, or a combination of a broadband incandescent globar and filters.
This thesis explores the DF-IR approach by using photonic filtering that is based on guided mode resonance (GMR). First, a useful analytical framework for optimal design of GMR devices is established based on a sound understanding of the underlying physics, and can be used to complement numerical electromagnetic simulations. Then, guided by this judicious design, the thesis presents experimental realization of high-performance GMR filters in the C-H stretching region (3-4 µm or 2500-3300 cm-1) of the mid-IR, and demonstrates GMR-filter-based DF-IR microspectroscopy for the first time. Last but not the least, this thesis introduces a new type of high-refractive-index photonic filter in the challenging but important molecular fingerprint mid-IR (6-10 µm or 1000-1600 cm-1) that shows behaviors distinct from conventional GMR. The combination of the high-index photonic devices and the recently developed QC emitters is proposed as a novel, promising solution to high-quality DF-IR microspectroscopy.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2017-05-01The student, Jui-Nung Liu, accepted the attached license on 2015-04-22 at 17:57.The student, Jui-Nung Liu, submitted this Dissertation for approval on 2015-04-22 at 18:17.This Dissertation was approved for publication on 2015-04-24 at 08:28.DSpace SAF Submission Ingestion Package generated from Vireo submission #8039 on 2015-07-22 at 14:26:20Made available in DSpace on 2015-07-22T22:45:59Z (GMT). No. of bitstreams: 2
LIU-DISSERTATION-2015.pdf: 4201423 bytes, checksum: fdcd9760f5fe4f9a5199fee4fba1a3fb (MD5)
LICENSE.txt: 4209 bytes, checksum: 4d613f9c6e3537afdc156bfd5b5c5e53 (MD5)
Previous issue date: 2015-04-24Embargo set by: Seth Robbins for item 80017
Lift date: 2017-07-22T22:46:21Z
Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemLimited Restriction Lifted for Item 80017 on 2017-07-23T09:15:35Z
Using whole exome sequencing to investigate the genetic bases of lysosomal storage diseases of unknown etiology
No full textLysosomes are membrane-bound, acidic eukaryotic cellular organelles that play important roles in the degradation of macromolecules. Mutations that cause the loss of lysosomal protein function can lead to a group of disorders categorized as the lysosomal storage diseases (LSDs). Suspicion of LSD is frequently based on clinical and pathologic findings, but in some cases, the underlying genetic and biochemical defects remain unknown. Here, we performed whole exome sequencing (WES) on 14 suspected LSD cases to evaluate the feasibility of using WES for identifying causal mutations. By examining 2,157 candidate genes potentially associated with lysosomal function, we identified eight variants in five genes as candidate disease-causing variants in four individuals. These included both known and novel mutations. Variants were corroborated by targeted sequencing and, when possible, functional assays. In addition, we identified nonsense mutations in two individuals in genes that are not known to have lysosomal function. However, mutations in these genes could have resulted in phenotypes that were diagnosed as LSDs. This study demonstrates that WES can be used to identify causal mutations in suspected LSD cases. We also demonstrate cases where a confounding clinical phenotype may potentially reflect more than one lysosomal protein defect.Peer reviewe
End-to-end thiocyanato-bridged helical chain polymer and dichlorido-bridged copper(II) complexes with a hydrazone ligand: synthesis, characterisation by electron paramagnetic resonance and variable- temperature magnetic studies, and inhibitory effects on human colorectal carcinoma cells
No full textThe reactions of the tridentate hydrazone ligand,N’-[1-(pyridin-2-yl)ethylidene]acetohydrazide (HL), obtained by condensation of 2-acetylpyridine with acetic hyadrazide, with copper nitrate trihydrate in the presence of thiocyanate, or with CuCl2produce two distinct coordination compounds, namely a one-dimensional
helical coordination chain of [CuL(NCS)]n(1) units, and a doubly chlorido-bridged dinuclear complex [Cu2L2Cl2] (2)
(where L=CH3C(O)=N − N=CCH3C5H4N). Single-crystal X-ray structural determination studies reveal that in complex1, a deprotonated hydrazone ligand L-coordinates a copper(II) ion that is bridged to two neighbouring metal centres by SCN-anions, generating a one-dimensional helical coordination chain. In complex2, two symmetry-related, adjacent copper(II) coordination entities are doubly chlorido-bridged, producing a dicopper entity with a Cu···Cu distance of 3.402 (1). The two coordination compounds have been fully characterised by elemental analysis, spectroscopic techniques including IR, UV– vis and electron paramagnetic resonance, and variable-temperature magnetic studies. The biological effects of1and2on the viability of human colorectal carcinoma cells (COLO-205
and HT-29) were evaluated using an MTT assay, and the results indicate that these complexes induce a decrease in cell-population growth of human colorectal carcinoma cells with apoptosis
Structural elucidation, EPR and magnetic interpretation of lanthanide (Ln = La, Nd, Sm) compounds with 4,4′-bipyridine and 2-sulfoterephthalate
No full textA series of three lanthanide compounds, namely, [La(stp)(bipy)(H2O)]·H2On(1), [Nd(stp)(bipy)(H2O)]·2H2On(2), and [Sm(stp)(bipy)(H2O)]·H2On(3) has been synthesized through the reaction of 2-sulfoterephthalic acid monosodium salt Na(H2stp), trivalent lanthanide nitrate [Ln(NO3)3·6H2O] and N-donor ancillary co-ligand, 4,4′-bipyridine (bipy). As a result of the potential coordination modes of the stp ligand and the bipy co-ligand, the aforementioned compounds are arranged in a 2-D network, as evidenced by single-crystal X-ray diffraction technique. In all the three compounds, the Ln ion presents a distorted tricapped trigonal-prismatic coordination geometry. The EPR measurements evidence a diamagnetic behaviour of compound 1 (La3+) whereas there exhibits a weak antiferromagnetic coupling between paramagnetic Ln3+ions (Nd3+and Sm3+) for compounds 2 and 3. This is also supported by the magnetic data obtained for compounds 1–3. The encapsulation of the lanthanide coordination polymers displays a moderate luminescent property
Adoption Right of Homosexual Couples
No full textBarriers encountered in adoption by homosexual couples and the potential policies changeSpring 2014Accompanied by video fil
- …
