43 research outputs found
The numerical solution of waveguide discontinuity problems
No full textA computational method for solving a wide range of transverse and longitudinal waveguide discontinuity problems is described. Results are obtained by the simultaneous solution of matrix equations, generated by Fourier analysis, which relate the complex amplitudes of orthogonal electric and magnetic field components. In some cases the solution is found to be sensitive to the way in
which infinite series of field functions are truncated, and it is shown how the optimum form of truncation can be determined for many configurations of practical importance.
Several examples showing the application of the method are
given, and comparison of results with those obtained by experiment, and by other analytical techniques, confirms its accuracy.
The application of the method in the design of discontinuities for higher-mode generation in multimode antennas is considered, particularly in connection with a multimode monopulse feed for a satellite-communication reflector antenna. Primary and secondary characteristics are determined theoretically for various modeconverter
configurations, allowing those giving satisfactory allround
performance to be selected. Comparison with conventional
feeds shows the multimode feed to be superior in many respects. A prototype multimode feed is constructed, and theoretical primary radiation patterns are compared with those obtained experimentally
Correction: Sankaranarayanan et al. Auger Emitter Conjugated PARP Inhibitor for Therapy in Triple Negative Breast Cancers: A Comparative In-Vitro Study. Cancers 2022, 14, 230
No full textThe authors wish to replace the ‘Author Contributions’ statement and the affiliation for Jochen Maurer of this article [1] with the following version since a wrong version was uploaded due to oversight: Author Contributions: A.M. and F.M. supervised and administered the project. R.A.S., A.M. and F.M. contributed to the study conception and design. R.A.S. and J.P. analyzed and curated the data. A.T.J.V., A.C., S.T. and C.B. conducted chemical syntheses. R.A.S. and J.P. carried out the cell culture, experiments with cell lines, western blot experiments, microscopy and imaging. R.A.S. and M.B. performed statistical analyses. A.T.J.V., C.B., S.T., A.C. and J.M. provided material and resources. R.A.S., J.P., M.B., A.M. and F.M. interpreted the analyzed data. R.A.S. wrote the manuscript. A.M., M.B., F.M. and J.M. corrected the manuscript. All authors have read and agreed to the published version of the manuscript. Affiliation 5: Department of Gynecology and Obstetrics, University Hospital Aachen, RWTH Aachen University, 52074 Aachen, Germany. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original article has been updated.</p
4D Trajectory De-Confliction For Future ATM By Applying Constraints
No full textIn the present ATC system conflicts between aircraft are detected and resolved in a stated-based approach. To meet traffic demand predictions, the global air traffic management (ATM) system needs revolutionary changes. Several visions on future ATM operations exist (e.g. NextGen, SESAR). A common function between the different visions is 4D Trajectory management. This function enables trajectory-based operation as opposed to the state-based approach of the present system. Instead of monitoring the current traffic situation and resolving short term conflicts by vectoring, the 4D trajectory management function de-conflicts all trajectories prior to execution. A key function of 4D trajectory management is the resolution of 4D trajectories. Conflict resolution of 4D trajectories is applied to conflict scenarios using constraints. A characteristic of a constraint is that it does not limit the aircraft to a particular solution but provides the aircraft the room to generate a trajectory within the actual solution space. Conflicting trajectories are resolved using constraints where the constraints provides an approximation of the solution space. This concept of trajectory de-confliction through the use of constraints is the topic of this thesis work.TelecommunicationsElectrical Engineering, Mathematics and Computer Scienc
OGLE-2012-BLG-0563Lb : a Saturn-mass planet around an M dwarf with the mass constrained by Subaru AO imaging
No full textA.F. was supported by the Astrobiology Project of the Center for Novel Science Initiatives (CNSI), National Institutes of Natural Sciences (NINS; Grant Number AB261005). T.S. acknowledges the financial support from the JSPS, JSPS23103002, JSPS24253004, and JSPS26247023. The MOA project is supported by grants JSPS25103508 and 23340064. NJR is a Royal Society of New Zealand Rutherford Discovery Fellow. Work by C.H. was supported by Creative Research Initiative Program (2009-0081561) of National Research Foundation of Korea. S.D. is supported by "the Strategic Priority Research Program—The Emergence of Cosmological Structures" of the Chinese Academy of Sciences (grant No. 09000000). The OGLE project has received funding from the National Science Centre, Poland, grant MAESTRO 2014/14/A/ST9/00121 to A.U. C.S. received funding from the European Union Seventh Framework Programme (FP7/2007–2013) under grant agreement No. 268421. K.A., D.M.B., M.D., K.H., M.H., C.L., C.S., R.A.S., and Y.T. would like to thank the Qatar Foundation for support from QNRF grant NPRP-09-476-1-078.We report the discovery of a microlensing exoplanet OGLE-2012-BLG-0563Lb with the planet–star mass ratio of ∼1 x 10-3. Intensive photometric observations of a high-magnification microlensing event allow us to detect a clear signal of the planet. Although no parallax signal is detected in the light curve, we instead succeed at detecting the flux from the host star in high-resolution JHK'-band images obtained by the Subaru/AO188 and Infrared Camera and Spectrograph instruments, allowing us to constrain the absolute physical parameters of the planetary system. With the help of spectroscopic information about the source star obtained during the high-magnification state by Bensby et al., we find that the lens system is located at 1.3-0.8+0.6 kpc from us, and consists of an M dwarf (0.34+0.12-0.20MΘ) orbited by a Saturn-mass planet (0.39-0.23+0.14 MJup) at the projected separation of 0.74-0.42+0.26 AU (close model) or 4.3-2.5+1.5 AU (wide model). The probability of contamination in the host star's flux, which would reduce the masses by a factor of up to three, is estimated to be 17%. This possibility can be tested by future high-resolution imaging. We also estimate the (J-Ks) and (H-Ks) colors of the host star, which are marginally consistent with a low metallicity mid-to-early M dwarf, although further observations are required for the metallicity to be conclusive. This is the fifth sub-Jupiter-mass (0.2 < mp/MJup < 1) microlensing planet around an M dwarf with the mass well constrained. The relatively rich harvest of sub-Jupiters around M dwarfs is contrasted with a possible paucity of ~1–2 Jupiter-mass planets around the same type of star, which can be explained by the planetary formation process in the core-accretion scheme.Peer reviewe
Análise das condições de trabalho em um incubatório de aves: o caso do setor de sexagem
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção.O trabalho proposto tem como objetivo principal melhorar as condições de trabalho daqueles que executam suas tarefas em incubatórios de ovos, mais especificamente, na sexagem dos pintos. Tal tarefa tem características de repetitividade, monotonia, num ambiente com temperaturas controladas, certo grau de partículas em suspensão, além de terem de manter perfeita higiene do corpo, do maquinário e da matéria-prima como condição sine qua non para o funcionamento do setor.. Para tanto, este estudo terá como ferramenta principal a Análise Ergonômica do Posto de Trabalho, a qual analisa, de um modo aprofundado e bastante abrangente, os fatores que interferem no desenvolvimento da tarefa. Entre estes, pode-se destacar a análise física do ambiente, onde temperatura, nível de pressão sonora, iluminação e velocidade das correntes de ar, entre outros, são analisados quantitativamente, sendo comparados com os valores indicados pela legislação vigente e apropriada. Além destes, as medidas antropométricas realizadas elevam o nível de informações necessárias para a identificação mais efetiva das pessoas que fizeram parte do estudo. Com o auxílio do Método de RULA e OWAS, são analisadas as posturas, sendo tais informações utilizadas para entender os posicionamentos e principais movimentos que podem vir a causar desconforto e dores. O trabalho procura reunir, numa análise ergonômica, outras informações importantes, visando subsidiar um redimensionamento do mobiliário, novas técnicas, movimentos e posturas que reduzam as causas mais deletérias na execução da tarefa
MOA-2011-BLG-262Lb : a sub-earth-mass moon orbiting a gas giant primary or a high velocity planetary system in the galactic bulge
No full textD.P.B. was supported by grants NASA-NNX12AF54G, JPL-RSA 1453175 and NSF AST-1211875. This MOA project is supported by the grants JSPS18253002 and JSPS20340052. T.S. acknowledges the financial support from the JSPS, JSPS23340044, JSPS24253004. This work was partially supported by a NASA Keck PI Data Award, administered by the NASA Exoplanet Science Institute. The Observatory was made possible by the generous financial support of the W. M. Keck Foundation. B.S.G. and A.G. were supported by NSF grant AST 110347. B.S.G., A.G., R.P.G. were supported by NASA grant NNX12AB99G. S.D. was partly supported through a Ralph E. and Doris M. Hansmann Membership at the IAS and by NSF grant AST-0807444. Work by J.C.Y. was performed in part under contract with the California Institute of Technology (Caltech) funded by NASA through the Sagan Fellowship Program. The OGLE project has received funding from the European Research Council under the European Community's Seventh Framework Programme (FP7/2007-2013)/ERC grant agreement No. 246678 to A.U. D.H. was supported by Czech Science Foundation grant GACR P209/10/1318. D.M.B., M.D., K.H., C.S., R.A.S., M.H. and Y.T. are supported by NPRP grant NPRP-09-476-1-78 from the Qatar National Research Fund (a member of the Qatar Foundation).We present the first microlensing candidate for a free-floating exoplanet-exomoon system, MOA-2011-BLG-262, with a primary lens mass of M host ~ 4 Jupiter masses hosting a sub-Earth mass moon. The argument for an exomoon hinges on the system being relatively close to the Sun. The data constrain the product MLπrel where ML is the lens system mass and πrel is the lens-source relative parallax. If the lens system is nearby (large πrel), then ML is small (a few Jupiter masses) and the companion is a sub-Earth-mass exomoon. The best-fit solution has a large lens-source relative proper motion, μrel = 19.6 ± 1.6 mas yr–1, which would rule out a distant lens system unless the source star has an unusually high proper motion. However, data from the OGLE collaboration nearly rule out a high source proper motion, so the exoplanet+exomoon model is the favored interpretation for the best fit model. However, there is an alternate solution that has a lower proper motion and fits the data almost as well. This solution is compatible with a distant (so stellar) host. A Bayesian analysis does not favor the exoplanet+exomoon interpretation, so Occam's razor favors a lens system in the bulge with host and companion masses of M host = 0.12 +0.19-0.06 MΘ and mcomp = 18+28-10M⊕, at a projected separation of a⊥ = 0.84+0.25−0.14 AU. The existence of this degeneracy is an unlucky accident, so current microlensing experiments are in principle sensitive to exomoons. In some circumstances, it will be possible to definitively establish the mass of such lens systems through the microlensing parallax effect. Future experiments will be sensitive to less extreme exomoons.Peer reviewe
Differential effects of angiotensin II and angiotensin-(1-7) at the nucleus tractus solitarii of transgenic rats with low brain angiotensinogen
No full textObjectives : In this study, we investigated the effects of angiotensin II and angiotensin-(1–7) at the nucleus tractus solitarii (nTS) in transgenic rats with a severe deficit in brain angiotensinogen production, TGR(ASrAOGEN) (TGR). Methods : Angiotensin II (10 pmol), angiotensin-(1–7) (10 pmol) or NaCl (0.9%/50 nl) were microinjected into the nTS of urethane-anaesthetized TGR (n = 36) and Sprague Dawley (SD) (n = 34) rats. Mean arterial pressure (MAP) and heart rate were measured via a femoral artery catheter and the baroreflex control of heart rate was evaluated after increases in MAP induced by phenylephrine (baroreflex bradycardia). Results : Angiotensin II microinjections into the nTS of the TGR induced a higher decrease in MAP and heart rate (−37 ± 5 mmHg and −69 ± 12 b.p.m., respectively) in comparison to SD rats (−18 ± 1 mmHg and −43 ± 5 b.p.m., respectively). In contrast, changes after angiotensin-(1–7) microinjections into the nTS of TGR (−6 ± 1 mmHg and −13 ± 4 b.p.m.) were significantly smaller than that induced in SD (−11 ± 2 mmHg and −24 ± 6 b.p.m.). The baseline baroreflex sensitivity to phenylephrine of TGR was accentuated in comparison to SD rats (0.70 ± 0.06 versus 0.44 ± 0.03 ms/mmHg). Angiotensin II microinjection into the nTS produced similar attenuation in the baroreflex bradycardia in both SD (0.28 ± 0.07 versus 0.5 ± 0.07 ms/mmHg, before injection) and TGR (0.44 ± 0.1 versus 0.82 ± 0.1 ms/mmHg, before injection). In contrast, angiotensin-(1–7) microinjection elicited a facilitation of the baroreflex bradycardia in SD (0.68 ± 0.12 versus 0.41 ± 0.03 ms/mmHg, before injection), while in TGR, angiotensin-(1–7) induced an attenuation of baroreflex bradycardia (0.34 ± 0.07 ms/mmHg versus 0.55 ± 0.05 ms/mmHg, before injection). Conclusions : These results indicate that a permanent inhibition of angiotensinogen synthesis in the brain can lead to an increase in the sensitivity of the baroreflex control of heart rate (baroreflex bradycardia) and an increase in angiotensin II responsiveness at the nTS. However, the nTS effect of angiotensin-(1–7) was significantly attenuated in these transgenic rats. These data further indicate that the decrease in brain angiotensins in the transgenic rats may be functionally relevant and support the concept of differential regulatory mechanisms for the effects of the two angiotensin peptides
Candidate gravitational microlensing events for future direct lens imaging
No full textThis material is based upon work supported by the National Science Foundation (NSF) Graduate Research Fellowship Program under grant No. DGE-0822215, awarded to C.B.H., and an international travel allowance through the Graduate Research Opportunities Worldwide, also awarded to C.B.H. and taken to Cheongju, Korea. T.S. is supported by the grant JSPS23340044 and JSPS24253004. The OGLE project has received funding from the European Research Council under the European Community's Seventh Framework Programme (FP7/2007-2013)/ERC grant agreement No. 246678 to A.U. Work by C.H. was supported by the Creative Research Initiative Program (2009-0081561) of the National Research Foundation of Korea. A.G. and B.S.G. acknowledge support from NSF AST-1103471 and from NASA grant NNX12AB99G. S.D. is supported by "The Strategic Priority Research Program—The Emergence of Cosmological Structures" of the Chinese Academy of Sciences (Grant No. XDB09000000). Work by J.C.Y. was performed in part under contract with the California Institute of Technology (Caltech) funded by NASA through the Sagan Fellowship Program. M.D., K.H., M.H., C.S., R.A.S., and Y.T. acknowledge grant NPRP-09-476-1-78 from the Qatar National Research Fund (a member of the Qatar Foundation). This publication was made possible by NPRP grant #X-019-1-006 from the Qatar National Research Fund (a member of the Qatar Foundation).The mass of the lenses giving rise to Galactic microlensing events can be constrained by measuring the relative lens-source proper motion and lens flux. The flux of the lens can be separated from that of the source, companions to the source, and unrelated nearby stars with high-resolution images taken when the lens and source are spatially resolved. For typical ground-based adaptive optics (AO) or space-based observations, this requires either inordinately long time baselines or high relative proper motions. We provide a list of microlensing events toward the Galactic bulge with high relative lens-source proper motion that are therefore good candidates for constraining the lens mass with future high-resolution imaging. We investigate all events from 2004 to 2013 that display detectable finite-source effects, a feature that allows us to measure the proper motion. In total, we present 20 events with μ ≥ 8 mas yr–1. Of these, 14 were culled from previous analyses while 6 are new, including OGLE-2004-BLG-368, MOA-2005-BLG-36, OGLE-2012-BLG-0211, OGLE-2012-BLG-0456, MOA-2012-BLG-532, and MOA-2013-BLG-029. In ≤12 yr from the time of each event the lens and source of each event will be sufficiently separated for ground-based telescopes with AO systems or space telescopes to resolve each component and further characterize the lens system. Furthermore, for the most recent events, comparison of the lens flux estimates from images taken immediately to those estimated from images taken when the lens and source are resolved can be used to empirically check the robustness of the single-epoch method currently being used to estimate lens masses for many events.Peer reviewe
Produção e caracterização de espuma cerâmica obtida a partir de lodo de anodização de alumínio
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Ciência e Engenharia de Materiais, Florianópolis, 2010As indústrias de produção e de transformação de materiais geram resíduos que nem sempre têm um fim ecologicamente adequado. Em muitos casos, entretanto, estes produtos secundários podem ser diretamente reutilizados como matérias-primas em outros processos industriais. Neste contexto, este trabalho apresenta a caracterização, do ponto de vista de suas propriedades físicas e químicas, de um lodo gerado em processo industrial de anodização de alumínio e enfatiza o potencial de sua aplicação como uma matéria-prima para a produção de espumas cerâmicas. As espumas cerâmicas foram produzidas a partir de esponja industrial de poliuretano, PU (método da réplica) com tamanho de poros ou células abertas de 10±5 ppi (porosidade=97%), as quais foram impregnadas com suspensões contendo teores mássicos de 50% a 61% de alumina (calcinada e moída), 1% de ácido cítrico, 6% de bentonita e queimados a 1600°C por 2 h. Os resultados deste trabalho mostram que o lodo de anodização de alumínio apresenta elevados teores mássicos de alumina (87,5%) e constância composicional bem como um relativamente pequeno tamanho médio de partículas (1,6 m), após calcinação e moagem. As espumas cerâmicas obtidas apresentaram porosidade de aproximadamente 70%, capacidade de filtração (vazão mássica de água) de 1,7 kg/s e resistência mecânica à compressão de 2,36 MPa. Assim, pode-se concluir que o lodo de anodização de alumínio pode ser uma matéria-prima alternativa para a produção de espumas cerâmicas, sendo aplicadas como filtros com propriedades adequadas para a filtração e purificação de metais fundidos para a obtenção de componentes com melhores desempenhos
Differential regulation of central vasopressin receptors in transgenic rats with low brain angiotensinogen
No full textThe consequences of permanent alteration to the brain renin-angiotensin system (RAS) on central vasopressinergic system was studied in transgenic rats with low brain angiotensinogen [TGR(ASrAOGEN)]. Levels of vasopressin (AVP) and V1a receptor mRNAs were measured by ribonuclease protection assay (RPA) and AVP by radioimmunoassay (RIA). AVP (100 pmol/50nl) was microinjected into the nucleus tractus solitarii (NTS) of urethane-anesthetized TGR(ASrAOGEN) and Sprague-Dawley (SD) rats and the mean arterial pressure (MAP) and heart rate (HR) baroreflex induced by phenylephrine were evaluated. AVP but not its mRNA levels were significantly lower in the hypothalamus and hypophysis of TGR(ASrAOGEN) rats. Brainstem V1a mRNA levels were significantly higher in TGR(ASrAOGEN) in comparison to SD rats (5.2±0.4% vs. 3.3±0.2% of β-actin mRNA, P<0.05). In contrast, the hypothalamic V1a mRNA levels in TGR(ASrAOGEN) were not different from those found in SD rats. AVP microinjections induced a greater decrease in MAP in TGR(ASrAOGEN) in comparison with SD rats (-19.9±5.2 vs. -7.5±0.7 mm Hg, P<0.01). The significantly higher baroreflex sensitivity observed in TGR compared to that of SD rats was normalized after AVP microinjection. The increased brainstem V1a mRNA levels and sensitivity to AVP in TGR(ASrAOGEN) rats indicates a functional upregulation of AVP receptors in the NTS. The fact that the hypothalamic V1a mRNA levels are not altered indicates that these receptors are differentially regulated in different brain regions. This study demonstrates that a permanent deficit in brain angiotensinogen synthesis can alter the functionality of central vasopressinergic system
