715,466 research outputs found

    Heterogeneity, distribution, and cooperation in common property resource management

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    The report considers the role of group heterogeneity in the success or failure of common property resource management. The author argues that cooperative agreements are less likely to come about when agents are highly heterogeneous along relevant dimensions - and existing agreements are more likely to break down as a group becomes more heterogeneous. The author crystallizes his argument in simple numerical examples and illustrates by reference to case studies on common property resource management, in particular, cases involving fisheries and irrigation systems. More work is needed to substantiate the author's argument, but his analysis so far supports the argument that equity and efficiency complement rather than oppose each other.Agricultural Research,Agricultural Knowledge&Information Systems,Poverty Assessment,Common Property Resource Development,Environmental Economics&Policies

    Hundreds of variants clustered in genomic loci and biological pathways affect human height

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    Most common human traits and diseases have a polygenic pattern of inheritance: DNA sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA) studies have identified more than 600 variants associated with human traits(1), but these typically explain small fractions of phenotypic variation, raising questions about the use of further studies. Here, using 183,727 individuals, we show that hundreds of genetic variants, in at least 180 loci, influence adult height, a highly heritable and classic polygenic trait(2,3). The large number of loci reveals patterns with important implications for genetic studies of common human diseases and traits. First, the 180 loci are not random, but instead are enriched for genes that are connected in biological pathways (P = 0.016) and that underlie skeletal growth defects (P<0.001). Second, the likely causal gene is often located near the most strongly associated variant: in 13 of 21 loci containing a known skeletal growth gene, that gene was closest to the associated variant. Third, at least 19 loci have multiple independently associated variants, suggesting that allelic heterogeneity is a frequent feature of polygenic traits, that comprehensive explorations of already-discovered loci should discover additional variants and that an appreciable fraction of associated loci may have been identified. Fourth, associated variants are enriched for likely functional effects on genes, being over-represented among variants that alter amino-acid structure of proteins and expression levels of nearby genes. Our data explain approximately 10% of the phenotypic variation in height, and we estimate that unidentified common variants of similar effect sizes would increase this figure to approximately 16% of phenotypic variation (approximately 20% of heritable variation). Although additional approaches are needed to dissect the genetic architecture of polygenic human traits fully, our findings indicate that GWA studies can identify large numbers of loci that implicate biologically relevant genes and pathways

    The Perfect Storm: The Political Economy of the Fischler Reforms of the Common Agricultural Policy. CEPS Paperbacks. September 2008

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    For decades, the Common Agricultural Policy came in for a significant amount of criticism for consuming a disproportionate share of the EU budget, introducing market distortions, wasting government funds and contributing to rural inequities. Nevertheless, it survived many attempts to abolish it, and acquired a reputation for being virtually impossible to reform in any meaningful way. However, during the tenure of Franz Fischler as European Commissioner for Agriculture from 1995 to 2004, the most radical reform in the history of the CAP was implemented. This book is the first to review the reforms that were implemented, to analyse how they came about and to explain which forces made them possible. It brings together perspectives from inside and outside the policy community, including from those closely involved in the policy debates, and an interdisciplinary perspective from economists and political scientists. The authors are senior policy-makers and well-respected academics. The book gives some fascinating insights into what made the reforms possible, offers useful conclusions on what this implies for future attempts at reform and finally, addresses the question of whether the Fischler reforms ‘scrapped the CAP’ or saved it

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Direct evidence of extensive diversity of HIV-1 in Kinshasa by 1960

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    Human immunodeficiency virus type 1 (HIV-1) sequences that pre-date the recognition of AIDS are critical to defining the time of origin and the timescale of virus evolution. A viral sequence from 1959 (ZR59) is the oldest known HIV-1 infection. Other historically documented sequences, important calibration points to convert evolutionary distance into time, are lacking, however; ZR59 is the only one sampled before 1976. Here we report the amplification and characterization of viral sequences from a Bouin's-fixed paraffin-embedded lymph node biopsy specimen obtained in 1960 from an adult female in Léopoldville, Belgian Congo (now Kinshasa, Democratic Republic of the Congo (DRC)), and we use them to conduct the first comparative evolutionary genetic study of early pre-AIDS epidemic HIV-1 group M viruses. Phylogenetic analyses position this viral sequence (DRC60) closest to the ancestral node of subtype A (excluding A2). Relaxed molecular clock analyses incorporating DRC60 and ZR59 date the most recent common ancestor of the M group to near the beginning of the twentieth century. The sizeable genetic distance between DRC60 and ZR59 directly demonstrates that diversification of HIV-1 in west-central Africa occurred long before the recognized AIDS pandemic. The recovery of viral gene sequences from decades-old paraffin-embedded tissues opens the door to a detailed palaeovirological investigation of the evolutionary history of HIV-1 that is not accessible by other method

    Tea time: not a crime to be poor

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    Weekly Tea Time program featuring Peter Edelman, author of "Not a crime to be poor", moderated by Khiara M. Bridges (BU School of Law).Boston University Howard Thurman Center for Common Groun

    Dr. Duane M. Jackson, Morehouse College, July 2011

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    This video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer

    Common Learning

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    Consider two agents who learn the value of an unknown parameter by observing a sequence of private signals. The signals are independent and identically distributed across time but not necessarily across agents. We show that that when each agent's signal space is finite, the agents will commonly learn its value, i.e., that the true value of the parameter will become approximate common-knowledge. In contrast, if the agents' observations come from a countably infinite signal space, then this contraction mapping property fails. We show by example that common learning can fail in this case.Common learning, common belief, private signals, private beliefs

    "Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.

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    "Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states. By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement. To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports

    Boat electrofishing survey of common smelt and common bullies in the Ohau Channel in December 2008

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    We conducted a boat electrofishing survey of the Ohau Channel, which flows from Lake Rotorua to Lake Rotoiti, on 11 December 2008. The purpose of this was to repeat a survey that took place on 13 December 2007 concerning the longitudinal pattern in densities of common smelt (Retropinna retropinna) and common bully (Gobiomorphus cotidianus). We caught 776 fish comprising three native species and three introduced species in 2.03km of fished distance at a total of 10 sites. Native species caught were common smelt, common bully and longfin eel (Anguilla dieffenbachii) and introduced species were rainbow trout (Oncorhynchus mykiss), goldfish (Carassius auratus) and mosquitofish (Gambusia affinis). The total area fished was 8,133 m² (0.813 ha) giving an estimated density of 9.5 fish 100 m⁻²
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