86 research outputs found
PERLINDUNGAN HAK KONSUMEN POMPA BENSIN MINI DI KECAMATAN MOGA KABUPATEN PEMALANG
No full textTechnological developments have given birth to many innovations, including in the business sector. Pom mini are a form of technological innovation carried out by business actors in buying and selling activities. The presence of the pom mini received a good response from the public. The design of the machine at pom mini which resembles a machine at a SPBU (public fuel filling station) is a special attraction for consumers. However, the unclear legal status of pom mini has the potential to harm consumers in buying and selling activities. With the presence of various innovations in buying and selling activities, people as consumers are required to be more critical of their rights in carrying out buying and selling activities.
This research was conducted using a juridical-empirical approach. This approach is carried out by examining laws that are conceptualized as real behavior or social phenomena that are not written in nature. This assessment can function to measure the effectiveness of the enactment of law in people's lives. In this research the author conducted research directly in Moga District, Pemalang Regency. The data collection process was carried out by interviews with related parties such as consumers, former business actors and related agencies. Apart from that, the author also made direct observations in the practice of buying and selling petrol at pom mini business activities in Moga District, Pemalang Regency.
This research obtained several results as follows: first, the practice of pom mini business activities in Moga District is not in accordance with the laws and regulations governing the protection of consumer rights in Indonesia. Second, there has been no clear action from the local government to provide legal protection for consumers because the licensing status of the pom mini business is unclear
Artificial intelligence and radiomics applications in adrenal lesions: a systematic review
No full textBackground: Adrenal lesions, often incidentally detected, present diagnostic challenges in distinguishing benign from malignant or hormonally active lesions. Conventional imaging (computed tomography/magnetic resonance imaging (CT/MRI)) has limitations, driving interest in artificial intelligence (AI) and radiomics for enhanced accuracy. Objectives: To systematically evaluate AI and radiomics applications in adrenal lesion characterization, focusing on diagnostic performance, methodologies, and clinical utility. Design: PRISMA-guided systematic review of studies published up to June 2024. Data sources and methods: PubMed, Scopus, Web of Science, and Google Scholar were searched using the keywords: adrenal lesions, AI, radiomics, and machine learning. Inclusion followed PICO criteria: patients with indeterminate lesions, AI/radiomics interventions, comparisons to standard diagnostics, and diagnostic accuracy. Two reviewers screened studies, resolving discrepancies via consensus. Eleven retrospective studies (996 patients) met eligibility. Results: CT-based radiomics (eight studies) achieved a mean AUC of 0.88 (range: 0.84–0.94) in differentiating benign/malignant or functional/non-functional lesions. Top-performing models identified aldosterone-producing adenomas (AUC: 0.99). MRI-based radiomics (three studies) yielded mean AUC: 0.82 (0.72–0.92), with test-set performance declines (e.g., AUC: 0.72) suggesting overfitting. Nuclear medicine (four studies) demonstrated that hybrid 18F-FDG PET/CT models (SUVmax + texture features) achieved an AUC of 0.97 for metastatic versus benign lesions. AI applications extended to intraoperative navigation (AUC: 0.93) and prognostic prediction. Conclusion: CT-based radiomics outperformed MRI, aligning with guidelines favoring CT for adrenal assessment. AI-enhanced models show promise in refining diagnostics and reducing invasive procedures. However, retrospective designs, small cohorts, and protocol variability limit generalizability. Future work requires multicenter collaboration, standardized protocols, and prospective validation to translate AI/radiomics into clinical practice
Analisis nilai-nilai pendidikan akhlak dalam film moga bunda disayang allah karya tere liye
No full textINDONESIA:
Pendidikan sedang berada di era digitalisasi pendidikan, ditengah generasi yang masih mudah tergerus dalam arus milenial. Maka proses pembelajaran guru hendaknya dapat menyentuh secara menyeluruh dimensi kemanusiaan baik fisik, ruh, akal, hati, dan nafsu dengan seimbang. Hal ini perlu ditumbuhkembangkan melalui penyempurnaan akhlak. Film merupakan media dengan kecanggihan efek audio visual yang tidak hanya sebagai media hiburan, namun dapat memberi pendidikan dan pengetahuan penonton. Film ini merupakan media yang sarat akan nilai-nilai pendidikan akhlak.
Rumusan masalah penelitian ini adalah: 1) Bagaimana nilai-nilai pendidikan akhlak yang terkandung dalam film “Moga Bunda Disayang Allah”?, 2) Bagaimana metode pembentukkan nilai-nilai pendidikan akhlak dalam film “Moga Bunda Disayang Allah” ?.3) Bagaimana pesan cerita dalam film “Moga Bunda Disayang Allah”?.
Penelitian ini menggunakan pendekatan penelitian kualitatif dengan jenis penelitian semiotik. Teknik pengumpulan data yang digunakan adalah metode dokumentasi. Data dianalisis dengan menggunakan analisis konten (content analysis), dengan mereduksi, memaparkan data dan menarik kesimpulan. Kemudian untuk pengecekkan keabsahan data, penulis menggunakan ketekunan pengamatan dan pengecekan teman sebaya.
Hasil penelitian menunjukkan bahwa: (1) Nilai-nilai pendidikan akhlak yang terkandung dalam film ‘Moga Bunda Disayang Allah” antara lain: iman dan takwa, tolong-menolong, tenang, mengasihi, sopan santun, sabar, ikhlas, husnuzon, bersyukur, dan silaturahmi. (2) Metode pembentukkan nilai-nilai pendidikan akhlak dalam film “Moga Bunda Disayang Allah”antara lain: muhasabah (introspeksi diri), mujahadah (bersungguh-sungguh), dan riyadhah (membiasakan). (3) Senantiasa tolong-menolong terhadap sesama dengan ikhlas, bersabar akan segala ketetapan Allah SWT., tidak mudah berputus asa dengan rahmat Allah SWT., selalu setia atau selalu membalas kebaikan dengan kebaikan bagi orang lain yang telah menolong kita dengan tulus, dan bertanggung jawab atas segala amanah yang telah dipercayakan kepadanya.
INGGRIS:
Education is in the era of digitizing education, amid a generation that is still easily eroded in millennial flows. So the teacher learning process should be able to touch thoroughly the dimensions of humanity both physically, spirit, mind, heart, and lust in a balanced manner. This needs to be developed through moral improvement. Film is a media with sophisticated audio-visual effects not only as entertainment media, but can provide education and knowledge of the audience. This film is a media which is full of moral education values.
The formulation of the problem of this research are: 1) What are the values of moral education contained in the film "Moga Bunda Disayang Allah"?. 2) What is the method of forming the values of moral education in the film "Moga Bunda Disayang Allah"? 3) What is the message of the story in the film "Moga Bunda Disayang Allah” ?.
This research uses a qualitative research approach to the type of semiotic research. The data collection technique used is the documentation method. Data were analyzed using content analysis, by reducing, describing data and drawing conclusions. Then to check the validity of the data, the author uses perseverance of observation and peer checking.
The results showed that: (1) The values of moral education contained in the film “Moga Bunda Disayang Allah” include: faith and piety, help, help, calm, love, courtesy, patience, sincerity, husnuzon, give thanks, and friendship. (2) Methods of forming the values of moral education in the film "Moga Bunda Disayang Allah" include: muhasabah (self-introspection), mujahadah (earnest), and riyadhah (getting used). (3) Always help others with sincerity, be patient with all the provisions of Allah SWT, do not easily despair with the grace of Allah SWT, always loyal or always repay kindness with kindness to others who have helped us sincerely, and are responsible responsible for all the mandate that has been entrusted to him.
ARAB:
التعليم في عصر رقمنة التعليم ، وسط جيل لا يزال يتآكل بسهولة في تدفقات الألفية. لذا يجب أن تكون عملية تعلم المعلم قادرة على لمس أبعاد الإنسانية بشكل كامل جسديًا وروحًا وعقلًا وقلبًا وشهوة بطريقة متوازنة. هذا يحتاج إلى تطوير من خلال التحسين الأخلاقي. الفيلم عبارة عن وسائط ذات تأثيرات سمعية بصرية متطورة ليس فقط كوسيلة ترفيه ، ولكن يمكنها توفير التعليم والمعرفة للجمهور. هذا الفيلم وسيلة إعلامية مليئة بقيم التربية الأخلاقية
صياغة مشكلة هذا البحث هي: 1) ما هي قيم التربية الأخلاقية الواردة في فيلم " موغا بوندا دي ساياع الله" ؟، 2) كيف يتم تشكيل قيم التربية الأخلاقية في فيلم " موغا بوندا دي ساياع الله "؟ 3) ما رسالة القصة في فيلم " موغا بوندا دي ساياع الله"؟
تستخدم هذه الدراسة نهج البحث النوعي لنوع البحث السيميائي. تقنية جمع البيانات المستخدمة هي طريقة التوثيق. تم تحليل البيانات باستخدام تحليل المحتوى ، عن طريق الحد ، ووصف البيانات واستخلاص النتائج. ثم للتحقق من صحة البيانات، والاستخدامات المؤلف المثابرة للمراقبة والتحقق من الأقران
أظهرت النتائج ما يلي: (1) قيم التربية الأخلاقية الواردة في فيلم "موغا بوندا دي ساياع الله" تشمل: الإيمان والتقوى ، العون ، المساعدة ، الهدوء ، الحب ، المجاملة ، الصبر ، الإخلاص ، الحسنون ، الشكر ، والصداقة. . (2) طرق تشكيل قيم التربية الأخلاقية في فيلم " موغا بوندا دي ساياع الله" تشمل: (الاستبطان الذاتي) ، المجاهدة ، والريادة (التعود). (3) ساعد الآخرين دائمًا بإخلاص ، وتحلى بالصبر مع جميع أحكام الله سبحانه وتعالى ، ولا تيأس بسهولة بفضل الله ، وغالبًا ما تكون مخلصًا أو دائمًا تعيد اللطف مع الآخرين الذين ساعدونا بإخلاص ، وهم مسؤولون على كل التفويض الموكول إلي
GAYA BAHASA DALAM NOVEL MOGA BUNDA DISAYANG ALLAH KARYA TERE LIYE
No full textAbstrak: Penelitian ini dilatarbelakangi oleh keinginan penulis untuk menemukan gaya bahasa dalam novelMoga Bunda Disayang Allah karya Tere Liye. Penelitian ini bertujuan untuk mendeskripsikan gaya bahasa yang terdapat dalam novelMoga Bunda Disayang Allahkarya Tere Liye. Penelitian ini menggunakan metode deskriptif. Bentuk penelitian yang digunakan adalah pendekatan stilistika. Teknik yang digunakan dalam penelitian ini adalah teknik dokumenter. Analisis data dilakukan dengan cara menganalisis data yang telah diklasifikasikan.Berdasarkan analisis data, penelitian ini menghasilkan simpulan sebagai berikut: 1) gaya bahasa perbandingan meliputi hiperbola, metafora, metonimia, personifikasi, perumpamaan , alegori, sinekdoke, simile, asosiasi, epitet, eponym, pleonasme, eufemisme, pars pro toto; 2) gaya bahasa penegasan meliputi epifora, erotesis, paralelisme, klimaks, antiklimaks; 3) gaya bahasa pertentangan meliputi antithesis, okufasi, dan paradoks; 4) gaya bahasa sindiran yang meliputi sarkasme. Kata Kunci: gaya bahasa, novel Abstract: This research backed by desire writers to findthe figure of speech in novel Moga Bunda Disayang Allah karya Tere Liye. This research aims to describethe figure of speechspeech in novel Moga Bunda Disayang AllahTere Liye Author. This research using descriptive. The research used is stylistic approach. The technique used in this research is a documentary technique. Data analysis is done by analyzing the data that has been classified. Based on data analysis, This study yields the following conclusions: 1) the figure of speech comparison which includes hyperbole, methapor, metonymy, personification, parable, allegory, sinekdoke simile, associations, epithet, eponymous, redudancy, euphemisms and pars pro toto; 2) the figure of speech affirmation which includes epistrophe, erotesis,parallelism, climax and anticlimax; 3) the figure of speech contradictions which includes antithesis, occuption, and paradoxical; 4) the figure of speech allusions which includes sarcasm. Keywords : the figure of speech, novel
Eosinophilic Solid and Cystic Renal Cell Carcinoma—A Case Report and Literature Review
No full textEosinophilic solid and cystic renal cell carcinoma (ESC-RCC) is a novel and uncommon type of renal cell carcinoma, which has been recently recognized and introduced as a distinct entity in the WHO 2022 kidney tumor classification. Previously known as “unclassified RCC”, followed by “tuberous sclerosis complex (TSC)-associated RCC”, ESC-RCC is now a distinct category of kidney tumor, with its own name, with specific clinical manifestations, and a unique morphological, immunohistochemical and molecular profile. Due to its recent introduction and the limited available data, the diagnosis of ESC-RCC is still a complex challenge, and it is probably frequently misdiagnosed. The secret of diagnosing this tumor lies in the pathologists’ knowledge, and keeping it up to date through research, thereby limiting the use of outdated nomenclature. The aim of our case-based review is to provide a better understanding of this pathology and to enrich the literature with a new case report, which has some particularities compared to the existing cases
Multiple criteria optimization of electrostatic electron lenses using multiobjective genetic algorithms
No full textThe design of an electrostatic electron optical system with five electrodes and two objective functions is optimized using multiobjective genetic algorithms (MOGAs) optimization. The two objective functions considered are minimum probe size of the primary electron beam in a fixed image plane and maximum secondary electron detection efficiency at an in-lens detector plane. The time-consuming step is the calculation of the system potential. There are two methods to do this. The first is using COMSOL (finite element method) and the second is using the second-order electrode method (SOEM). The former makes the optimization process very slow but accurate, and the latter makes it fast but less accurate. A fully automated optimization strategy is presented, where a SOEM-based MOGA provides input systems for a COMSOL-based MOGA. This boosts the optimization process and reduces the optimization times by at least ∼10 times, from several days to a few hours. A typical optimized system has a probe size of 11.9 nm and a secondary electron detection efficiency of 80%. This new method can be implemented in electrostatic lens design with one or more objective functions and multiple free variables as a very efficient, fully automated optimization technique. ImPhys/Microscopy Instrumentation & TechniquesDC systems, Energy conversion & Storag
成人T細胞白血病リンパ腫に対するモガムリズマブの治療成績に関する臨床的検討
No full textAdult T-cell leukemia–lymphoma (ATL) is a distinct T-cell malignancy caused by human T-cell leukemia virus type-1; the prognosis is very poor. Mogamulizumab (Moga), an antibody drug for CC chemokine receptor type 4, has been introduced for the treatment of ATL. However, the prognosis of relapsed or refractory ATL remains poor and the characteristics of patients who derive clinical benefit from treatment with Moga remain poorly understood. We analyzed the associations of clinical factors with the outcome after Moga treatment. Forty-five patients treated with Moga monotherapy were evaluated. The median age of the patients was 69 years, and 40% were female. The median overall survival (OS) time was 17.6 months and the 2-year OS rate was 43.2%. Number of prior therapies and response to prior therapy were predictive clinical features in univariate analysis for OS. Performance status, corrected serum calcium level, serum lactate dehydrogenase level, Japan Clinical Oncology Group-prognostic index (PI), and simplified ATL-PI at Moga treatment were also associated with the prognosis after Moga monotherapy. Improved understanding of the clinical factors predicting the prognosis after Moga may contribute to improved treatment strategies for ATL.長崎大学学位論文 学位記番号:博(医歯薬)甲第1127号 学位授与年月日:平成31年3月6日Author: Jun Nakashima, Yoshitaka Imaizumi, Hiroaki Taniguchi, Koji Ando, Masako Iwanaga, Hidehiro Itonaga, Shinya Sato, Yasuhi Sawayama, Tomoko Hata, Shinichiro Yoshida, Yukiyoshi Moriuchi, Yasushi MiyazakiCitation: International Journal of Hematology, 108(5), pp.516-523; 201
Decrease in prostate cancer detection during COVID-19 pandemic
No full textBackground and objectives: The aim of this study was to evaluate the
impact of the COVID-19 pandemic on the detection of prostate cancer in men
considered at high risk. This was done by comparing data from the Mures County
Clinical Hospital, Clinic of Urology one year before (non-pandemic, NP) and
during (pandemic, P) the global COVID-19 pandemic.
Methods: A retrospective study was performed based on the Mures County
Clinical Hospital database. The inclusion criteria were clinical suspicion
(digital rectal examination) and elevated prostate-specific antigen (PSA) level
(threshold 3.2 ng/mL). Statistical analysis was performed with STATA 11 Program.
Mann-Whitney, Student and chi-square tests were used to compare median PSA,
prostate volume, number of TRUSbx performed, number of core biopsies, Gleason
Score values, and perineural invasion between the NP and P groups.
Results: A total of 440 patients were studied, comprising 271 in the NP
group and 169 in the P group. The average number of TRUSbx procedures was 22.58
per month in 2019 (NP group) and 14.08 per month in 2020 (P group), representing
a decrease of 37.65%. Analysis of data for the P and NP groups showed a median
PSA of 10.48 vs 10.58, mean prostatic volume of 43.69 vs 43.26, number of core
biopsies 11.39 vs 11.70, and Gleason score of 7.31 vs 7.15, respectively.
Mann-Whitney U test revealed no statistically significant differences between the
two groups, with only the Gleason Score showing a trend for significance
(p = 0.065).
Conclusions: The COVID-19 pandemic led to a major decrease in the
number of surgeries performed, with TRUSbx declining by almost 40%. No
differences between P and NP periods were observed for median PSA, prostate
volume, number of core biopsies, and perineural invasion. The Gleason Score
showed a slightly higher incidence of advanced prostate cancer in the P group,
but this did not reach statistical significance
ALTERNATIVES IN CONTEMPORARY OPERA STAGING. "HÄNSEL AND GRETEL" BY ENGELBERT HUMPERDINCK AND THE INPUT OF THE TECHNICAL DIRECTOR
No full textUntil around 1940, the complex work of opera staging was divided between orchestra conductors, designers and technical directors. Gradually, however, staging became “a passion (...) for critics, aesthetes, and scholars, an ambition for leading actors, and an incessant problem for the directors of opera houses." There was a constant need for the emergence of directing specialists in the artistic environment, and their role became increasingly flexible in the period immediately following World War II. Nowadays, opera directors are virtual creators having multiple options at hand with regard to staging. They can choose from classical, traditional staging, where observing the intentions of the author is a prerequisite, to a contemporary, more up-to-date directing approach, where the subject of the opera is transposed into a different time and space, implying, at the same time, a reinterpretation and adaptation of codes. They can also resort to the so-called "modern", radical directing, where opera itself becomes a mere tool used to comply with the director\u27s intentions. We consider the staging of the opera Hänsel and Gretel at the Romanian National Opera House in Cluj-Napoca between 2006 and 2015 as our personal follow out to the traditional staging practice, as a technical director
ALTERNATIVES IN CONTEMPORARY OPERA STAGING. "HÄNSEL AND GRETEL" BY ENGELBERT HUMPERDINCK AND THE INPUT OF THE TECHNICAL DIRECTOR
No full textUntil around 1940, the complex work of opera staging was divided between orchestra conductors, designers and technical directors. Gradually, however, staging became “a passion (...) for critics, aesthetes, and scholars, an ambition for leading actors, and an incessant problem for the directors of opera houses." There was a constant need for the emergence of directing specialists in the artistic environment, and their role became increasingly flexible in the period immediately following World War II. Nowadays, opera directors are virtual creators having multiple options at hand with regard to staging. They can choose from classical, traditional staging, where observing the intentions of the author is a prerequisite, to a contemporary, more up-to-date directing approach, where the subject of the opera is transposed into a different time and space, implying, at the same time, a reinterpretation and adaptation of codes. They can also resort to the so-called "modern", radical directing, where opera itself becomes a mere tool used to comply with the director's intentions. We consider the staging of the opera Hänsel and Gretel at the Romanian National Opera House in Cluj-Napoca between 2006 and 2015 as our personal follow out to the traditional staging practice, as a technical director
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