2,335 research outputs found

    sj-xlsx-5-tam-10.1177_17588359211038478 – Supplemental material for Comprehensive molecular profiling to predict clinical outcomes in pancreatic cancer

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    Supplemental material, sj-xlsx-5-tam-10.1177_17588359211038478 for Comprehensive molecular profiling to predict clinical outcomes in pancreatic cancer by Jung Yong Hong, Hee Jin Cho, Seung Tae Kim, Young Suk Park, Sang Hyun Shin, In Woong Han, Jeeyun Lee, Jin Seok Heo and Joon Oh Park in Therapeutic Advances in Medical Oncology</p

    sj-tif-3-tam-10.1177_17588359211038478 – Supplemental material for Comprehensive molecular profiling to predict clinical outcomes in pancreatic cancer

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    Supplemental material, sj-tif-3-tam-10.1177_17588359211038478 for Comprehensive molecular profiling to predict clinical outcomes in pancreatic cancer by Jung Yong Hong, Hee Jin Cho, Seung Tae Kim, Young Suk Park, Sang Hyun Shin, In Woong Han, Jeeyun Lee, Jin Seok Heo and Joon Oh Park in Therapeutic Advances in Medical Oncology</p

    sj-tif-1-tam-10.1177_17588359211038478 – Supplemental material for Comprehensive molecular profiling to predict clinical outcomes in pancreatic cancer

    No full text
    Supplemental material, sj-tif-1-tam-10.1177_17588359211038478 for Comprehensive molecular profiling to predict clinical outcomes in pancreatic cancer by Jung Yong Hong, Hee Jin Cho, Seung Tae Kim, Young Suk Park, Sang Hyun Shin, In Woong Han, Jeeyun Lee, Jin Seok Heo and Joon Oh Park in Therapeutic Advances in Medical Oncology</p

    sj-tif-2-tam-10.1177_17588359211038478 – Supplemental material for Comprehensive molecular profiling to predict clinical outcomes in pancreatic cancer

    No full text
    Supplemental material, sj-tif-2-tam-10.1177_17588359211038478 for Comprehensive molecular profiling to predict clinical outcomes in pancreatic cancer by Jung Yong Hong, Hee Jin Cho, Seung Tae Kim, Young Suk Park, Sang Hyun Shin, In Woong Han, Jeeyun Lee, Jin Seok Heo and Joon Oh Park in Therapeutic Advances in Medical Oncology</p

    sj-tif-4-tam-10.1177_17588359211038478 – Supplemental material for Comprehensive molecular profiling to predict clinical outcomes in pancreatic cancer

    No full text
    Supplemental material, sj-tif-4-tam-10.1177_17588359211038478 for Comprehensive molecular profiling to predict clinical outcomes in pancreatic cancer by Jung Yong Hong, Hee Jin Cho, Seung Tae Kim, Young Suk Park, Sang Hyun Shin, In Woong Han, Jeeyun Lee, Jin Seok Heo and Joon Oh Park in Therapeutic Advances in Medical Oncology</p

    Atypical Integration of Sensory-to-Transmodal Functional Systems Mediates Symptom Severity in Autism

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    A notable characteristic of autism spectrum disorder (ASD) is co-occurring deficits in low-level sensory processing and high-order social interaction. While there is evidence indicating detrimental cascading effects of sensory anomalies on the high-order cognitive functions in ASD, the exact pathological mechanism underlying their atypical functional interaction across the cortical hierarchy has not been systematically investigated. To address this gap, here we assessed the functional organisation of sensory and motor areas in ASD, and their relationship with subcortical and high-order trandmodal systems. In a resting-state fMRI data of 107 ASD and 113 neurotypical individuals, we applied advanced connectopic mapping to probe functional organization of primary sensory/motor areas, together with targeted seed-based intrinsic functional connectivity (iFC) analyses. In ASD, the connectopic mapping revealed topological anomalies (i.e., excessively more segregated iFC) in the motor and visual areas, the former of which patterns showed association with the symptom severity of restricted and repetitive behaviors. Moreover, the seed-based analysis found diverging patterns of ASD-related connectopathies: decreased iFCs within the sensory/motor areas but increased iFCs between sensory and subcortical structures. While decreased iFCs were also found within the higher-order functional systems, the overall proportion of this anomaly tends to increase along the level of cortical hierarchy, suggesting more dysconnectivity in the higher-order functional networks. Finally, we demonstrated that the association between low-level sensory/motor iFCs and clinical symptoms in ASD was mediated by the high-order transmodal systems, suggesting pathogenic functional interactions along the cortical hierarchy. Findings were largely replicated in the independent dataset. These results highlight that atypical integration of sensory-to-high-order systems contributes to the complex ASD symptomatology

    Chinese literary works translated into Baba Malay: a bibliographical study

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    Analyses 68 unique titles of Baba translated works published between 1889 and 1950. The titles are held in the libraries of the University of Malaya (UM), Science University Malaysia (USM), National University of Malaysia (UKM), the Dewan Bahasa dan Pustaka (DBP), National University of Singapore (NUS), National Library of Singapore (NLS) and the British Library (BL). The results reveal three periods of active publication of Baba translated works. A total of 18 works were translated before World War I, followed by 10 just after the war, 39 titles were published before the break of the World War II and 1 was identified in 1950. There were 103 persons involved in the 68 translated works, some of whom are responsible for more than one title. The most prominent translators were Chan Kim Boon, Wan Boon Seng, Seow Chin San and Lee Seng Poh. Some of the translators were also be editors, illustrators or editors. There were 31 publishers and 21 printing presses involved, all were located in Singapore. The most active publishers were Wan Boon Seng, Kim Seck Chy Press and Nanyang Romanised Malay Book Co. The translated works mainly cover historical classical Chinese stories, chivalrous stories, romances, folklore and legends. The titles were priced between 10 cents to 2 dollars in Straits currency. The University of Malaya Library held the largest number of unique title (62) out of which 15 were unique titles
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