210 research outputs found
Strength in Numbers : An Art of Life
No full textArt, often through metaphors, depicts that which is visible, while Science works hard to uncover what is hidden and yet unknown, making the two realms appear seemingly at odds with each other. However, both these endeavors are complementary in their pursuit of interpreting the physical world and communicating that vision to humanity. This image is a representation of my research in theoretical biophysics through my artwork. I work on living or 'Active' systems, like birds, fish and bacteria, which show a wide range of spectacular community phenomena of which no analogue can be found in the inanimate world. In this image we see schools of fish self-organize into travelling density waves (top right), coherently moving clusters (middle) and swirls (bottom), just a few of many such fantastic collective behavior that living systems exhibit. Indeed, there is strength in numbers: by flocking, these living entities ensure that they are protected from predation and environmental shocks. Such self-organization into collective structures is spontaneous, intriguing and often breath-taking, and as such captures the imagination of artists and scientists alike.Open Restriction set for Item 110825 on 2019-05-07T20:26:32Z with date null by [email protected] by Emilie Staubs ([email protected]) on 2019-05-07T20:28:16Z
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Previous issue date: 2019Ope
Non-equilibrium physics of driven living matter
No full textThe student, Purba Chatterjee, submitted this Dissertation for approval on 2021-05-07 at 09:11.In this dissertation, I explore how complex macroscopic collective phases emerge from stochastic interactions of the components of a biological system. In addition, I examine the conditions for non-equilibrium transitions from one stable phase to another. This dissertation is divided into two parts. Part I concerns systems broadly classified as active matter. I focus on three specific examples of emergent collective phases in active systems: flocking, chemotactic aggregation, and emergent elasticity.
1. Flocking:- I study the transition to long-range orientational order in polar active systems with a simple agent-based model for flocking, as well as its derived stochastic hydrodynamics. Through exact Gillespie simulations and analytical calculations, I show that binary interactions are insufficient to generate polar order, in agreement with experimental studies on actomyosin assays. However, noisy three-body interactions are both necessary and sufficient to capture the complete phenomenology of the flocking transition at high densities. I further show that imposition of skewed noise statistics can generate artifactual polar order with just two-body interactions. Moreover, the intrinsic stochasticity of microscopic interactions predicts a new phase at low densities mediated by just two-body interactions. This phase, characterized by transient local order, has been identified experimentally in fish schools.
2. Chemotactic aggregation:- I develop a field-theoretic description for active systems, based on a density functional description of crystalline materials modified to capture orientational ordering. I enumerate the many advantages offered by this framework in studying collective phases in active systems, with particle resolution, but on diffusive timescales. Modifying it to describe run and tumble chemotaxis, I show that this model can capture particle aggregation in an externally imposed constant attractant field, as observed for phototactic or thermotactic agents. I also show that this model captures particle aggregation through self-chemotaxis, an important mechanism that aids quorum dependent cellular interactions.
3. Emergent elasticity:- I demonstrate that agent-based models, with simple rules governing the reaction of individual agents to controlled perturbations, can capture experimentally-observed emergent elastic responses in biological systems. I also motivate a formal elastic theory for active systems based on a density functional description of crystalline materials, and discuss the potential as well as the challenges of this formalism.
Part II concerns transcription, the process by which molecular machines called RNA polymerases (RNAPs), synthesize messenger RNA (mRNA) from the genome. I study the purely mechanical regulation of collective modes of RNAP dynamics through transcription-induced DNA supercoiling. I formulate a continuum deterministic model for the translocation of RNAPs on a typical gene, where the speed of an RNAP is coupled to the local DNA supercoiling as well as the density of RNAPs on the gene. Moreover, I propose that transcription factors can act as physical barriers to the diffusion of DNA supercoils. I show that unlike existing theories, this model successfully recapitulates the recent experimental observation that DNA supercoiling drives a transition from cooperative to antagonistic RNAP dynamics when RNAP loading is interrupted. The novel hypotheses that form the basis of this model have important implications for transcription dynamics in the genomic context, where genes may affect each other's transcription efficiencies from a long distance via supercoil diffusion. As such, this work presents an important stepping stone towards understanding the collective dynamics of the molecular machines involved in gene expression.Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-01-12 without embargo termsThe student, Purba Chatterjee, accepted the attached license on 2021-05-07 at 09:05.This Dissertation was approved for publication on 2021-05-13 at 14:35.DSpace SAF Submission Ingestion Package generated from Vireo submission #16640 on 2022-01-12 at 12:42:26Made available in DSpace on 2022-01-12T21:40:28Z (GMT). No. of bitstreams: 3
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Previous issue date: 2021-05-1
A Study of Figurative Language Found in Bruno Mars’ Selected Songs
No full textThe title of this paper is “A Study of Figurative Language Found in Bruno Mars’ Selected Songs”. Figurative language is one of style of language that the way to convey it is different from the real meaning. Figurative language is very common in song or poetry. This is very useful to writer because it can make their language more beautiful and interesting to listen. Figurative convey shades of meaning that can’t be expressed exactly any other way. Author will describe about figurative and the meaning for the lyrics that contain figurative. The method that the author used in this paper is qualitative-library research where the author collects some book that relevant with this topic. In this paper, author will focus on four types of figurative which are simile, metaphor, hyperbole and, personification. The aim was to know the figurative language used in Bruno Mars’ songs and to portray the meanings found in the lyrics.Paper ini berjudul “A Study of Figurative Language Found in Bruno Mars’ Selected Songs”. Bahasa kiasan merupakan salah satu gaya bahasa yang cara menyampaikannya berbeda dari makna sebenarnya. Bahasa kiasan sangat umum di dalam lagu atau puisi. Ini sangat bermanfaat bagi penulis karena dapat membuat bahasa mereka lebih indah dan menarik untuk di dengarkan. Kiasan menyampaikan bayangan dari suatu makna yang tidak begitu bisa di ekspresikan dengan cara lain. Penulis akan menjelaskan kiasan dan arti dari lirik lagu yang mengandung kiasan. Metode yang digunakan penulis dalam kertas karya ini adalah metode penelitian kepustakaan dimana penulis mengumpulkan beberapa buku yang berhubungan dengan topik ini. Dalam kertas karya ini penulis akan fokus dengan empat tipe kiasan yaitu asosiasi (simili), metafora, hiperbola, dan personifikasi. Tujuannya adalah untuk mengetahui bahasa kiasan yang digunakan di lagu milik Bruno Mars dan menggambarkan arti lirik tersebut.Kertas Karya Diplom
Impacts of medical and wellness tourism centers on the communities around them: case studies in Delhi and Kerala
No full textOver the past decade or so the movement of patients and wellness seekers across borders, over long distances, has increased and India has been the destination of choice for many. This is private sector led growth, but the government has provided support in terms of subsidies and its promotion. With the alignment of governmental support and other enabling circumstances, many new centers-both corporate hospitals and Ayurvedic wellness centers-have opened in India. The case studies for this research were centers in Delhi, for medical tourism, and Kerala, for wellness tourism. This study involved assessing the impacts of these centers on the local communities around them, in terms of medical, economic, and infrastructural consequences. Another question was whether these centers formed enclaves, of varying degrees, where the impacts were focused, or were there significant benefits for these communities from the centers being there. The flow of benefits to the locals, in terms of access to healthcare and other economic and infrastructural impacts was limited, more so around the wellness tourism centers. Many, living close to these centers, could not afford the facilities because of the expense involved. All the medical tourism centers in the study were built on land given at concessional rates, with the promise that the hospitals would reserve a certain percentage of their outpatient and inpatient capacities for people below poverty level. Most of these hospitals have failed to follow that. In terms of other benefits, some local businesses and the accommodation sector have benefitted from these centers being located in their neighborhoods.Ph. D.Includes bibliographical referencesIncludes vitaby Purba Rudr
The Role of the Community in Village Development in the Ancient Village of Dolok, Doloksanggul District, Humbang Hasundutan Regency
No full text64 HalamanPada penelitian ini, peran masyarakat dalam pembangunan masih tergolong pasif,
hal ini terlihat dari sebagian masyarakat yang tidak peduli pada pembangunan
desa yang akan dilaksanakan. Tujuan penelitian ini ialah untuk mengetahui peran
masyarakat dalam pembangunan dan untuk mengetahui penghambat peran
masyarakat dalam pembangunan desa di desa Purba Dolok. Pada penelitian ini,
jenis penelitian yang dilakukan oleh penulis adalah metode pendekatan deskriptif
kualitatif, yang menjelaskan permasalahan yang ada dalam bentuk kata dan tulisan
dalam setiap kejadian yang ada. Indikator dari peran masyarakat desa Purba
Dolok peran sebagai kebijakan, berupa argumentasi seperti penempatan
bangunan, memperhatikan daya tahan bangunan dan pemeliharaan bangunan.
Kemudian, peran sebagai strategi dimana masyarakat yang bekerjasama dengan
perangkat desa dalam menyusun strategi pelaksanaan pembangunan berupa
persiapan lokasi, penyesuaian dana anggaran dan pembentukan kelompok kerja.
Peran sebagai komunikasi, dalam hal ini komunikasi masyarakat desa dan
perangkat desa memberikan informasi kepada masyarakat melalui kepala dusun
yang bertanggung jawab dilingkungan tiap dusun. Peran sebagai alat penyelesaian
sengketa, dalam hal ini cara yang dilakukan dalam meredam perbedaan pendapat
maupun konflik yang timbul, diadakannya musyawarah desa untuk pemungutan
suara supaya dapat mengatasi perbedaan pendapat yang muncul pada saat
musyawarah desa dilaksanakan. In this study, the role of the community in development is still relatively passive,
this can be seen from some people who do not care about the village development
that will be carried out. The purpose of this study is to find out the role of the
community in development and to find out the obstacles to the role of the
community in village development in the village of Purba Dolok. In this study, the
type of research carried out by the author is a qualitative descriptive approach
method, which explains the problems that exist in the form of words and writing in
every existing event. Indicators of the role of the Purba Dolok village community
as a policy role, in the form of arguments such as building placement, paying
attention to building durability and building maintenance. Then, the role as a
strategy where the community cooperates with village officials in developing
strategies for the implementation of development in the form of site preparation,
adjustment of budget funds and the formation of working groups. The role as
communication, in this case, the communication of the village community and
village officials provide information to the community through the head of the
hamlet who is responsible for the environment of each hamlet. The role as a
dispute resolution tool, in this case the way that is carried out in reducing
differences of opinion and conflicts that arise, the holding of village deliberations
for voting in order to overcome differences of opinion that arise when village
deliberations are held
Strategi Komunikasi Muhammadiyah dalam Menebar Dakwah Kultural Persfektif Muhammad Abu Fatah Al-Bayanuni (Studi Kasus: Muhammadiyah Bangun Purba Deli Serdang)
No full textIn this study the authors wanted to know the Communication Strategy of the Muhammadiyah Bangun Purba Branch Leaders in spreading cultural da'wah. The author uses Muhammad Abu Fatah Al-Bayanuni's Da'wah Strategy Theory, including: Athifiy Da'wah Strategy, Aqliy Strategy, and Hissiy Method. In this study the authors used descriptive qualitative research. In collecting data the authors used three techniques, namely: participant observation, in-depth interviews, and documentation. Data validity technique with credibility test. Data analysis techniques using the Miles & Huberman model. Muhammadiyah Bangun Purba Branch Manager has its own communication strategy in spreading cultural da'wah, in carrying out the tradition of the Seven Months of Pregnancy, it is more advisable for Persyarikatan residents to Al-Quran recitations during the pregnancy process without having to enter the seventh month of pregnancy. Whereas in the Tahlilan tradition of Sending Prayers for people who have died, the Muhammadiyah Bangun Purba Branch Leader forbade it to be carried out, Muhammadiyah Bangun Purba members prioritize the nature of respecting and maintaining friendship. To show the existence that Muhammadiyah is not anti-art culture, currently the Branch Manager Muhammadiyah Bangun Purba has a dance and Martial Arts studio, Tapak Suci
Optimization of retrofit decisions as risk mitigation strategies for infrastructure
No full textRetrofit actions have become one of the prominent strategies for infrastructure mitigation planning in reducing vulnerability to hazards. A retrofit action is the application of advanced devices or materials to enhance structural performance. There are three common considerations in the decision-making process of implementing retrofit actions, i.e., limited budgets and resources, the complexity and the size of infrastructure systems, and the uncertainties of the hazards. Considering these three aspects, this study formulates a general stochastic optimization problem to find the optimal retrofit for infrastructure. The optimization problem is formulated to examine two objectives, i.e., to minimize the total retrofit cost and the performance losses of the infrastructure. The proposed formulation uses the Matrix-based System Reliability method to estimate the uncertainty parameters and the Decomposition method to find the optimum solution. Then, the general formulation is used specifically for transportation systems to find the optimal retrofit decisions for bridges.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2022-08-01The student, Denissa Purba, accepted the attached license on 2020-07-22 at 16:10.The student, Denissa Purba, submitted this Thesis for approval on 2020-07-22 at 16:32.This Thesis was approved for publication on 2020-07-23 at 10:33.DSpace SAF Submission Ingestion Package generated from Vireo submission #15629 on 2020-10-02 at 15:50:51Made available in DSpace on 2020-10-07T22:49:59Z (GMT). No. of bitstreams: 2
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Previous issue date: 2020-07-23Embargo set by: Seth Robbins for item 116335
Lift date: 2022-10-07T22:50:13Z
Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemAuthor requested closed access (OA after 2yrs) in Vireo ETD systemLimite
Analisis Yuridis Dalam Peralihan Objek Jaminan Sebidang Tanah Secara Melawan Hukum (Studi Putusan Nomor 26/PDT.G/2021/PN.MDN)
No full textAt the present time, in people's lives, there are still many problems with verbal debts
and receivables which cause losses for one of the parties, for example due to the
transfer of the collateral object of the indebted party to the receivable party without
the indebted party's knowledge. From this background, researchers are interested in
conducting research with the title "Judicial Analysis in the Unlawful Transfer of
Collateral Objects of Land (Decision Study Number 26/PDT.G/2021/PN.MDN)." The
problem in this research is related to implementation. the collateral object of a plot of
land that was transferred unlawfully, legal protection for the debtor for the collateral
object of a plot of land that was transferred unlawfully, and legal analysis of the
unlawful transfer of the collateral object of a plot of land based on decision number
26/pdt.g/2021/PN .Mdn. These problems will be answered using normative juridical
research methods which are descriptive analytical in nature, with qualitative data
analysis. The results of this research show that there are several irregularities in the
implementation of the transfer of land ownership rights, where first the land is an
object of collateral, not an object of sale and purchase, the debtor does not know that
the land which is the object of collateral has changed ownership, of course what the
debtor does of course it is against the law. Legal protection for the debtor for the
collateral object of a plot of land that has been transferred unlawfully, namely by
filing a lawsuit to cancel the agreement for the transfer of the collateral object to the
District Court on the basis of a claim for an unlawful act committed by the debtor,
and also because of the Deed of Sale and Purchase. does not have binding legal
force. Legal analysis of the unlawful transfer of the collateral object of a plot of land
based on decision number 26/pdt.g/2021/PN.Mdn, the author is of the opinion that
what was decided by the panel of judges was correct, because of the actions of the
defendants, whether defendants I, II, III , and IV, caused the plaintiff to suffer losses.154 HalamanSkripsi Sarjan
Isolation of pyridine degrading bacteria from soils contaminated with petrochemical industry effluents in purba medinipur
No full textPyridine and its derivatives are of major concern as environmental pollutants due to their toxic nature. Bioremediation is considered to be an alternative process to clean up the environment polluted with heterocyclic pollutants including pyridine and its derivatives. Our primeval objectives were first to isolate the pyridine degrading bacteria from the petrochemical industry effluent enriched soil sample collected from effluent discharge site in Purba Medinipur, West Bengal and further to explore morphological, biochemical, molecular characteristics and the optimum conditions under which these strains can most efficiently breakdown pyridine. In this study, one new bacterial strain, Shewanella algae (designated as MM) capable of utilizing pyridine as a sole carbon source was isolated from the contaminated site and we have explored different research approaches alongwith 16S rDNA gene analysis method for unveiling this intended purpose. Furthermore, it can be used effectively for the treatment of pyridine bearing wastewater and as a possible inoculum in a biofilter treating pyridine-laden gas
Isolation of pyridine degrading bacteria from soils contaminated with petrochemical industry effluents in purba medinipur
No full textPyridine and its derivatives are of major concern as environmental pollutants due to their toxic nature. Bioremediation is considered to be an alternative process to clean up the environment polluted with heterocyclic pollutants including pyridine and its derivatives. Our primeval objectives were first to isolate the pyridine degrading bacteria from the petrochemical industry effluent enriched soil sample collected from effluent discharge site in Purba Medinipur, West Bengal and further to explore morphological, biochemical, molecular characteristics and the optimum conditions under which these strains can most efficiently breakdown pyridine. In this study, one new bacterial strain, Shewanella algae (designated as MM) capable of utilizing pyridine as a sole carbon source was isolated from the contaminated site and we have explored different research approaches alongwith 16S rDNA gene analysis method for unveiling this intended purpose. Furthermore, it can be used effectively for the treatment of pyridine bearing wastewater and as a possible inoculum in a biofilter treating pyridine-laden gas
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