100,649 research outputs found
Krizleri incelemede kullan lan nitel tercih modelleri: Türkiye için bir probit model uygulamas : (1988-2009)
No full textÇal mam zda ilk olarak nitel tercih modelleri olan logit ve probit modellere yer verilemektedir. Ampirik k s mda; 1988-2009 döneminde Türkiye de, makroekonomik de i kenlerin krizleri aç klay c l probit modelle incelenmektedir. Ayr ca de i kenlere ait marjinal etkiler hesaplanarak krizlerin bu etkilenmenin derecesine de bak lm t r. Probit modeli sonuçlar na göre, faiz oran ve ithalat de i kenlerinin istatistiksel olarak anlams z ç km t r. Buna kar l k, enflasyon, döviz kuru, i sizlik oran , gayri safi milli has la ve endüstriyel üretim endeksi de i kenleri anlaml ve önemli olarak elde edilmi tir.In our study, firstly we are giving place to logit and probit models which are qualitative choice models. In the empirical part, 1988-2009 period in Turkey, we analyze the explanatory of macroeconomic variables on the crises by using probit model. Additionally, by calculating the marginal effects, we examine the degree of influences on crises. According to the probit model results; interest rate and import variables were found statistically insignificant, whereas inflation, exchange rate, unemployment rate, gross national product and industrial product index variables were obtained significant and important
Calculation of three-dimensional compressible laminar and turbulent boundary layers. Calculation of three-dimensional compressible boundary layers on arbitrary wings
No full textA very general method for calculating compressible three-dimensional laminar and turbulent boundary layers on arbitrary wings is described. The method utilizes a nonorthogonal coordinate system for the boundary-layer calculations and includes a geometry package that represents the wing analytically. In the calculations all the geometric parameters of the coordinate system are accounted for. The Reynolds shear-stress terms are modeled by an eddy-viscosity formulation developed by Cebeci. The governing equations are solved by a very efficient two-point finite-difference method used earlier by Keller and Cebeci for two-dimensional flows and later by Cebeci for three-dimensional flows
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
Comparison of secretory acid proteinase, phospholipase activity, and slime production in candida parapsilosis complex strains isolated from blood cultures and other clinical samples
No full textAmaç: Yüksek mortalite ve morbidite nedeni olan hastane kaynakl kan ak m enfeksiyonlar nda Candida türleri en s k dört etkenden biridir. Candida parapsilosis, Candida albicans'tan daha az virülan olarak kabul edilmesine ra men, son yirmi y lda insidans nda en fazla art görülen Candida türü olmu tur. Çal mam zda kan ve di er klinik örneklerden izole edilen C. parapsilosis su lar n n salg sal asit proteinaz (Sap), fosfolipaz enzim aktivitelerinin ve slime üretiminin kar la t r lmas amaçlanm t r.Gereç ve Yöntem: On sekiz ayl k süreçte kan kültürleri ve di er klinik örneklerden izole edilen 28 C. parapsilosis su unun asit proteinaz aktivitesi süt tozu agaroz yöntemiyle, fosfolipaz aktivitesi yumurta sar l agar yöntemiyle, slime üretimi ise glukozlu s v sabouraud besiyeri ve glukozlu triptik soy broth kullan larak tüp adezyon yöntemi ile belirlendi.Bulgular: Çal ma izolatlar n n tümünde Sap aktivitesi belirlenemedi. Ancak kan ve kan d klinik izolatlar n Sap aktiviteleri aras nda istatistiksel olarak anlaml fark bulunmad . zolatlar n hiçbirinde fosfolipaz aktivitesi belirlenemedi. zolatlar n 23'ünde her iki besiyeriyle de slime üretimi görüldü. Yaln zca bir izolat her iki besiyeri ile de slime negatifti. Dört izolatta ise iki farkl besiyeri ile slime üretimi aç s ndan farkl sonuçlar elde edildi. Kan izolatlar ile di er klinik izolatlar n slime üretimleri aras nda istatistiksel olarak anlaml bir fark görülmedi.Sonuç: C. parapsilosis izolatlar nda Sap aktivitesi ve slime üretimi virülans faktörü olarak öne ç kmaktad r. Fosfolipaz aktivitesinin belirlenmesinde ba ka yöntemlerin kullan lmas n n yararl olabilece i dü ünülmektedirObjective: Candida species comprise one of the four most common agents in hospital-acquired bloodstream infections with high mortality and morbidity. Although C. parapsilosis is accepted as less virulent than C. albicans, it has been the Candida species with the highest increase in incidence within the last two decades. In our study, a comparison is made between the secretory acid proteinase (Sap), phospholipase enzyme activity and the slime production of C. parapsilosis strains isolated from blood with those isolated from other clinical samples. Material and Methods: Sap activity was determined by the milk powder agarose method, phospholipase activity by the egg-yolk agar method and slime production by the tube adhesion method using a liquid Sabouraud medium with glucose and tryptic soy broth with glucose of 28 C. parapsilosis strains isolated from blood cultures and other clinical samples during a period of eighteen months. Results: Sap activity was detected in all the study isolates; however, there was no statistically significant difference in Sap activity between the blood and non-blood clinical isolates. Phospholipase activity was not detected in any of the isolates. In 23 of the isolates, slime production was observed in both media, while only one isolate was slime negative in both culture media. In the remaining four isolates slime production results were different for the two different media. There was no statistically significant difference in slime production between the blood and other clinical isolates
Solutions manual and computer programs for physical and computational aspects of convective heat transfer
No full textThis book is designed to accompany Physical and Computational Aspects of Convective Heat Transfer by T Cebeci and P Bradshaw and contains solutions to the exercises and computer programs for the numerical methods contained in that book Physical and Computational Aspects of Convective Heat Transfer begins with a thorough discussion of the physical aspects of convective heat transfer and presents in some detail the partial differential equations governing the transport of thermal energy in various types of flows The book is intended for senior undergraduate and graduate students of aeronautical, chemical, civil and mechanical engineering It can also serve as a reference for the practitione
Role of implants in the treatment of diabetic macular edema: focus on the dexamethasone intravitreal implant
No full textZafer Cebeci, Nur KirDepartment of Ophthalmology, Istanbul Faculty of Medicine, Istanbul University, Capa, Istanbul, TurkeyAbstract: Diabetic macular edema (DME) is the leading cause of sight-threatening complication in diabetic patients, and several treatment modalities have been developed and evaluated to treat this pathology. Intravitreal agents, such as anti-vascular endothelial growth factors (anti-VEGF) or corticosteroids, have become more popular in recent years and are widely used for treating DME. Sustained release drugs appear to be mentioned more often nowadays for extending the period of intravitreal activity, and corticosteroids play a key role in inhibiting the inflammatory process in DME. A potent corticosteroid, dexamethasone (Ozurdex®), in the form of an intravitreal implant, has been approved for various ocular etiologies among which DME is also one. This review evaluates the role of implants in the treatment of DME, mainly focusing on the dexamethasone intravitreal implant.Keywords: diabetes mellitus, diabetic macular edema, vascular endothelial growth factor, dexamethasone, Iluvien, corticosteroi
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Pelevin’s Trinity in the novel “t”: author – protagonist – reader
No full textThe article attempts to interpret Pelevin's artistic strategy in the novel "T" by exploring its subject organization and addressing the key problems of the author, the protagonist, and the reader as they are seen by the researcher. The article analyzes the peculiarities of constructing the narrative reality in the novel "T", and goes on to discuss Pelevin's philosophic models of the development of the humankind, and the emergence of his new anthropology
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