238 research outputs found
Encyclopedia of Quality of Life and Well-being Research
No full textField Editor and Editorial Board Member.
Entries under Filomena Maggino's responsibilities:
- Conceptual design of indicators (author: F. Maggino),
- Indicator Development and Construction (author: F. Maggino),
- Data Representation (authors: F. Maggino & M. Trapani),
- Guttman Scale (author: F. Maggino),
- Indicator development and construction (author: F. Maggino),
- Multidimensional Analysis (authors: F. Maggino & M. Fattore),
- Multivariate Statistical Analysis (authors: F. Maggino & M. Fattore),
- Partially Ordered Set (author: M. Fattore),
- Questionnaire Design (author: W. Saris),
- Semantic Differential (author: F. Maggino),
- Subjective Indicators (author: A. Michalos),
- Subjective Weighting (author: K. Land),
- Systems of Indicators (author: H-H. Noll),
- Weighting Schemes (author: K. Land).
The Encyclopedia:
- represents the first comprehensive reference work on scientific and other scholarly research on the quality of life
- covers the subject of quality-of-life from a multi disciplinary perspective
- includes the behavioral and social sciences as well as health and healthcare
Encyclopedia's Keywords: Happiness - Health - Patient-reported outcomes research - Positive Psychology - Psychology - QOL - Quality of Life Research - Social Indicators - Sociology - Spirituality - Wealth - Welfare - Wellbeing
Encyclopedia's related subjects: Economics - Medicine - Psychology - Well-Bein
Erratum: Lack of immunity against rubella among Italian young adults. [BMC Infect Dis., 17, (2017) (199)] Doi: 10.1186/s12879-017-2295-y
No full textAfter publication of this article [1], the authors noted that the given names and family names of all authors had been inverted, and are therefore incorrect in the original article. In the original article, the author names appear as the following: Gallone Maria Serena, Gallone Maria Filomena, Larocca Angela Maria Vittoria, Germinario Cinzia and Tafuri Silvio. However, this is incorrect, and the author names should appear as per the below: Maria Serena Gallone, Maria Filomena Gallone, Angela Maria Vittoria Larocca, Cinzia Germinario, Silvio Tafuri. The author names have been corrected in the author list and the citation for this Erratum
[Poesia] Poema de Filomena Malva
No full textA poem by Filomena Malva About the author: Born in Luanda, on December 6, 1952. At the age of six months, she moved to Sá da Bandeira, now Lubango, where she completed her primary and secondary studies, beginning her studies at the Faculty of Letters of University of Luanda. At the Faculty of Letters of the University of Coimbra, she completed her degree in History, as well as his postgraduate degree in "Portuguese expansion in the Atlantic world". She pursued her professional activity as a History teacher. Regarding scientific publications, In 1996, the unpublished work O retábulo-mor da capela de Nossa Senhora da Paz da Constantina. In 2015, she published the lyric poetry work entitled Aspirar a polpa do absoluto, with the review of Carmen Lucia Tindó Secco, whose edition is sold out. She participated in the blog MyAngola / MinhaAngola with poetic words and comments and, yet in the scope of the blog, was invited to write a foreword to the poetic works Mentes perversas e outras conversas, by Ana Paula Lavado, and Silêncios de outono, by Graça Arrimar, respectively in Porto and in Coimbra.Un poema de Filomena Malva Sobre la autora: Nacida en Luanda el 6 de diciembre de 1952. Con 6 meses de edad, se trasladó a Sá da Bandeira, actual Lubango, donde completó sus estudios de primaria y secundaria, a partir de la educación superior en la Facultad de Artes, Universidad de Luanda. En la Facultad de Artes de la Universidad de Coimbra concluyó un grado en Historia, así como estudios de postgrado en “La expansión portuguesa en el mundo atlántico”. Ejerció su carrera profesional como maestra de Historia. No lo que se refiere a las publicaciones científicas, se publicó, en 1996, la obra inédita O retábulo-mor da capela de Nossa Senhora da Paz Constantina. Em 2015 publicó el trabajo de la lírica titulada Aspirar à Polpa de Tudo -- con la opinión de Carmen Lucia Tindó Secco --, cuya edición está agotada. Participado en el proyecto MyAngola/MinhaAngola blog con palabras poéticas y comentarios y, en virtud de que, fue invitada a presentar la obra poética Mentes perversas e outras conversações de Ana Paula Lavado, y Silêncios de outono, de Graça Arrimar, respectivamente en Porto y Coimbra.Poema de Filomena Malva. Sobre a autora: Nasceu em Luanda, a 6 de dezembro de 1952. Com 6 meses de idade, foi viver para Sá da Bandeira, atual Lubango, onde concluiu os seus estudos primários e liceais, iniciando o ensino superior na Faculdade de Letras da Universidade de Luanda. Na Faculdade de Letras da Universidade de Coimbra concluiu a licenciatura em História, assim como a pós-graduação em “A expansão portuguesa no mundo atlântico”.Exerceu a sua atividade profissional enquanto docente de História.No que concerne a publicações científicas, foi publicada, em 1996, a obra inédita O retábulo-mor da capela de Nossa Senhora da Paz da Constantina. Em 2015 publicou a obra de poesia lírica intitulada Aspirar a polpa do absoluto, com parecer de Carmen Lucia Tindó Secco, cuja edição está esgotada. Participou, no blogue do projeto MyAngola/MinhaAngola, com palavras poéticas e comentários e, no âmbito do mesmo, foi convidada para apresentar as obras poéticas Mentes perversas e outras conversas, de Ana Paula Lavado, e Silêncios de outono, de Graça Arrimar, respectivamente no Porto e em Coimbra
Molecular mechanisms governing microRNA-125a expression in human hepatocellular carcinoma cells
No full textMicroRNA-125a-5p (miR-125a) is a vertebrate homolog of lin-4, the first discovered microRNA, and plays a fundamental role in embryo development by downregulating Lin-28 protein. MiR-125a is also expressed in differentiated cells where it generally acts as an antiproliferative factor by targeting membrane receptors or intracellular transductors of mitogenic signals. MiR-125a expression is downregulated in several tumors, including hepatocellular carcinoma (HCC) where it targets sirtuin-7, matrix metalloproteinase-11, VEGF-A, Zbtb7a, and c-Raf. In this study, we have isolated the transcription promoter of human miR-125a and characterized its activity in HCC cells. It is a TATA-less Pol II promoter provided with an initiator element and a downstream promoter element, located 3939 bp upstream the genomic sequence of the miRNA. The activity of the promoter is increased by the transcription factor NF-kB, a master regulator of inflammatory response, and miR-125a itself was found to strengthen this activation through inhibition of TNFAIP3, a negative regulator of NF-kB. This finding contributes to explain the increased levels of miR-125a observed in the liver of patients with chronic hepatitis B.MicroRNA-125a-5p (miR-125a) is a vertebrate homolog of lin-4, the first discovered microRNA, and plays a fundamental role in embryo development by downregulating Lin-28 protein. MiR-125a is also expressed in differentiated cells where it generally acts as an antiproliferative factor by targeting membrane receptors or intracellular transductors of mitogenic signals. MiR-125a expression is downregulated in several tumors, including hepatocellular carcinoma (HCC) where it targets sirtuin-7, matrix metalloproteinase-11, VEGF-A, Zbtb7a, and c-Raf. In this study, we have isolated the transcription promoter of human miR-125a and characterized its activity in HCC cells. It is a TATA-less Pol II promoter provided with an initiator element and a downstream promoter element, located 3939 bp upstream the genomic sequence of the miRNA. The activity of the promoter is increased by the transcription factor NF-kB, a master regulator of inflammatory response, and miR-125a itself was found to strengthen this activation through inhibition of TNFAIP3, a negative regulator of NF-kB. This finding contributes to explain the increased levels of miR-125a observed in the liver of patients with chronic hepatitis B
The paratextual framework of «La Filomena»: editorial model and literary model
No full textEl análisis de dedicatorias de La Filomena(1621) sugiere que fueron compuestas en base a una poética paratextual cuya función era mostrar una imagen ideal del autor Lope de Vega.The analysis of dedications in La Filomena(1621) suggests that they were composed on the basis of a paratextual poetic whose function was to show an ideal image of the author Lope de Vega
Patrick Modiano (2014) Filomena Firmeza. São Paulo: Cosac & Naify
No full textAnalysis of one of the children\u27s literary issues where the author Patrick Modiana addresses the issue of lying. A story of a dance teacher (Filomena Firmeza), narrated in the first person, where her childhood in New York is recounted and consequently her present is talked about with a visit to her parents. The author addresses family ties in his work which makes the book interesting for anyone to read and was considered by many as one of his best books.Análise de uma das questões literárias infanto-juvenil onde o autor Patrick Modiana aborda a questão da mentira. História de uma professora de dança (Filomena Firmeza), narrada na primeira pessoa, onde se relata a sua infância em Nova York e consequentemente se fala do seu presente com a visita aos seus pais. O autor aborda os laços familiares na sua obra o que torna o livro interessante para qualquer um ler, considerado por muitos como um dos seus melhores livros
Human MiR-544a Modulates SELK Expression in Hepatocarcinoma Cell Lines.
No full textHepatocellular carcinoma (HCC) is a multi-factorial cancer with a very poor prognosis; therefore, there are several investigations aimed at the comprehension of the molecular mechanisms leading to development and progression of HCC and at the definition of new therapeutic strategies. We have recently evaluated the expression of selenoproteins in HCC cell lines in comparison with normal hepatocytes. Recent results have shown that some of them are down- and others up-regulated, including the selenoprotein K (SELK), whose expression was also induced by sodium selenite treatment on cells. However, so far very few studies have been dedicated to a possible effect of microRNAs on the expression of selenoproteins and their implication in HCC. In this study, the analysis of SELK 3'UTR by bioinformatics tools led to the identification of eight sites potentially targeted by human microRNAs. They were then subjected to a validation test based on luciferase reporter constructs transfected in HCC cell lines. In this functional screening, miR-544a was able to interact with SELK 3'UTR suppressing the reporter activity. Transfection of a miR-544a mimic or inhibitor was then shown to decrease or increase, respectively, the translation of the endogenous SELK mRNA. Intriguingly, miR-544a expression was found to be modulated by selenium treatment, suggesting a possible role in SELK induction by selenium
Certi pomeriggi non passano mai:Some Afternoons Never Seem to End
No full textCerti pomeriggi non passano mai by Mario Fortunato is a short and engaging theatre monologue that analyzes the tension created by waiting for a beloved who is late for an appointment. The wait stretches for hours and creates controversial emotions and anxiety ironically described by the author, with hilarious moments that go from drama to comedy to the surreal, in a sort of ‘one man’ Waiting for Godot. The text was freely adapted and performed in Italian, with some parts in German and English. Theatralia is an international collective of performers and artists who explore texts through physical theatre, live art & music, inventive digital art, and audience participation that was founded by Filomena Campus in 2003. Since 2006 Theatralia’s productions have been sponsored by the Arts Council England. Their much acclaimed production Misterioso. A Journey into the Silence of Thelonious Monk, written by Stefano Benni, was presented at London Riverside Studios and at the Edinburgh Festival.
Filomena Campus is a theatre director and a Jazz musician. Productions include Not in My Name inspired by The Living Theatre and U238 by Marco Paolini. Filomena has also worked as university lecturer in London. For more details see: www.filomenacampus.com Mario Fortunato is an author, literary critic, and the former Director of the Italian Cultural Institute in London. His publications include: Luoghi naturali, L’arte di perdere peso, I giorni innocenti della Guerra, Allegra Street, Il viaggio a Paros, and L’Italia degli altri. He regularly writes for the Italian news magazine L’Espresso
Un riparo per l’antico. Progetto di una copertura archeologica a Piazza Bellini Napoli, 2023
No full textLa città è fatta di strata spesso invisibili e poco intellegibili, soprattutto quando non vi è un’architettura chiamata a renderli manifesti. È il caso delle mura greche del V-IV secolo a.C. di Piazza Bellini a Napoli che – rinvenute per caso nel 1954 e lasciate scoperte e inaccessibili, sottoposte e recintate – non riescono a stabilire alcun chiaro rapporto con la città “di sopra” che, a sua volta, si organizza secondo un ordine completamente differente.
Il progetto, esito di un workshop-tirocinio con giovani studentesse, si pone l’obiettivo di risistemare l’intera piazza Bellini, posta sul limite del centro greco-romano della città, a partire dalla necessità di proteggere, ma anche e forse soprattutto di ‘rivelare’, le mura della cui presenza si rischia di non accorgersi neppure per l’assenza di un disegno sintetico che vede oggi lo spazio sgombrato rappresentato nel Settecento da Antonio Joli inutilmente affollato di alberature, monumenti – innanzitutto quello al musicista catanese Vincenzo Bellini formatosi a Napoli nel Collegio di Musica di San Sebastiano, oggi Conservatorio di San Pietro a Majella, adiacente la piazza – dehors e arredo urbano.
Razionalizzato lo scavo, un alto riparo dorato rende manifesta la giacitura ruotata delle mura, nella foratura e nel disegno della pavimentazione, e trova il suo contrappunto in un portico che ordina gli spazi all’aperto di bar, caffe letterari e ristoranti che “abitano” la piazza, reimmettendo in tal modo le rovine nella dinamica urbana e costruendo un doppio registro seguendo il quale la città rende manifesta e non finge o dissimula le radici millenarie dalle quali proviene. La copertura in acciaio dipinto di giallo oro – di “giallo Napoli” – vuole essere un riparo per l’antico che, nel riprendere allineamenti, altezze e scansioni dei fronti degli edifici esistenti, introduce una nuova singolarità urbana, chiamata a caratterizzare lo spazio pubblico, e, nell’affondare nelle profondità ctonie tufacee, al tempo stesso, si libera come una grande pergola a segnalare le antiche vestigia che ombreggia e protegge. Un abri souverain, come nella nota definizione di Auguste Perret, che nella esattezza delle proporzioni – un quadrato in pianta, due quadrati in alzato – e nella essenzialità logica della costruzione tettonica – quattro coppie di piedritti a sorreggere due travi mediane a sezione variabile che a loro volta sorreggono una graticcio pergolato – ha il compito di mettere in opera e in scæna la grandezza dell’antico senza mimetismi ma neppure irrisioni perché, seguendo il noto aforisma di Karl Kraus, Ursprung ist das Ziel
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