3,382 research outputs found
Giovanni Battista Aleotti da Argenta (1546-1636) : scienza ed architettura delle acque nel Ducato di Ferrara fra 16. e 17. sec.
No full textCesare Scurati, maestro e interprete della media education. Intervista a Angela Bonomi Castelli
No full textL'autore propone e commenta una intervista ad Angela Bonomi Castelli, referente dell'Associazione italiana per l'educazione ai media e alla comunicazione e profonda conoscitrice della figura di uno dei fondatori della stessa Associazione: Cesare Scurat
Lettera a D. Benedetto Castelli 21 dicembre 1613
No full textCritical edition of the newly discovered autograph of Galileo's Letter to B. Castelli, the first of Galileo's Copernican Letters devoted to the relationship between natural philosophy and theology, astronomy and the Holy Scriptures
A procedure for the definition of a patient-specific kinematic model of the knee joint: an in-vivo validation
No full textThe capability to model human joint motion is a fundamental step towards the definition of effective treatments and medical devices, with an increasing request to adapt the devised models to the specificity of each subject. We present an approach for the definition of subject-specific models of the knee natural motion. The approach is the result of a combination of two different techniques and exploits the advantages of both. It relays upon non invasive measurements that can be performed in vivo, based on which a kinematic model of the natural motion is built, suitable to be extended to the definition of static and dynamic models. Comparison of the model outcomes with in-vivo measurements performed on one subject shows promising results supporting the proposed approach
Use of the principle of virtual work reciprocity to explain the human joint motion: application to the knee
No full textThe study of natural motion of human joints, i.e. the unresisted motion that the articulations exhibits in the absence of external loads, provides insights into their physiology. The natural motion represents the baseline condition upon which deformations of passive structures (i.e., ligaments and cartilage) take place when loads are applied. During natural motion, the strain energy density stored within ligaments and cartilage is minimized, reducing the chance of microdamage occurrences and the corresponding metabolic cost for tissue repairing. The study of the natural motion is thus fundamental to understand the joint physiology. In this work, the geometrical arrangement of the constraints necessary for the joint natural motion is theoretically derived from the application of the principle of virtual work. The implication of this general approach will be derived and experimentally verified for the knee
Lettera a D. Benedetto Castelli 21 dicembre 1613
No full textCritical edition of the newly discovered autograph of Galileo's Letter to B. Castelli, the first of Galileo's Copernican Letters devoted to the relationship between natural philosophy and theology, astronomy and the Holy Scriptures
Lettera a D. Benedetto Castelli 21 dicembre 1613
No full textCritical edition of the newly discovered autograph of Galileo's Letter to B. Castelli, the first of Galileo's Copernican Letters devoted to the relationship between natural philosophy and theology, astronomy and the Holy Scriptures
Novel evolutionary insights on the interactions of the Holosporales (Alphaproteobacteria) with eukaryotic hosts from comparative genomics
No full textHolosporales are an alphaproteobacterial order engaging in obligate and complex associations with eukaryotes, in particular protists. The functional and evolutionary features of those interactions are still largely undisclosed. Here, we sequenced the genomes of two members of the species Bealeia paramacronuclearis (Holosporales, Holosporaceae) intracellularly associated with the ciliate protist Paramecium, which resulted in high correspondence. Consistent with the short-branched early-divergent phylogenetic position, Bealeia presents a larger functional repertoire than other Holosporaceae, comparable to those of other Holosporales families, particularly for energy metabolism and motility. Our analyses indicate that different Holosporales likely experienced at least partly autonomous genome reduction and adaptation to host interactions, for example regarding dependence on host biotin driven by multiple independent horizontal acquisitions of transporters. Among Alphaproteobacteria, this is reminiscent of the convergently evolved Rickettsiales, which however appear more diverse, possibly due to a probably more ancient origin. We identified in Bealeia and other Holosporales the plasmid-encoded putative genetic determinants of R-bodies, which may be involved in a killer trait towards symbiont-free hosts. While it is not clear whether these genes are ancestral or recently horizontally acquired, an intriguing and peculiar role of R-bodies is suggested in the evolution of the interactions of multiple Holosporales with their hosts
Michele Taruffo: el magisterio y la obra ejemplares del genial procesalista «todoterreno»
No full textThe author reflects on Michele Taruffo’s extraordinarily important contribution to the renewal of both conventional procedural law scholarship and the theoretical background of law-court professionals. Taruffo’s contribution was achieved by means of introducing to mainstream culture in those circles the necessary knowledge of the underlying epistemic dimension, which was traditionally suppressed by the strictly legal one.El autor discurre acerca de la importantísima contribución de Michele Taruffo a la renovación del procesalismo convencional y del bagaje teórico de los profesionales de la jurisdicción, mediante la incorporación a la cultura dominante en tales medios del imprescindible conocimiento de la dimensión epistémica subyacente y tradicionalmente sofocada por la propiamente jurídica
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