1,721,063 research outputs found
Video-Assisted Thoracoscopic Sympathicotomies for the Treatment of Palmar and Axillary Hyperhidrosis
Frontal Endoscopic Myotomies for Chronic Headache.
Recent insights into the pathogenesis of migraine headache
substantiate a neuronal hyperexcitability and inflammation
involving compressed peripheral craniofacial nerves, and these
trigger points can be eliminated by surgery. The aim of this study
was to describe a modified, innovative, minimally invasive endoscopic
technique to perform selective myotomies of corrugator
supercilii, depressor supercilii, and procerus muscles, which turned out to be an effective therapy for migraine and tension-type
headaches.
Forty-three patients (18–75 years) who experienced 15 or more
frontal migraine headaches without aura, tension-type headaches, or
new daily persistent headaches each month were enrolled in the
study between 2011 and 2013. Of 43 patients, 15 were followed for
2 years. Fourteen patients (93.3%) reported a positive response to
the surgery: 5 (33.3%) observed complete elimination, 9 (60%)
experienced significant improvement (at least 50% reduction in
intensity or frequency), and 1 patient (6.6%) did not notice any
change in their headaches. A statistically significant difference was
found between our protocol compared with currently performed,
more invasive technique (odds ratio, 1.9; 95% confidence interval,
1.151–3.13).
According to our data, the modified endoscopic procedure leads
to better results, compared to previous techniques, together with
eliminating the need for general anesthesia, reducing the invasiveness
of the procedure and the number of postoperative scars
Scalp Surgery: Quantitative Analysis of Follicular Unit Growth
Background: Over the years, different kinds of hair transplantation have
been compared in an attempt to overcome male pattern alopecia and, at
the same time, maximize both the survival and growth rate of grafted hair.
In this study, we have assessed the survival and growth rate of follicular
units (FU) in an in vitro model, as compared with that of conventional hair
micrografts, to experimentally evaluate and elaborate on the differences
between these 2 approaches in hair transplantation procedures.
Methods: Group A (control; n = 100 follicles) was composed of hair micrografts,
whereas FUs were assigned to Group B (experimental; n = 100
follicles, n = 35 FUs). Each group was cultured for a period of 10 days; the
total stretch of follicles was measured soon after the harvest and 10 days
later. The Kruskal-Wallis one-way analysis of variance on ranks test was used
to perform statistical analysis.
Results: The growth rate of follicles from Group A (mean 10-day shaft
growth rate = 0.30 mm) proved to be statistically different compared with
that of Group B (mean 10-day shaft growth rate = 0.23 mm). Conversely,
our data did not show any significant difference between the survival rate
of hair grafts from these 2 groups.
Conclusions: Our data highlighted a reduced FU shaft growth compared
with that of hair micrografts, corroborating, to a certain extent, the
hypothesis that a significant amount of adipose tissue surrounding the
follicle
included in the graft may result in an inadequate nourishment
supply to follicular cells
Experimental advances in hair restoration surgery
When performing hair transplantation procedures, it is of the foremost importance to try to obtain the maximum survival rate possible of transplanted micrografts. We present an in-vitro model to test hair graft survival and growth after various surgical procedures.
Material and Methods:
A total of 1020 human anagen hair follicles was obtained from 50 male patients and thus randomly assigned to one of the following groups: Group A (control), conventional micrografts cultured as dissected; Group B (experimental), conventional micrografts preserved (before culture) for five hours in a storage medium; Group C (control;), conventional micrografts preserved (before culture) for five hours in saline at room temperature; Group D (experimental), conventional micrografts preserved (before culture) for 5 hours at1°C; Group E (experimental), “plucked” hair follicles; Group F (experimental), follicular units; Group G (experimental) skeletonized micrografts. Hair follicles from all the groups were then cultured for 10 days.
Results:
A statistically significant difference was found between the survival rate of follicles from Group B (98%) and Group A (87%), as well as between the growth rate of Group E (mean 10-day shaft growth =2.36 mm) and Group F (mean 10-day shaft growth =2.23 mm) as compared to Group A. No statistically significant differences were found between the growth rate of follicles from Group C and Group D or from Group G and Group A.
Conclusion:
According to our data, the described method is, in our opinion, an useful adjunct in order to quantitatively evaluate the effects of various procedures in the field of hair transplantation surgery
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Editorial - Non AIDS-defining malignancies: a new epidemic in HIV-infected population for the upcoming decades?
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