30,133 research outputs found

    Intrapartum Ultrasound Parameters (Ultrasonographic Semeiotics)

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    During the last decade, the value of ultrasounds has been confirmed for the diagnosis of feto-maternal disease and extended to the intrapartum examination. Ultrasound in labor can improve the assessment of fetal head position during labor [1]. The ultrasound examination can be performed during both the physiologic and dystocic delivery; it is a reliable technique, able to predict the possible complications of labor, thus allowing to choice the best management promptly. Several studies confirmed the reliability and utility of ultra- sounds in the delivery ward, where it is able to implement the routine clinical assessment. The manual obstetric evaluation is not replaced in the assessment of feto-maternal relation- ship and diameters, such as the external abdominal palpation according with the four Leopold’s maneuvers, the “in vivo” assessment of the obstetric pelvis to evaluate the competence of the birth canal and the pelvic diameters (Fig. 11.1). Ultrasounds offer the option of a complementary exami- nation, able to improve the monitoring of first and second stage of labor. Rayburn et al. demonstrated the ultrasounds’ better accuracy in the assessment of fetal head position if compared to the digital obstetric examination [2], affected by a high rate error in the identification of the fetal head station, especially in case of head remodelling and presence of caput succedaneum. Kilpatrick observed that the accuracy of vagi- nal examination can be affected by the cervical shortening that compromises the palpation of the fetal presented part and ischial spines; contrarily, this is not happening with intrapartum ultrasound [3]. The recent literature refers to the classical partogram as poorly reliable, affected by the subjectivity of obstetric assessment, and supports the necessity of a more objective evaluation. An objective and documented examination is essential nowadays, especially at the light of a growing med- icolegal issue: ultrasounds allow to assess objectively the A. Vimercati (*) · F. M. Crupano · M. Calabretti · E. Cicinelli 2nd Unit of Obstetrics and Gynaecology, Department of Biomedical and Human Oncological Science, University of Bari, Bari, Italy ongoing labor and to store pictures of fetal position and pos- sible dangerous situations, so supporting the clinician choice and obstetric management [4]. All the above observations give reason of the increasing use of ultrasounds in the delivery ward; nevertheless it is important to keep in mind that also the ultrasound assess- ment is subjective, and despite its potentiality, it cannot replace the clinical assessment that should always be per- formed when approaching the patient, before every instru- mental examination. The knowledge of specific ultrasound reference points allows to detail precisely the relationship between the fetal head and maternal pelvis and to follow the progression of labor, quickly detecting possible critical issues [5]. Several experts have been looking for similar parameters, so describ- ing various pelvic and ultrasound indexes; all of them are assessed by the translabial scan (Fig. 11.2), and the most sig- nificant described in literature are the following: • Angle of progression (AoP) • Head progression distance (PD) • Fetal head direction • Head-perineum distance • Head-symphysis distance (HSD) • Midline angle (MLA) • Pubic arch angle (PAA

    Maria Bersani

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    La voce illustra la biografia e l'apporto letterario dato da Maria Bersani alla letteratura per l'infanziaThe headword explains the biography and the contribution of the author Maria Bersani to the children's literatur

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Erratum: Lack of immunity against rubella among Italian young adults. [BMC Infect Dis., 17, (2017) (199)] Doi: 10.1186/s12879-017-2295-y

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    After publication of this article [1], the authors noted that the given names and family names of all authors had been inverted, and are therefore incorrect in the original article. In the original article, the author names appear as the following: Gallone Maria Serena, Gallone Maria Filomena, Larocca Angela Maria Vittoria, Germinario Cinzia and Tafuri Silvio. However, this is incorrect, and the author names should appear as per the below: Maria Serena Gallone, Maria Filomena Gallone, Angela Maria Vittoria Larocca, Cinzia Germinario, Silvio Tafuri. The author names have been corrected in the author list and the citation for this Erratum

    Cytotoxicity profiles and neuroprotective properties of the novel ifenprodil analogues as sigma ligands

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    Neurodegeneration is a slow and progressive loss of neuronal cells or their function in specific regions of the brain or in the peripheral system. Among several causes responsible for the most common neurodegenerative diseases (NDDs), cholinergic/dopaminergic pathways, but also some endogenous receptors, are often involved. In this context, sigma 1 receptor (S1R) modulators can be used as neuroprotective and antiamnesic agents. Herein, we describe the identification of novel S1R ligands endowed with antioxidant properties, potentially useful as neuroprotective agents. We also computationally assessed how the most promising compounds might interact with the S1R protein’s binding sites. The in silico predicted ADME properties suggested that they could be able to cross the brain-blood-barrier (BBB), and to reach the targets. Finally, the observation that at least two novel ifenprodil analogues (5d and 5i) induce an increase of the mRNA levels of the antioxidant NRF2 and SOD1 genes in SH-SY5Y cells suggests that they might be effective agents for protecting neurons against oxidative damage

    Imagens de Otto Maria Carpeaux: esboço de biografia

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    Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas, Programa de Pós-Graduação em História, Florianópolis, 2015.Este esboço de biografia procura citar algumas imagens de Otto Maria Carpeaux: construções biográficas de naturezas múltiplas, elaboradas em contextos, por atores e sob condições igualmente díspares. Está constituído a partir de uma visão crítica da História, o que permite que ?outras imagens?, fragmentárias e não monumentais, também tenham espaço. Em diálogo com o princípio da montagem, este esboço apresenta-se em duas partes. Na primeira, Imagens possíveis, estão citadas as imagens elaboradas em vida e post mortem acerca do austríaco-brasileiro que nasceu em Viena em 1900, se exilou no Brasil em 1939 e morreu no Rio de Janeiro, em 1978. Na segunda, Montagens possíveis, apresentam-se duas possibilidades de exercício biográfico: pela leitura alegórica do documentário O velho e o Novo (Otto Maria Carpeaux), entendido como instrumento de intervenção no contexto ditatorial brasileiro e de uma reelaboração biográfica concernentes às suas experiências europeias; e pelo Caderno de imagens críticas, registro dos encontros em Carpeaux pelo meio de imagens críticas produzidas a partir da cesura do presente.Abstract : This biographical sketch attempts to quote some images of Otto Maria Carpeaux: various types of biographical constructions, carried out in different contexts by disparate authors under conditions just as distinct. It stems from a critical view of history, allowing for ?other images? fragmented and non-monumental ? to share the space.In dialogue with the montage principle, this sketch has two parts. The first, Possible Images, quotes the images produced during and after the life of the Austrian-Brazilian, who was born in Vienna in 1900, went to Brazil in exile in 1939 and died in Rio de Janeiro in 1978. The second part, Possible Montages, presents two possibilities of a biographical exercise: through the allegorical reading of documentary O Velho e o Novo (Otto Maria Carpeaux), understood as an instrument of intervention in the Brazilian dictatorship context and as a biographical retelling of the author?s European experiences; and through my Scrapbook of Critical Images, a record of the encounters in Carpeaux through critical images produced from the caesura of the present

    Maria José ao encontro de Tchekov

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    “A Carta da Corcunda para o Serralheiro” (“Letter from the Hunchback Girl to the Metalworker”), signed by Maria José, was first performed in a theatre show in 1988 (by actress-director Maria do Céu Guerra), two years before the typescript was published in book form for the first time by Teresa Rita Lopes. The evidence upon which this article is built is that it was the theatre that revealed the dramatic destination of this singular epistle of the only female heteronym that Fernando Pessoa invented, which was also the last heteronym to be created by the author. The dramatic construction of Maria José can be approximated to the character-building strategies in Anton Chekhov’s realist dramaturgy, in a way that differs from Pessoa’s other dramaturgical experiences. The analysis of Chekhov’s ascendancy over Stanislavski’s research, as well as the importance of Schopenhauer’s conception of the tragicomic, which is simultaneously projected onto Chekhov’s theatre and Maria José’s profile, are favourable lines of reading for this rapprochement between Pessoa and the Russian fiction writer and playwright. Pessoa’s readings of Chekhov’s texts (such as the play Uncle Vania and the short story “Vanka”) provide relevant data for assessing the magnitude of this encounter.“A Carta da Corcunda para o Serralheiro”, assinada por Maria José, começou por ser difundida num espectáculo de teatro em 1988 (pela actriz-encenadora Maria do Céu Guerra) dois anos antes de o dactiloscrito se ver publicado em livro, pela primeira vez, por Teresa Rita Lopes. Parte-se da evidência de ter sido o teatro a revelar a destinação dramática da epístola singular do único heterónimo mulher que Fernando Pessoa inventou, que terá sido também o último a ser criado pelo autor. A construção dramática de Maria José pode ser aproximada às estratégias de construção de personagem na dramaturgia realista de Anton Tchekov, de um modo que se distingue de outras experiências dramatúrgicas de Pessoa. A análise do ascendente de Tchekov sobre as pesquisas de Stanislavski, bem como a importância da concepção de tragicómico em Schopenhauer, que se projecta em simultâneo sobre o teatro de Tchekov e sobre o perfil de Maria José, são linhas de leitura propícias para esta aproximação entre Pessoa e o ficcionista e dramaturgo russo. As leituras de textos de Tchekov por parte de Pessoa (como o caso da peça Tio Vânia e o conto “Vanka”) fornecem dados relevantes para avaliar a magnitude deste encontro
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