103,647 research outputs found
A canção popular "O ciúme" de Caetano Veloso
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-Graduação em Literatura.Este trabalho tem como objetivo investigar a maneira como os elementos que constituem a canção popular se articulam. A canção escolhida para a pesquisa é "O ciúme" de Caetano Veloso. Relações entre melodia e letra; relações entre harmonia tonal e presença de harmonia modal; características da obra de Caetano Veloso como presença de escalas modais e relações com outras canções; conceito de performance e arranjo como fundamentais para a construção da canção são abordados ao longo desse trabalho
Escola Nova, Escola Normal Caetano de Campos e o ensino de matemática na década de 1940
No full textO original desta publicação encontra-se depositado na Biblioteca da Universidade Federal de São Paulo, Escola de Filosofia, Letras e Ciências Humanas, 90f + anexos (CD-ROM).As primeiras décadas do século XX foram marcadas por uma nova vaga pedagógica entre os educadores brasileiros, conhecida como Escola Nova, cuja proposta era a de renovar o ensino. Simultaneamente, na década de 1940, uma série de mudanças ocorrem na estrutura do Curso Normal Paulista. Esta pesquisa busca compreender em que medida as apropriações desse movimento e as mudanças na formação de professores alteraram o ensino da matemática na Escola Normal Caetano de Campos, mais especificamente na disciplina de Metodologia e Prática do Ensino Primário, responsável pela formação pedagógica dos futuros professores. Nossas análises foram sustentadas pelos estudos da chamada História Cultural, dos quais destacamos o ferramental elaborado por Michel de Certeau e Roger Chartier. As fontes privilegiadas na investigação são avaliações finais realizadas pelos alunos, cotejadas com leis, livros, revistas e textos de autores que circularam no período estudado. Essas avaliações indicam a presença marcante dos planos globalizados como instrumento de avaliação, os quais eram produzidos a partir de um tema retirado de um recorte de jornal. Em relação ao ensino de matemática, evidenciou-se uma mudança nas finalidades da disciplina presente nessas avaliações, que passou a atender a realidade almejada pelos planos globalizados, em vez de seus conteúdos e habilidades próprios. As mudanças estruturais no Curso Normal Paulista não são perceptíveis no ensino de matemática na disciplina de Metodologia e Prática do Ensino Primário na década de 1940
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Pelevin’s Trinity in the novel “t”: author – protagonist – reader
No full textThe article attempts to interpret Pelevin's artistic strategy in the novel "T" by exploring its subject organization and addressing the key problems of the author, the protagonist, and the reader as they are seen by the researcher. The article analyzes the peculiarities of constructing the narrative reality in the novel "T", and goes on to discuss Pelevin's philosophic models of the development of the humankind, and the emergence of his new anthropology
The natural history of biocatalytic mechanisms
No full textJBOM and NN thank the Scottish Universities Life Science Alliance (SULSA) http://www.sulsa.ac.uk/ and Scottish Funding Council (SFC) http://www.sfc.ac.uk/ for financial support. JBOM thanks the Biotechnology and Biological Sciences Research Council (BBSRC) http://www.bbsrc.ac.uk/ for financial support through grant BB/I00596X/1 and GCA the National Science Foundation (OISE-1132791) http://www.nsf.gov/ and the United States Department of Agriculture (ILLU-802-909 and ILLU-483-625) http://www.csrees.usda.gov/ for financial support. EaStCHEM http://www.eastchem.ac.uk/ provided access to the ECRF computing facility.Phylogenomic analysis of the occurrence and abundance of protein domains in proteomes has recently showed that the α/β architecture is probably the oldest fold design. This holds important implications for the origins of biochemistry. Here we explore structure-function relationships addressing the use of chemical mechanisms by ancestral enzymes. We test the hypothesis that the oldest folds used the most mechanisms. We start by tracing biocatalytic mechanisms operating in metabolic enzymes along a phylogenetic timeline of the first appearance of homologous superfamilies of protein domain structures from CATH. A total of 335 enzyme reactions were retrieved from MACiE and were mapped over fold age. We define a mechanistic step type as one of the 51 mechanistic annotations given in MACiE, and each step of each of the 335 mechanisms was described using one or more of these annotations. We find that the first two folds, the P-loop containing nucleotide triphosphate hydrolase and the NAD(P)-binding Rossmann-like homologous superfamilies, were α/β architectures responsible for introducing 35% (18/51) of the known mechanistic step types. We find that these two oldest structures in the phylogenomic analysis of protein domains introduced many mechanistic step types that were later combinatorially spread in catalytic history. The most common mechanistic step types included fundamental building blocks of enzyme chemistry: “Proton transfer,” “Bimolecular nucleophilic addition,” “Bimolecular nucleophilic substitution,” and “Unimolecular elimination by the conjugate base.” They were associated with the most ancestral fold structure typical of P-loop containing nucleotide triphosphate hydrolases. Over half of the mechanistic step types were introduced in the evolutionary timeline before the appearance of structures specific to diversified organisms, during a period of architectural diversification. The other half unfolded gradually after organismal diversification and during a period that spanned ~2 billion years of evolutionary history.Peer reviewe
Measuring industry-science links through inventor-author relations: A profiling method
No full textIn this pilot study we examine the performance of text-based profiling in recovering a set of validated inventor-author links. In a first step we match patents and publications solely based on their similarity in content. Next, we compare inventor and author names on the highest ranked matches for the occurrence of name matches. Finally, we compare these candidate matches with the names listed in a validated set of inventor-author names. Our text-based profile methodology performs significantly better than a random matching of patents and publications, suggesting that text-based profiling is a valuable complementary tool to the name searches used in previous studies.innovation; industry-science links; text-based profiling;
Basin-scale contributions of Cr, Ni and Co from Ortegal Complex to the surrounding coastal environment (SW Europe).
No full textPrego, R., Caetano, M., Ospina-Alvarez, N., Raimundo, J., & Vale, C. (2014). Basin-scale contributions of Cr, Ni and Co from Ortegal Complex to the surrounding coastal environment (SW Europe). Science of the Total Environment, 468-469, 1–10. Retrieved from http://dx.doi.org/10.1016/j.scitotenv.2013.08.03
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