1,721,000 research outputs found
Clinical and endocrine effects of ovulation induction with FSH and HCG supplementation in low responders in the mid-follicular phase
No full textPremature elevation of progesterone and reproductive effectivness in medically assisted reproduction
No full textMassive ascites and hydrothorax after leuprolide acetate administration in a down-regulated woman undergoing assisted reproduction
No full textObjective: To present an atypical case of massive ascites and hydrothorax after leuprolide acetate administration in
a down-regulated woman undergoing assisted reproduction.
Design: Case report.
Setting: Centre for Reproductive Medicine, Department of Obstetrics, Gynaecology, and Neonatology, University
of Parma, Parma, Italy.
Patient(s): A 41-year-old, nulliparous, white woman who developed massive ascites and hydrothorax after administration
of 0.50 mg/day of subcutaneous leuprolide acetate, beginning at the midluteal phase.
Intervention(s): Down-regulation with the gonadotropin-releasing hormone analogue was discontinued, and therapy
was started with furosemide 50 mg/day for 10 days.
Main Outcome Measure(s): Successful medical reduction of ascites and hydrothorax.
Result(s): Resolution of symptoms.
Conclusion(s): A comprehensive MEDLINE search revealed this to be the first reported case of massive ascites
and hydrothorax after leuprolide acetate administration (0.5 mg daily) in a down-regulated woman undergoing assisted
reproduction. This case can be explained by an increase in capillary permeability, which resulted in a rapid
fluid shift from the intravascular space into the third space. We believe that ascites in our patient resulted from an
increase in estradiol in the ovaries, due to a direct action of the gonadotropin-releasing hormone analogue on the
corresponding ovarian receptors in the first few days after the start of therapy
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
- …
