1,917,403 research outputs found

    CAD/CAM selection for small manufacturing companies

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    Plan BIn today's fast paced world, CAD/CAM systems have become an essential element in manufacturing companies throughout the world. Technology and communication are changing rapidly, driving business methods for organizations and requiring capitalization in order to maintain competitiveness. Knowledge prior to investing into a system is crucial in order to maximize the benefits received from changing CAD/CAM systems. The purpose of this study is to create a methodology to aid small manufacturing companies in selecting a CAD/CAM system. The objectives are to collect data on CAD/CAM systems that are available in the market today, identify important criteria in system selection, and identify company evaluation parameters

    Tecnologia CAD/CAM

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    TCC (graduação) – Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Odontologia.Nas últimas décadas, ocorreu um rápido avanço da ciência e um grande desenvolvimento tecnológico em diversas áreas. Neste contexto, a tecnologia CAD/CAM (do inglês Computer Aided Design/Computer Aided Manufacturing, que significa Desenho Auxiliado por Computador/Usinagem Auxiliada por Computador), muito utilizada na indústria, foi introduzida na odontologia, possibilitando a automatização do processo de fabricação de restaurações indiretas, com maior controle de qualidade e rapidez. Este trabalho teve como objetivo, através de uma revisão de literatura, descrever as etapas de produção, os sistemas disponíveis, tipos e propriedades dos materiais que podem ser utilizados, assim como os benefícios e as limitações desta tecnologia para que se possa fazer uma correta indicação do seu uso.In the past few decades, there has been a rapid progress of science and a major technological development in several areas. In this context, CAD/CAM (Computer Aided Design/Computer Aided Manufacturing), which is widely used in other areas, was introduced in dentistry, allowing the automation of the manufacturing process of restoration with greater quality control and speed. This study aimed, through literature review, to describe available systems, stages of production, types and materials properties, as well as the benefits and limitations of this technology to elucidate a proper indication of its use

    X. Etudes cam. I. Essai de translittération raisonnée du cam par le groupe de recherches cam

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    Groupe de recherche Cam. X. Etudes cam. I. Essai de translittération raisonnée du cam par le groupe de recherches cam. In: Bulletin de l'Ecole française d'Extrême-Orient. Tome 64, 1977. pp. 243-255

    Translation and adaptation of an international questionnaire to measure usage of complementary and alternative medicine (I-CAM-G)

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    BACKGROUND: The growing body of data on prevalence of complementary and alternative medicine (CAM) usage means there is a need to standardize measurement on an international level. An international team has published a questionnaire0020 (I-CAM-Q), but no validation has yet been provided. The aim of the present study was to provide a German measurement instrument for CAM usage (I-CAM-G) which closely resembles the original English version, and to assess it's performance in two potential samples for measuring CAM usage. METHODS: The English I-CAM-Q questionnaire was translated into German, and adapted slightly. The resulting I-CAM-G questionnaire was then pre-tested on N=16 healthy volunteers, and 12 cognitive interviews were carried out. The questionnaire was employed in a sample of breast cancer patients (N=92, paper and pencil), and a sample from the general population (N=210, internet survey). Descriptive analyses of items and missing data, as well as results from the cognitive interviews, are presented in this paper. RESULTS: The translated questionnaire had to be adapted to be consistent with the German health care system. All items were comprehensible, whereby some items were unambiguous (e.g. CAM use yes/no, helpfulness), while others gave rise to ambiguous answers (e.g. reasons for CAM use), or high rates of missing data (e.g. number of times the CAM modality had been used during the last 3 months). 78% of the breast cancer patients and up to 85% of a sample of the general population had used some form of CAM. CONCLUSIONS: Following methodologically sound and comprehensive translation, adaptation and assessment processes using recognized translation procedures, cognitive interviews, and studying the performance of the questionnaire in two samples, we arrived at a German questionnaire for measuring CAM use which is comparable with the international (English) version. The questionnaire appropriately measures CAM use, with some items being more appropriate than others. We recommend the development of a short version

    The Effect of Using Computer Technology Tools to Enhance the Teaching-Learning Process in CAD-CAM-CNC Module in Mechanical Engineering Subject Area

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    This study presents the evaluation of Computer Assisted Learning (CAL) package included in the teaching and learning methodology of computer aided design- computer aided design - computer numerical control (CAD-CAM-CNC) module. Three groups of students with similar pre-abilities were exposed to three different teaching learning methodologies.The effectiveness of these three methods was determined by questionnaires completed by the students and collected by first author. Their answers were analysed quantitatively and qualitatively. The various categories used in the questionnaire was student’s attitudes towards learning CAD-CAM-CNC subjects, students’ opinions about their lecturers approaches to teaching process, students’ opinions and views about various aspects the CAD-CAM-CNC. The study concludes that the students taught with a combination of CAL package and traditional methods were more effective, efficient and satisfied with their learning experiences. So the proposed hybrid learning method (CAI plus traditional teaching method) is most suited for CAD-CAM-CNC teaching. Computer Technology; Computer-Assisted Instruction (CAI); Computer Assisted Learning (CAL); Computer Aided Design (CAD); Computer Aided Manufacturing (CAM); Computer Numerical Control (CNC)

    CAM-TAMA Association Strengthening Twinning Project : technical report

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    Appendix not includedTanzania is one of ten countries contributing to 61% and 66% of the global total of maternal and newborn deaths, respectively. There is a critical shortage of skilled professionals to provide adequate care - about 2,720 midwives in Tanzania and 140 obstetricians, representing a combined density of only .2 maternity health providers per 1000 population. Through this project, Canadian Association of Midwives (CAM) and its development partner Tanzanian Registered Midwives Association (TAMA) have increased capacity to provide critical support to member midwives, supporting improved health outcomes for women and newborns in both countries

    Uma metodologia para integração CAD/CAPP/CAM voltada para manufatura remota de peças rotacionais baseada na internet

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    Tese [doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-graduação em Engenharia MecânicaEsta tese de doutorado apresenta uma metodologia para integração CAD/CAPP/CAM voltada para manufatura remota de peças rotacionais via Internet, em especial os protocolos associados à World Wide Web, bem como a implementação de um sistema computacional baseado na arquitetura proposta, que permitiu a validação da metodologia concebida. Esta metodologia, denominada WebMachining (http://WebMachining.AlvaresTech.com), descreve uma arquitetura para implementação do sistema integrado CAD/CAPP/CAM via Web, definindo um arcabouço para um sistema integrado CAD/CAPP/CAM via Internet

    Recursos CAD/CAM voltados ao modelamento e a usinagem de cavidades para moldes, com estudo de casos de aplicação

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    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro TecnologicoÉ notório, e cada vez mais crescente, a substituição de diversos materiais existentes no mercado pelo plástico, principalmente na área da engenharia. Associado a este crescimento, aumentam as exigências sobre os produtos de plástico, em termos de qualidade, preço, formas geométricas mais complexas e tolerâncias cada vez mais apertadas. Somado-se isto, também tem-se exigido prazos cada vez menores para um novo produto chegar ao mercado. Estes fatores vêm pressionando os fabricantes de moldes a procurarem novos métodos de fabricação em substituição aos meios tradicionais, visto que estes estão cada vez correspondendo menos a estas exigências. O auxílio do computador, na fabricação de moldes, vem sendo uma solução pretendida por estas empresas, através das tecnologias CAD/CAM, a exemplo dos bons resultados alcançados por outras áreas. As primeiras implantações destas tecnologias, no entanto, demonstraram que os sistemas precisam ser adaptados ao setor, devido principalmente, às necessidades peculiares

    Producciones de la Carrera de Artes Musicales (CAM)

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    Investigaciones y publicaciones de la CAM

    Nuclear translocation and signalling of L1-CAM in human carcinoma cells requires ADAM10 and presenilin/gamma-secretase activity

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    L1-CAM (L1 cell-adhesion molecule), or more simply L1, plays an important role in the progression of human carcinoma. Overexpression promotes tumour-cell invasion and motility, growth in nude mice and tumour metastasis. It is feasible that L1-dependent signalling contributes to these effects. However, little is known about its mechanism in tumour cells. We reported previously that L1 is cleaved by ADAM (a disintegrin and metalloprotease) and that the cytoplasmic part is essential for L1 function. Here we analysed more closely the role of proteolytic cleavage in L1-mediated nuclear signalling. Using OVMz carcinoma cells and L1-transfected cells as a model, we found that ADAM10-mediated cleavage of L1 proceeds in lipid raft and non-raft domains. The cleavage product, L1-32, is further processed by PS (presenilin)/gamma-secretase to release L1-ICD, an L1 intracellular domain of 28 kDa. Overexpression of dominantnegative PS1 or use of a specific gamma-secretase inhibitor leads to an accumulation of L1-32. Fluorescence and biochemical analysis revealed a nuclear localization for L1-ICD. Moreover, inhibition of ADAM10 and/or gamma-secretase blocks nuclear translocation of L1-ICD and L1-dependent gene regulation. Overexpression of recombinant L1-ICD mediates gene regulation in a similar manner to full-length L1. Our results establish for the first time that regulated proteolytic processing by ADAM10 and PS/gamma-secretase is essential for the nuclear signalling of L1 in human carcinoma cell lines. Key words: a disintegrin and metalloprotease 10 (ADAM10), L1 cell-adhesion molecule (L1-CAM), nuclear translocation, presenilin (PS)/gamma-secretase activity, raft, signalling
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