819 research outputs found

    CXCR4-mediated glutamate exocytosis from astrocytes

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    The role of astrocytes as structural and metabolic support for neurons is known since the beginning of the last century. Because of their strategic localization between neurons and capillaries they can monitor and control the level of synaptic activity by providing energetic metabolites to neurons and remove excess of neurotransmitters. During the last two decades number of papers further established that the astrocytic plasma-membrane G-protein coupled receptors (GPCR) can sense external inputs (such as the spillover of neurotransmitters) and transduce them as intracellular calcium elevations and release of chemical transmitters such as glutamate. The chemokine CXCR4 receptor is a GPCR widely expressed on glial cells (especially astrocytes and microglia). Activation of the astrocytic CXCR4 by its natural ligand CXCL12 (or SDF1 alpha) results in a long chain of intracellular and extracellular events (including the release of the pro-inflammatory cytokine TNF alpha and prostanglandins) leading to glutamate release. The emerging role of CXCR4-CXCL12 signalling axis in brain physiology came from the recent observation that glutamate in astrocytes is released via a regulated exocytosis process and occurs with a relatively fast time-scale, in the order of few hundred milliseconds. Taking into account that astrocytes are electrically non-excitable and thus exocytosis rely only on a signalling pathway that involves the release Ca2+ from the internal stores, these results suggested a close relationship between sites of Ca2+ release and those of fusion events. Indeed, a recent observation describes structural sub-membrane microdomains where fast ER-dependent calcium elevations occur in spatial and temporal correlation with fusion events. (C) 2010 Elsevier B.V. All rights reserved

    Cordilura bezzi

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    Cordilura bezzi (SACK, 1937) Cordylura bezzi (SACK, 1937): 18 L e c t o t y p e: male, Livrio, without data, designated by VOCKEROTH 1954 (SDEI). C o m m e n t: This species was placed by ŠIFNER (2008) in the genus Bucephalina MALLOCH, 1909.Published as part of V, Marco, 2021, Annotated supplements to catalogues of the family Scathophagidae (Diptera) in the world, with new taxonomic data, notes on some species and new list of species, pp. 1267-1306 in Linzer biologische Beiträge 52 (2) on page 1279, DOI: 10.5281/zenodo.503898

    Questionario e dintorni

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    Il volume si configura come un manuale di metodologia della ricerca sociale centato sul questionario ma attento anche ai "dintorni", ossia ai problemi epistemologici sollevati dal suo spesso acritico utilizzo, al campionamento e all'analisi dei dat

    Titania nano-coated quartz wool for the photocatalytic mineralisation of emerging organic contaminants

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    Many emerging contaminants pass through conventional wastewater treatment plants, contaminating surface and drinking water. The implementation of advanced oxidation processes in existing plants for emerging contaminant remediation is one of the challenges for the enhancement of water quality in the industrialised countries. This paper reports on the production of a TiO2 nano-layer on quartz wool in a relevant amount, its characterisation by X-ray diffraction and scanning electron microscopy, and its use as a photocatalyst under ultraviolet radiation for the simultaneous mineralisation of five emerging organic contaminants (benzophenone-3, benzophenone-4, carbamazepine, diclofenac, and triton X-100) dissolved in deionised water and tap water. This treatment was compared with direct ultraviolet photolysis and with photocatalytic degradation on commercial TiO2 micropearls. The disappearance of every pollutant was measured by high performance liquid chromatography and mineralisation was assessed by the determination of total organic carbon. After 4 hours of treatment with the TiO2 nano-coated quartz wool, the mineralisation exceeds 90% in deionised water and is about 70% in tap water. This catalyst was reused for seven cycles without significant efficiency loss. © IWA Publishing 2018

    Strategie di valutazione

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    Il volume raccoglie le prime riflessioni degli autori italiani fondatori dell'Associazione Italiana di Valutazione e pone le basi per i successivi sviluppi di molte importanti opere degli autori che hanno collaborato a questo volum

    A redescription of Tephritis zonogastra Bezzi, 1913 (Diptera: Trypetidae).

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    Die vorliegende Arbeit enthält eine ausführliche Nachbeschreibung von Tephritis zonogastra Bezzi, ES wird vermutet, daß Bezzi\u27s Holotypus, obgleich seine Beschreibung keine Angaben über das Geschlecht enthält, ein Männchen war, so daß hiermit die Neubeschreibung des Weibchens vorgelegt werden kann.Tephritis zonogastra Bezzi is redescribed in detail. It is suggested that although Bezzi in his original description made no mention of the sex,the holotype described by him was a male. The description of the female given by the present author may, therefore, be regarded as new

    Czernyola Bezzi

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    Genus CZERNYOLA Bezzi Czernyola Bezzi, Wien. ent. Zeitung 26: 52, 1907. Craspedochaeta Czerny, \ i\Tien.ent. Zeitung 22: 103, 1903, nee Macquart, 1851. Tonnoiria Malloch, Ann. Mag. Nat. Hist. 26: 98, 1929. Hendel has described a species, C. biseta, from Formosa, and I have described a species from the Society Islands as Tonnoiria. palliseta.Published as part of Mailoch, J. R., 1942, Trypetidae, Otitidae, Helomyzidae, And Clusiidae of Guam (Diptera), pp. 201-210 in Insects of Guam I, Honolulu, Hawaii :Bernice P. Bishop Museum on page 209, DOI: 10.5281/zenodo.516362

    Gastrozona Bezzi

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    Genus Gastrozona Bezzi Gastrozona Bezzi, 1913: 105. Type species: Tephritis fasciventris Macquart Diagnosis. Head moderately to distinctly higher than long, with 2 pairs of orbital and 3¯4 pairs of frontal setae; ocellar seta vestigial or moderately well developed; face slightly projecting at lower margin; first flagellomere dorsoapically rounded; arista moderately to long-plumose. Scutal and wing pattern often slightly sexually dimorphic, banded; cells bc and c hyaline except base of cell c often fulvous; Male with abdominal tergum II not enlarged or expanded over sides of tergum III; anal papillae present, proctiger larger than epandrium, opaque or hyaline, setulose; posterior lobe of surstylus often longer and broader than anterior lobe, glans of phallus sclerotised, acrophallus sclerotised with two semitubular lobes, praeputium smooth without sculpturing. Female with 2 oblong or club-shaped spermathecae with apical papillae; aculeus elongate, weakly trilobed with two preapical steps and with four pairs of preapical setae. It is similar to genus Paragastrozona Shiraki but the latter differs in possessing fulvous bc and c; broad, flat aculeus tip and mushroom shaped spermatheca.Published as part of David, K. J. & Hancock, D. L., 2017, A new species of Gastrozona Bezzi (Diptera: Tephritidae: Dacinae: Gastrozonini) with an updated key to species from India, pp. 55-64 in Zootaxa 4216 (1) on page 56, DOI: 10.5281/zenodo.22982

    Fotografare per vivere

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    Il testo analizza criticamente la vicenda fotografica di Ulisse Bezzi (n. 1925) autore rimasto praticamente sconosciuto fino agli anni Duemila quando un importante gallerista newyorkese, Keith De Lellis, acquista buona parte della sua produzione dedicandogli poi alcune mostre negli Stati Uniti. La produzione di Bezzi oscilla tra echi di neorealismo e interessanti riferimenti al clima dell'incomunicabilità celebrato da Antonioni nei suoi film di inizio anni Sessanta

    A new species of Haematobosca Bezzi (Diptera: Muscidae) from Thailand

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    Pont, Adrian C, Duvallet, Gérard, Changbunjong, Tanasak (2020): A new species of Haematobosca Bezzi (Diptera: Muscidae) from Thailand. Zootaxa 4763 (4): 538-544, DOI: 10.11646/zootaxa.4763.4.
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