28 research outputs found
Kurşun Nitrat Ve Kadmiyum Klorür’Ün Rat Beyin Dokusu Üzerine Toksik Etkisi Ve Sesamol’Ün Koruyucu Rolü
No full textAğır metaller, canlılarda toksik etkilere sebep olmaktadır. Kurşun ve kadmiyum endüstride sıklıkla kullanılan ağır metallerdir. Bunlar akut ve kronik zehirlenmelere sebep olmaktadırlar. Sesamol (5-hidroksi-1,3-benzodioksil) metilendioksil grubu içeren antioksidan özelliği olan bir bileşiktir. Sesamol susam yağından elde edilir. Bu çalışmada, kurşun nitrat ve kadmiyum klorürün ratların beyin dokusunda oluşturabileceği toksik etki ve sesamolün koruyucu rolü biyokimyasal olarak araştırılmıştır. Bu amaçla oksidatif stres parametreleri olan süperoksit dismutaz (SOD), katalaz (CAT), glutatyon peroksidaz (GPx), glutatyon-S-transferaz (GST) enzim aktiviteleri ile lipid peroksidasyonun son ürünü olan malondialdehit (MDA) seviyeleri araştırılmıştır. Çalışmada, deney hayvanları 8 gruba ayrılmıştır. 1. Kontrol grubu. 2. Sesamol (50 mg/kg v.a) uygulanan grup. 3. Kurşun nitrat (90 mg/kg v.a) muameleli grup. 4. Kadmiyum klorür (3 mg/kg v.a) muameleli grup. 5. Kurşun nitrat ve kadmiyum klorür muameleli grup. 6. Kurşun nitrat ve sesamol uygulanan grup. 7. Kadmiyum klorür ve sesamol muameleli grup. 8. Kurşun nitrat, kadmiyum klorür ve sesamol muameleli grup. 28 gün süren deneylerin sonunda, kurşun nitrat, kadmiyum klorür ve kurşun+kadmiyum muameleli ratların beyin dokularında SOD, CAT, GPx ve GST seviyelerinde kontrol ve sesamol grubuna göre istatistiksel olarak anlamlı azalma olduğu görülmüştür. Sesamol ile birlikte kurşun nitrat, kadmiyum klorür ve kurşun nitrat+kadmiyum klorür uygulanan sıçanların beyin dokularında ise enzim seviyelerinde istatiksel olarak anlamlı bir artış olduğu gözlenmiştir. Kurşun nitrat, kadmiyum klorür ve kurşun+kadmiyum muameleli ratların beyin dokuları, MDA seviyesi bakımından kontrol ve sesamol muameleli ratlarla karşılaştırıldığında, MDA seviyesinde istatiksel olarak anlamlı bir artış gözlenmiştir. Sesamolün kurşun nitrat ve kadmiyum klorürün oluşturduğu lipit peroksidasyonu azalttığı gözlenmiştir. Sonuç olarak ağır metallerin verdiği oksidatif hasar üzerinde sesamolün iyileştirici rolü olduğunu söylemek mümkündürHeavy metals cause toxic effects on living things. Lead and cadmium are heavy metals frequently used in industry. These cause acute and chronic poisoning. Sesamol (5-hydroxy-1,3-benzodioxyl) is an antioxidant compound containing methylenedioxyl group. Sesamol is derived from sesame oil. In this study, the toxic effects of lead and cadmium on the brain tissue of rats and the protective role of sesamol were investigated biochemically. For this purpose, the oxidative stress parameters superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione-S-transferase (GST) enzyme activities and malondialdehyde (MDA) levels, which are the end product of lipid peroxidation, were investigated. In the study, experimental animals were divided into 8 groups. 1. Control group. 2. Sesamol (50 mg / kg bw) treated group. 3. Lead nitrate (90 mg / kg bw) treated group. 4. Cadmium chloride (3 mg / kg bw) treated group. 5. Lead nitrate and cadmium chloride treated group. 6. Lead nitrate plus sesamol treated group. 7. Cadmium chloride plus sesamol treated group. 8. Lead nitrate and cadmium chloride plus sesamol treated group. At the end of the experiments which lasted for 28 days, it was observed that there was a statistically significant decrease in SOD, CAT, GPx and GST levels in the brain tissues of lead nitrate, cadmium chloride and lead + cadmium treated rats compared to the control and sesamol groups. It was observed that there was a statistically significant increase in enzyme levels in the brain tissues of rats who were administered lead nitrate, cadmium chloride and lead nitrate + cadmium chloride together with sesamol. When the brain tissues of lead nitrate, cadmium chloride and lead + cadmium treated rats were compared with the control and sesamol treated rats, a statistically significant increase was observed in the MDA level. It has been observed that sesamol reduces lipid peroxidation caused by lead nitrate and cadmium chloride. As a result, it is possible to say that sesamol has a healing role on oxidative damage caused by heavy metals
Reconstruction of sternal cleft with autologous cartilage graft in an adult
No full textSternal cleft is a rare chest wall deformity associated with various malformations. Primary closure is the gold standard in the newborn period. Alternative techniques are possible for older patients. A 23-year-old woman with a partial sternal cleft and no additional deformity, underwent reconstruction using costal cartilage grafts. Postoperative physical and functional were excellent. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav
Effect of pore structure properties on strength properties of hybrid silica fume mortars containing randomly distributed carbon fibers
No full textInvestigating the changes in pore structure features caused by fiber inclusion is crucial with respect to comprehending the beneficial use of fiber in calcium silicate structure. This study focused on the relationships between pore structure features and mechanical properties in carbon fiber (CF)-incorporated hybrid silica fume (HSF) mortars. For this purpose, randomly distributed fiber-incorporated silica fume (SF) mortar mixtures containing 0%, 0.15%, 0.3%, 0.45% and 0.6% CF in weight basis were prepared and the effects of CF inclusion on pore structure features were investigated. The results indicated that CF inclusion deeply affects the gel pore formation and pore area characteristics of HSF cement matrix. Based on the pore modification effect, the volume of pores in pore sizes between 10–100 and 550–800 nm showed great influences on the compressive strengths of HSF mortars with R2 of 0.93 and 0.95 at 7- and 28-day samples, respectively. In addition, 7- and 28-day flexural strengths could be predicted by the measurement of critical pore contents (in pore sizes between 3–10 and 1000–10,000 nm, respectively) with correlation coefficients of 0.97 and 0.90, respectively. This work provides an innovative approach by addressing the critical pore contents for strength prediction in fiber-incorporated HSF samples. © 2021, The Author(s), under exclusive licence to Springer Nature Switzerland AG
Covid-19'un Türkiye'nin ihracatına etkisi
No full textKitap adı: COVID-19 PANDEMİSİNİN İDARİ, SİYASİ, ULUSLARARASI İLİŞKİLER, EKONOMİ VE İŞLETMELER ÜZERİNDEKİ ETKİLERİ -- Bölüm Adı:COVID-19’UN TÜRKİYE’NİN İHRACATINA ETKİSİ, YUMUŞAK İBRAHİM GÜRAN, PİŞKİN METİN, KARABAŞ SEMRA, Yayın Yeri: Ekin Yayınevi, Editör: Yakup Bulut, Basım sayısı:1, Sayfa sayısı:254, ISBN:978-625-8024-11-1, Bölüm Sayfaları:117 -128İÇİNDEKİLER: BİRİNCİ BÖLÜM TÜRKİYE’NİN KORONAVİRÜSLE MÜCADELEDE KULLANDIĞI YENİLİKÇİ UYGULAMALAR Prof. Dr. Yakup BULUT Arş. Gör. Muhammed Miraç ASLAN İKİNCİ BÖLÜM TARİHSEL SÜREÇTE PANDEMİLERİN SİYASET ÜZERİNDEKİ ETKİSİ Doç. Dr. Ahmet KESER ÜÇÜNCÜ BÖLÜM COVID-19 SALGINI İLE MÜCADELE YAKLAŞIMLARI: SEÇİLİ ÜLKE İNCELEMELERİ Prof. Dr. Abdullah ÇELİK Arş. Gör. Ali Burak AKSUNGUR DÖRDÜNCÜ BÖLÜM COVID-19 VE KENTLERİN DÖNÜŞÜMÜ Prof. Dr. Hasan YAYLI BEŞİNCİ BÖLÜM COVID-19 PANDEMİ SÜRECİNDE TÜRKİYE'DE E-BELEDİYE UYGULAMALARI Doç. Dr. Seda H. BOSTANCI Doç.Dr. Seda YILDIRIM ALTINCI BÖLÜM KORONAVİRÜS SALGINI VE DIŞ TİCARETE ETKİLERİ ÜZERİNE BİR DEĞERLENDİRME Dr. Öğretim Üyesi Ertan BECEREN Doç. Dr. Emine FIRAT Prof. Dr. Berna BALCI İZGİ YEDİNCİ BÖLÜM COVID-19’UN TÜRKİYE’NİN İHRACATINA ETKİSİ Prof. Dr. İbrahim Güran YUMUŞAK Dr. Öğretim Üyesi Metin PİŞKİN Yüksek Lisans Öğrencisi Semra KARABAŞ SEKİZİNCİ BÖLÜM COVID-19’UN TURİZM SEKTÖRÜ ÜZERİNDEKİ ETKİSİ: TÜRKİYE ÖRNEĞİ Yüksek Lisans Öğrencisi Burak BEDİR Doç. Dr. Ferda Nakıpoğlu ÖZSOY DOKUZUNCU BÖLÜM COVID-19 PANDEMİSİNİN TÜRKİYE EKONOMİSİ AÇISINDAN EMEK PİYASASI VE EKONOMİK BÜYÜME ÜZERİNE ETKİSİNİN DEĞERLENDİRİLMESİ Arş. Gör. Bengü KAYAPALI ONUNCU BÖLÜM COVID-19 PANDEMİ SÜRECİNDE KÜRESEL VE ULUSAL DÜZEYDE ÜRETİM VE ULUSLARARASI TİCARET GÖSTERGELERİ Prof. Dr. Birol ERKAN ONBİRİNCİ BÖLÜM HELAL PAZAR VE HELAL LOJİSTİK FIRSATLARI: COVID 19 KAPSAMINDA BİR DEĞERLENDİRME Prof. Dr. Taner AKÇACI Yüksek Lisans Öğrencisi Mehmet BOZKURT ONİKİNCİ BÖLÜM KORONAVİRÜS’ÜN (COVID-19) TÜRKİYE’DE E-TİCARETE ETKİLERİ Prof. Dr. Oğuz YILDIRIM Doktora Öğrencisi Emrecan AYDIN ONÜÇÜNCÜ BÖLÜM KRİZ, AFET VE SALGIN DÖNEMLERİNDE FİRMALARIN TEDARİK ZİNCİRİNDE RİSK YÖNETİMİNİN ÖNEMİ Arş. Gör. Burcu Yengil BÜLBÜL Arş. Gör. Maide Betül AKSOY ONDÖRDÜNCÜ BÖLÜM TÜRKİYE’DE COVID-19 SONRASI EKONOMİK GELİŞMELER Arş.Gör. Berna DOĞAN BAŞAR ONBEŞİNCİ BÖLÜM COVID-19 PANDEMİSİNİN DENİZ YOLU TAŞIMACILIĞINA ETKİLERİ Arş. Gör. Maide Betül AKSOY Arş.Gör. Burcu YENGİL BÜLBÜL ONALTINCI BÖLÜM COVID -19’UN ULUSLARARASI İŞLETMECİLİK FAALİYETLERİNE ETKİSİ Prof. Dr. Hüseyin ALT
Lygaeus equestris Heteroptera Lygaeidae de dişi üreme sisteminin anatomisi ve histolojisi
No full textThe prediction level of teachers' organizational citizenship behaviors on the successful practice of shared leadership [Ö?retmenlerin örgütsel vatandaşlik davranişlarinin paylaşilan liderli?in gerçekleşmesini yordama düzeyi]
No full textProblem Statement: Defined as the actions that personnel voluntarily take beyond their formal job description, organizational citizenship behavior is regarded as a premise for shared leadership, a management style that is frequently used in organizations today. The relevant literature suggests that organizational citizenship behavior can provide the team effectiveness required for the successful practice of shared leadership. The procedure of this leadership style involves sharing tasks and responsibilities, and thus requires cooperation. Considering the personnel's expectations for this type of leadership, it is not possible for members who exhibit poor organizational citizenship behaviors to meet these expectations. A school under shared leadership functions as a team, and all members of this team must share leadership in every field and devote themselves to performing their responsibilities if they wish to achieve the school's mission satisfactorily. This study tried to discover the extent to which teachers' levels of commitment to organizational citizenship in primary schools predict the successful practice of shared leadership. Purpose of Study: The author wished to determine the extent to which teachers' organizational citizenship behaviors in primary schools predict the successful practice of shared leadership. Methods: This research is a correlational study. The sample comprised 364 primary school teachers working in Zonguldak. The data were collected using a group-level organizational citizenship behaviors scale and a shared leadership perception scale. Findings and Results: The findings of the study revealed that there is a high level of positive correlation between primary school teachers' levels of organizational citizenship behaviors and the successful practice of shared leadership. For example, the sub-dimension of organizational citizenship behaviors towards individuals of the organization predicts significantly in a positive way and at a high level the joint completion of tasks, mutual skill development, decentralized interaction among personnel, and emotional support dimensions of shared leadership. In addition, the subdimension of organizational citizenship behaviors towards the organization predicts significantly at a low level the successful practice of joint completion of tasks and emotional support dimensions of shared leadership, but this sub-dimension offered no significant prediction of the successful practice of mutual skill development and decentralized interaction among personnel. According to the findings, it can be stated that organizational citizenship behaviors are significant predictors of the successful practice of shared leadership. Conclusions and Recommendations: According to the findings of the study, when the correlations between group-level organizational citizenship behaviors and both total shared leadership and its factors are examined, it can be seen that the correlation between the level of individual organizational citizenship behaviors and shared leadership is higher than other correlations. It is also understood that the level of organizational citizenship behaviors predicts positively and highly the successful practice of shared leadership and that the prediction of the sub-dimension of organizational citizenship behaviors towards individuals is more significant and at higher level than that of the organizational citizenship behaviors towards the organization. There is also research in the literature supporting the finding that organizational citizenship behaviors, particularly the individual-oriented ones, predict significantly the successful practice of shared leadership. Therefore, it was confirmed that the level of organizational citizenship behaviors predicts shared leadership significantly to a considerable extent. This situation is also understood from the goodness of fit indices. As a result, it can be suggested that the organizations planning to employ shared leadership in their executive structures should take actions to empower organizational citizenship behaviors as a premise of shared leadership
Host Immune Response to Dental Implants
No full textBiocompatibility and biostability are the key properties of dental implants in the “oral environment,” in order to optimize their performance before or after functional loading. Uneventful host defense to dental implant insertion starts with a more favorable immune response that promotes wound healing around the jawbone and soft mucosal tissue. The growth of a biofilm on the surface of an implant is an igniting factor of the inflammatory response of the surrounding peri-implant tissues. At an initial stage, peri-implant mucositis is established, whereas the spread of inflammation towards the supportive bone leads to peri-implantitis. The molecular content of peri-implant crevicular fluid (PICF) offers a medium for “measurable biological indicators” of peri-implant diseases and potentially new targets for the immunomodulatory treatment of peri-implant diseases. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2022
