655 research outputs found
In vitro and in vivo characterization of the RE-1 Silencing Transcription Factor (REST) activity under neuroinflammatory conditions
No full textThe ability to specifically target epigenetic and molecular mechanisms involved in neuronal development could be an alternative therapeutic strategy for neuroinflammatory/neurodegenerative disorders such as Multiple Sclerosis (MS). The transcriptional repressor RE1-Silencing Transcription Factor (REST) regulates neurogenesis and neuronal identity through cell-specific gene repression, allowing expression of its targets in mature neurons where REST is quiescent. REST dysregulation has been implicated in several neurodegenerative disorders, including Alzheimer and Huntington diseases, tumors of the nervous system, and epilepsy.
We found that REST is overexpressed in the spinal cord of mice with experimental autoimmune encephalomyelitis (EAE), suggesting that its dysregulation might be an important factor in the pathogenesis of the disease. Starting from these observations, we have firstly analyzed the expression of REST target genes in EAE and characterized the cell-specificity of REST overexpression, investigating the differential contribution of neuronal and glial cell populations to REST upregulation. Moreover, in order to mimic the inflammatory EAE scenario, we have analyzed REST activity in primary neuron cultures treated with various pro-inflammatory cytokines. Altogether, this study provides the basis for understanding the molecular mechanisms of REST expression during brain inflammation and its implication in the subsequent neurodegenerative processes
Source data file for the article authored by Tafazoli and colleagues on invariant object representations in rat visual cortex
No full textThis data file provides the full data set processed in the article “Emergence of transformation-tolerant representations of visual objects in rat lateral extrastriate cortex” by Sina Tafazoli, Houman Safaai, Gioia De Franceschi, Federica Bianca Rosselli, Walter Vanzella, Margherita Riggi, Federica Buffolo, Stefano Panzeri and Davide Zoccolan. A detailed description of the file is provided in the companion "Readme.pdf" file
Draunara, installation, Federica Cellini, 2014
No full text Draunara, Federica Cellini, Ana B.K, widewalls.ch , 26/05/2014 "Washed away onto the shores of the island, migrants from Africa keep arriving to Lampedusa, a small island just off the coast of Sicily. (...) The Unstoppable Tempest Draunara takes its name from the local term for a storm that swoops over the island coming from the sea. The author of the piece draws a parallel between the tempest and the overwhelming number of people arriving from the same direction. Although the arrivals ar..
correction idelalisib exposure before allogenic stem cell transplantation in patients with follicular lymphoma an EBMT survey
No full textThe article “Idelalisib exposure before allogeneic stem cell transplantation in patients with follicular lymphoma: an EBMT survey”, written by Leopold Sellner, Johannes Schetelig, Linda Koster, Goda Choi, Didier Blaise, Dietrich Beelen, Fabrizio Carnevale Schianca, Jakob Passweg, Urs Schanz, Emmanuel Gyan, Federica Sora, Nicolaus Kröger, Gerald. G. Wulf, Gwendolyn Van Gorkom, Jiri Mayer, Corentin Orvain, Jean Henri Bourhis, Pavel Jindra, Victoria Potter, Francesco Zallio, Elisabeth Vandenberghe, Stephen Robinson, Patrick J. Hayden, Ibrahim Yakoub-Agha, Silvia Montoto, Peter Dreger, on behalf of the European Society for Blood and Marrow Transplantation Lymphoma and Chronic Malignancies Working Parties, was originally published Online First without Open Access. After publication in volume 55, issue 12, page 2335–2338, the author decided to opt for Open Choice and to make the article an Open Access publication. Therefore, the copyright of the article has been changed to © The Author(s) 2020 and the article is forthwith distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder
Cooking pots from Alassa Pano Mantilaris and Paliotaverna
No full textThis final report on the 1984–2000 investigations at Alassa begins with the presentation of the rescue excavations of the settlement (Chapter 2) and tombs (Chapter 3) at Pano Mantilaris. This is followed by the account of the elite architecture and associated finds uncovered at Paliotaverna (Chapter 4) and a detailed description and discussion of the remarkable seal impressions found on many of the Alassa pithoi (Chapter 5). In-depth studies of the Alassa pithoi and all of the other pottery found at the site are presented in Chapters 6 and 7 by Priscilla Keswani and Ariane Jacobs, respectively. Federica Spagnoli presents a report on cooking pots in chapter 7. Reports by other specialists on a variety of topics may be found in the 10 appendices: the cylinder and stamp seals (Aruz), metallurgical finds (Kassianidou and Van-Brempt), marked pottery (Hirschfeld), C14 dates (Manning), human remains (Lorentz), faunal remains (Croft), coins (Destrooper), ground stone objects (Souter), and archaeometric studies of the pithoi (Nodarou) and other pottery (Jacobs et al.). The results from all of these studies are integrated within the conclusions that the author offers in Chapter 8 regarding the chronology and importance of Alassa within the broader cultural and sociopolitical context of LBA Cyprus
Correction to: Impact of a mixed educational and semi-restrictive antimicrobial stewardship project in a large teaching hospital in Northern Italy (Infection, 10.1007/s15010-017-1063-7)
No full textA technical error led to incorrect rendering of the author group in this article. The correct authorship is as follows: Daniele Roberto Giacobbe1, Valerio Del Bono1, Malgorzata Mikulska1, Giulia Gustinetti1, Anna Marchese2, Federica Mina3, Alessio Signori4, Andrea Orsi5, Fulvio Rudello6, Cristiano Alicino5, Beatrice Bonalumi3, Alessandra Morando7, Giancarlo Icardi5, Sabrina Beltramini3, Claudio Viscoli1; On behalf of the San Martino Antimicrobial Stewardship Group
The Planning of Socialist Urbanity: The New City of Kukës in Albania.
No full textThis paper titled "The Planning of Socialist Urbanity: The New City of Kukës in Albania" has been submitted in March 2022 (abstract submission) to the “Ngā Pūtahitanga / Crossings: 39th Annual SAHANZ Conference and 16th Australasian UHPH Conference" hosted at the Te Pare School of Architecture and Planning, University of Auckland, Waipapa Taumata Rau, New Zealand, in 25-27 November 2022 (hybrid online/in situ format). This paper has been peer-reviewed and it has been accepted for publication in December 2022, and published in July 2023 in the Annual Conferences Proceedings of the Society of Architectural Historians, Australia and New Zealand (SAHANZ), “Ngā Pūtahitanga / Crossings”, Volume 39, edited by Julia Gatley and Elizabeth Aitken Rose, Auckland: SAHANZ 2023. ISBN: 978-0-646-88028-0 (ISSN 2653-4789 - online).
More info on the SAHANZ/UHPH Joint Conference can be found here: https://www.sahanz.net/events/nga-putahitanga-crossings-a-joint-conference-of-sahanz-and-the-australasian-uhph-group/
Conference contributions are available online at the following link: https://www.sahanz.net/publications/annual-proceedings/?session=3709
The final paper written by Dr Pompejano can be also accessed and downloaded here: https://www.sahanz.net/wp-content/uploads/Pompejano_2022_SAHANZ.pdf
The paper should be cited as follows:
Federica Pompejano, “The Planning of Socialist Urbanity: The New City of Kukës in Albania.” In Proceedings of the Society of Architectural Historians, Australia and New Zealand: 39, Ngā Pūtahitanga / Crossings, ed. Julia Gatley and Elizabeth Aitken Rose, 379-87. Auckland: SAHANZ, 2023. Accepted for publication December 1, 2022. DOI: 10.55939/a5035pmg1tThis paper should be cited as follows:
Federica Pompejano, "The Planning of Socialist Urbanity: The New City of Kukës in Albania." In Proceedings of the Society of Architectural Historians, Australia and New Zealand: 39, Ngā Pūtahitanga / Crossings, ed. Julia Gatley and Elizabeth Aitken Rose, 379-87. Auckland: SAHANZ, 2023. Accepted for publication December 1, 2022. DOI: 10.55939/a5035pmg1t
Acknowledgement: This article originates from the scientific work conducted by the author during the implementation of the research project "Materializing Modernity – Socialist and Postsocialist Rural Legacy in Contemporary Albania (MaMo)" which has received funding from the European Union's Horizon 2020 Research and Innovation Programme under the Marie Skłodowska-Curie Grant Agreement No. 896925 (https://cordis.europa.eu/project/id/896925). This contribution reflects only the author's view, and the EU Commission is not responsible for any use that may be made of the information it contains
Rural Heritage and Cultural Landscape: Guidelines for Sustainable Seismic Reinforcement of Emilian Historic Rural Building in Italy
No full textAbstractHistoric rural settlements are essential evidences of the Italian cultural heritage because they hand precious architectural, historical and environmental values. Despite its importance, this heritage is rarely protected by specific laws and a great part of these buildings are now abandoned and partially ruined, also as a consequence of the last century mechanized and intensive farming and the consequent lifestyle change. Moreover, the seismic events pose a serious threat to their preservation: indeed, despite they are located in an area - the Italian territory - with a very high seismic risk, often they don’t have any proper anti-seismic device able to prevent a serious damage, or collapse. In this work, the results of the research carried out on a significant number of historic rural buildings in the Emilian area, in Italy, are presented in order to draw up specific guidelines for their sustainable seismic reinforcement and conservation. Indeed, starting from the analysis of the peculiar features of the landscape and of the examined buildings, it's possible to recognize some recurring structures and shapes which identify as many rural architectural types, with similar structural behavior and seismic damage. Thanks to this similarity, it has been possible to set up some reliable guidelines of analysis and intervention which can constitute an easy and expeditious instrument for technicians and restorers in order to safeguard this valuable built heritage, too much neglected until now. The final aim is to evidence the extreme efficacy of a conservation strategy, which can constitute the first guarantee for a sustainable intervention on this precious cultural heritage
Electronic Dictionaries for Information Retrieval, Automatic Textual Analysis and Semantic-Based Data Mining Software
No full textToday Lexicon-Grammar (LG) remains one of the most consistent
Natural Language Processing (NLP) approaches, especially for
Semantic-Based Data Mining (SBDM) and Semantic Web. Its main goal
is to describe all mechanisms of word combinations closely related to the
concrete use of lexical units and to sentence creation. Also, it gives an
exhaustive description of lexical and syntactic structures of several
languages. LG was set up by the French linguist Maurice Gross during
the ‘60s, and subsequently developed for and applied to Italian by
Annibale Elia, Emilio D’Agostino and Maurizio Martinelli. Its
theoretical approach is prevalently based on Zelig Sabbettai Harris’
Operator-Argument Grammar, which assumes that each human language
is a self-organizing system, and that the syntactic and semantic properties
of a given word may be calculated on the basis of the relationships this
word has with all other co-occurring words inside given sentence
contexts. Simple sentences2 are the minimal linguistic meaning structures
upon which LG founds its studies on natural language syntactic features.
In the last twenty years, LG has also reached important results in the
domain of automatic textual analysis and parsing with NLP-oriented
software such as INTEX3, UNITEX4, and more recently NOOJ5.
1 Alberto Postiglione is author of paragraph 4.1. Mario Monteleone is author of
paragraphs 3.1 and 4. Federica Marano is author of paragraphs 3.2 and 4.3. Johanna
Monti is author of sections 1 and 2. Antonella Napoli is author of paragraph 4.2.
2 In LG, a simple sentence is formed by a unique predicative element (a verb, but
also a name or an adjective) plus all the necessary arguments it selects to achieve
acceptability and grammaticality. The study of simple sentences is completed analyzing
the rules of co-occurrence and selection restriction, which are distributional and
transformational rules based on predicate syntactic-semantic properties.
3 For more on INTEX, see http://intex.univ-fcomte.fr/.
4 For more on UNITEX, see http://www-igm.univ-mlv.fr/~unitex/.
5 For more on NooJ, see http://www.nooj4nlp.net/pages/nooj.html.
ALBERTO POSTIGLIONE - MARIO MONTELEONE -
FEDERICA MARANO - JOHANNA MONTI - ANTONELLA NAPOLI1
Università degli Studi di Salerno
ELECTRONIC DICTIONARIES FOR INFORMATION RETRIEVAL,
AUTOMATIC TEXTUAL ANALYSIS AND SEMANTIC-BASED
DATA MINING SOFTWARE
1. Theoretical and analytical framework: Lexicon-Gramma
- …
