30,196 research outputs found

    "A torchlight procession of one". Le choeur de Santa Maria Maggiore de Barletta

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    Bruzelius Caroline. "A torchlight procession of one". Le choeur de Santa Maria Maggiore de Barletta. In: Revue de l'Art, 1999, n°125. pp. 9-19

    Maria Bersani

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    La voce illustra la biografia e l'apporto letterario dato da Maria Bersani alla letteratura per l'infanziaThe headword explains the biography and the contribution of the author Maria Bersani to the children's literatur

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Exploration of novel mechanisms and biomarkers for venous thromboembolism : a genetics and proteomics study

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    Background: Venous thromboembolism (VTE) contributes to a large health burden and incidence increases exponentially with age. ~25% patients will experience a recurrent event and there is a 2-fold risk for death in the following years. Risk prediction remains a challenge. Aims to: Investigate a presumed overlap between cardiovascular disease and VTE. Expand current knowledge of established pathways in VTE risk by combining clinical and genetic epidemiology. Apply affinity proteomics to identify novel plasma susceptibility biomarkers. Methods and results: 39 single nucleotide polymorphisms (SNPs) associated with coronary artery disease (CAD) and 18 risk VTE-SNPs from candidate gene approach studies or genome-wide association studies (GWAS) were identified from a literature search. The SNPs were genotyped in 2,835 women from the ThromboEmbolism Hormone study (TEHS), a Swedish nationwide case-control study in women (2002-2009). Association was assessed with logistic regression. Clinical and genetic predictors that contributed significantly to the fit of the logistic regression model were included in the prediction models. The genetic predictors that contributed to first VTE were assessed in a cohort of 1010 women with VTE from TEHS, followed up until a recurrence, death or November 2011 (TEHS follow-up). The SNP r579459 in the ABO locus was the only CAD-SNP that was significant associated with VTE (OR 1.57 (95% CI: 1.39-1.78, p= 6.4 10-13)). Seven VTE risk-SNPs (F5 rs6025, F2 rs1799963, ABO rs514659, FGG rs2066865, F11 rs2289252, PROC rs1799810 and KNG1 rs710446) with 4 SNP-SNP interactions contributed to the genetic risk score for VTE with an AUC of 0.66 (95% CI: 0.64-0.68). After adding clinical risk factors the AUC attained 0.84 (95% CI: 0.82-0.85). The goodness of fit of the genetic and combined scores improved when significant SNP-SNP interaction terms were included. In TEHS follow-up study, the overall recurrence rate was 20 per 1000 person-years (95% CI; 16-24). Carriers of the risk alleles of F5 rs6025 (FVL) (HR=1.7 (95% CI; 1.1-2.6)) and F11 rs2289252 (HR=1.8 (95% CI; 1.1-3.0)) had significantly higher rates of recurrence compared to non-carriers. The cumulative recurrence was 2.5-fold larger in carriers of both F5 rs6025 and F11 rs2289252 than in non-carriers at 5 years follow-up. Plasma samples from 88 VTE cases and 85 controls, part of the Venous thromboembolism Biomarker Study (VEBIOS), were screened against 408 candidate proteins targeted by 755 antibodies using multiplex bead arrays. Proteins that significantly associated with VTE after Bonferroni correction were tested for replication in plasma samples of 580 cases and 589 controls from the FARIVE study. In VEBIOS, plasma levels of four proteins, HIVEP1, VWF, GPX3 and PDGFB were significantly associated with VTE after Bonferroni correction. VWF and PDGFB successfully replicated in FARIVE with increased plasma levels in VTE cases compared to controls as initially observed in VEBIOS. Conclusion: ABO locus was the only shared genetic risk factor between CVD and VTE. A limited set of genetic predictors improved prediction of incident VTE in women at high risk. Our data indicated that interactions among SNPs increase the goodness of fit when predicting VTE. A combination of genotypes i.e. F11 rs2289252 and FVL, may be of potential clinical relevance for risk prediction for recurrence. Affinity plasma proteomics proved to be a valuable research strategy to discover novel biomarkersList of scientific papersI. Bruzelius M, Strawbridge RJ, Trégouët DA, Wiggins KL, Gertow K, Sabater-Lleal M, Ohrvik J, Bergendal A, Silveira A, Sundstrom A, Kieler H, Syvanen AC, Smith NL, Morange PE, Odeberg J, Hamsten A. Influence of coronary artery disease-associated genetic variants on risk of venous thromboembolism. Thrombosis research. 2014;134(2):426-32. https://doi.org/10.1016/j.thromres.2014.03.054 II. Bruzelius M, Bottai M, Sabater-Lleal M, Strawbridge RJ, Bergendal A, Silveira A, Sundstrom A, Kieler H, Hamsten A, Odeberg J. Predicting venous thrombosis in women using a combination of genetic markers and clinical risk factors. Journal of thrombosis and haemostasis. 2015;13:219-27. https://doi.org/10.1111/jth.12808 III. Bruzelius M, Ljungqvist M, Bottai M, Bergendal A, Strawbridge RJ, Holmstrom M, Silveira A, Kieler H, Hamsten A, Larfars G, Odeberg J. F11 is associated with recurrent VTE in women: A prospective cohort study. Thrombosis and Haemostasis. 2015 Oct 1;115(2). [Epub ahead of print] https://doi.org/10.1160/TH15-06-0459 IV. Bruzelius M, Iglesias MJ, Hong MG, Souto JC, Franberg M, Holmstrom M, Strawbridge RJ, Hamsten A, Uhlén M, Silveira A, Soria JM, Smadja DM, Butler L, Schwenk JM, Trégouët DA, Morange PE, Odeberg J. Identification of novel plasma biomarkers for venous thromboembolism: the VEREMA affinity proteomics study. 2015 [Manuscript]</p

    Erratum: Lack of immunity against rubella among Italian young adults. [BMC Infect Dis., 17, (2017) (199)] Doi: 10.1186/s12879-017-2295-y

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    After publication of this article [1], the authors noted that the given names and family names of all authors had been inverted, and are therefore incorrect in the original article. In the original article, the author names appear as the following: Gallone Maria Serena, Gallone Maria Filomena, Larocca Angela Maria Vittoria, Germinario Cinzia and Tafuri Silvio. However, this is incorrect, and the author names should appear as per the below: Maria Serena Gallone, Maria Filomena Gallone, Angela Maria Vittoria Larocca, Cinzia Germinario, Silvio Tafuri. The author names have been corrected in the author list and the citation for this Erratum

    Imagens de Otto Maria Carpeaux: esboço de biografia

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    Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas, Programa de Pós-Graduação em História, Florianópolis, 2015.Este esboço de biografia procura citar algumas imagens de Otto Maria Carpeaux: construções biográficas de naturezas múltiplas, elaboradas em contextos, por atores e sob condições igualmente díspares. Está constituído a partir de uma visão crítica da História, o que permite que ?outras imagens?, fragmentárias e não monumentais, também tenham espaço. Em diálogo com o princípio da montagem, este esboço apresenta-se em duas partes. Na primeira, Imagens possíveis, estão citadas as imagens elaboradas em vida e post mortem acerca do austríaco-brasileiro que nasceu em Viena em 1900, se exilou no Brasil em 1939 e morreu no Rio de Janeiro, em 1978. Na segunda, Montagens possíveis, apresentam-se duas possibilidades de exercício biográfico: pela leitura alegórica do documentário O velho e o Novo (Otto Maria Carpeaux), entendido como instrumento de intervenção no contexto ditatorial brasileiro e de uma reelaboração biográfica concernentes às suas experiências europeias; e pelo Caderno de imagens críticas, registro dos encontros em Carpeaux pelo meio de imagens críticas produzidas a partir da cesura do presente.Abstract : This biographical sketch attempts to quote some images of Otto Maria Carpeaux: various types of biographical constructions, carried out in different contexts by disparate authors under conditions just as distinct. It stems from a critical view of history, allowing for ?other images? fragmented and non-monumental ? to share the space.In dialogue with the montage principle, this sketch has two parts. The first, Possible Images, quotes the images produced during and after the life of the Austrian-Brazilian, who was born in Vienna in 1900, went to Brazil in exile in 1939 and died in Rio de Janeiro in 1978. The second part, Possible Montages, presents two possibilities of a biographical exercise: through the allegorical reading of documentary O Velho e o Novo (Otto Maria Carpeaux), understood as an instrument of intervention in the Brazilian dictatorship context and as a biographical retelling of the author?s European experiences; and through my Scrapbook of Critical Images, a record of the encounters in Carpeaux through critical images produced from the caesura of the present

    Maria José ao encontro de Tchekov

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    “A Carta da Corcunda para o Serralheiro” (“Letter from the Hunchback Girl to the Metalworker”), signed by Maria José, was first performed in a theatre show in 1988 (by actress-director Maria do Céu Guerra), two years before the typescript was published in book form for the first time by Teresa Rita Lopes. The evidence upon which this article is built is that it was the theatre that revealed the dramatic destination of this singular epistle of the only female heteronym that Fernando Pessoa invented, which was also the last heteronym to be created by the author. The dramatic construction of Maria José can be approximated to the character-building strategies in Anton Chekhov’s realist dramaturgy, in a way that differs from Pessoa’s other dramaturgical experiences. The analysis of Chekhov’s ascendancy over Stanislavski’s research, as well as the importance of Schopenhauer’s conception of the tragicomic, which is simultaneously projected onto Chekhov’s theatre and Maria José’s profile, are favourable lines of reading for this rapprochement between Pessoa and the Russian fiction writer and playwright. Pessoa’s readings of Chekhov’s texts (such as the play Uncle Vania and the short story “Vanka”) provide relevant data for assessing the magnitude of this encounter.“A Carta da Corcunda para o Serralheiro”, assinada por Maria José, começou por ser difundida num espectáculo de teatro em 1988 (pela actriz-encenadora Maria do Céu Guerra) dois anos antes de o dactiloscrito se ver publicado em livro, pela primeira vez, por Teresa Rita Lopes. Parte-se da evidência de ter sido o teatro a revelar a destinação dramática da epístola singular do único heterónimo mulher que Fernando Pessoa inventou, que terá sido também o último a ser criado pelo autor. A construção dramática de Maria José pode ser aproximada às estratégias de construção de personagem na dramaturgia realista de Anton Tchekov, de um modo que se distingue de outras experiências dramatúrgicas de Pessoa. A análise do ascendente de Tchekov sobre as pesquisas de Stanislavski, bem como a importância da concepção de tragicómico em Schopenhauer, que se projecta em simultâneo sobre o teatro de Tchekov e sobre o perfil de Maria José, são linhas de leitura propícias para esta aproximação entre Pessoa e o ficcionista e dramaturgo russo. As leituras de textos de Tchekov por parte de Pessoa (como o caso da peça Tio Vânia e o conto “Vanka”) fornecem dados relevantes para avaliar a magnitude deste encontro
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