470 research outputs found

    Supplemental material for Preoperative CT of cardiac veins for planning left ventricular lead placement in cardiac resynchronization therapy

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    Supplemental Figure for Preoperative CT of cardiac veins for planning left ventricular lead placement in cardiac resynchronization therapy by Hanna Markstad, Zoltan Bakos, Ellen Ostenfeld, Mats Geijer, Marcus Carlsson and Rasmus Borgquist in Acta Radiologica</p

    Tireless in His Service: Rasmus Andersen, Pastor and Author 1878-1924

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    Of the four founders of the Danish Lutheran Church in America in 1872, the one concerning whom the most information exists is Rasmus Andersen. Yet it has been my observation that comparatively little is known about him. A reason for this is that, to my knowledge, no comprehensive biography exists, and there is almost nothing available in the English language. Most of the material that does exist is to be found in the Danes World Wide Archives ( Udvandrerarkivet ) in Aalborg, Denmark. According to Birgit Flemming Larsen, who oversees that archive, the Andersen collection is the largest at the Aalborg archive. It consists of 104 archival boxes, filled with books, letters, diaries, memoirs, ministerial records, copies of letters sent, unpublished manuscripts and much more. The Danes World Wide Archives constitutes a treasure trove for the researcher who is interested in Rasmus Andersen

    Perehdytysopas Pirkanmaan saneerauspalvelu Oy:lle

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    Tämän opinnäytetyön tarkoituksena on perehdytysopas toimeksiantajayritys Pirkanmaan saneerauspalvelu Oy:n uusille työntekijöille. Yrityksellä ei ole aiemmin ollut perehdytysopasta työntekijöilleen, vaan uusien työntekijöiden perehdytys on toteutunut kokeneempien työntekijöiden toimesta työmailla. Lisäksi perehdytyksen yhteydessä yrityksen hallilla on pidetty perehdytyskierros, jolloin työnjohto on näyttänyt eri materiaalien sijainnit, kertonut lyhyesti yleisiä asioita yrityksestä ja työntekijän työtehtävistä. Tämän opinnäytetyön tavoitteena on, että jatkossa uusien työntekijöiden töiden aloittaminen on helpompaa sekä selkeämpää. Lisäksi tavoitteena on myös vähentää työnjohdon sekä kokeneempien työntekijöiden kuormitusta uusien työntekijöiden perehdyttämisessä. Opinnäytetyössä perehdyttämisen lisäksi työssä käsitellään rakennusalan työturvallisuutta, työsuoritteita ja niissä käytettäviä materiaaleja. Työssä tarkastellaan myös työkoneiden ja- välineiden turvallista käyttöä, Easoft-toiminnanohjausjärjestelmää sekä laadunvarmistukseen liittyviä asioita. Lopuksi pohditaan mahdollisia jatkotoimenpiteitä. Tämän perehdytysoppaan tekemiseen on kerätty tietoa kirjallisista lähteistä, haastateltu pitkään yrityksessä olleita ammattilaisia sekä tämän opinnäytetyön tekijän kokemuksia rakennusalalta. Tulevaisuudessa perehdytysopas on tarkoitus jakaa uusille työntekijöille (työsopimusta kirjoittaessa) sekä uusille vuokratyöntekijöille. Uusien työntekijöiden sekä vuokratyöntekijöiden tulee tutustua perehdytysoppaaseen ennen varsinaisten töiden aloitusta. Perehdytysopasta voidaan tulevaisuudessa muokata työnjohdon toimesta työntekijöiltä kerätyn palautteen perusteella. Lisäksi opasta muokataan, mikäli yrityksen toimintatavat ja työsuoritteet muuttuvat.The purpose of this thesis is an orientation guide for the new employees of the employer company Pirkanmaan Saneerauspalvelu Ltd. The company has not previously had an orientation guide for its employees, so the orientation of new employees has been implemented by more experienced workers in the workplace. In addition, during the orientation an induction tour has been held in the hall, where the supervisors have shown the locations of different materials, briefly told general things about the company and which tasks belong to whom. The objective of this thesis is to make it easier and clearer for the new employees to start working. In addition, the aim is to reduce the burden on supervisors as well as more experienced employees when orienting a new employee. In addition to orientation, this thesis deals with construction occupational safety, work processes and the materials used. The work also examines the safe use of machines and equipment used to work, ERP system called Easoft and issues regarding quality assurance. In the end potential follow-ups are pondered. To create this orientation guide information was collected from various written sources. In addition, professionals working in the company has been interviewed and the own experiences of the author of this thesis on the construction industry has been collected. In the future, the orientation guide will be distributed to new employees when writing an employment contract and also for new agency workers. The new employees as well as the agency workers should read the orientation guide before starting the actual work. In the future, the orientation guide can be modified by the management based on feedback from employees. In addition, the guide will be modified according to the changes of the company's policies and processes

    Coronary Heart Disease and Erectile Dysfunction

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    Coronary heart disease (CHD) is a common condition associated with a high mortality. There is now growing evidence that erectile dysfunction (ED) in men may be a suitable marker of sub-clinical cardiovascular disease, identifying patients at high risk for future CHD. We investigated the association between CHD risk factors and ED during a period of 25 years, in a population based cohort of men, aged 58-78 at follow-up. Risk factors were assessed at baseline and at study-end, and analyses were made in relation to ED prevalence at study end. ED evaluation was by the validated IIEF-5 questionnaire. We also examined if coronary endothelial and smooth muscle cell function was impaired, expressed as reduced coronary flow velocity reserve (CFVR), in otherwise healthy men with ED. CFVR in men with ED was compared to age-matched healthy controls and to men with diabetes or impaired fasting glucose. The results showed that: Men with ED had a reduced CFVR, independently of other risk factors for CHD. The magnitude of the CFVR reduction was similar in men with ED, as compared to men with diabetes or impaired fasting glucose. A number of classical CHD risk factors, identified at the baseline examination 25 years earlier, were associated with increased risk of ED. During the follow-up period, men with ED at study-end had a greater increase in fasting glucose levels, and were more likely to have developed the metabolic syndrome or diabetes, compared to men without ED. At study-end, several CHD risk factors including diabetes, low physical activity and low self rated health, were independently associated with ED. Furthermore, men with ED were more likely to be on antihypertensive and cholesterol-lowering medications at study-end. Our studies support the close epidemiological and pathophysiological links between ED and CHD. Men presenting with ED should be carefully evaluated for risk factors regarding CHD. Primary prevention can then be instituted, with modification of CHD risk factors, thus reducing future cardiovascular risk and in some cases simultaneously resulting in improvement of erectile function

    Bibliometric author evaluation through linear regression on the coauthor network

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    The rising trend of coauthored academic works obscures the credit assignment that is the basis for decisions of funding and career advancements. In this paper, a simple model based on the assumption of an unvarying “author ability” is introduced. With this assumption, the weight of author contributions to a body of coauthored work can be statistically estimated. The method is tested on a set of some more than five-hundred authors in a coauthor network from the CiteSeerX database. The ranking obtained agrees fairly well with that given by total fractional citation counts for an author, but noticeable differences exist

    Hemodynamic forces using 4D flow MRI: an independent biomarker of cardiac function in heart failure with left ventricular dyssynchrony?

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    Patients with heart failure with left ventricular (LV) dyssynchrony often do not respond to cardiac resynchronization therapy (CRT), indicating that the pathophysiology is insufficiently understood. Intracardiac hemodynamic forces computed from four-dimensional (4-D) flow MRI have been proposed as a new measure of cardiac function. We therefore aimed to investigate how hemodynamic forces are altered in LV dyssynchrony. Thirty-one patients with heart failure and LV dyssynchrony and 39 control subjects underwent cardiac MRI with the acquisition of 4-D flow. Hemodynamic forces were computed using Navier-Stokes equations and integrated over the manually delineated LV volume. The ratio between transverse (lateral-septal and inferior-anterior) and longitudinal (apical-basal) forces was calculated for systole and diastole separately and compared with QRS duration, aortic valve opening delay, global longitudinal strain, and ejection fraction (EF). Patients exhibited hemodynamic force patterns that were significantly altered compared with control subjects, including loss of longitudinal forces in diastole (force ratio, control subjects vs. patients: 0.32 vs. 0.90, P 0.05 for all). Hemodynamic forces by 4-D flow represent a new approach to the quantification of LV dyssynchrony. Diastolic force patterns separate healthy from diseased ventricles. Different force patterns in patients indicate the possible use of force analysis for risk stratification and CRT implantation guidance

    On estimating intraventricular hemodynamic forces from endocardial dynamics: A comparative study with 4D flow MRI

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    Intraventricular pressure gradients or hemodynamic forces, which are their global measure integrated over the left ventricular volume, have a fundamental importance in ventricular function. They may help revealing a sub-optimal cardiac function that is not evident in terms of tissue motion, which is naturally heterogeneous and variable, and can influence cardiac adaptation. However, hemodynamic forces are not utilized in clinical cardiology due to the unavailability of simple non-invasive measurement tools. Hemodynamic forces depend on the intraventricular flow; nevertheless, most of them are imputable to the dynamics of the endocardial flow boundary and to the exchange of momentum across the mitral and aortic orifices. In this study, we introduce a simplified model based on first principles of fluid dynamics that allows estimating hemodynamic forces without knowing the velocity field inside the LV. The model is validated with 3D phase-contrast MRI (known as 4D flow MRI) in 15 subjects, (5 healthy and 10 patients) using the endocardial surface reconstructed from the three standard long-axis projections. Results demonstrate that the model provides consistent estimates for the base-apex component (mean correlation coefficient r = 0.77 for instantaneous values and r = 0.88 for root mean square) and good estimates of the inferolateral-anteroseptal component (r = 0.50 and 0.84, respectively). The present method represents a potential integration to the existing ones quantifying endocardial deformation in MRI and echocardiography to add a physics-based estimation of the corresponding hemodynamic forces. These could help the clinician to early detect sub-clinical diseases and differentiate between different cardiac dysfunctional states

    Rasmus Sorensen and Danish Emigration, 1847-1863

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    Probably no individual played a more seminal role in the limited Danish emigration to North America before and during the Civil War than Rasmus Sorensen. From the late 1840s until the early 1860s this author, educator, politician, and social reformer led three groups of his countrymen to Wisconsin and, through numerous booklets, speeches, and letters encouraged others to settle elsewhere in the United States and Canada. Yet Sorensen has generally been little more than a supernumerary in the historiography of this transatlantic migration. Its pioneering historian, Peter Sorensen Vig, devoted twelve pages to him in his mammoth compendium, a dozen more than John Bille allowed him in his disjoint narrative of 1896. Arne Hall Jensen described Sorensen \u27s life in two paragraphs in 1937, giving various biographical details without interpreting their significance. There is little to indicate that the recent revival of interest in the Danish-American field will reverse this long tradition of neglect. In his monumental study of emigration from Denmark, Kristian Hvidt relates his activities in a scant paragraph, perhaps justifiably, because Sorensen \u27s lifespan fell completely outside Hvidt\u27s chronological framework
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