1,721,029 research outputs found
Zur Indikation, Methodik und Wertigkeit der immunhistologischen Diagnostik beim Hirninfarkt
Full text linkZur Indikation, Methodik und Wertigkeit der immunhistologischen Diagnostik beim Hirninfarkt
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Peripheral nervous system involvement in multiple sclerosis
No full textFragestellung:
Gibt es eine subklinische Beteiligung des peripheren Nervensystems bei Patienten mit Multipler Sklerose (MS) i) im Bereich der schnell leitenden Aα- und β-Fasern und/oder ii) im Bereich der langsam leitenden Aδ-Fasern?
Hintergrund:
Während die Standardneurographie bei Patienten mit MS in der Vergangenheit widersprüchliche Ergebnisse zeigte, konnten in elektrophysiologischen Repolarisationsstudien und histopathologischen Studien Hinweise auf eine subklinische Beteiligung des peripheren Nervensystems bei MS gefunden werden. Small Fiber Polyneuropathien sind in Kombination mit zahlreichen Autoimmunerkrankungen beschrieben, bei MS Patienten bisher jedoch nicht untersucht worden.
Patienten und Methoden:
Zur Diagnose von Neuropathien der Aα- und β-Fasern erfolgte bei 54 Patienten (43 mit schubförmigem, 11 mit sekundär progredientem Verlauf) eine Standardneurographie der Nn. tibiales, peronei und surales. Die Aδ-Fasern wurden bei 21 Patienten und 21 alters- und geschlechtsgematchten Kontrollprobanden mittels schmerzevozierter Potentiale (PREP) untersucht.
Ergebnisse:
Bei 29,6% (n=16) der untersuchten Patienten und 14,2% (n=23) aller untersuchten Nerven wurden ein oder mehrere pathologische Ergebnisse in der Standardneurographie gefunden. Die Messergebnisse der PREP unterschieden sich nicht zwischen Patienten- und Kontrollgruppe.
Diskussion:
Die gefundenen geringen Normwertabweichungen in der Standard-neurographie sprechen in Kombination mit den elektrophysiologischen und histopathologischen Vorstudien für eine subklinische Beteiligung des peripheren Nervensystems bei MS. Anzeichen für eine Small Fiber Polyneuropathie lagen nicht vor.Objective: To investigate possible peripheral nervous system (PNS) affection in patients with multiple sclerosis (MS) by standard nerve conduction velocity (SNC) and pain related evoked potentials (PREP), a novel electrophysiological method for diagnosing small fibre neuropathy. Background: Former neuropathological and electrophysiological studies demonstrated subtle PNS affection in MS, but routine measurements are mostly normal. Small fibre polyneuropathy is associated with several autoimmune diseases, but has not been investigated in MS yet. Design/Methods: Fifty-four MS patients (43 relapsing remitting, 11 secondary progressive MS; mean EDSS 2.58 ± 1.22, mean age 40.2 ± 8.2) underwent SNC of the tibial, sural and peroneal nerve. Twenty-one patients without evidence for spinal cord affection also underwent PREP. Results: 29.6% (n=16) of all patients and 14.2% (n=23) of all nerves examined showed at least one abnormal finding on SNC. No abnormalities on PREP were found. Conclusions/Relevance: We demonstrated subtle alterations on routine electrophysiological measurements in MS patients without clinical signs or symptoms for polyneuropathy
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