620 research outputs found
In the shadow of the church: the building of mosques in early medieval Syria
No full textIn his book In the Shadow of the Church: The Building of Mosques in Early Medieval Syria Mattia Guidetti examines the establishment of Muslim religious architecture within the Christian context in which it first appeared in the Syrian region, contributing to the debate on the transformation of late antique society to a Muslim one. He scrutinizes the slow process of conversion to Islam of the most important town centers by looking at religious places of both communities between the seventh and the eleventh century. The author assesses the relevancy of churches by analyzing the location of mosques and by researching phenomena of transfer of marble material from churches to mosques
Circadian clock as possible protective mechanism to pollution induced skin damage
No full textOzone is among the most toxic environmental stressors to which we are continuously exposed. Due to its critical location, skin is one of the most susceptible tissues to oxidative stress damaging effect of ozone. An increasing collection of data suggests a significant role of circadian system in regulation of cellular response to oxidative stress. However, the molecular mechanism linking circadian clock and antioxidant pathway it is not completely understood. Here we investigated a possible protective role of entrained circadian clock to ozone induced damage in keratinocytes, the main cellular component of human epidermis. Our results showed that, clock-synchronized keratinocytes compared to arrhythmic ones exhibited a more efficient antioxidant response, attested by a faster activation of the master antioxidant regulatory factor NRF2. Moreover, analysis of clock gene expression profiles reveals a more rapid induction of the cardinal clock gene Bmal1 in entrained cells. Based on these findings, we suppose that an adequate coordination of circadian system and antioxidant pathway might be essential to maintain homeostasis in the skin. Alteration of metabolic pathways occurred in neurological diseases or in irregular schedule of life activity could negatively influence tissue gene expression programs and associated organ physiology via its effect on the circadian system
RESVERATROL-INDUCED AUTOPHAGY CONTRIBUTES TO THE INHIBITION OF EPSTEIN BARR VIRUS REPLICATION IN BURKITT’S LYMPHOMA CELLS
No full textRESVERATROL-INDUCED AUTOPHAGY CONTRIBUTES TO THE INHIBITION OF EPSTEIN BARR VIRUS REPLICATION IN BURKITT’S LYMPHOMA CELLS
De Leo Alessandra (a), Colavita Francesca (a), Arena Giuseppe (b), Mattia Elena (a)
(a) Dip. di Scienze di Sanità Pubblica e Malattie Infettive “Sanarelli”, Univ. di Roma “Sapienza”
(b) Casa Sollievo della Sofferenza Hospital, CSS-Mendel Institute, Roma
Presenting author: De Leo Alessandra, [email protected]
We have previously examined the antiviral activity of resveratrol on the replication of Epstein Barr Virus (EBV), the etiologic agent of infectious mononucleosis and associated with several types of malignancies of epithelial and lymphoid origin.
In a cellular context that allows in vitro EBV activation and lytic cycle progression through mechanisms closely resembling those that in vivo initiate and enable productive infection, we found that RV inhibited EBV lytic genes expression and the production of viral particles in a dose-dependent manner
Does Independence Affect Regulatory Performance? The case of national competition authorities in the European Union
No full textDespite having always been assumed to be true, a relationship between the independence of regulatory agencies and their performance has never been formally tested. This paper aims at verifying whether formal regulatory independence affects the performance of national competition authorities in the EU member states. The author presents and discusses a statistical analysis which shows that greater formal independence leads competition authorities to investigate more cases and to issue more decisions
Caterina Colombini (1304 ca.-1387) o della cugina sedotta. Una ‘ricostruzione’ della figura di Caterina attraverso i testi letterari, in Le vestigia dei gesuati. L’eredità culturale del Colombini e dei suoi seguaci, a cura di I. Gagliardi, Firenze, Firenze University Press, 2020, pp. 57-71 ISBN 978-88-5518-227-0
No full textIn this essay the author demonstrates that it is possible to reconstruct the figure of Caterina Colombini (1340?-1387) – Giovanni Colombini's cousin – through a group of texts: the hagiography of Caterina, the letters sent to her by Giovanni Colombini and, finally, Giovanni's biography written by Feo Belcari. The author divides his text into four parts: the first part analyzes the content of Caterina's hagiography; the second examines the linguistic form of the hagiographic text; in the third, the author analyzes the latent meaning of the window, a symbolic place where Giovanni and Caterina converse on divine topics; in the last part, to conclude, the teachings that Giovanni gives to Catherine and her spiritual daughters – the Gesuate – are analyzed
La differenza italiana e l'aporetica del "non"
No full textIn this paper, the author discuss a recent volume on Antonio
Rosmini’s thought, and in particular around the relationship
between Rosmini and Fichte and the notion of nothingness and
nothingness of love
The album of Mattia De Rossi’s drawings. Projects for the Galleria Colonna ai Santi Apostoli
No full textThe study proposed here on Mattia De Rossi, a pupil of Gian Lorenzo Bernini and his most trusted collaborator, is part of an investigation that the author is doing on the figure of the architect, making use of an obvious investigative tool: his drawings.
In particular, the exceptional discovery of a bound volume of about 200 drawings of Mattia is a resource of great effectiveness for the study of his professional figure. Among the sheets of the collection, those relating to the construction site of the Galleria Colonna in the eponymous palace in Piazza SS. Apostoli in Rome, are presented.
These drawings explain the important contribution of Mattia and the creative process that led him to the definitive version of the central hall of the gallery. The drawings are also the only graphic documents related to the project of the Galleria Colonna, now only partially known through hypothetical reconstructions.
The case of the Palazzo Colonna is similar to other projects included in the volume, which enlighten us on De Rossi's career, and which explain his position in several important Roman buildings of the second half of seventeenth centur
A Choreographic Dialogue with Caribbean Poetry: The Sacredness of the Feminine in Walcott's Omeros (1990)
No full textThe aim of this paper is to show how the poetry and art of Caribbean writer Derek Walcott (1930-2017) tends to manifest and substantiate the desirable cultural transformation promoted by the work of the American anthropologist and scholar Riane Eisler. The recognition and the exaltation of symbols connected to the feminine world stand at the core of Walcott’s masterpiece Omeros. In a creative mutual dialogue between different genres and identities, the Caribbean author materialises Eisler’s attempts to forge a type of society based on a new partnership ethic. In a second perspective, this paper analyses how Walcott’s work opens the path to possible creative interdisciplinary approaches in the world of the arts. In my own contribution, as a professional dancer and choreographer, I have tried to “give voice” through movements to some episodes relating to the feminine included in Omeros
A Female Mystic and Educator in the Medici grand Duchy: Hagiography of the Venerable Leonora Ramirez de Montalvo (1602-1659) from medieval to modern topoi, in «Rivista di Storia e Letteratura religiosa», 2019/2020-a. 55, pp. 229-265 ISSN 0035-6573
No full textThis article aims to take into account the biography of the Venerable Leonora Ramirez de Montalvo (1602-1659) – mystic and educator in Florence of the Medici gran duchy – written by the jesuit father Cosimo de Pazzi. The author look at demonstrate the presence of medieval topoi and, at the same time, the presence of modern topoi. The whole representation has to be read in the frame of the baroque taste, in particular for the presence of the mystical visions
Competition policy enforcement in EU member states : what is independence for?
No full textThis book investigates the crucial EU policy of competition, which is enforced by the Commission and by national agencies that enjoy various degrees of autonomy from their governments. More and more policy-making activities are nowadays delegated to agencies that cannot be held accountable to parliaments, and ultimately to voters. The author explains why this is the case in the field of EU competition policy and discusses whether independence is linked to improved enforcement – as theories of delegation and common wisdom would suggest. These questions are explored with an in-depth analysis covering 27 EU countries for 17 years (1993–2009). While the results show that independence is given when countries lack credibility and good reputation, they also point out that autonomy from governments can hardly be associated with improved regulatory output. So, is independence of competition authorities useful to society in the end? This book will appeal to upper-level students and scholars interested in competition policy, regulatory agencies, and European public policy.1 Introduction -- 2 EU Competition Policy in Context -- 3 Independence: Reasons, Costs and Benefits -- 4 Explaining National Competition Authorities’ Independence -- 5 What Is Independence For? Measuring the Impact of Independence on Competition Policy Enforcement -- 6 ConclusionsPublished version of EUI PhD thesis, 201
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