30 research outputs found
Kemelimpahan artropoda pada ekosistem padi yang diberi mikoriza arbuskular, pupuk kandang dan npk
No full textUJI ADAPTASI VARIETAS UNGGUL PADI TADAH HUJAN KABUPEN JAYAPURA, PAPUA
Full text linkTeknologi budidaya dan penggunaan Varietas unggul merupakan salah satu komponen utama dalam meningkatkan produktivitas padi di lahan tadah hujan. Pengkajian bertujuan untuk mengevaluasi keragaan varietas unggul padi di lahan sawah tadah hujan yang dibudidayakan dengan pendekatan Pengelolaan tanaman terpadu (PTT). Kegiatan ini dilaksanakan di kampung Benyom Jaya 1 Distrik Nimbokrang Kabupaten Jayapura Provinsi Papua, pada bulan April sampai September 2017 menggunakan Rancangan Acak Kelompok (RAK) yang diulang sebanyak 4 kali. Varietas yang digunakan yaitu varietas unggul Inpari 7, Inpari 30, Inpari 32 dan Inpari 33, ditanam dalam petakan berukuran 3 ha. Luas petak percobaan untuk masing masing perlakuan adalah 20 x 20 m2 . Parameter yang dievaluasi meliputi : tinggi tanaman, jumlah anakan, komponen hasil dan serangan hama dan penyakit. Hasil kajian menunjukkan bahwa varietas Inpari 33 memberikan keragaan pertumbuhan dan hasil yang berbeda nyata dengan varietas Inpari 30, Inpari 7 dan Inpari 32. Varietas yang sesuai dan berdaya hasil tinggi di lokasi pengkajian adalah varietas produksi tinggi diperoleh dari varietas Inpari 33 (5,9 t/ha) dan terendah varietas Inpari 32 (4,47 t/ha)
Openbaring en ervaring, ’n reformatories-konfessionele benadering van 2 Petrus 1:16–21
Full text linkRevelation and experience, a reformed-confessional approach to 2 Peter 1:16–21. The experience of divine revelation is of crucial importance to the author of 2 Peter and in the age of the Reformation this notion was reflected in the way Guido de Brès used this epistle in the Belgic Confession. Both documents teach a divine authorship of Scripture with God as its responsible author and also that Scripture contains revelation of God that is accessible and authoritative for believers, even centuries after the lives of the prophets. In this process both documents recognise a dual interaction between holy Writ and the experience of the believer. The interaction with Scripture inspires trust in God and the work of the Spirit in the believer’s life inspires trust in holy Writ as God’s authoritative revelation
Aberrant neurodevelopment in human iPS cell-derived models of Alexander disease
Full text link23 p.-6 fig.Alexander disease (AxD) is a rare and severe neurodegenerative disorder caused by mutations in glial fibrillary acidic protein (GFAP). While the exact disease mechanism remains unknown, previous studies suggest that mutant GFAP influences many cellular processes, including cytoskeleton stability, mechanosensing, metabolism, and proteasome function. While most studies have primarily focused on GFAP-expressing astrocytes, GFAP is also expressed by radial glia and neural progenitor cells, prompting questions about the impact of GFAP mutations on central nervous system (CNS) development. In this study, we observed impaired differentiation of astrocytes and neurons in co-cultures of astrocytes and neurons, as well as in neural organoids, both generated from AxD patient-derived induced pluripotent stem (iPS) cells with a GFAPR239C mutation. Leveraging single-cell RNA sequencing (scRNA-seq), we identified distinct cell populations and transcriptomic differences between the mutant GFAP cultures and a corrected isogenic control. These findings were supported by results obtained with immunocytochemistry and proteomics. In co-cultures, the GFAPR239C mutation resulted in an increased abundance of immature cells, while in unguided neural organoids and cortical organoids, we observed altered lineage commitment and reduced abundance of astrocytes. Gene expression analysis revealed increased stress susceptibility, cytoskeletal abnormalities, and altered extracellular matrix and cell–cell communication patterns in the AxD cultures, which also exhibited higher cell death after stress. Overall, our results point to altered cell differentiation in AxD patient-derived iPS-cell models, opening new avenues for AxD research. © 2024 The Author(s). GLIA published by Wiley Periodicals LLC.This work was supported by grants from EJP RD COFUND-EJP Nº825575 Alexander to EMH, MP, MK, HA, and DPS and from la Caixa Foundation, Grant Agreement LCF/PR/HR21/52410002 to DPS,MP and EMH; grants from the Swedish Research Council (2017-02255, 2020-01148, and 2019-00284), ALF Gothenburg
(146051), The Swedish Society for Medical Research, Hjärnfonden (FO02021-0082), ALF (965939), Söderberg's Foundations, Hagströmer's Foundation Millennium, Amlöv's Foundation, and E. Jacobson's
Donation Fund to MP, and a mobility grant from the Swedish Foundation for Strategic Research (SM23-0033) to MK; grants from the Czech Science Foundation (24-11364S, 24-12028S) to LV, and Institutional support (RVO 86652036) to MK; grant from ZonMw 463002004 to EMH; grants from The Swedish Research Council,
Hjärnfonden and Petrus och Augusta Hedlunds stiftelse to HA,grants from MCIN/AEI/10.13039/501100011033 and “ERDF A way of making Europe” (PID2021-126827OB-I00) to DPS, and grants from X-Omics initiative (184.034.019) the Oncode Institute to CAGHVG and HRV; grants from the Swedish Society for Medical
Research to IC.Peer reviewe
Do Opposites Attract Divorce? Dimensions of Mixed Marriage and the Risk of Divorce in the Netherlands
Full text linkThe level of mixed marriage in a society indicates the openness of that society, since it shows the degree to which people from different social groups intermingle. In the Netherlands, mixed marriage once more attracts national attention because of the marriage between the Dutch Reformed Prince Willem-Alexander and the Catholic Argentinean Máxima Zorreguieta. Previous research has shown that, on average, spouses are quite similar with respect to social characteristics. Reasons for this phenomenon, known as homogamy, are sought in personal preferences and in preferences of the social environment such as parents and friends. The increasing rates of divorce make it both possible and interesting to focus on divorce. Do mixed marriages have a higher risk of ending up in divorce? The image of the openness of society will be extended and may have to be adapted, depending on the stability of mixed marriages. Couples can be mixed with regard to a number of social characteristics. Most of the limited research conducted on the relationship between mixed marriage and divorce only looked at one specific characteristic, or maybe a few, on which spouses may differ. In the present study, dimensions of six types of heterogamy are taken into account: regarding age, level of education, social status, religious affiliation, ethnicity and social origin. The author uses quantitative methods on two unique data sets: official marriage and divorce registrations and a survey among married and divorced people. In this way, he investigates the influence of mixed marriage on the risk of divorce in the Netherlands. Explanations for this influence, derived from the expected advantages of homogamy, are tested. Possible changes over the course of marriage and over time are investigated. The quality of spouse selection is assessed in the light of mixed marriage as well.
Do Opposites Attract Divorce? Dimensions of Mixed Marriage and the Risk of Divorce in the Netherlands
Full text linkThe level of mixed marriage in a society indicates the openness of that society, since it shows the degree to which people from different social groups intermingle. In the Netherlands, mixed marriage once more attracts national attention because of the marriage between the Dutch Reformed Prince Willem-Alexander and the Catholic Argentinean Máxima Zorreguieta. Previous research has shown that, on average, spouses are quite similar with respect to social characteristics. Reasons for this phenomenon, known as homogamy, are sought in personal preferences and in preferences of the social environment such as parents and friends. The increasing rates of divorce make it both possible and interesting to focus on divorce. Do mixed marriages have a higher risk of ending up in divorce? The image of the openness of society will be extended and may have to be adapted, depending on the stability of mixed marriages. Couples can be mixed with regard to a number of social characteristics. Most of the limited research conducted on the relationship between mixed marriage and divorce only looked at one specific characteristic, or maybe a few, on which spouses may differ. In the present study, dimensions of six types of heterogamy are taken into account: regarding age, level of education, social status, religious affiliation, ethnicity and social origin. The author uses quantitative methods on two unique data sets: official marriage and divorce registrations and a survey among married and divorced people. In this way, he investigates the influence of mixed marriage on the risk of divorce in the Netherlands. Explanations for this influence, derived from the expected advantages of homogamy, are tested. Possible changes over the course of marriage and over time are investigated. The quality of spouse selection is assessed in the light of mixed marriage as well
Do Opposites Attract Divorce? Dimensions of Mixed Marriage and the Risk of Divorce in the Netherlands
Full text linkThe level of mixed marriage in a society indicates the openness of that society, since it shows the degree to which people from different social groups intermingle. In the Netherlands, mixed marriage once more attracts national attention because of the marriage between the Dutch Reformed Prince Willem-Alexander and the Catholic Argentinean Máxima Zorreguieta. Previous research has shown that, on average, spouses are quite similar with respect to social characteristics. Reasons for this phenomenon, known as homogamy, are sought in personal preferences and in preferences of the social environment such as parents and friends. The increasing rates of divorce make it both possible and interesting to focus on divorce. Do mixed marriages have a higher risk of ending up in divorce? The image of the openness of society will be extended and may have to be adapted, depending on the stability of mixed marriages. Couples can be mixed with regard to a number of social characteristics. Most of the limited research conducted on the relationship between mixed marriage and divorce only looked at one specific characteristic, or maybe a few, on which spouses may differ. In the present study, dimensions of six types of heterogamy are taken into account: regarding age, level of education, social status, religious affiliation, ethnicity and social origin. The author uses quantitative methods on two unique data sets: official marriage and divorce registrations and a survey among married and divorced people. In this way, he investigates the influence of mixed marriage on the risk of divorce in the Netherlands. Explanations for this influence, derived from the expected advantages of homogamy, are tested. Possible changes over the course of marriage and over time are investigated. The quality of spouse selection is assessed in the light of mixed marriage as well
Do Opposites Attract Divorce? Dimensions of Mixed Marriage and the Risk of Divorce in the Netherlands
Full text linkThe level of mixed marriage in a society indicates the openness of that society, since it shows the degree to which people from different social groups intermingle. In the Netherlands, mixed marriage once more attracts national attention because of the marriage between the Dutch Reformed Prince Willem-Alexander and the Catholic Argentinean Máxima Zorreguieta. Previous research has shown that, on average, spouses are quite similar with respect to social characteristics. Reasons for this phenomenon, known as homogamy, are sought in personal preferences and in preferences of the social environment such as parents and friends. The increasing rates of divorce make it both possible and interesting to focus on divorce. Do mixed marriages have a higher risk of ending up in divorce? The image of the openness of society will be extended and may have to be adapted, depending on the stability of mixed marriages. Couples can be mixed with regard to a number of social characteristics. Most of the limited research conducted on the relationship between mixed marriage and divorce only looked at one specific characteristic, or maybe a few, on which spouses may differ. In the present study, dimensions of six types of heterogamy are taken into account: regarding age, level of education, social status, religious affiliation, ethnicity and social origin. The author uses quantitative methods on two unique data sets: official marriage and divorce registrations and a survey among married and divorced people. In this way, he investigates the influence of mixed marriage on the risk of divorce in the Netherlands. Explanations for this influence, derived from the expected advantages of homogamy, are tested. Possible changes over the course of marriage and over time are investigated. The quality of spouse selection is assessed in the light of mixed marriage as well
International Energy Technology Transfersfor Climate Change Mitigation - What, who, how, why, when, where, how much … and the Implications for International Institutional Architecture
Full text linkThe goal of the paper is to expand and refine the international technology transfer negotiating and analytic agendas and to reframe the issues. The paper presents concepts, indicators, illustrations and data that identify and measure international transfers of energy technologies that can be used to mitigate climate change. Among the questions on that agenda are how much technology transfer there has been to date, and how much will be needed in the future, especially to assist non-Annex I developing countries in their efforts to mitigate climate change. Before the how much questions can be answered, however, there are several prior questions, and hence the many other elements of the subtitle of the paper: what, who, how, why, when, where. These aspects of international technology transfer vary significantly among three existing institutional settings and among the associated analytic paradigms: North-South Official Development Assistance, Global Private International Investment and Trade, and International Public-Private Cooperation Agreements. The principal sections of the paper focus on features of international technology transfers in these institutional settings and on illustrations drawn from the biodiesel industry, especially the use of jatropha tree as the source of the feedstock. The conclusions are summarized as follows: (i) Technologies include intangible know-how and services, as well as tangible goods in the form of production process equipment and finished products. (ii) International transfers of some types of technology are much easier to measure than others. (iii) International technology transfers are highly industry-specific. (iv) Even for individual industries, it is necessary to use multiple indicators of technology transfers. (v) Patterns in the types of technology and methods of transfer vary across the three institutional settings examined in the paper. (vi) All three of the institutional arrangements are probably under-performing and inadequa
