197,033 research outputs found

    Local communities as sustainable tourism development partners

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    The Egyptian Strategic Tourism Development Plans are trying to play an increasingly important role in supporting the hoped-for transformation of Egypt’s undeveloped areas into world-class tourism destinations. The plans aim to add a considerable number of hotel rooms in the Red Sea region within the immediately forthcoming years. Particular natural features such as corals and other marine characteristics provide the main supply of revenue for locals, including fishermen; however they also constitute at the same time the core tourism attraction. Local people feel their land rights are being challenged by outsiders and threatened by planned tourism development of the area. They fear being cut off from traditional opportunities. Tourism development in the Red Sea region is characterized by the disregard of communities and illustrates the failure to improve local development and alleviation of poverty. This research investigated the relationship between mass-tourism development and local communities in the southern part of the Red Sea region. It has been undertaken to investigate barriers to change and assess means of promoting local communities involvement and evaluate roles and values of their participation. The study sought to clarify the conflicts between local communities and government which result from the tourism development structure, which has neglected locals’ rights. Consequently, the concept of sustainable tourism development (STD) and the interaction between tourism and environment, economy, society and culture are examined along with in depth analysis of the main characteristics influencing the host community. The investigation aims to understand the range of perception of tourism development stakeholders, so local communities, private sector parties, decision makers and tourism development facilitators such as consultants and NGOs have been investigated. Local communities’ opportunities, threats, strengths and weaknesses have been explored. Under the umbrella of STD a clear vision arises of the existing conditions surrounding local communities, not only in terms of their needs and their problems but also as a means to categorize local communities’ customs, intercultural and traditional life style. Recommendations aimed to secure improvements for local communities are discussed through explaining a rationale, standards, policy integration and roles for tourism development stakeholders. It is suggested that by promoting local communities’ key factors and using a community-based tourism approach in the study area, local people may be empowered and problems that hinder sustainability may be addressed

    Nuclear structure investigation of even–even and odd Pb isotopes by using the Hartree–Fock–Bogoliubov method

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    The nuclear structure of even–even and odd lead isotopes ([Formula: see text]Pb) is investigated within the Hartree–Fock–Bogoliubov (HFB) theory. Calculations are performed for a wide range of neutron numbers, starting from the proton-rich side up to the neutron-rich side, by using the SLy4 Skyrme interaction and a new proposed formula for the pairing strength which is more precise for this region of nuclei as we did in previous works in the regions of Neodymium (Nd, [Formula: see text]) [Y. El Bassem and M. Oulne, Int. J. Mod. Phys. E 24 (2015) 1550073] and Molybdenum (Mo, [Formula: see text]) [Y. El Bassem and M. Oulne, Nucl. Phys. A 957 (2017) 22]. Such a new pairing strength formula allows reaching exotic nuclei region where the experimental data are not available. Calculated values of various physical quantities such as binding energy, two-neutron separation energy, quadrupole deformation, and rms-radii for protons and neutrons are discussed and compared with experimental data and some estimates of other nuclear models like Finite Range Droplet Model (FRDM), Relativistic Mean Field (RMF) model with NL3 functional (NL3), Density-Dependent Meson-Exchange Relativistic Energy Functional (DD-ME2) and results of HFB calculations based on the D1S Gogny effective nucleon–nucleon interaction (Gogny D1S). </jats:p

    The amyloid precursor protein is a conserved Wnt receptor

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    The Amyloid Precursor Protein (APP) and its homologues are transmembrane proteins required for various aspects of neuronal development and activity, whose molecular function is unknown. Specifically, it is unclear whether APP acts as a receptor, and if so what its ligand(s) may be. We show that APP binds the Wnt ligands Wnt3a and Wnt5a and that this binding regulates APP protein levels. Wnt3a binding promotes full-length APP (flAPP) recycling and stability. In contrast, Wnt5a promotes APP targeting to lysosomal compartments and reduces flAPP levels. A conserved Cysteine-Rich Domain (CRD) in the extracellular portion of APP is required for Wnt binding, and deletion of the CRD abrogates the effects of Wnts on flAPP levels and trafficking. Finally, loss of APP results in increased axonal and reduced dendritic growth of mouse embryonic primary cortical neurons. This phenotype can be cell-autonomously rescued by full length, but not CRD-deleted, APP and regulated by Wnt ligands in a CRD-dependent manner.sponsorship: China Scholarship Council Tengyuan Liu Hersenstichting HS 2011(1)-46 Lee Fradkin Lebanese National Council for Scientific Research Maya Nicolas Vlaams Instituut voor Biotechnologie Bart De Strooper Bassem A Hassan Fondation Roger de Spoelberch 1911001IN Bassem A Hassan Agence Nationale de la Recherche ANR-10-IAIHU-06 Marie-Claude Potier Bassem A Hassan Fonds Wetenschappelijk Onderzoek G.0543.08 Bassem A Hassan Neuron-Glia Foundation 2003009NA Bassem A Hassan KU Leuven Methusalem Bart De Strooper Bassem A Hassan Nederlandse Organisatie voor Wetenschappelijk Onderzoek 40-00812-98-10058 Lee Fradkin Fonds Wetenschappelijk Onderzoek G.0680.10 Bassem A Hassan Fonds Wetenschappelijk On-G.0681.10 Bassem A Hassan derzoek Fonds Wetenschappelijk Onderzoek G.0503.12 Bassem A Hassan Agence Nationale de la Recherche ANR-11-INBS-0011-NeurATRIS Marie-Claude Potier Bassem A Hassan Agence Nationale de la Recherche ANR-12-MALZ-0004 Marie-Claude Potier Bassem A Hassan The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication. (China Scholarship Council, Hersenstichting|HS 2011(1)-46, Lebanese National Council for Scientific Research, Vlaams Instituut voor Biotechnologie, Fondation Roger de Spoelberch|1911001IN, Agence Nationale de la Recherche|ANR-10-IAIHU-06, Agence Nationale de la Recherche|ANR-11-INBS-0011-NeurATRIS, Agence Nationale de la Recherche|ANR-12-MALZ-0004 Marie-Claude, Fonds Wetenschappelijk Onderzoek|G.0543.08, Fonds Wetenschappelijk Onderzoek|G.0680.10, Fonds Wetenschappelijk Onderzoek|G.0503.12, Neuron-Glia Foundation|2003009NA, KU Leuven, Nederlandse Organisatie voor Wetenschappelijk Onderzoek|40-00812-98-10058, Medical Research Council|UKDRI-1004)status: Publishe

    Biological responses of white sea bream (Diplodus sargus, Linnaeus 1758) and sardine (Sardine pilchardus, Walbaum 1792) exposed to heavy metal contaminated water

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    The aim of the present work was to assess, by rapid approach, the detoxification capacity and the genotoxicity caused by exposure of some marine fish to polluted waters. The fish species selected for the study: White sea bream (Diplodus sargus, Linnaeus 1758) and sardine (Sardine pilchardus, Walbaum 1792) were collected from different sites of Alexandria, El-Max bay and Bahary, in Egypt. Results of heavy metals analysis in sediment were: Al>Fe>Cr>Pb>Hg>Cd. Concerning detoxification analysis, fish collected from El-Max bay encounter the highest liver enzyme activity of Glutathione S-Transferase. Also, genotoxicity was evaluated in liver, gills and muscle of fishes collected and the results indicated that fish collected from El-Max bay has the highest levels of comets (DNA damage) when compared to the other sites selected as reference. It can be concluded from our results that the different tissues examined have alteration of level of detossification and comets as result of different degree of oxidative pollution insult. These biological responses may be considered for rapid extimation of food oxidative damage as well as for environmental quality

    Dr. Duane M. Jackson, Morehouse College, July 2011

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    This video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer

    "Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.

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    "Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states. By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement. To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports

    Supplemental material for Informing efficient pilot development of animal trauma models through quality improvement strategies

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    Supplemental material for Informing efficient pilot development of animal trauma models through quality improvement strategies by Penny S Reynolds, Jacquelyn McCarter, Christopher Sweeney, Bassem M Mohammed, Donald F. Brophy, Bernard Fisher, Erika J Martin and Ramesh Natarajan in Laboratory Animals</p

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Dr. Glendon Swarthout

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    Hosted by Roger M. Busfield, MSU Assistant Professor of Speech and Theater, Meet the Author is designed to introduce a general audience to a contemporary author and their work through in-depth interviews. This episode features a conversation between Dr. Glendon Swarthout, prolific author and English professor at MSU, and assistant professors Sam S. Baskett and Theodore B. Strandness

    Simulation of thermal plant optimization and hydraulic aspects of thermal distribution loops for large campuses

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    Following an introduction, the author describes Texas A&M University and its utilities system. After that, the author presents how to construct simulation models for chilled water and heating hot water distribution systems. The simulation model was used in a $2.3 million Ross Street chilled water pipe replacement project at Texas A&M University. A second project conducted at the University of Texas at San Antonio was used as an example to demonstrate how to identify and design an optimal distribution system by using a simulation model. The author found that the minor losses of these closed loop thermal distribution systems are significantly higher than potable water distribution systems. In the second part of the report, the author presents the latest development of software called the Plant Optimization Program, which can simulate cogeneration plant operation, estimate its operation cost and provide optimized operation suggestions. The author also developed detailed simulation models for a gas turbine and heat recovery steam generator and identified significant potential savings. Finally, the author also used a steam turbine as an example to present a multi-regression method on constructing simulation models by using basic statistics and optimization algorithms. This report presents a survey of the author??s working experience at the Energy Systems Laboratory (ESL) at Texas A&M University during the period of January 2002 through March 2004. The purpose of the above work was to allow the author to become familiar with the practice of engineering. The result is that the author knows how to complete a project from start to finish and understands how both technical and nontechnical aspects of a project need to be considered in order to ensure a quality deliverable and bring a project to successful completion. This report concludes that the objectives of the internship were successfully accomplished and that the requirements for the degree of Degree of Engineering have been satisfied
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