83 research outputs found
An exploration of the cultural context and consequences of perceptions of illness and health-seeking behaviour of the Baloch
No full textHuman beliefs about health and illness structure the explanations for health and illness in a society and these explanations rationalise preventive or therapeutic strategies. The purpose of this research was to discover, identify and understand the perceptions of health, illness and health seeking behaviour of the Baloch people in a cultural perspective. More specifically, it was to document their perception regarding the origin and cause of illness and disease as revealed in their system of disease-classification and their etiological categories. It was also to describe the context in which Baloch access the traditional health care system as well as conventional health care. Participant observations and in-depth interviews were the tools for data collection in this ethnographic study. Four districts of Pakistani Balochistan were selected for fieldwork. Traditional or folk healers of different categories, medical professionals, sufferers, family heads, community elders, tribal chiefs and medical doctors were interviewed in depth during fieldwork and many socio-cultural phenomena and ritual healing practices were participated in and observed. It was observed that Baloch beliefs regarding health and illness revolve either on the concept of natural causes that are mainly due to humoral imbalance or supernatural causes: spirit possession, sorcery or evil eye. In contemporary Balochistan, despite the availability of the basic health care system in the majority of Baloch settlements, for all practical purposes, Baloch use their traditional medical practices alongside biomedicine. These medical practices mainly consist of herbal remedies and spiritual healing practices. Folk medical beliefs are inseparable from other elements of Baloch cultural life and in this context health planners and medical practitioners in Balochistan, mutually can do much to balance and integrate biomedicine and folk and traditional medicine. Working together, they can optimise the benefits for their client populations
Perineal healing following abdominoperineal excision for rectal and anal cancer
No full textAbdominoperineal rectal excision (APE) may be indicated for distal rectal cancer and anal cancer patients. For many patients the extralevator APE (ELAPE) technique in which a larger part of the pelvic floor is removed is commonly used currently. Most patients in whom an APE is performed have received radiotherapy (RT) preoperatively. Perineal healing disorders after APE occur with high frequency and various techniques and measures may be attempted to improve healing rates. Healing disorders create problems for patients and health care systems, but less is known on the possible oncological impact.Paper I aimed to evaluate perineal healing following ELAPE in patients with perineal reconstruction using a biological mesh. A retrospective single center study of 88 consecutive ELAPE patients between 2011 and 2015 was performed. Three different types of biological mesh were used for perineal reconstruction. 97% of patients had received radiotherapy and 62% had an omentoplasty. Healing rates of 66% and 92% at 3 and 12 months, respectively, were observed. No association was found between examined variables and healing rate at 3 months. Biological mesh for perineal reconstruction following ELAPE is considered feasible and safe.Paper II aimed to evaluate whether simultaneous perineal reconstruction and parastomal reinforcement with the biological mesh Strattice™ after ELAPE could prevent hernia formation. In a prospective multicenter design, 19 patients were recruited between July 2013 and August 2014. Patients were assessed for perineal and parastomal wound healing on postoperative day 7 and at 1, 3, 6 and 12 months. CT and/or dynamic MRI at one year was used to detect perineal hernia and CT for parastomal hernia. Three parastomal and no perineal hernias were detected. At one year all perineal and parastomal wounds were healed.The objective of Paper III was to evaluate perineal healing in relation to ERAS compliance, type of resection and method of perineal reconstruction in patients with squamous cell carcinoma of the anus (SCCA) after salvage surgery. Between 2005 and 2015, 101 patients (67 women), in the Stockholm-Gotland region were included. Surgery was performed at two hospitals and ERAS compliance was 71%. 58 patients underwent APE and 43 pelvic exenteration. Perineal reconstruction was by primary closure (39 patients), gluteal myocutaneus flap (31 patients) and vertical rectus abdominis myocutaneou flap (31 patients). Healing at 3 months was achieved in 61 patients and was significantly associated with age and type of perineal reconstruction. At one year, 84 of 89 surviving patients had a healed perineal wound.In Paper IV, the cohort from Paper III was examined with respect to impact of perineal healing on survival. Following exclusion, 95 patients constituted the study cohort. Healing status at 90 days postoperatively was used as a landmark. R0 was achieved in 93% and overall survival (OS) at 5 years was 61%. In the univariable analysis, an unhealed wound at landmark date was significantly associated with OS and recurrence free survival (RFS) showed a similar relationship (p=0.054, log rank). However, in the multivariable analyses only non-significant trends were indicated.List of scientific papersI. Baloch N, Nilsson PJ, Nordenvall C, Abraham-Nordling M. Perineal wound closure using biological mesh following extra-levator abdominoperineal excision. Digestive Surgery. 2019; 36(4): 281-288. https://doi.org/10.1159/000489134 II. Aslam MI, Baloch N, Mann C, Nilsson PJ, Maina P, Chaudri S, Singh B. Simultaneous stoma reinforcement and perineal reconstruction with biological mesh – a multicenter prospective observational study. Annals of Medicine and Surgery. 2018; 38: 28-33. https://doi.org/10.1016/j.amsu.2018.12.006 III. Baloch N, Nordenvall C, Johansson H, Nygren J, Nilsson PJ. Perineal healing following salvage surgery for anal cancer. Colorectal Disease. 2021; 23(5): 1102-1108. https://doi.org/10.1111/codi.15496 IV. Baloch N, Nygren J, Nordenvall C, Abraham-Nordling M, Lagerbäck C, Mikael Machado, Nilsson PJ. Impact of perineal healing on oncological outcome following surgery for squamous cell carcinoma of the anus. [Manuscript]</p
میر گل خان نصیر بطور محقق: ایک جائزہ
No full textThis article provides a comprehensive overview of the life and contributions of Mir Gul Khan Naseer, a prominent figure in Balochi literature, research, and history. Mir Gul Khan Naseer, born in 1914, is widely recognized as a prolific poet, writer, and scholar of the Balochi language, as well as a passionate advocate for the rights and preservation of Baloch culture and heritage.
Furthermore, the article delves into Mir Gul Khan Naseer's literary achievements, showcasing his profound impact on Balochi literature. Moreover, his contributions as a historian shed light on Baloch history, culture, and traditions, ensuring their preservation for future generations.
The article also explores Mir Gul Khan Naseer's role as a researcher and his commitment to scholarly pursuits. He conducted extensive research on various aspects of Baloch culture, literature, and history, authoring numerous books and scholarly papers. His scholarly endeavors contributed significantly to the understanding and appreciation of Baloch heritage, making him a revered figure among academics and researchers.
Overall, this article provides a concise yet comprehensive overview of Mir Gul Khan Naseer’s literary achievements, and scholarly contributions. It aims to highlight his invaluable contributions to Balochi literature, research, and historiography, ensuring that his legacy as a researcher and historian continues to inspire and educate future generations
Digital Lipoma of The Big Toe in Child: A Rare Case Report
No full textA lipoma is a typical non-cancerous soft tissue lump that can develop beneath the skin and may grow anywhere in the body most commonly involving the upper trunk (chest, arm, shoulder, neck and upper thigh). They grow slowly and are non-cancerous. While lipomas in the foot are relatively uncommon, their occurrence in this location is rare. To our knowledge lipoma of the toe in a child is a very rare case. This case study concerns a large lipoma in a child, specifically located on the underside of the first big toe, its radiological imaging finding on ultrasound and histopathology
The Study of Fixed Point Theory for Various Multivalued Non-Self
No full textKARAPINAR, ERDAL/0000-0002-6798-3254; Shahzad, Naseer/0000-0001-7155-5917The basic motivation of this paper is to extend, generalize, and improve several fundamental results on the existence (and uniqueness) of coincidence points and fixed points for well-known maps in the literature such as Kannan type, Chatterjea type, Mizoguchi-Takahashi type, Berinde-Berinde type, Du type, and other types from the class of self-maps to the class of non-self-maps in the framework of the metric fixed point theory. We establish some fixed/coincidence point theorems for multivalued non-self-maps in the context of complete metric spaces.National Science Council of the Republic of China [NSC 101-2115-M-017-001]The first author was supported partially by grant no. NSC 101-2115-M-017-001 of the National Science Council of the Republic of China
Spectroscopic (FT-IR, Raman, NMR and UV-vis.) and quantum chemical investigations of (E)-3-[4-(pentyloxy)phenyl]-1-phenylprop-2-en-1-one
No full textGokce, Halil/0000-0003-2258-859X; Naseer, Muhammad Moazzam/0000-0003-2788-2958WOS: 000342254500042In this study, the molecular structure and vibrational and electronic transition spectra and H-1 and C-13 NMR chemical shift values (gas phase and in chloroform solvent), HOMO-LUMO analysis, molecular electrostatic potential (MEP), thermodynamic properties and Mulliken atomic charges of (E)-344-(pentyloxy)phenyl]-1-phenylprop-2-en-1-one molecule, C20H22O2, which has many biological activities have been calculated using the DFT/B3LYP method with 6-311++G(d,p) basis set in the ground state. The obtained results indicate a good harmony among the calculated and the experimental FT-IR, Raman, UV vis. (in methanol solvent) and H-1 and C-13 NMR (in chloroform-d solvent) spectra of the mentioned compound. (C) 2014 Elsevier B.V. All rights reserved.Higher Education Commission of PakistanHigher Education Commission of PakistanThe author AA is grateful to Higher Education Commission of Pakistan for financial support
Analytic continuation of dimensions in supersymmetric localization
No full textWe compute the perturbative partition functions for gauge theories with eight supersymmetries on spheres of dimension d ≤ 5, proving a conjecture by the second author. We apply similar methods to gauge theories with four supersymmetries on spheres with d ≤ 3. The results are valid for non-integer d as well. We further propose an analytic continuation from d = 3 to d = 4 that gives the perturbative partition function for an N =1 gauge theory. The results are consistent with the free multiplets and the one-loop β-functions for general N = 1 gauge theories. We also consider the analytic continuation of an N = 1 preserving mass deformation of the maximally supersymmetric gauge theory and compare to recent holographic results for N = 1[superscript ∗] super Yang-Mills. We find that the general structure for the real part of the free energy coming from the analytic continuation is consistent with the holographic results. Keywords: Extended Supersymmetry, Matrix Models, Supersymmetric Gauge TheoryUnited States. Department of Energy (Contract de-sc0012567
CVEfixes: Automated Collection of Vulnerabilities and Their Fixes from Open-Source Software
No full textCVEfixes is a comprehensive vulnerability dataset that is automatically collected and curated from Common Vulnerabilities and Exposures (CVE) records in the public U.S. National Vulnerability Database (NVD). The goal is to support data-driven security research based on source code and source code metrics related to fixes for CVEs in the NVD by providing detailed information at different interlinked levels of abstraction, such as the commit-, file-, and method level, as well as the repository- and CVE level.
At the initial release, the dataset covers all published CVEs up to 9 June 2021. All open-source projects that were reported in CVE records in the NVD in this time frame and had publicly available git repositories were fetched and considered for the construction of this vulnerability dataset. The dataset is organized as a relational database and covers 5495 vulnerability fixing commits in 1754 open source projects for a total of 5365 CVEs in 180 different Common Weakness Enumeration (CWE) types. The dataset includes the source code before and after fixing of 18249 files, and 50322 functions. Because of limitations in GitHub storage, we provide a compressed SQL dump of the CVEfixes vulnerability dataset via Zenodo with DOI: 10.5281/zenodo.4476563.
This repository includes the code to replicate the data collection. The complete process has been documented in the paper "CVEfixes: Automated Collection of Vulnerabilities and Their Fixes from Open- Source Software", a copy of which you will find in the Doc folder.
Citation and Zenodo links
Please cite this work by referring to the published paper:
Guru Bhandari, Amara Naseer, and Leon Moonen. 2021. CVEfixes: Automated Collection of Vulnerabilities and Their Fixes from Open-Source Software. In Proceedings of the 17th International Conference on Predictive Models and Data Analytics in Software Engineering (PROMISE '21). ACM, 10 pages. https://doi.org/10.1145/3475960.3475985
@inproceedings{bhandari2021:cvefixes,
title = {{CVEfixes: Automated Collection of Vulnerabilities and Their Fixes from Open-Source Software}},
booktitle = {{Proceedings of the 17th International Conference on Predictive Models and Data Analytics in Software Engineering (PROMISE '21)}},
author = {Bhandari, Guru and Naseer, Amara and Moonen, Leon},
year = {2021},
pages = {10},
publisher = {{ACM}},
doi = {10.1145/3475960.3475985},
copyright = {Open Access},
isbn = {978-1-4503-8680-7},
language = {en}
}
The dataset has been released on Zenodo with DOI:10.5281/zenodo.4476563. The GitHub repository containing the code to automatically collect the dataset can be found at https://github.com/secureIT-project/CVEfixes, released with DOI:10.5281/zenodo.5111494.This work has been financially supported by the Research Council of Norway through the secureIT project (RCN contract #288787)
Formulation for the Targeted Delivery of a Vaccine Strain of Oncolytic Measles Virus (OMV) in Hyaluronic Acid Coated Thiolated Chitosan as a Green Nanoformulation for the Treatment of Prostate Cancer: A Viro-Immunotherapeutic Approach [Retraction]
No full textNaseer F, Ahmad T, Kousar K, et al. Int J Nanomedicine. 2023;18:185–205.
We, the Editor and Publisher of the journal International Journal of Nanomedicine are retracting the published article.
Following publication of the article, concerns were raised about the duplication of images from Figures 8, 10 and 13 with images from other unrelated articles. Specifically,
The image for Figure 8A, blank NF temperatures, has been duplicated with the image for Figure 13C, SEM of lyophilized NF after 3 months storage.
The image for Figure 8C, HA-coated OMV loaded TC, has been duplicated with the image for Figure 16C, lyophilized NFs after 3 months, from Kousar K, Naseer F, Abduh MS, Anjum S and Ahmad T. CD44 targeted delivery of oncolytic Newcastle disease virus encapsulated in thiolated chitosan for sustained release in cervical cancer: a targeted immunotherapy approach. Front. Immunol. 2023;14:1175535. https://doi.org/10.3389/fimmu.2023.1175535.
The image for Figure 8D, HA-coated OMV loaded TCs, has been duplicated with the image for Figure 6B, CsA-loaded ThC-HA NF, from Abduh MS. Anticancer Analysis of CD44 Targeted Cyclosporine Loaded Thiolated Chitosan Nanoformulations for Sustained Release in Triple-Negative Breast Cancer. Int J Nanomedicine. 2023;18:5713-5732. https://doi.org/10.2147/IJN.S424932.
The image for Figure 9D, HA-coated OMV-loaded TCs, has been duplicated with the image for Figure 10B, HA-ThCs-Cis NFs, from Kousar K, Naseer F, Abduh MS, et al. Green synthesis of hyaluronic acid coated, thiolated chitosan nanoparticles for CD44 targeted delivery and sustained release of Cisplatin in cervical carcinoma. Front. Pharmacol. 2023;13:1073004. https://doi.org/10.3389/fphar.2022.1073004.
The entire Figure 10 has been duplicated with Figure 6 from Naseer F, Kousar K, Abduh MS, et al. Evaluation of the anticancer potential of CD44 targeted vincristine nanoformulation in prostate cancer xenograft model: a multi-dynamic approach for advanced pharmacokinetic evaluation. Cancer Nano. 2023;14:65. https://doi.org/10.1186/s12645-023-00218-2.
The images for Figure 10, Pure MV 12h, 90µg/ml and OMV-loaded TCs 24h, 50µg/ml have been duplicated.
The image for Figure 10, OMV-loaded TCs 24h, 90µg/ml has been duplicated with the image for Figure 10, MCF-10A, Pure CsA, 90µg/ml from Abduh MS, 2023.
The image for Figure 10, Pure MV 12h, 50µg/ml has been duplicated with the image for Figure 10, MCF-10A, CsA-NF, 60µg/ml from Abduh MS, 2023.
The images for Figure 13C, lyophilized NF after 3 months storage, has been duplicated with the image for Figure 7A, SEM image of spherical HA-ThCs-Cis loaded nanoparticles, from Kousar K, et al (2023).
The corresponding author responded to our queries but was unable to provide a satisfactory explanation for how the images came to be duplicated and the editor no longer has confidence in the reported findings. As verifying the validity of published work is core to the integrity of the scholarly record, the Publisher and Editor requested to retract the article and the corresponding author does not agree with this decision.
We have been informed in our decision-making by our editorial policies and COPE guidelines.
The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”
Retraction Note: Refining Parkinson’s neurological disorder identification through deep transfer learning (Neural Computing and Applications, (2020), 32, 3, (839-854), 10.1007/s00521-019-04069-0)
No full textThe Editor-in-Chief and the publisher have retracted this article. The article was submitted to be part of a guest-edited issue. An investigation by the publisher found a number of articles, including this one, with a number of concerns, including but not limited to compromised editorial handling and peer review process, inappropriate or irrelevant references or not being in scope of the journal or guest-edited issue. Based on the investigation's findings the Editor-in-Chief therefore no longer has confidence in the results and conclusions of this article. The authors Imran Razzak and Saeeda Naz disagree with this retraction. The author Muhammad Imran has not responded to correspondence regarding this retraction. The Publisher has not been able to obtain a current email address for the authors Amina Naseer, Monail Rani, and Guandong Xu
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