3,144 research outputs found
Austerität, das italienische Gesundheitssystem und die Corona-Krise
No full textFranz Prante, Alessandro Bramucci, Achim TrugerLiteraturverzeichnis Seite 25-2
The governance of offshoring and its effects at home: The role of codetermination in the international organization of German firms
No full textThis paper focuses on the links between labor market institutions and offshoring, with specific reference to the role of codetermination in shaping the international operations of German firms. We use case studies to illustrate how works councils deal with three important aspects of offshoring processes: the timeliness of information they receive from the management, the negotiation of compensation mechanisms and the design of alternative strategies. While we found no evidence of works councils impeding offshoring, there are elements to suggest that they may influence the way such decisions are taken, and moderate their effects on employment in the home country
The governance of offshoring and its effects at home.The role of codetermination in the international organization of German firms
No full textThis paper focuses on the links between labor market institutions and
offshoring, with specific reference to the role of codetermination in shaping the
international operations of German firms. We use case studies to illustrate how
works councils deal with three important aspects of offshoring processes: the
timeliness of information they receive from the management, the negotiation of
compensation mechanisms, and the design of alternative strategies. While we found
no evidence of works councils impeding offshoring, there are elements to suggest
that they may influence the way such decisions are taken and moderate their effects
on employment in the home country
PyMod: a tool for the analysis of protein structures and sequences in PyMOL
No full textIn recent years, an exponential growing number of tools for protein sequence analysis, editing and modelling tasks have been put at the disposal of the scientific community. Despite the vast majority of these tools have been released as open source software, their deep learning curves often discourages even the most experienced users. For example, in the earlier stages of protein modeling by homology means, the lack of user-friendly Graphical User Interfaces (GUIs), the need to make use of many programs in an integrated way, Input and Output file format problems, and platform-dependent installation
dependencies, often lead to submition of homology modelling tasks to automatic online servers, with no or poor chances to apply human knowledge and experience in the key-steps required to yield a good model.In order to tackle this issue, a simple and intuitive interface, PyMOD, between the popular
molecular graphics system PyMOL and several other tools (i.e., BLAST, ClustalW, CEalign and Modeller) has been developed, to show how the integration of the individual
steps required for homology modelling and sequence/structure analysis inside PyMOL can hugely simplify these tasks. PyMOD was developed with an emphasis on ease of use and full customization of the parameters of all the algorithms used for analysis. Database searches, multiple sequence and structural alignments generation and editing, and even the possibility to mix sequence and structure alignments have been implemented in PyMod, with the aim of creating a simple, yet powerful tool for preliminary analysis and building of homology models
PyMod: sequence similarity searches, multiple sequence-structure alignments, and homology modeling within PyMOL
No full textBackground: In recent years, an exponential growing number of tools for protein sequence analysis, editing and modeling tasks have been put at the disposal of the scientific community. Despite the vast majority of these tools have been released as open source software, their deep learning curves often discourages even the most experienced users. Results: A simple and intuitive interface, PyMod, between the popular molecular graphics system PyMOL and several other tools (i.e., [PSI-] BLAST, ClustalW, MUSCLE, CEalign and MODELLER) has been developed, to show how the integration of the individual steps required for homology modeling and sequence/structure analysis within the PyMOL framework can hugely simplify these tasks. Sequence similarity searches, multiple sequence and structural alignments generation and editing, and even the possibility to merge sequence and structure alignments have been implemented in PyMod, with the aim of creating a simple, yet powerful tool for sequence and structure analysis and building of homology models. Conclusions: PyMod represents a new tool for the analysis and the manipulation of protein sequences and structures. The ease of use, integration with many sequence retrieving and alignment tools and PyMOL, one of the most used molecular visualization system, are the key features of this tool. Source code, installation instructions, video tutorials and a user's guide are freely available at the URL http://schubert.bio.uniroma1.it/pymod/index.htm
A imagem de Alessandro Baricco no Brasil
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão, Programa de Pós-Graduação em Estudos da Tradução, Florianópolis, 2013.Com a intenção de delinear o modo pelo qual o escritor italiano Alessandro Baricco se inseriu no sistema literário brasileiro e os caminhos percorridos pelos seus livros traduzidos, esta dissertação dá voz às experiências tradutórias de seus tradutores. A inserção de Bariccono Brasil tem seu início em 1997, através de uma proposição da Profa. Dra. Roberta Barni à editora Iluminuras da tradução de Oceano Mare. A partir daí, outras sete obras foram publicadas no Brasil, sendo três delas traduzidas por Roberta Barni e as outras quatro por quatro tradutores diferentes. De um lado, considera-se o tradutor como figura principal namediação entre culturas, e, de outro, se analisa a realidade desta figuradentro do sistema literário, sua invisibilidade, seus limites e o exercíciode sua profissão. A pesquisa conta, ainda, com críticas e resenhas referentes ao autor italiano publicadas em jornais consagrados no Brasil, considerando estas como parte constituinte da imagem de Baricco refletida em território nacional. Abstract : Intending to delineate the way the Italian writer Alessandro Baricco has been inserted in the Brazilian literary system and the paths his translated books have followed, this thesis gives voice to the translating experiences of his translators. Baricco's insertion in Brazil began in 1997, through a personal project of Dr. Roberta Barni, with her translation of Oceano Mare. Since then, seven other of his works have been published in Brazil, three of which were translated by Roberta Barni and the other four by four different translators. On the one hand,the translator is considered as the main figure in mediation betweencultures and, on the other, this figure's reality is analyzed within theliterary system: its invisibility, its limits and its professional practice. Criticisms and reviews of this Italian author published in well established Brazilian newspapers are also considered, with the understanding that they are part of Baricco's image reflected here
Offshoring, industry heterogeneity and employment
No full textEconomies and production systems are subject to incessant processes of structural change
fuelled by the dynamics of demand, technology and international competition. The
increasing international fragmentation of production, also known as “offshoring”, is an
important element of such a (global in scale) process of structural change having
important implications for employment and on the way employment gains and losses are
distributed across firms, industries, national economies and components of the labour
force. This paper assesses the employment impact of offshoring, in five European
countries (Germany, Spain, France, Italy and the United Kingdom), distinguishing
between different types of inputs/tasks offshored, different types of offshoring industries
and types of professional groups affected by offshoring. Results provide a rather
heterogeneous picture of both offshoring patterns and their effects on labour, and the
presence of significant differences across industries. Along with this variety of
employment outcomes, the empirical evidence suggests that offshoring activities are
mainly driven by a cost reduction (labour saving) rationale. This is particularly the case
for the manufacturing industry where offshoring is found to exert a negative impact
among the less qualified (manual) or more routinized (clerks) types of jobs, while the
main difference between high- and low-technology industries has to do with the type of
labour tasks that are offshored and the types of domestic jobs that are affected. In hightech
industries the negative effects of offshoring on employment are concentrated among
the most qualified professional groups (managers and clerks). A specular pattern is found
in the case of the low-tech industries where job losses are associated to the offshoring of
the least innovative stages of production and manual workers are those most penalised
BIOMONITORAGGIO PER LA PRESENZA DI DISTRUTTORI ENDOCRINI NEL FIUME CHIENTI: DUE METODOLOGIE A CONFRONTO
No full textLe acque superficiali ricevono un continuo apporto di sostanze inquinanti mediante gli scarichi urbani, industriali e le acque di dilavamento dei suoli agricoli., Molti di questi inquinanti possono funzionare da distruttori endocrini e, come ormai è ben noto, tali composti rappresentano una classe di contaminanti a diffusione ubiquitaria. Nel presente lavoro è stata valutata la presenza di di distruttori endocrini ad azione estrogenica (xenoestrogeni) nel fiume Chienti (Macerata) utilizzando un approccio integrato basato sull’impiego di test in vivo ed in vitro. Sono stati analizzati tre differenti siti: uno prossimo alla sorgente, uno nel tratto intermedio ed uno prossimo alla foce. Per quanto riguarda gli studi in vivo è stata valutata la comparsa della vitellogenina in giovanili di Carassius auratus mantenuti, per un periodo di tre settimane, in acqua prelevata nei diversi siti monitorati. Per gli studi in vitro, invece, è stata utilizzata una coltura cellulare di carcinoma di mammella estrogeno-dipendente (MCF-7) trattata con la frazione organica (estratta mediate cromatografia con colonnine C-18) dei campioni di acqua prelevati nei tre siti.
I risultati ottenuti indicano chiaramente come tutti i campioni di acqua testati siano in grado di indurre la sintesi di VTG in C. auratus e stimolare la proliferazione nella linea cellulare MCF-7; si dimostra inoltre come la concentrazione degli xenoestrogeni aumenta passando dal tratto montano alla foce.
La presenza di xenoestrogeni nel tratto prossimo alla sorgente va valutata tenendo conto del fatto che una piccola parte del bacino idrografico del fiume Chienti si trova negli altopiani di Colfiorito (Perugia) nei quali sono presenti coltivazioni intensive.
Appare significativo il fatto che i due metodi di studio applicati mostrano un risultato comparabile; questo dato fornisce supporto all'utilizzo di sistemi in vitro come primo livello di indagine per il monitoraggio degli xenoestrogeni limitando il più possibile il sacrificio di animali.
Progetto finanziato dalla Provincia di Macerata con delibera n.277 del 04/06/2009 della Giunta Provinciale di Macerata
La maturità di Alessandro Fei del Barbiere, in bilico tra Maniera e Riforma
No full textThis article studies the mature career of the Florentine painter Alessandro Fei del Barbiere (1537-1592), beginning with the rediscovery of the 'Ascension' altarpiece formerly in the Albizi Chapel in the destroyed church of San Pier Maggiore, Florence. Studying this painting and others recorded in 1584 by the biographer Raffaello Borghini, such as the two altarpieces for Santa Maria delle Grazie and the Madonna dell'Umiltà in Pistoia, the author reconstructs a body of works showing how in the 1580s Fei gradually went beyond the archaic style of his apprenticeship - he had been trained by Ridolfo del Ghirlandaio and Pierfrancesco Foschi, but was also marked by the Maniera of Vasari - evolving towards naturalism in both mimesis and pictorial handling. In Florence, his development partly parallels that of Santi di Tito and his circle, but Fei was also influenced by a probable sojourn during the early part of that decade in Rome, where he could have been inspired by Girolamo Muziano and the painters working for Pope Gregory XIII. Among other proposals, the author suggests that the artist was responsible for decorating the chancel of Fiesole Cathedral (c. 1584-1589), which consisted of an altarpiece, only rarely discussed by scholars, and a cycle of frescoes hitherto attributed to Nicodemo Ferrucci
Tra socialdemocrazie e Perestrojka. Le relazioni internazionali del Pci attraverso le carte di Alessandro Natta
No full textThis essay reconstructs the foreign policy of the Italian Communist Party during the four
years of Alessandro Natta’s secretariat (1984-1988) through largely original archival documentation,
from the Alessandro Natta Fonds of the Historical Archive of the Chamber of
Deputies. Natta’s papers are also cross-referenced with those kept in the PCI Archive at the
Gramsci Foundation. The author analyses the relationship that the PCI establishes with
Gorbachev’s Perestroika, Deng’s China, and European social democracies during the last
years of the Cold War
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