3,303 research outputs found
Espiritualidade política: a partir de Foucault e de Spinoza
No full textTese (doutorado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas. Programa de Pós-Graduação em FilosofiaO propósito desta tese é a constituição de uma ideia de "espiritua-lidade política". Esta expressão foi utilizada por Michel Foucault em apenas duas ocasiões: no contexto de uma série de reportagens sobre o acontecimento da Insurreição Iraniana de 1978-1979; e, posteriormente, de maneira sumária, para definir um tipo de relação entre vontade, verdade e governo de si e dos outros. Devido a este escasso uso, foi preciso explorar diferentes pistas. O resultado desta exploração perfaz a primeira parte de nosso estudo, em que a nossa expressão titular é referida a outras noções em Foucault, como a "atitude crítica" e o "nexus verdade-poder-sujeito". Como pontos de apoio, são explorados o momento insurrecional iraniano e o pensamento político de Khomeini e de Shari'ati. A radicalização dos termos envolvidos na definição foucaultiana de "espiritualidade política" nos deixa às portas de uma ontologia, que, para Foucault, entretanto, só se analisa como ficção. Munidos com a ideia de ficção, então, abordamos, na segunda parte deste estudo, alguns elementos da filosofia de Spinoza. A ontologia de Spinoza pertence a seu projeto ético-político de constituição erótica do verdadeiro, pelo conhecimento da união da mente com a natureza toda. União que se dá, como numa dobra pela qual e na qual se conectam a causalidade externa e a interna, na relação indissociável entre o nexus de causas e o conatus, segundo os três aspectos do real - o atributo, o modo infinito imediato e o mediado - que correspondem, no modo finito singular, à sua intensão, à sua forma e à sua extensão. A teoria do indivíduo, aplicada aos corpos políticos, apresenta as formas dos impérios como singularidades. Se, por um lado, as partes componentes do corpo político estabelecem umas com as outras relações sempre também passionais, por outro, são as ações livres de todas as suas partes juntas que explicam o processo de individuação de uma nova forma de império. É esse processo de individuação de uma potência não capturada e livre que nos permite conceber a ideia de "espiritualidade política" a partir de Spinoza.The purpose of this thesis is to construe an idea of "political spirituality." Michel Foucault used this expression in only two occasions: in the context of a series of reports based on the event of the Iranian Insurrection in 1978-1979; and, afterwards, as a brief way of defining a type of relationship between will, truth, and government of self and others. Due to this rare usage, it was necessary to explore different hints. The results of this exploration form the first part of this work, in which our title expression refers to other foucauldian notions such as "critical attitude" and "truth-power-subject nexus." The Iranian insurrectional moment and Khomeini's and Shari'ati's political thoughts are also explored. The investigation of the terms involved in the foucauldian definition of "political spirituality" leads us to an ontology, which for Foucault can only be analyzed as fiction. With the idea of fiction, then, in the second part of this work, we approach some elements of the philosophy of Spinoza. Spinoza's ontology pertains to his ethical-political project of an erotic constitution of the truthful, by means of knowledge of the union of mind and nature as a whole, given in the inseparable relation between the causal nexus and the conatus, as in and by a fold that connects the external and internal causality, according to the three aspects of reality - the attribute, the infinite immediate mode and the mediate - which correspond respectively, in the singular finite mode, to his intension, form and extension. The theory of the individual, applied to political bodies, presents the forms of empires as singularities. If, on one side, the components of a political body establish relations with each other that are also always passionate, on the other, there are free actions bestowed to all of his parts as a whole that explain the individuation process of a new form of empire. It is this individuation process of a non-captured free power (potentia) that allows us to conceive the idea of "political spirituality" out of Spinoza
Impact of multimodal MRI in the management of acute ischaemic stroke
No full textL'imagerie cérébrale joue un rôle crucial chez les patients victimes d'un accident vasculaire cérébral (AVC). L'avènement de la thrombectomie mécanique a bouleversé la prise en charge des patients atteints d'AVC ischémique et par conséquent la place de l'IRM à la phase aigüe. Notre travail de thèse se propose d'étudier l'apport de l'IRM multimodale dans la prise en charge de l'AVC ischémique à la phase aigüe. Dans cette perspective, nous avons couplé l'analyse des IRM d'admission de la cohorte HIBISCUS-STROKE (CoHort of Patients to Identify Biological and Imaging markerS of CardiovascUlar Outcomes in Stroke) au devenir fonctionnel, au volume final de l'infarctus et à la dynamique des marqueurs sériques de l'inflammation. Dans la première partie de notre travail, nous avons examiné l'apport de l'IRM dans la sélection des patients éligibles à une thrombectomie mécanique. Nous avons observé que les techniques d'angio-IRM étaient inférieures à l'artériographie cérébrale dans la localisation de l'occlusion intracrânienne malgré la prise en compte du caractère migratoire du thrombus. Nous avons montré que l'estimation du volume de la pénombre ischémique variait substantiellement selon le logiciel de post-traitement utilisé et que ces différences pouvaient impacter la sélection des patients éligibles à une thrombectomie mécanique. Dans une étude pilote, nous avons observé que les paramètres optimaux définissant le trouble de perfusion variaient selon le logiciel utilisé. Dans la deuxième partie de notre travail, nous avons évalué l'apport pronostic de l'IRM chez les patients ayant bénéficié d'une recanalisation efficace après thrombectomie mécanique. Nous avons observé que le « brush sign » était associé à une croissance >11.6mL du volume de l'infarctus et que des hypersignaux FLAIR vasculaires peu étendus étaient associés à un moins bon résultat fonctionnel à 3 mois. Dans la troisième partie de notre travail, nous avons examiné les relations entre la perméabilité de la barrière hémato-encéphalique sur l'IRM d'admission et la réponse neuroinflammatoire. Sur la population totale, nous avons montré qu'une perméabilité accrue de la barrière hémato-encéphalique était associée à un volume plus important de l'infarctus sur la population totale. Chez les patients à moins de 6h du début des symptômes, nous avons observé qu'une perméabilité accrue était associée à un volume plus important de l'infarctus et à des taux sériques plus importants de métalloprotéase matricielle 9. La cohorte HIBISCUS-STROKE nous a donc permis de préciser l'apport de l'IRM dans la sélection et le pronostic des patients et d'identifier les facteurs associés à une augmentation de la perméabilité de la barrière hémato-encéphalique à la phase aigüe.Cerebral imaging plays a crucial role in stroke patients. The advent of mechanical thrombectomy has transformed the management of acute ischemic stroke (AIS) patients, and consequently the role of MRI in the acute phase. Here, we propose to study the contribution of multimodal MRI to the management of AIS. To this end, we have coupled the analysis of admission MRI from the HIBISCUS-STROKE (CoHort of Patients to Identify Biological and Imaging markerS of CardiovascUlar Outcomes in Stroke) cohort with functional outcome, final infarct volume and the dynamics of serum markers of inflammation. In the first part of our work, we examined the contribution of MRI to the selection of patients eligible for mechanical thrombectomy. We observed that MRI angiography techniques were inferior to cerebral arteriography in localizing intracranial occlusion, despite taking into account the migratory nature of the thrombus. We showed that the estimation of the volume of the ischemic penumbra varied substantially according to the post-processing software used, and that these differences could have an impact on the selection of patients eligible for mechanical thrombectomy. In a pilot study, we observed that the optimal parameters defining the volumes of perfusion defect varied according to the software used. In the second part of our work, we assessed the prognostic contribution of MRI in patients who had achieved successful recanalization after mechanical thrombectomy. We observed that “brush sign” was associated with >11.6mL growth in infarct volume, and that mild vascular FLAIR hypersignals were associated with poorer functional outcome at 3 months. In the third part of our work, we examined the relationships between blood-brain barrier permeability on admission MRI and neuroinflammatory response. In the total population, we showed that increased blood-brain barrier permeability was associated with greater infarct volume. In patients within 6 hours of the onset of symptoms, we observed that increased permeability was associated with larger infarct volume and higher serum levels of matrix metalloprotease 9. The HIBISCUS-STROKE cohort gave us the opportunity to assess the contribution of MRI to patient selection and prognosis, and to identify factors associated with increased blood-brain barrier permeability in the acute phase
Impact de l'IRM multimodale dans la prise en charge des AVC ischémiques à la phase aigüe
No full textCerebral imaging plays a crucial role in stroke patients. The advent of mechanical thrombectomy has transformed the management of acute ischemic stroke (AIS) patients, and consequently the role of MRI in the acute phase. Here, we propose to study the contribution of multimodal MRI to the management of AIS. To this end, we have coupled the analysis of admission MRI from the HIBISCUS-STROKE (CoHort of Patients to Identify Biological and Imaging markerS of CardiovascUlar Outcomes in Stroke) cohort with functional outcome, final infarct volume and the dynamics of serum markers of inflammation. In the first part of our work, we examined the contribution of MRI to the selection of patients eligible for mechanical thrombectomy. We observed that MRI angiography techniques were inferior to cerebral arteriography in localizing intracranial occlusion, despite taking into account the migratory nature of the thrombus. We showed that the estimation of the volume of the ischemic penumbra varied substantially according to the post-processing software used, and that these differences could have an impact on the selection of patients eligible for mechanical thrombectomy. In a pilot study, we observed that the optimal parameters defining the volumes of perfusion defect varied according to the software used. In the second part of our work, we assessed the prognostic contribution of MRI in patients who had achieved successful recanalization after mechanical thrombectomy. We observed that “brush sign” was associated with >11.6mL growth in infarct volume, and that mild vascular FLAIR hypersignals were associated with poorer functional outcome at 3 months. In the third part of our work, we examined the relationships between blood-brain barrier permeability on admission MRI and neuroinflammatory response. In the total population, we showed that increased blood-brain barrier permeability was associated with greater infarct volume. In patients within 6 hours of the onset of symptoms, we observed that increased permeability was associated with larger infarct volume and higher serum levels of matrix metalloprotease 9. The HIBISCUS-STROKE cohort gave us the opportunity to assess the contribution of MRI to patient selection and prognosis, and to identify factors associated with increased blood-brain barrier permeability in the acute phase.L'imagerie cérébrale joue un rôle crucial chez les patients victimes d'un accident vasculaire cérébral (AVC). L'avènement de la thrombectomie mécanique a bouleversé la prise en charge des patients atteints d'AVC ischémique et par conséquent la place de l'IRM à la phase aigüe. Notre travail de thèse se propose d'étudier l'apport de l'IRM multimodale dans la prise en charge de l'AVC ischémique à la phase aigüe. Dans cette perspective, nous avons couplé l'analyse des IRM d'admission de la cohorte HIBISCUS-STROKE (CoHort of Patients to Identify Biological and Imaging markerS of CardiovascUlar Outcomes in Stroke) au devenir fonctionnel, au volume final de l'infarctus et à la dynamique des marqueurs sériques de l'inflammation. Dans la première partie de notre travail, nous avons examiné l'apport de l'IRM dans la sélection des patients éligibles à une thrombectomie mécanique. Nous avons observé que les techniques d'angio-IRM étaient inférieures à l'artériographie cérébrale dans la localisation de l'occlusion intracrânienne malgré la prise en compte du caractère migratoire du thrombus. Nous avons montré que l'estimation du volume de la pénombre ischémique variait substantiellement selon le logiciel de post-traitement utilisé et que ces différences pouvaient impacter la sélection des patients éligibles à une thrombectomie mécanique. Dans une étude pilote, nous avons observé que les paramètres optimaux définissant le trouble de perfusion variaient selon le logiciel utilisé. Dans la deuxième partie de notre travail, nous avons évalué l'apport pronostic de l'IRM chez les patients ayant bénéficié d'une recanalisation efficace après thrombectomie mécanique. Nous avons observé que le « brush sign » était associé à une croissance >11.6mL du volume de l'infarctus et que des hypersignaux FLAIR vasculaires peu étendus étaient associés à un moins bon résultat fonctionnel à 3 mois. Dans la troisième partie de notre travail, nous avons examiné les relations entre la perméabilité de la barrière hémato-encéphalique sur l'IRM d'admission et la réponse neuroinflammatoire. Sur la population totale, nous avons montré qu'une perméabilité accrue de la barrière hémato-encéphalique était associée à un volume plus important de l'infarctus sur la population totale. Chez les patients à moins de 6h du début des symptômes, nous avons observé qu'une perméabilité accrue était associée à un volume plus important de l'infarctus et à des taux sériques plus importants de métalloprotéase matricielle 9. La cohorte HIBISCUS-STROKE nous a donc permis de préciser l'apport de l'IRM dans la sélection et le pronostic des patients et d'identifier les facteurs associés à une augmentation de la perméabilité de la barrière hémato-encéphalique à la phase aigüe
Impact de l'IRM multimodale dans la prise en charge des AVC ischémiques à la phase aigüe
No full textCerebral imaging plays a crucial role in stroke patients. The advent of mechanical thrombectomy has transformed the management of acute ischemic stroke (AIS) patients, and consequently the role of MRI in the acute phase. Here, we propose to study the contribution of multimodal MRI to the management of AIS. To this end, we have coupled the analysis of admission MRI from the HIBISCUS-STROKE (CoHort of Patients to Identify Biological and Imaging markerS of CardiovascUlar Outcomes in Stroke) cohort with functional outcome, final infarct volume and the dynamics of serum markers of inflammation. In the first part of our work, we examined the contribution of MRI to the selection of patients eligible for mechanical thrombectomy. We observed that MRI angiography techniques were inferior to cerebral arteriography in localizing intracranial occlusion, despite taking into account the migratory nature of the thrombus. We showed that the estimation of the volume of the ischemic penumbra varied substantially according to the post-processing software used, and that these differences could have an impact on the selection of patients eligible for mechanical thrombectomy. In a pilot study, we observed that the optimal parameters defining the volumes of perfusion defect varied according to the software used. In the second part of our work, we assessed the prognostic contribution of MRI in patients who had achieved successful recanalization after mechanical thrombectomy. We observed that “brush sign” was associated with >11.6mL growth in infarct volume, and that mild vascular FLAIR hypersignals were associated with poorer functional outcome at 3 months. In the third part of our work, we examined the relationships between blood-brain barrier permeability on admission MRI and neuroinflammatory response. In the total population, we showed that increased blood-brain barrier permeability was associated with greater infarct volume. In patients within 6 hours of the onset of symptoms, we observed that increased permeability was associated with larger infarct volume and higher serum levels of matrix metalloprotease 9. The HIBISCUS-STROKE cohort gave us the opportunity to assess the contribution of MRI to patient selection and prognosis, and to identify factors associated with increased blood-brain barrier permeability in the acute phase.L'imagerie cérébrale joue un rôle crucial chez les patients victimes d'un accident vasculaire cérébral (AVC). L'avènement de la thrombectomie mécanique a bouleversé la prise en charge des patients atteints d'AVC ischémique et par conséquent la place de l'IRM à la phase aigüe. Notre travail de thèse se propose d'étudier l'apport de l'IRM multimodale dans la prise en charge de l'AVC ischémique à la phase aigüe. Dans cette perspective, nous avons couplé l'analyse des IRM d'admission de la cohorte HIBISCUS-STROKE (CoHort of Patients to Identify Biological and Imaging markerS of CardiovascUlar Outcomes in Stroke) au devenir fonctionnel, au volume final de l'infarctus et à la dynamique des marqueurs sériques de l'inflammation. Dans la première partie de notre travail, nous avons examiné l'apport de l'IRM dans la sélection des patients éligibles à une thrombectomie mécanique. Nous avons observé que les techniques d'angio-IRM étaient inférieures à l'artériographie cérébrale dans la localisation de l'occlusion intracrânienne malgré la prise en compte du caractère migratoire du thrombus. Nous avons montré que l'estimation du volume de la pénombre ischémique variait substantiellement selon le logiciel de post-traitement utilisé et que ces différences pouvaient impacter la sélection des patients éligibles à une thrombectomie mécanique. Dans une étude pilote, nous avons observé que les paramètres optimaux définissant le trouble de perfusion variaient selon le logiciel utilisé. Dans la deuxième partie de notre travail, nous avons évalué l'apport pronostic de l'IRM chez les patients ayant bénéficié d'une recanalisation efficace après thrombectomie mécanique. Nous avons observé que le « brush sign » était associé à une croissance >11.6mL du volume de l'infarctus et que des hypersignaux FLAIR vasculaires peu étendus étaient associés à un moins bon résultat fonctionnel à 3 mois. Dans la troisième partie de notre travail, nous avons examiné les relations entre la perméabilité de la barrière hémato-encéphalique sur l'IRM d'admission et la réponse neuroinflammatoire. Sur la population totale, nous avons montré qu'une perméabilité accrue de la barrière hémato-encéphalique était associée à un volume plus important de l'infarctus sur la population totale. Chez les patients à moins de 6h du début des symptômes, nous avons observé qu'une perméabilité accrue était associée à un volume plus important de l'infarctus et à des taux sériques plus importants de métalloprotéase matricielle 9. La cohorte HIBISCUS-STROKE nous a donc permis de préciser l'apport de l'IRM dans la sélection et le pronostic des patients et d'identifier les facteurs associés à une augmentation de la perméabilité de la barrière hémato-encéphalique à la phase aigüe
Impact de l'IRM multimodale dans la prise en charge des AVC ischémiques à la phase aigüe
No full textCerebral imaging plays a crucial role in stroke patients. The advent of mechanical thrombectomy has transformed the management of acute ischemic stroke (AIS) patients, and consequently the role of MRI in the acute phase. Here, we propose to study the contribution of multimodal MRI to the management of AIS. To this end, we have coupled the analysis of admission MRI from the HIBISCUS-STROKE (CoHort of Patients to Identify Biological and Imaging markerS of CardiovascUlar Outcomes in Stroke) cohort with functional outcome, final infarct volume and the dynamics of serum markers of inflammation. In the first part of our work, we examined the contribution of MRI to the selection of patients eligible for mechanical thrombectomy. We observed that MRI angiography techniques were inferior to cerebral arteriography in localizing intracranial occlusion, despite taking into account the migratory nature of the thrombus. We showed that the estimation of the volume of the ischemic penumbra varied substantially according to the post-processing software used, and that these differences could have an impact on the selection of patients eligible for mechanical thrombectomy. In a pilot study, we observed that the optimal parameters defining the volumes of perfusion defect varied according to the software used. In the second part of our work, we assessed the prognostic contribution of MRI in patients who had achieved successful recanalization after mechanical thrombectomy. We observed that “brush sign” was associated with >11.6mL growth in infarct volume, and that mild vascular FLAIR hypersignals were associated with poorer functional outcome at 3 months. In the third part of our work, we examined the relationships between blood-brain barrier permeability on admission MRI and neuroinflammatory response. In the total population, we showed that increased blood-brain barrier permeability was associated with greater infarct volume. In patients within 6 hours of the onset of symptoms, we observed that increased permeability was associated with larger infarct volume and higher serum levels of matrix metalloprotease 9. The HIBISCUS-STROKE cohort gave us the opportunity to assess the contribution of MRI to patient selection and prognosis, and to identify factors associated with increased blood-brain barrier permeability in the acute phase.L'imagerie cérébrale joue un rôle crucial chez les patients victimes d'un accident vasculaire cérébral (AVC). L'avènement de la thrombectomie mécanique a bouleversé la prise en charge des patients atteints d'AVC ischémique et par conséquent la place de l'IRM à la phase aigüe. Notre travail de thèse se propose d'étudier l'apport de l'IRM multimodale dans la prise en charge de l'AVC ischémique à la phase aigüe. Dans cette perspective, nous avons couplé l'analyse des IRM d'admission de la cohorte HIBISCUS-STROKE (CoHort of Patients to Identify Biological and Imaging markerS of CardiovascUlar Outcomes in Stroke) au devenir fonctionnel, au volume final de l'infarctus et à la dynamique des marqueurs sériques de l'inflammation. Dans la première partie de notre travail, nous avons examiné l'apport de l'IRM dans la sélection des patients éligibles à une thrombectomie mécanique. Nous avons observé que les techniques d'angio-IRM étaient inférieures à l'artériographie cérébrale dans la localisation de l'occlusion intracrânienne malgré la prise en compte du caractère migratoire du thrombus. Nous avons montré que l'estimation du volume de la pénombre ischémique variait substantiellement selon le logiciel de post-traitement utilisé et que ces différences pouvaient impacter la sélection des patients éligibles à une thrombectomie mécanique. Dans une étude pilote, nous avons observé que les paramètres optimaux définissant le trouble de perfusion variaient selon le logiciel utilisé. Dans la deuxième partie de notre travail, nous avons évalué l'apport pronostic de l'IRM chez les patients ayant bénéficié d'une recanalisation efficace après thrombectomie mécanique. Nous avons observé que le « brush sign » était associé à une croissance >11.6mL du volume de l'infarctus et que des hypersignaux FLAIR vasculaires peu étendus étaient associés à un moins bon résultat fonctionnel à 3 mois. Dans la troisième partie de notre travail, nous avons examiné les relations entre la perméabilité de la barrière hémato-encéphalique sur l'IRM d'admission et la réponse neuroinflammatoire. Sur la population totale, nous avons montré qu'une perméabilité accrue de la barrière hémato-encéphalique était associée à un volume plus important de l'infarctus sur la population totale. Chez les patients à moins de 6h du début des symptômes, nous avons observé qu'une perméabilité accrue était associée à un volume plus important de l'infarctus et à des taux sériques plus importants de métalloprotéase matricielle 9. La cohorte HIBISCUS-STROKE nous a donc permis de préciser l'apport de l'IRM dans la sélection et le pronostic des patients et d'identifier les facteurs associés à une augmentation de la perméabilité de la barrière hémato-encéphalique à la phase aigüe
CT-based radiomics analysis of peri intracerebral hemorrhage edema: A new tool to predict functional outcome
No full textInternational audienceIn patients with intracerebral hemorrhage (ICH), direct lacerations of brain tissue cause immediate and delayed neurological damage that may result in death and long-term disability. To date, therapeutic approaches focus primarily on preventing ICH expansion by controlling blood pressure, reversing any associated coagulopathy, and providing care in dedicated stroke unit [1]. During previous years, hemostatic agents in the absence of known coagulopathy have attracted interest but randomized clinical trials failed to demonstrate their benefit [1]. Most recently, the Early Minimally Invasive Removal of Intracerebral Hemorrhage (ENRICH) clinical trial has raised hopes by demonstrating, for the first time, a functional benefit of minimally invasive surgical drainage in supra-tentorial ICH [2]. Another strategy under development is to target secondary injury pathways. In the days and weeks following the initial injury, the cytotoxic release and neuroinflammatory response associated with ICH cause further damage to surrounding tissue, which may be inhibited by drugs [3]. The evaluation of these novel therapies will require biomarkers to select patients most at risk of secondary brain injury. Because the diagnosis of ICH relies primarily on computed tomography (CT) examination, CT-based biomarkers would be ideal for this purpose. As a site receiving red cell debris and inflammatory mediators, peri‑ICH edema seems to be the most promising location to find such biomarkers [3].In this issue of Diagnostic and Interventional Imaging, Huang et al. performed a CT-based radiomics analysis thoughtfully focusing on peri‑ICH edema [4]. They built and validated a radiomics based-CT model predictive of functional outcome at 90-day using admission noncontrast CT examination. Their radiomics analysis (i.e., the quantification of images texture and shape characteristics) indicates a greater heterogeneity of peri‑ICH edema in patients with worst functional outcome, thereby suggesting a relationship with the occurrence of secondary brain injury in these patients. Translational studies on animal models could strengthen the interpretability of the radiomics parameters highlighted in this study by associating them specifically with the various histopathological lesions observed in the peri‑ICH zone [5].However, as acknowledged by the authors, the clinical value added by this complex and time-consuming approach remains modest at present, when compared to a conventional model that considers easily accessible parameters such as patient age, severity of consciousness impairment according to the Glasgow Coma Scale, blood glucose, and ICH volume and location. Prospects for improvement undoubtedly include optimizing the timing of data acquisition. The development of peri‑ICH edema is a highly dynamic process that spans several weeks, reaching its peak volume around the third week [3]. Throughout this period, a cascade of events occurs, involving excitotoxicity, blood-brain barrier disruption, and neuroinflammation. While the primary goal of this cascade is ICH resorption, its dysregulation could have adverse consequences for some patients. In this context, assessing the pathological mechanisms at play in the peri‑ICH zone within the first six hours of ICH formation may be too early to capture the dynamics accurately.Ultimately, for the future use of such a tool in clinical practice, two key requirements need to be addressed. They include validation of its robustness against local technical variations, including machine effects and segmentation methods, and smooth integration into the radiologist's workflow, encompassing the full automation of the entire procedure (including peri‑ICH edema segmentation) [6]. Only under these conditions will radiomics offer a new perspective on peri‑ICH edema and guide the utilization of innovative therapies
La filosofía del derecho de Alexandre Kojève
No full textThis article is a presentation of Alexandre Kojève’s philosophy of law, exposed in his Esquisse d’une phénoménologie du droit (1981). Little attention has been paid to this work. So there is a gap that has to be filled with a critical reflection of its strengths. Among them, undoubtedly, we count the fact that Kojève is introducing a conception of international justice that casts a singular light on current debates about cosmopolitanism and globalization. According to this author, citizenship is the key element of the process of global expansion of the juridical sphere. In sum, Kojève’s philosophy is useful to reflect upon the contrast between the juridical and the political, which is the basis for all philosophy of law, in order to achieve world peace and international justice.Este artículo es una presentación de la filosofía del derecho de Alexandre Kojève contenida en su Esquisse d’une phénoménologie du droit (1981). La poca atención que dicha obra ha recibido es un vacío que debiera llenarse con una reflexión crítica de sus puntos fuertes. Entre ellos destaca una concepción de la justicia internacional que proyecta una luz muy singular sobre los actuales debates en torno a la globalización y el cosmopolitismo. A ojos de este autor, la ciudadanía es el elemento clave para aquilatar la expansión global de lo jurídico. En suma, Kojève aparece como un valioso referente en la labor de pensar la contraposición entre lo jurídico y lo político que está en la base de toda filosofía del derecho, con la aspiración al logro de la justicia internacional y la paz mundial en el horizonte
Reconfiguração do consensualismo contratual: as ações tituladas nominativas e os limites à transmissão
No full textPartimos da evolução histórica do consensualismo contratual salientando os
principais carateres que, nos diversos momentos históricos, se foram evidenciando.
Numa segunda etapa exploramos os fundamentos dogmáticos do modelo de
transmissão contratual assumido pelo legislador e a sua viabilidade no sistema
jurídico global, em particular, no direito dos valores mobiliários. Constatamos a
crescente necessidade na prática mercantil e inevitabilidade no sistema jurídico
global da admissibilidade da existência de contratos de compra e venda de natureza
meramente obrigacional. Num terceiro momento desenvolvemos os principais
aspetos do regime jurídico aplicável às ações tituladas nominativas fora do mercado
regulado, em particular, os principais limites à transmissão, enquanto instrumentos/barreiras ao consensualismo contratual.We start from the historical evolution of contractual consensualism emphasizing the
main aspects that, in different historical moments, were showing up. In a second
stage we explore the dogmatic foundations of the transmission model contractual
assumed by the legislator and its viability in the global legal system, in particular, in
securities law. We note the growing need in commercial practice and inevitability in
the global legal system the admissibility of the existence of contracts of sale purely
obligatory. In the third stage we develop the main aspects of the legal regime
applicable to nominative titled actions outside the regulated market, in particular,
the main limits to the transmission, as instruments / barriers to contractual
consensualism
“Era por Alexandre tod’esto demostrado”: ¿pruebas verídicas y pruebas engañosas en el Libro de Alexandre?
No full textEl Libro de Alexandre es un texto de s. XIII, que se escribió en la España medieval. En este escrito, el autor pretende demostrar que, en el Alexandre, algunas de las situaciones que se ponen a prueba son aceptadas, pero eso no significa que el macedonio gane la prueba. El articulo esta dividido en tres apartados. En el primero, el autor da cuenta de la historia textual de la obra y también dedica ciertas líneas al Estado de la cuestión del texto; mientras que, en la segunda parte, nos guía a conceptos etimológicos de los términos prueba, evidencia y demás. En el tercer apartado se centra en algunas pruebas expuestas en el Libro de Alexandre.The Libro de Alexandre is a literary work, written during the medieval Spain. In this paper, the author tries to demonstrate that, carefully reading the L.A, some of the situations that are set as proves are accepted, but it does not mean that Alexander can be a victor. This paper is divided in three sections: firstly, the author tells the textual history of the L.A and, then, tries to update the State of art: on the other hand, in the second part, the author offers meanings about terms as: prueba and evidencia. Finally, the author focuses on certain passages contained in the Libro de Alexandre that can be taken as failed proves
Mixing the Immiscible: Improvisation within Fixed-Media Composition
No full textThis paper will explore ways in which mastered improvisation practice, with the studio as an instrument, is a proposed avenue to bridge the historical dichotomy between what Ted Gioia describe as ‘the aesthetics of perfection’ and ‘the aesthetics of imperfection’. It is proposed as a way to re-embody fixed music, as experimented by the author through the composition of his last fixed-media work. This will be put in the context of a wider trend observed amongst the current emerging generation of composers interested in the aesthesics of the work, by opposition to the previous generations that placed the value of the work in its poietics. The vital and primal importance of practice outcome as practice-based research’s main document will also be advocated for, as these trends are happening in the laboratory of live music
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