50 research outputs found
Analisis Kestabilan Lereng Pit B Tambang PT. Miyor Pratama Coal, Desa Kumanis Atas Kec. Talawi, Sawahlunto Sumatera Barat
No full textThe purpose of this research is a classification of rock from slopes and analyzes safety factor of slope by fellenius and janbu method. This type of research classified as descriptive. For class of rock mass based on bieniawski 1989 and for processing helped with software slide v. 6.0. Research results explain the total weights of Rock Mass Rating (RMR) from the results of the data from field, the total weights is = 46 so the rocks are at class III (moderate), with cohesion value 250 kPa and the friction angle is 30 o. The value of the slope safety factor pit B PT. Miyor Pratama Coal after using the slide programme V. 6.0 with method of Bishop has Safety factor = 2,093, and with Janbu method has safety factor = 2,180. From two methods include safe condition > 1
ALTERNATIF PERHITUNGAN RETURN SHAHIBUL MAL PADA SKEMA MUDHARABAH BANK SYARIAH
No full textAbstract:
The rapid development of the number of islamic banks should be balanced with the availability of infrastructure to carry out daily operational practices. The operational tools include hardware as like as representative office, computerized system, reliable human resources and software as like as method, culture and financial and islamic banking knowledge. In terms of development of Islamic finance is the paper "Alternative Calculation of Return Shahibul Mal on Mudharabah Scheme on Bank Syariah" was written. During this calculation of return shahibul mal has not been standardized in a formula, thus causing two serious effects. First, in the theoretical level, the formula has not yet created a difficulty. Secondly, in practical level, the formula is not impressive enough to recalculate the complexity of return calculations obtained by shahibul mall, causing laziness of the community using the services of islamic bank. This paper using mathematical and arithmetic equations with the help of modeling made by the author to refine and improve the method of calculation that has been available. The purpose of this paper is to create a standard formula that facilitates the calculation of return earned by a shahibul mal in a mudaraba scheme in a islamic bank.
 
Analisis Penerapan Akuntansi Aset Tetap Pada Pt. Deco Internusa Cemerlang Pekanbaru
No full textPT. Deco Internusa Cemerlang Pekanbaru is a company operating in the electrical services sector. This company has fixed assets consisting of buildings, vehicles, business equipment and office equipment. The purpose of this research is to determine the suitability of implementing fixed asset accounting at PT. Deco Internusa Cemerlang Pekanbaru with Generally Accepted Accounting Principles. This research was carried out at PT. Deco Internusa Cemerlang Pekanbaru. The author uses qualitative methods. The types of data that will be collected in this research include Primary Data and Secondary Data. Data collection techniques in this research are interviews and documentation. After all the data was collected, the data was analyzed using descriptive methods. Based on the research results, it was found that the cost of acquiring fixed assets is recognized and assessed based on the acquisition cost plus costs incurred from the purchasing process up to the availability for use of the fixed assets. Accounting treatment of depreciation of fixed assets at PT. Deco Internusa Cemerlang does not pay attention to the acquisition date of fixed assets, thereby affecting the depreciation and accumulated depreciation of fixed assets. The company has not differentiated between capital expenditure and revenue expenditure. The company does not write off or dispose of fixed assets that are no longer used in accordance with financial accounting standards. Overall it can be concluded that the application of fixed asset accounting at PT. Deco Internusa Cemerlang is not in accordance with Generally Accepted Accounting Principles
Peradilan Agama Era Reformasi Kedua Setelah Berlakunya Undang-Undang Nomor 3 Tahun 2006 Tentang Peradilan Agama
No full textThis paper is intended to examine the proliferation of economic dispute resolution
Shari'ah after amendment to the Constitution 1945. Before the change, the Religious
Courts (PA) as the top judicary are authorized to settle disputes Shariah economy.
Now, the judiciary as an institution of Shariah economic dispute resolution experience
proliferation, because the General Court entitled to handle economic disputes Shari'ah
under Article 55 paragraph (2) of Law No. 21 of 2008 concerning Islamic Banking.
Due to the proliferation of a completion of economic disputes Shari'ah raises choice of
forum which in the case of the same substance, the same object, then given the freedom to
choose, so that will give rise to legal disorder (chaos law). In addition, the decision would
lead to disparities, are also likely to occur strangeness, because maybe when sentence
born of religious courts, while the verdict b born of a general court for the same case, or
there are two cases that have similar or even the same same, there will be oddity for the
party receiving
Lymphadenectomy and pelvic irradiation in high-risk endometrioid endometrial cancer: A population-based retrospective analysis using the SEER databank
No full textNeoadjuvant chemotherapy and the complexity of operative procedure in advanced epithelial ovarian cancer: a retrospective analysis
No full textIntroduction: Complete tumor resection for epithelial ovarian cancer (EOC) generally incorporates complex surgical maneuvers,
especially bowel resection. This study retrospectively analyzed the impact of neoadjuvant chemotherapy (NAC) on complexity of
surgical procedures for EOC (represented by bowel resection) and postoperative morbidity.
Methods: We retrospectively recruited all patients with Fédération Internationale de Gynécologie et d'Obstétrique (FIGO) stages
IIIC–IVB EOC who were treated in our center between 2011 and 2016. Patients were divided into those who received primary
debulking followed by chemotherapy (group A), and those who received NAC followed by interval debulking (group B). Patient age,
tumor stage, grade, dates of commencement and completion of therapy, intraoperative events, completion of surgical resection, and
postoperative events were evaluated.
Results: Of 92 patients, 42 were assigned to group A and 50 to group B. Their FIGO stages were group A—stages IIIC: 34 (80.9%),
IVA: 6 (14.3%), and IVB: 2 (4.8%); and group B—stages IIIC: 45 (90%), IVA: 5 (10%), and IVB: 0 (0%). The 2 groups did not
significantly differ in completeness of surgical cytoreduction or rates of bowel resection, intraoperative complications, or
postoperative morbidities.
Conclusion: NAC did not reduce rates of bowel resection, intraoperative complications, and postoperative morbidity in advanced
EOC compared with primary surgical cytoreduction. Future prospective studies will be required to corroborate our results
Prospective evaluation of weekly concomitant tumor bed boost with three-week hypofractionated whole breast irradiation in early breast cancer
No full textObjectives: A prospective study was conducted to assess the acute and late toxicity of hypofractionated whole breast irradiation with a weekly concomitant boost for women with early breast cancer (EBC). Methods: Women with EBC who underwent breast-conserving surgery were eligible. A dose of 40Gy in 15 fractions over 3 weeks was delivered to the whole breast with a concomitant weekly boost to the post-operative cavity of 3Gy in three fractions. Toxicity was graded using the Radiation Therapy Oncology Group (RTOG) acute toxicity and RTOG/EORTC late toxicity scales. Results: A total of 67 women were enrolled with a median age of 49 years (range 31–69). Median follow-up was 25 months (range 11–34). Acute skin reactions included grade (G) 1 (n = 47, 70%), G2 (n = 10, 13%), and G3 (n = 1, 1.5%). Late skin toxicity was observed in 13 patients (19%), all of whom experienced G1 toxicity only. On multivariable analysis, diabetes mellitus was predictive of acute skin toxicity (p = 0.003), while age less than 50 years (p = 0.029) and diabetes mellitus (p = 0.013) were predictive of late skin toxicity. Conclusions: Whole breast irradiation with concomitant weekly boost appears feasible and safe. Further investigation is required to fully evaluate this schedule as an alternative to conventional whole breast irradiation with a sequential boost
MiR-590-3p promotes ovarian cancer growth and metastasis via a novel FOXA2-versican pathway
No full textAbstract
miRNAs play important roles in gene regulation, and their dysregulation is associated with many diseases, including epithelial ovarian cancer (EOC). In this study, we determined the expression and function of miR-590-3p in EOC. miR-590-3p levels were higher in high-grade carcinoma when compared with low-grade or tumors with low malignant potential. Interestingly, plasma levels of miR-590-3p were significantly higher in patients with EOC than in subjects with benign gynecologic disorders. Transient transfection of miR-590-3p mimics or stable transfection of mir-590 increased cell proliferation, migration, and invasion. In vivo studies revealed that mir-590 accelerated tumor growth and metastasis. Using a cDNA microarray, we identified forkhead box A2 (FOXA2) and versican (VCAN) as top downregulated and upregulated genes by mir-590, respectively. miR-590-3p targeted FOXA2 3′ UTR to suppress its expression. In addition, knockdown or knockout of FOXA2 enhanced cell proliferation, migration, and invasion. Overexpression of FOXA2 decreased, whereas knockout of FOXA2 increased VCAN mRNA and protein levels, which was due to direct binding and regulation of the VCAN gene by FOXA2. Interrogation of the TCGA ovarian cancer database revealed a negative relationship between FOXA2 and VCAN mRNA levels in EOC tumors, and high FOXA2/low VCAN mRNA levels in tumors positively correlated with patient survival. Finally, overexpression of FOXA2 or silencing of VCAN reversed the effects of mir-590. These findings demonstrate that miR-590-3p promotes EOC development via a novel FOXA2–VCAN pathway.
Significance: Low FOXA2/high VCAN levels mediate the tumor-promoting effects of miR-590-3p and negatively correlate with ovarian cancer survival. Cancer Res; 78(15); 4175–90. ©2018 AACR.</jats:p
