1,721,052 research outputs found
Phenotypic Image Analysis Software Tools for Exploring and Understanding Big Image Data from Cell-Based Assays
No full textPhenotypic image analysis is the task of recognizing variations in cell properties using microscopic image data. These variations, produced through a complex web of interactions between genes and the environment, may hold the key to uncover important biological phenomena or to understand the response to a drug candidate. Today, phenotypic analysis is rarely performed completely by hand. The abundance of high-dimensional image data produced by modern high-throughput microscopes necessitates computational solutions. Over the past decade, a number of software tools have been developed to address this need. They use statistical learning methods to infer relationships between a cell's phenotype and data from the image. In this review, we examine the strengths and weaknesses of non-commercial phenotypic image analysis software, cover recent developments in the field, identify challenges, and give a perspective on future possibilities. The goal of phenotypic image analysis is to recognize variations in cellular properties using image data—either measurements extracted by image analysis software or directly from the raw pixel values. In this review, we describe free and open-source software tools that are currently available for exploring and quantifying phenotypes in image-based cellular assays. We discuss some of the main challenges, current trends, and future research directions in phenotypic image analysis
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
To Adapt or Not to Adapt? Real-Time Adaptation for Semantic Segmentation
No full textThe goal of Online Domain Adaptation for semantic segmentation is to handle unforeseeable domain changes that occur during deployment, like sudden weather events. However, the high computational costs associated with bruteforce adaptation make this paradigm unfeasible for realworld applications. In this paper we propose HAMLET, a Hardware-Aware Modular Least Expensive Training framework for real-time domain adaptation. Our approach includes a hardware-aware back-propagation orchestration agent (HAMT) and a dedicated domain-shift detector that enables active control over when and how the model is adapted (LT). Thanks to these advancements, our approach is capable of performing semantic segmentation while simultaneously adapting at more than 29FPS on a single consumer-grade GPU. Our framework's encouraging accuracy and speed trade-off is demonstrated on OnDA and SHIFT benchmarks through experimental results.</p
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Visual Representations and Models: From Latent SVM to Deep Learning
No full textTwo important components of a visual recognition system are representation and model. Both involves the selection and learning of the features that are indicative for recognition and discarding those features that are uninformative. This thesis, in its general form, proposes different techniques within the frameworks of two learning systems for representation and modeling. Namely, latent support vector machines (latent SVMs) and deep learning. First, we propose various approaches to group the positive samples into clusters of visually similar instances. Given a fixed representation, the sampled space of the positive distribution is usually structured. The proposed clustering techniques include a novel similarity measure based on exemplar learning, an approach for using additional annotation, and augmenting latent SVM to automatically find clusters whose members can be reliably distinguished from background class. In another effort, a strongly supervised DPM is suggested to study how these models can benefit from privileged information. The extra information comes in the form of semantic parts annotation (i.e. their presence and location). And they are used to constrain DPMs latent variables during or prior to the optimization of the latent SVM. Its effectiveness is demonstrated on the task of animal detection. Finally, we generalize the formulation of discriminative latent variable models, including DPMs, to incorporate new set of latent variables representing the structure or properties of negative samples. Thus, we term them as negative latent variables. We show this generalization affects state-of-the-art techniques and helps the visual recognition by explicitly searching for counter evidences of an object presence. Following the resurgence of deep networks, in the last works of this thesis we have focused on deep learning in order to produce a generic representation for visual recognition. A Convolutional Network (ConvNet) is trained on a largely annotated image classification dataset called ImageNet with million images. Then, the activations at each layer of the trained ConvNet can be treated as the representation of an input image. We show that such a representation is surprisingly effective for various recognition tasks, making it clearly superior to all the handcrafted features previously used in visual recognition (such as HOG in our first works on DPM). We further investigate the ways that one can improve this representation for a task in mind. We propose various factors involving before or after the training of the representation which can improve the efficacy of the ConvNet representation. These factors are analyzed on 16 datasets from various subfields of visual recognition.QC 20160908</p
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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