156 research outputs found
Annihilators of principal ideals in the exterior algebra
No full textKoç, Cemal (Dogus Author) -- Esin, Songül (Dogus Author)In this paper we describe annihilators of principal ideals of exterior algebras. For odd elements we establish formulae for dimensions of their principal ideals and their annihilators. For even elements we exhibit (multiplicative) generators for annihilator ideals
Comparative law at a crossroads
No full textA book which seeks to bring a fresh
approach to many of the issues in comparative law was launched in
December 2007 at the IALS. The author, a co-editor of Comparative
Law: A Handbook, explains what the new volume is seeking to
achieve. Article by Esin Örücü (Honorary Senior Research Fellow
and Professor Emeritus of Comparative Law, University of Glasgow
and Professor Emeritus of Comparative Law, Erasmus Universiteit
Rotterdam) published in Amicus Curiae - Journal of the Society
for Advanced Legal Studies. The Journal is produced by the
Society for Advanced Legal Studies at the Institute of Advanced
Legal Studies, University of London
Comparative law at a crossroads
No full textA book which seeks to bring a fresh approach to many of the issues in comparative law was launched in December 2007 at the IALS. The author, a co-editor of Comparative Law: A Handbook, explains what the new volume is seeking to achieve. Article by Esin Örücü (Honorary Senior Research Fellow and Professor Emeritus of Comparative Law, University of Glasgow and Professor Emeritus of Comparative Law, Erasmus Universiteit Rotterdam) published in Amicus Curiae - Journal of the Society for Advanced Legal Studies. The Journal is produced by the Society for Advanced Legal Studies at the Institute of Advanced Legal Studies, University of London
KATI ATIK YÖNETİMİ VE MODEL ÖNERİSİ: MAMAK BELEDİYESİ ÖRNEĞİ
No full textBu çalışmada Ankara’da katı atık yönetimi konusunda baş aktörlerden biri olan ITC (Invest Trading & Consulting AG) Firması ile ilçe belediyelerinden Mamak Belediyesinin atık yönetimi konusunda hangi politikaları izlemiş oldukları ve bu yönetimi gerçekleştirmek için hangi faaliyetleri yapmış oldukları incelenmiştir. ITC Firması; Mamak katı atık sahasının rehabilite edilmesi ve Ankara’da katı atık yönetiminin profesyonel bir şekilde yürütülmesi amacı ile Ankara katı atık yönetim projesinde yer alırken, Mamak Belediyesi atık oluşumunun önlenmesi için oluşturulan Sıfır Atık Projesinde görev almaktadır. ITC Firması bünyesinde bulundurduğu tesisler ile depolanacak atık miktarını en aza indirmeyi amaçlamaktadır. Mamak Belediyesi bünyesinde yapılan çalışmalar ise temizlik işleri müdürlüğü tarafından yürütülmekte olup, toplumun atık yönetimi konusunda yerel yönetimlerden beklentileri doğrultusunda hareket ederek atıkların toplanması ve taşınması görevini yerine getirmekte ve çevre temizliğini de yapmaktadır. Yüz yüze yapılan görüşmeler sonucunda elde edilen veriler ITC Firması bünyesindeki tesisin nasıl işlediği, katı atıkların hangi işlemlerden geçerek bertaraf edildiği verilerine ulaşılmıştır. Buna ilave olarak araştırmada Mamak Belediyesi bünyesindeki temizlik işleri müdürlüğünün faaliyetleri de kısaca ele alınmış ve temel sorunların tespiti yapılmıştır.
Belediyeleri atık yönetimini konusunda tam bir donanıma, ileri teknolojiye, iyi yetişmiş personele ve profesyonel bir yönetim anlayışının gerçekleşmesi adına yapılacak tesislere sahip oldurabilecek ekonomik kaynakların yeterli düzeyde olmadığı görülmektedir. Bu duruma çözüm üretmek için araştırmada üç adet model önerisi örneği sunulmuştur. Hemen her model önerisinde proje geliştirme, proje değerleme, proje finansmanı ile proje ve tesis yönetimi konularının özel önem taşıdığının vurgulanması gerekmektedir. Bu model önerilerinin dışında katı atık yönetimini gerçekleştirecek tesisleri yönetecek kişilerde en azından ilgili alanlarda lisansüstü eğitim yapmış olma ve belirli bir süre mesleğini icra etme şartı aranmalıdır. Bununla birlikte tesis yönetimi konusunda uzman olan kişilerin katı atık yönetim sürecinde görev almaları ve bu çerçevede üniversitelerin gayrimenkul geliştirme ve yönetimi bölümlerinin lisans ve lisansüstü programlarından mezun olan uzmanların istihdam edilmesine ağırlık verilmesi yararlı olacaktır
Analysis of nonlinear compartmental model using a reliable method
No full textThe goal of this work is to investigate nonlinear models and their complexity using techniques that are universal and have connections to historical and material aspects. Using the premise of a constant population that is uniformly mixed, a nonlinear compartmental model that depicts the movement between voter classes is taken into consideration. In the current work, we investigate the dynamical framework that supports the interactions between the three parties. It is discussed how rate change affects various metrics. The conditions for boundedness, stability, existence, and other dynamics are obtained. We derive the effects of generalizing the model in any order. The current study supports investigations into complex real-world issues and forecasts of necessary plans. © 2023 The Author(s
A Novel Study of Morlet Neural Networks to Solve the Nonlinear HIV İnfection System of Latently İnfected Cells
No full textThe aim of this study is to provide the numerical outcomes of a nonlinear HIV infection system of latently infected CD4+ T cells exists in bioinformatics using Morlet wavelet (MW) artificial neural networks (ANNs) optimized initially with global search of genetic algorithms (GAs) hybridized for speedy local search of sequential quadratic programming (SQP), i.e., MW-ANN-GA-SQP. The design of an error function is presented by designing the MW-ANN models for the differential equations along with the initial conditions that represent the HIV infection system involving latently infected CD4+ T cells. The precision and persistence of the presented approach MW-ANN-GA-SQP are recognized through comparative studies from the results of the Runge-Kutta numerical scheme for solving the HIV infection spread system in case of single and multiple trails of the MW-ANN-GA-SQP. Statistical estimates with ‘Theil's inequality coefficient’ and ‘root mean square error’ based indices further validate the sustainability and applicability of proposed MW-ANN-GA-SQP solver. © 2021 The Author
The apoptotic effects of silibinin on MDA-MB-231 and MCF-7 human breast carcinoma cells
No full textWOS: 000402150300005PubMed ID: 27402681Background: Silibinin is a bioactive flavonolignan extracted from milk thistle, known as Silybum marianum. Silibinin exerts strong antiproliferative, proapoptotic, and anti-inflammatory effects. Many studies have shown that silibinin inhibits experimentally induced malignancies of the liver, prostate, skin, and colon as well as promotes inhibition of the proliferation of cancer cell lines in vitro. This study aimed to investigate the effects of silibinin on the human breast carcinoma cell lines MDA-MB-231 and MCF-7 in monolayer and spheroid cultures. Method: The MDA-MB-231 and MCF-7 cell lines were cultured in both monolayer and spheroid cultures. Cells were treated with silibinin at 24, 48, and 72 h of incubation. The 5-bromo-2-deoxyuridine labeling index was used to determine the cells of the synthesis phase. Poly-ADP-ribose-polimerase immunohistochemical staining and the terminal deoxynucleotidyl transferase dUTP nick and labeling assay were used to determine the death of cells in both the monolayer and spheroid cultures. Results: An half maximal inhibitory concentration dose of silibinin in MDA-MB-231 and MCF-7 cells was 100 mu M/mL at 24, 48, and 72 h of incubation. Terminal deoxynucleotidyl transferase dUTP nick and labeling positive cells and active poly-ADP-ribose-polimerase were detected after treatment with silibinin in both the monolayer and spheroid cultures. The dead cell count was higher in the MDA-MB-231 and MCF-7 cell lines with silibinin applied than in the controls. Conclusions: Our study demonstrated that silibinin applications enhanced terminal deoxynucleotidyl transferase dUTP nick and labeling positive cells and active poly-ADP-ribose-polimerase in comparison to the control in both the monolayer and spheroid cultures.Mugla Sitki Kocman UniversityMugla Sitki Kocman UniversityThe author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The present study was supported by the Research Fund of Mugla Sitki Kocman University. Some parts of this manuscript were presented at the 5th International Congress on Cell Membranes and Oxidative Stress: Focus on Calcium Signaling and TRP Channels 9-12 September 2014, Isparta
An atypical bladder diverticulum presented with recurrent peritonitis: case report
No full textBladder diverticula develop from congenital detrusor muscle defect and frequently present with urinary tract infection, which occurs as a result of urinary stasis in the diverticula. Different clinical presentations, such as bladder outlet obstruction, cyanosis of the lower extremities, intestinal obstruction, ureteral obstruction (which may occur due to direct diverticular compression), and peritonitis due to spontaneous rupture of the diverticula, were reported previously. Here, we report a case with the diagnosis of bladder diverticulum that caused recurrent generalized peritonitis without perforation and mimicked perforated appendicitis
Inducible nitric oxide synthase and histopathological correlation in chronic viral hepatitis
No full textSummaryBackgroundChronic liver disorders represent a serious health problem. Nitric oxide (NO) synthesized by inducible nitric oxide synthase (iNOS) can function as an antimicrobial agent able to kill or reduce replication of microorganisms, and plays an important role in immune regulation. This study was undertaken to evaluate the expression of iNOS in chronic viral hepatitis and its relation to histopathology.MethodsThis study included 56 patients with chronic viral hepatitis (38 hepatitis B, 18 hepatitis C). There were 35 men and 21 women with a mean age of 38.6±21.731 years. A modified form of the histology activity index (HAI) designed by Ishak and colleagues was used to assess grading and staging of chronic viral hepatitis. The needle biopsy specimens were fixed in 10% formalin and routinely processed. Routine hematoxylin–eosin, periodic acid–Schiff, and reticulin staining, and iNOS immunoperoxidase technique were performed on paraffin-embedded tissues.ResultsWe demonstrated that all liver samples had a marked iNOS expression, with a diffuse distribution pattern. iNOS consistently labeled mononuclear cells infiltrating portal tracts in all samples. Statistical evaluation of data showed that the iNOS expression correlated with the HAI and fibrosis. Furthermore a correlation between iNOS and severity of disease was detected (r=0.772, p=0.000).ConclusionsFurther investigations are required to determine whether iNOS-related treatment protocols could be useful in reducing disease severity
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