85 research outputs found
Investigating the anti-inflammatory properties of curcuminoids, Carica papaya L. leaf extracts and the active compound phylloxanthobilin
author: Elif Nur Cömen, BSc.Zusammenfassung in deutscher SpracheMasterarbeit Universität Innsbruck 202
Investigating the anti-inflammatory properties of curcuminoids, Carica papaya L. leaf extracts and the active compound phylloxanthobilin
author: Elif Nur Cömen, BSc.Zusammenfassung in deutscher SpracheMasterarbeit Universität Innsbruck 202
Investigating the anti-inflammatory properties of curcuminoids, Carica papaya L. leaf extracts and the active compound phylloxanthobilin
author: Elif Nur Cömen, BSc.Zusammenfassung in deutscher SpracheMasterarbeit Universität Innsbruck 202
sj-docx-1-jpx-10.1177_23743735221103027 - Supplemental material for Do Patient Experiences Have Mediating Roles on Patient Loyalty?
Supplemental material, sj-docx-1-jpx-10.1177_23743735221103027 for Do Patient Experiences Have Mediating Roles on Patient Loyalty? by Tuncay Arslan, Z. Özge Çandereli, Okan Cem Kitapçi, Nur Şişman Kitapçi, Pınar Kiliç Aksu, Leyla Köksal, Elif Özge Özdamar, Meral Yay, Şule Ecevit Alpar and Gonca Mumcu in Journal of Patient Experience</p
Elective Cesarean Preserves Maternal-Fetal Redox Homeostasis, Whereas Emergency Cesarean Disrupts It: A Prospective Observational Study Delivery Mode and Oxidative Stress
Kirimli Yanik, Elif Ceren Nur/0009-0005-6636-0097Introduction: Oxidative stress is a key component of maternal-fetal physiology and varies with the mode of delivery. Labor induces hypoxia-reoxygenation cycles that elevate reactive oxygen species, whereas elective cesarean section (CS) occurs in a controlled metabolic environment. Emergency CS combines labor-related hypoxia with acute surgical stress. Comprehensive comparisons of maternal and cord oxidative profiles across all delivery modes remain limited. Methods: This prospective observational study included 126 term singleton pregnancies categorized as elective CS (n = 46), emergency CS (n = 39), or vaginal delivery (n = 41). Maternal blood was collected immediately before delivery and cord blood after birth. Total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI), and paraoxonase-1 (PON-1) activity were measured using automated RelAssay methods; OSI was calculated as (TOS/TAS)x100. Neonatal outcomes included Apgar scores and NICU admission. Group comparisons used ANOVA, Kruskal-Wallis, and chi-square tests, with ANCOVA adjusting for gestational age, maternal weight, diabetes, hypothyroidism, preeclampsia, and ASA use. Results: Baseline characteristics were comparable. Emergency CS had lower Apgar-1 scores and higher NICU admission. Maternal OSI (p = 0.002) and PON-1 (p = 0.004) differed significantly, with elective CS showing the most favorable profile. Cord TOS (p < 0.001), OSI (p < 0.001), and PON-1 (p = 0.001) were also highest in emergency CS. Delivery mode independently predicted maternal OSI and PON-1, and cord TOS, OSI, and PON-1 (all p < 0.01). Discussion: The pronounced oxidative shifts observed in emergency CS likely reflect the cumulative impact of prolonged labor, fetal distress, and abrupt surgical intervention. Elective CS, by avoiding labor-induced hypoxia and metabolic exhaustion, preserves a more balanced maternal-fetal redox environment. The parallel maternal and cord responses underscore the sensitivity of the fetoplacental unit to intrapartum oxidative changes. These findings clarify mechanistic differences between delivery modes and highlight redox status as a potential peripartum biomarker. Conclusion: Elective CS preserves maternal-fetal redox homeostasis, whereas emergency CS results in significant oxidative disruption and poorer neonatal adaptation. These findings support the potential use of oxidative stress markers as adjunct indicators of acute intrapartum stress when interpreted alongside established clinical parameters
Evaluation of the historical settlement of Kilistra in the context of the traditional knowledge systems (TKS) for its sustainable conservation
Yüksek Lisans TeziGeleneksel bilgi sistemleri; belirli bir bölgedeki bir yerleşimin yerli sakinleri tarafından yüzyıllar boyunca geliştirilip korunan yerli bilgi, teknikler, değerler, gelenekler ve kurallardır. Bu sistemlerin iyi bir analizi sadece onların gelecek nesillere aktarılmasına yardımcı olmakla kalmaz, aynı zamanda yeni tasarımlara adaptasyon potansiyellerini de arttırır. Bu nedenle bu araştırma; Konya ilinde bulunan tarihi bir yerleşim olan Kilistra'daki geleneksel bilgi sistemlerinin bir yandan bilinirliğini artırmayı diğer yandan da bölgenin sürdürülebilir kalkınması ile ilişkisini kurmayı amaçlamaktadır. Çalışmanın yöntemini; anket çalışması, arşiv ve literatür araştırması, saha gözlemleri ve sözlü görüşmeler oluşturmaktadır. Çalışma, bölgenin özgün geleneksel bilgi sistemlerinin her geçen gün ortadan kalktığını ve yerleşimin özellikle kış dönemlerinde terkedilme tehdidi altında olduğunu bu nedenle de nitelikli alan yönetimi planlaması ile sürdürülebilir korunması gerektiğini göstermiştir. Dolayısıyla bu çalışma; yerleşimin özgün değerlerinin ortaya çıkarılması ve korunması, geleneksel bilgi sistemlerinin daha iyi anlaşılması, bölgenin tarihi dokusuna uygun nitelikli ve sürdürülebilir çözümler bulunması açısından önemlidir ve benzer yerleşimlere örnek teşkil edebileceği değerlendirilmektedir.Traditional knowledge systems are indigenous knowledge, techniques, values, customs, and ethical rules developed by the indigenous inhabitants of a settlement in a particular area and maintained throughout their lifetimes. A good analysis of these systems should help pass them on to future generations and look at their potential to adapt to new designs. For this reason, this research aims to raise awareness of traditional knowledge in Kilistra, a historical settlement in Konya province, on the one hand, and to establish its relationship with its sustainable development on the other. The main methods of the study include a questionnaire study, archival and literature research, field observations, and oral interviews. The study shows that the original traditional knowledge structures of the region are disappearing day by day and the settlement is under threat of abandonment especially in winter seasons, so it should be protected with the sustainable conservation of the protected area. Therefore, this study is considered important and exemplary research for similar settlements in terms of revealing and preserving the original values of the settlement, better preserving the traditional knowledge systems, preservation in accordance with the historical texture of the region and finding permanent solutions
The contribution of traditional knowledge systems to sustainable urban development: The case of the historic settlement of Sille
1161-1172Traditional Knowledge Systems (TKS) encompass the indigenous knowledge, techniques, values, customs, and ethics
developed and preserved by native inhabitants over centuries. Analyzing these systems helps transmit them to future
generations while enhancing their adaptability to contemporary designs. This research focuses on TKS in Sille, a historical
settlement in Konya, Türkiye, aiming to increase awareness and establish their connection with sustainable development.
Through archival and literature research, field observations, and interviews, the study identifies Sille’s traditional
construction techniques, cultural practices, and methods of food production and preservation. Findings reveal that these
practices are deeply tied to the region’s natural environment, including its climate, topography, and ecology. They also align
harmoniously with ancestral customs, traditions, and rituals. Despite their richness, Sille’s TKS face threats from
modernization and the pressures of increased tourism. With each passing day, unique elements of this heritage are being
lost, underscoring the urgent need for protection through qualified area management planning. This study highlights the
importance of documenting and preserving Sille’s TKS to safeguard its original values. By integrating this knowledge into
sustainable urban development strategies, the research also explores practical solutions compatible with the historic urban
fabric of the region. Overall, it emphasizes the potential of blending traditional wisdom with contemporary approaches to
address ecological and cultural challenges
Second-order theory of mind: thinking about thinking … about thinking
Preschoolers’ performance in the standard false belief task has been shown to be correlated with working memory and inhibitory control tasks. The Theory of Mind Mechanism (ToMM) account (Leslie, 1987; Leslie, 1992, 1994) posits that inhibition plays a role in the expression of theory of mind understanding (Leslie & Polizzi, 1998; Leslie, German, & Polizzi, 2005), and that the difference in performance between the ages of three and four can be explained by changes in children’s inhibitory control. There is also evidence that children can track multiple minds each with distinct false beliefs (Cheng, 2018). Specifically, they found that 4-year-olds can track up to 4 minds, showing adequate working memory resources at the age of 4. In another vein, an unexplored part of theory of mind research is on how children understand second order false beliefs (FB): “Anne believes that Sally believes the marble is in the box.”. Whereas initial studies suggested success around 6.5-7 years of age (Perner & Wimmer, 1985), simplified versions found success around the age 5.5 by reducing processing demands (Sullivan et al., 1994). It is still an open question what specifically those processing demands are. The initial aim of the current project is to replicate Cheng’s (2018) findings, and as the main aim, we planned on testing children by manipulating two demand factors: working memory (by including more than a single agent in the story), and inhibitory control (by having low and high demand levels). However, the current project only contains data for 4- and 5-year-olds’ performance in a double agent low inhibitory demand task. The results from Experiment 1 shows that five-year-olds were more successful compared to four-year-olds in both first and second-order false belief understanding. However, due to concerns about certain details of the stimuli and the delivery of the task in Experiment 1, Experiment 2 was conducted. Results from Experiment 2 were almost identical to Experiment 1, showing that the potential limitations thought to be affecting results in Experiment 1 were not influential in children’s performance. Furthermore, both in Experiment 1 and 2 the results show a pattern that when children are successful in the first order questions, they also tend to be successful in the second order question. Further directions and need for testing a high inhibitory demand condition are discussedM.S.Includes bibliographical reference
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