18 research outputs found
Михал Чабала – очами сучасників
No full textMYCHAL CZABALA – OCZAMI WSPÓŁCZESNYCH
W artykule została podjęta próba analizy twórczości Mychala Czabali, rusińskiego malarza pochodzącego z Czabyn, który przez całe swoje życie zawodowe mieszkał w Preszowie i który swoją bogatą i znaczącą sztuką wyrażał podziw i miłość do narodu rusińskiego, jego przyrody i regionu. Inspirował go nie tylko sam region. To, co istotne w malarstwie Czabali, to wrażliwe postrzeganie tradycyjnej kultury ludowej Rusinów i jej twórczej siły wyrazu oraz inspiracja motywami pejzażowymi i figuratywnymi. Sztukę Mychala Czabali można określić jako apoteozę rusińskiego regionu i ludu. Już za życia artysty jego twórczość miała znaczący wpływ na tożsamość Rusinów zamieszkujących Słowację, ale także na całą Słowację, której był skłonny poświęcić swoje życie i karierę artystyczną. To, co wyróżnia Mychala Czabalę, to jego wielki wkład w słowacką sztukę, jak i również w malarstwo europejskie jako takie
Molecular phylogeny and speciation patterns in host specific monogeneans (Cichlidogyrus, Dactylogyridae) parasitizing cichlid fishes (Cichliformes, Cichlidae) in Lake Tanganyika
No full textsponsorship: The authors are grateful to C. Sturmbauer (University of Graz, Austria), W. Salzburger (University of Basel, Switzerland), D. Muzumani Risasi (CRH-Uvira, DR Congo) for their precious help with cichlid collection and identification; M. Reichard and R. Blaz. ek (Czech Academy of Sciences, Czech Republic) for their help with fish collection, dissection and providing us with the photographs of cichlid species during the field trip; A. Meyer (University of Konstanz, Germany), G. Banyankimbona (University of Burundi), the Schreyen-Brichard family (Fishes of Burundi) and T. Veall and O. R. Mangwangwa (Rift Valley Tropicals, Zambia) for sample collection and fish identification; P. Masilya Mulungula, T. Mulimbwa N'sibula, V. Lumami Kapepula, E. Bahane Byaragi, S. Kambale Mukeranya and F. Muterezi Bukinga (CRH-Uvira, DR Congo) for coorganising the field work and their scientific contribution on LT cichlids; S. Masova, V. Michalkova, E. R. ehulkova, I. Pr.ikrylova, L. Raisingerova, N. Kmentova, K. Civan. ova, E. Jirounkova, K. Koukalova, and M. Seifertova (Masaryk University, Brno, Czech Republic) for their help with fish dissection, parasite isolation and fixation and molecular laboratory analyses; and B. Egger, J. Rajkov and A. Anh-Thu Weber (University of Basel) for providing samples of Astatotilapia burtoni from Zambian systems. The first author thanks D. Ortiz Martinez (Masaryk University, Brno, Czech Republic) for stimulating discussions and constructive suggestions and criticisms related to phylogenetics. Finally, the authors would like to thank M. Gelnar for the continuous help he provided during this research. This research was funded by the Czech Science Foundation project no. P505/12/G112 -European Centre of Ichtyoparasitology (ECIP) and the Special Research Fund of Hasselt University (BOF20TT06, to M.P.M.V.). Fieldwork was partly supported by the Research Foundation-Flanders (FWO-Vlaanderen) (travel grants V.4.096.10.N.01 and K.2.032.08.N.01 to M.P.M.V., Research Programme G.0553.10) and a travel grant from the King Leopold III Fund for Nature Conservation and Exploration (to M.P. M.V.). Sampling was performed in accordance with mission statements no. 013/MNRST/CRHU/2010, 022/MINEURS/CRH-U/2013 and 031/MINRST/CRH-U/2016 from the Ministere de la Recherche Scientifique et Technologique-CRH-Uvira. The funders had no role in study design, data collection and analyses, decision to publish, or preparation of the manuscript. (Czech Science Foundation|P505/12/G112, Hasselt University|BOF20TT06, Research Foundation-Flanders (FWO-Vlaanderen)|V.4.096.10.N.01, Research Foundation-Flanders (FWO-Vlaanderen)|K.2.032.08.N.01, Research Foundation-Flanders (FWO-Vlaanderen)|G.0553.10, King Leopold III Fund for Nature Conservation and Exploration)status: Publishe
Transmission of parasites from introduced tilapias: a new threat to endemic Malagasy ichthyofauna
No full textInvasive species are a major threat to biodiversity. In Madagascar, one quarter of freshwater fish fauna consist of introduced species. The introduction of non-native species affects native biota by means of direct interactions but also through indirect interactions including those mediated by parasites, as parasites are usually co-introduced with their hosts. Almost nothing is known about the parasites co-introduced with their fish hosts into Madagascar and their potential impact on native endemic fish fauna. We studied the metazoan parasites of native and introduced cichlid fishes (and some non-cichlids) in the northern part of Madagascar. Using parasite data we evaluated the effect of fish introduced from mainland Africa on native Malagasy cichlid fauna. We documented the co-introduction into Madagascar of parasite species from mainland Africa and also probably from Eurasia. Malagasy cichlids and some other species living in sympatry with non-native cichlids acted as competent hosts for generalist parasites and also for host-specific parasites of African mainland cichlids. However, African mainland cichlids were not susceptible to infection by parasites specific to Malagasy cichlids. The different compositions of parasite communities and infection parameters in endemic and non-native cichlids in the regions investigated may be potentially explained by the different sources and timings of fish introductions. In addition, native endemic parasite fauna even seem to be outcompeted by introduced parasites, which cross the barriers of host specificity. The transmission of non-native parasites associated with the introduction of non-native freshwater fishes may represent a serious risk to endemic freshwater fish and parasite fauna in Madagascar.sponsorship: This study was funded by the Czech Science Foundation (Project No. P505/12/G112). MWPJ is supported by the Belgian Federal Science Policy Office (BRAIN-be Pioneer Project BR/132/PI/TILAPIA) and a BOF Reserve Fellowship from Hasselt University. We are grateful to our colleagues from Masaryk University, Brno-namely, Tomas. Pakosta and Kristyna Koukalova for help with fish sequencing and Iva Prikrylova for the determination of Gyrodactylus specimens. We also thank Yuriy Kvach from the Institute of Vertebrate Biology, Czech Academy of Science for the identification of Acanthogyrus tilapiae; Simona Georgieva from the Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, Czech Republic for her help with identification of digeneans; Nathan Vranken, Eva Decru and Maarten Van Steenberge of the Royal Museum for Central Africa (Tervuren, Belgium) for verification of a portion of the host specimens; Jeanne Rasamy Razanabolana, Roger Daniel Randrianiana, Sarah Rakotomamonjy and Natacha Rasozolaka (University of Antananarivo) and the Centre National de Recherches Oceanographiques at Nosy Be for help in the field; Sylvere Lalao Rakotofiringa for advice; Joel Ho Shing Lone for the possibility to use the field laboratory; and Leonel Anglier Jaofeno, the Director of the Parc Mont Passot, Nosy Be, who allowed us to collect fish in the Mont Passot lakes. We also thank Matthew Nicholls for English language revision of the manuscript. (Czech Science Foundation|P505/12/G112, Belgian Federal Science Policy Office (BRAIN-be Pioneer Project)|BR/132/PI/TILAPIA, BOF Reserve Fellowship from Hasselt University)status: Publishe
Pulmonary thromboembolism in congenital heart defects with severe pulmonary arterial hypertension
No full textAbstractIntroductionCongenital heart defect (CHD) with shunt can lead to severe, even irreversible pulmonary arterial hypertension (PAH); in extreme form to Eisenmenger syndrome (ES). Despite relatively good long-term survival, these patients often suffer from cyanosis and multisystemic dysfunction, where pulmonary artery thrombosis can be a potentially fatal complication. Together with bleeding these are the most frequent causes of non-cardiac death in patients with severe PAH due to CHD.Patients and methodsProspective study of 40 patients with severe PAH due to CHD (28 female/12 male, median age 41.5 years) was performed, with the aim to analyze the presence of pulmonary artery thrombosis and correlating anatomical and laboratory risk factors.ResultsPrevious thrombosis and/or thromboembolic event was found in 7 patients (17.5%). Significant differences in cyanotic vs non-cyanotic patients were in red blood count parameters: median hemoglobin level 195 vs 141 (p<0.0001), median erythrocytes count 6.62 vs 4.88×1012/l (p<0.0001), median hematocrit 0.58 vs 0.44 (p<0.0001). Laboratory findings causing increased risk for thrombosis were increased thrombocytes aggregation in 15 patients (37.5%), hypercoagulation in 5 patients (12.5%) and endothelial dysfunction in 8 patients (20%). Anatomical risk factor—severe pulmonary artery dilatation (>40mm in female and >45mm in male) was found in 19 patients (51.4%).ConclusionsPatients with severe PAH due to CHD represent a high-risk group for pulmonary artery thrombosis with morphological and flow pathology combined with secondary erythrocytosis and coagulation abnormalities. A relatively high incidence of platelet hyperaggregability shown in our study would propose that aspirin therapy might be considered in some highly selected patients with severe PAH due to CHD. Further studies though are needed to support this data
POSSIBILITIES OF USING UNCONVENTIONAL METHODS AND DIETARY SUPPLEMENTS TO AFFECT WEIGHT GAINS OF CALVES
No full textHealthy and strong individuals are fundamental in every cattle breeding. The aim of this study was to find out which of these given supplement had the best influence on calf weight gain in the early period after weaning to milk nutrition. This research was carried out in cooperation with the farm in. Calves were studied from March 2012 to February 2013. They were weaned into outdoor individual box after birth. There were added supplements into their ration in the first two weeks of life. Calves were partitioned according to the added supplement into three experimental groups and one control group. The first weight control of calves was after birth and the second weight control was at the age of thirty days. The average weight gain was calculated from the differences in these values. The best demonstrable effect was in the experimental groups with the average increment of 26.9 kilograms, then in the experimental group with the average increment of 26.1 kilograms. The last group was the Control one, there was not any change in the ration and their average increment was 23.5 kilograms. The results of the statistical evaluation was p = 0.0572 in the group, p = 0.2570 in the group and p = 0.2124 in the group versus the Control group. It can be concluded from the results of this study that calves had a positive reaction on the supplements added in the first days of life and these had a favourable effect on diarrhoea prevention. drugs and beneficially stimulate system and, in general, they have a positive effect on the physiological condition
Intraspecific morphological variation in Cichlidogyrus (Monogenea) parasitizing two cichlid hosts from Lake Tanganyika exhibiting different dispersal capacities
No full textsponsorship: The authors are grateful to many colleagues and friends who assisted with the sample collections during the fieldtrip in Burundi in 2013 and in the Democratic Republic of the Congo in 2016. We thank C. Sturmbauer and S. Koblmuller (University of Graz, Austria), W. Salzburger (University of Basel, Switzerland), D. Muzumani Risasi (CRH-Uvira) for their precious help with cichlid identification; M. Reichard and R. Blaz. ek (Czech Academy of Sciences, Czech Republic) for their help with fish collection, dissection and providing us the photographs of cichlid species during the fieldtrip; A. Meyer (University of Konstanz, Germany), G. Banyankimbona (University of Burundi) and the Schreyen-Brichard family (Burundi/Belgium) for the sample collection and fish identification; P. Masilya Mulungula, T. Mulimbwa N'sibula, V. Lumami Kapepula, E. Bahane Byaragi, S. Kambale Mukeranya and F. Muterezi Bukinga (CRH-Uvira) for co-organizing the field work and their scientific contribution on Tanganyikan cichlids; S.. Mas. ova', V. Micha'lkova', E. R. ehulkova', I. Pr.ikrylova', L. Raisingerova' and N. Kmentova' (Masaryk University, Brno, Czech Republic) for their help with fish dissection, parasite isolation and fixation. The first author thanks L. S. tarhova' Serbina (Masaryk University, Brno, Czech Republic) for stimulating discussions and constructive suggestions and critics related to the geomorphometry. The kind help of K. Civa' n. ova', E. Jirounkova', K. Koukalova', and especially M. Seifertova' (Masaryk University, Brno, Czech Republic), who provided the necessary background in genetics and an unconditional assistance in the molecular laboratory, is acknowledged. Finally, the authors would like to thank E. Verheyen, T. Backeljau, and all the colleagues working at the Royal Belgian Institute of Natural Sciences (RBINS, Brussels), M. Parrent from the Royal Museum for Central Africa (RMCA, Tervuren), T. Artois, M.W.P. Jorissen, L. Steenaerts and T. Van Dijck (Hasselt University, Diepenbeek, Belgium) for their kind hospitality and for the precious help they provided during the stay in Belgium. This research was funded by the Czech Science Foundation project no. P505/12/G112-European Centre of Ichtyoparasitology (ECIP) and C.R., M.V.S. and M.P.M.V. were further supported by standard project GA19-13573S. The funder had no role in study design, data collection and analyses, decision to publish, or preparation of the manuscript. (Czech Science Foundation|P505/12/G112, GA19-13573S)status: Publishe
Women leaders in Cardiology. Contemporary profile of the WHO European region
No full textAIMS: Women’s participation is steadily growing in medical schools, but they are still not sufficiently represented in cardiology, particularly in cardiology leadership positions. We present the contemporary distribution of women leaders in cardiology departments in the World Health Organization European region. METHODS AND RESULTS: Between August and December 2020, we applied purposive sampling to collect data and analyse gender distribution of heads of cardiology department in university/third level hospitals in 23 countries: Austria, Azerbaijan, Belgium, Bosnia-Herzegovina, Croatia, France, Germany, Greece, Italy, North Macedonia, Morocco, Poland, Portugal, Russia, Serbia, Slovakia, Slovenia, Spain, Switzerland, Tunisia, Turkey, Ukraine, and the UK. Age, cardiology subspecialty, and number of scientific publications were recorded for a subgroup of cardiology leaders for whom data were available. A total of 849 cardiology departments were analysed. Women leaders were only 30% (254/849) and were younger than their men counterpart (♀ 52.2 ± 7.7 years old vs. ♂ 58.1 ± 7.6 years old, P = 0.00001). Most women leaders were non-interventional experts (♀ 82% vs. ♂ 46%, P < 0.00001) and had significantly fewer scientific publications than men {♀ 16 [interquartile range (IQR) 2–41] publications vs. ♂ 44 (IQR 9–175) publications, P < 0.00001}. CONCLUSION: Across the World Health Organization European region, there is a significant gender disparity in cardiology leadership positions. Fostering a diverse and inclusive workplace is a priority to achieve the full potential and leverage the full talents of both women and men
Updated guidelines for gene nomenclature in wheat.
No full textKey message: Here, we provide an updated set of guidelines for naming genes in wheat that has been endorsed by the wheat research community. Abstract: The last decade has seen a proliferation in genomic resources for wheat, including reference- and pan-genome assemblies with gene annotations, which provide new opportunities to detect, characterise, and describe genes that influence traits of interest. The expansion of genetic information has supported growth of the wheat research community and catalysed strong interest in the genes that control agronomically important traits, such as yield, pathogen resistance, grain quality, and abiotic stress tolerance. To accommodate these developments, we present an updated set of guidelines for gene nomenclature in wheat. These guidelines can be used to describe loci identified based on morphological or phenotypic features or to name genes based on sequence information, such as similarity to genes characterised in other species or the biochemical properties of the encoded protein. The updated guidelines provide a flexible system that is not overly prescriptive but provides structure and a common framework for naming genes in wheat, which may be extended to related cereal species. We propose these guidelines be used henceforth by the wheat research community to facilitate integration of data from independent studies and allow broader and more efficient use of text and data mining approaches, which will ultimately help further accelerate wheat research and breeding. © 2023, The Author(s)
Introducing the International Comparable Corpus
No full textThis presentation introduces a new collaborative project: the International Comparable Corpus (ICC) (https://korpus.cz/icc), to be compiled from European national, standard(ised) languages, using the protocols for text categories and their quantities of texts in the International Corpus of English (ICE)
Genotype-phenotype associations in WT1 glomerulopathy
No full textWT1 mutations cause a wide spectrum of renal and extrarenal manifestations. Here we evaluated disease prevalence, phenotype spectrum, and genotype-phenotype correlations of 61 patients with WT1-related steroid-resistant nephrotic syndrome relative to 700 WT1-negative patients, all with steroid-resistant nephrotic syndrome. WT1 patients more frequently presented with chronic kidney disease and hypertension at diagnosis and exhibited more rapid disease progression. Focal segmental glomerulosclerosis was equally prevalent in both cohorts, but diffuse mesangial sclerosis was largely specific for WT1 disease and was present in 34% of cases. Sex reversal and/or urogenital abnormalities (52%), Wilms tumor (38%), and gonadoblastoma (5%) were almost exclusive to WT1 disease. Missense substitutions affecting DNA-binding residues were associated with diffuse mesangial sclerosis (74%), early steroid-resistant nephrotic syndrome onset, and rapid progression to ESRD. Truncating mutations conferred the highest Wilms tumor risk (78%) but typically late-onset steroid-resistant nephrotic syndrome. Intronic (KTS) mutations were most likely to present as isolated steroid-resistant nephrotic syndrome (37%) with a median onset at an age of 4.5 years, focal segmental glomerulosclerosis on biopsy, and slow progression (median ESRD age 13.6 years). Thus, there is a wide range of expressivity, solid genotype-phenotype associations, and a high risk and significance of extrarenal complications in WT1-associated nephropathy. We suggest that all children with steroid-resistant nephrotic syndrome undergo WT1 gene screening.Kidney International advance online publication, 8 January 2014; doi:10.1038/ki.2013.519
