1,455 research outputs found
Letter from Frederic L. Kirgis, U.S. National Park Service
No full textLetter from solicitor Frederic L. Kirgis on behalf of his clients filing claims in regards to the fire started on government-owned apartments in the Grand Canyon
Strategies for fertility preservation in young early breast cancer patients
No full textDiagnosis of breast cancer in young women poses a threat to fertility. Due to a recent trend of delaying pregnancy, an increasing number of breast cancer patients in reproductive age wish to bear children. Health care providers have the responsibility to know how to manage fertility issues in cancer survivors. Oncofertility counseling is of great importance to many young women diagnosed with cancer and should be managed in a multi-disciplinary background. Most of young breast cancer patients are candidate to receive chemotherapy, which could lead to premature ovarian failure. A baseline evaluation of ovarian reserve may help in considering the different fertility preservation options. The choice of the suitable strategy depends also on age, type of chemotherapy, partner status and patients' motivation. Various options are available, some established such as embryo and oocyte cryopreservation, some still experimental such as ovarian tissue cryopreservation and ovarian suppression with GnRHa during chemotherapy. An early referral to a reproductive specialist should be offered to patients at risk of infertility who are interested in fertility preservation. (C) 2014 Elsevier Ltd. All rights reserve
A Spin Wave Based Approximate 4:2 Compressor Seeking the most energy-efficient digital computing paradigm
No full textsponsorship: This work received funding from the European Union's Horizon 2020 research and innovation program within the Future and Emerging Technologies Open project Spin Wave Computing for Ultimately-Scaled Hybrid Low-Power Electronics, under grant 801055. It has also been partially supported by IMEC's industrial affiliate program on beyond-CMOS logic. Frederic Vanderveken acknowledges financial support from Flanders Research Foundation through grant 1S05719N. (European Union's Horizon 2020 research and innovation program within the Future and Emerging Technologies Open project Spin Wave Computing for Ultimately-Scaled Hybrid Low-Power Electronics|801055, IMEC's industrial affiliate program on beyond-CMOS logic, Flanders Research Foundation|1S05719N)status: Publishe
The Early History of the Fraser River Mines
No full textby Frederic W. Howay.Memoirs (Provincial Archives of British Columbia) ; 6
The Novels of Harold Frederic
No full textI do not intend to defend the obviously untenable thesis that Frederic was a great writer and is not appreciated because of the nature of his subject matter. The author of The Damnation of Theron Ware seldom shows any sign of genius. What Frederic does, and often in a rather workmanlike manner, is tell a story of small-town and country people in upper New York state. In his early works, Seth\u27s Brother\u27s Wife and The Lawton Girl, the author writes about things he knows and has done. The works written about the same time as the two mentioned have a delightful simplicity and naïveté, and incidentally come very close to the realistic tradition in the novel. The majority of Frederic\u27s later works are tinged with a pseudo-sophistication, an artiness which just does not belong, and these elements detract from such an otherwise good thing as The Damnation of Theron Ware
Integration and validation of the ex vivo human placenta perfusion model
No full textThe ex vivo human placenta perfusion model is an effective and non-invasive method to study transplacental passage of drugs and environmental compounds in humans. Due to many challenges and its high complexity it remains difficult to incorporate it routinely into laboratories.sponsorship: Frederic Amant is senior investigator of the Research Fund Flanders (F.W.O.). This project was supported by grants from F.W.O. and ERC 'CRADLE'. Kristel Van Calsteren received clinical research funding from the University Hospital Leuven (KOF, 2012-2015). (F.W.O., ERC 'CRADLE', University Hospital Leuven (KOF))status: Publishe
Noninvasive Prenatal Testing and Detection of Occult Maternal Malignancies
No full textsponsorship: F. Amant, research grant from Research Fund Flanders (FWO-Vlaanderen) (G080217N); J.R. Vermeesch, research grant from Research Fund Flanders (FWO-Vlaanderen) (G080217N). (Research Fund Flanders (FWO-Vlaanderen)|G080217N)status: Publishe
Danube River Development Strategy: Interim Report
No full textThe Danube is an essential Inland Water Transport (IWT) corridor, particularly for the hinterland connection for the Port of Constantza. This port became one of the largest and busiest ports on the Black Sea, due to its strategic location at the cross roads of Europe and Asia and due to its capacity to handle large volumes of different types of cargoes. With the ongoing economic reforms in Romania it is expected that the Port of Constantza will develop into a gateway for Eastern and Central Europe and efficient IWT hinterland connections are therefore required. The project "Danube River Development Strategy" aims to formulate a strategy and to define measures to increase the competitive position of IWT and to improve the navigability of the Romanian stretch of the Danube between the Iron Gates II and Giurgeni. The approach of the project can be characterized as strategy formulation to create a high capacity transport corridor at minimum investment costs. The project comprises two phases, i.e. River Status Phase and Strategy Development Phase. The first phase of the project has been completed in September 1994 with the submission of the River Status Report, which describes the present status of the Danube river followed by the generation of alternative development strategies for the Danube. In the second project phase selected strategies are analyzed followed by the selection of the preferred river development strategy. This Interim Report for the Strategy Development Phase includes the analyses of the various alternative development strategies. The report will be presented to and discussed with the Romanian authorities to select and further define the preferred development strategy. This preferred strategy will then be further analysed and reported in the Draft Final Report. The main objective of the Danube River Development Strategy project is to improve the navigation conditions of the Romanian section of the Danube between the Iron Gates II (rkm 869) and Giurgeni (rkm 239) in order to create a competitive IWT hinterland connection for the Port of Constantza. Various alternative development strategies have been considered. The strategies are rated on multiple criteria, where it appeared that all considered strategies are economically viable. The alternatives combi-c3 and combi-c4 appeared to have the best results. For description of all the alternatives we refer to the report.Danube River Development Strateg
Endometrial Cancer: From Biological to Clinical Approaches
No full textThis eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contac
In Vitro Assessment of the Expression and T Cell Immunogenicity of the Tumor-Associated Antigens BORIS, MUC1, hTERT, MAGE-A3 and Sp17 in Uterine Cancer
No full textWhile immunotherapy moved to the forefront of treatment of various cancers, it remains underexplored for uterine cancer. This might be due to the small patient population with advanced endometrial carcinoma and uterine sarcoma. Data about immunotherapeutic targets are scarce in endometrial carcinoma and lacking in uterine sarcoma.sponsorship: Frederic Amant is senior researcher for the Research Fund Flanders (F.W.O.). This work was financially supported by the Anticancer Fund (www.anticancerfund.org) and the associated Verelst Uterine Cancer Fund Leuven. We additionally acknowledge the Anticancer Fund for providing the scientific framework for this research. We also thank Ingrid Vandenput for helping us with getting familiar with microscopic evaluation and scoring of tissue slides. (Anticancer Fund, associated Verelst Uterine Cancer Fund Leuven)status: Publishe
- …
