University of New Mexico Digital Repository
Not a member yet
148775 research outputs found
Sort by
PANG
No full textPANG is mostly a memoir. It has three parts. The first third is part of a book-length memoir exploring the author\u27s relationship to art, people in art, and the apparatuses it exists within and under. Part two is composed of a cycle of autofiction short stories where transmasculine characters navigate masculinity, gender-affirming care, family, and anti-trans legislation in contemporary Florida. The final third of this creative dissertation is a collection of essays that explore embodiment and disembodiment, connection, and disconnection as it relates to the author\u27s experiences with the medical industrial complex, clothing, language, and American culture at large
The Museum of Clean: A Memoir
No full textThe Museum of Clean is a book-length memoir manuscript that explores what it means to clean and to be clean culturally. As the queer and trans child of Evangelical Christians who worked as janitors, I investigate my relationship to cleanliness, religion, and mental health–and the ways in which these values speak to whiteness and working-class identities, particularly in rural Idaho. This is explored alongside my decision to socially and medically transition and what that means for me physically and in my relationships with my family, my home, and the world at large
The Walking
No full textThe Walking is a book-length memoir manuscript that explores internalized misogyny, healing, and, of course, walking. In it, I write about the nearly 10,000 miles I’ve traveled on foot in the last decade, including thru-hikes of the Pacific Crest Trail, Continental Divide Trail, and Appalachian Trail. Against these backdrops, I explore what it means to be a woman in a hypermasculine space, including questions of healing, adventure, competition, and consent
THE EFFECT OF PERCUSSION THERAPY (THERAGUN™) ON MUSCLE SORENESS AND STRENGTH AFTER STRENUOUS EXERCISE
No full textThe study investigated the effects of percussion therapy using a Theragun™ device on markers of muscle damage following eccentric exercise. Eleven highly trained participants specializing in power performance (6 males, 5 females; age: 23 ± 6 years; height: 174.4 ± 11.7 cm; weight: 72.3 ± 13.9 kg) were randomly assigned to either percussion treatment (T) or sham treatment (S) groups. Participants performed 10 sets of 10 maximal effort lengthening contractions of the hamstring muscles followed by 2 minutes of one of the two treatment options. Muscle soreness, range of motion (ROM), single-leg broad jump distance, isokinetic strength, and serum creatine kinase activity were assessed at baseline, immediately post-exercise, post-treatment, and 24-, 48-, and 72-hours post-exercise. No significant group differences were observed throughout the study. These findings suggest that percussion therapy may not provide meaningful benefits for reducing muscle soreness, improving ROM or strength and functional performance outcomes following eccentric exercise
Vaccines Addressing Tau Pathology and Neuroinflammation in Alzheimer\u27s Disease and Related Dementias
No full textAlzheimer’s disease and related dementias (ADRD) are a devastating group of diseases and a leading cause of death worldwide. There are no therapeutics for ADRD to prevent, stop, or reverse disease progression. Thus, there is a need for the development of novel therapies. Vaccines offer the potential to generate long-lasting and specific antibody responses against their target while being cheaper and more accessible than monoclonal antibody therapies, allowing us to harness our own immune system to fight these diseases. We developed and characterized novel vaccines targeting pathological tau and the inflammasome complex, two key drivers of ADRD, in pre-clinical animal models. These vaccines can reduce ADRD brain pathology, including tau accumulation and neuroinflammation, and rescue cognitive deficits, without adverse events. These findings support future clinical investigations of these novel vaccines for the prevention and treatment of ADRD in humans
The Role of Gender and Salient Social Identities in Producing Vulnerability and Maladptation to Flooding in Koraso, Berekum, Ghana
No full textThis paper highlights how social identities like polygamy, illiteracy, and ethnicity hinder rural women farmers in Ghana from adapting to climate change. It advocates for an intersectional approach to address these challenges, moving beyond simplistic gender binaries. Using qualitative interviews (n=49) in a flood-prone village in Berekum, Ghana, the study reveals how these identities intersect with gender roles and colonial legacies, exacerbating vulnerability. It bridges Black feminist thought with climate change, an underexplored area, offering insights into climate change and environmental studies, as well as Black feminist scholarship. This research urges a reevaluation of how we understand climate change in relation to race, gender, and other social identities
IMMUNE CELL BALANCE IN CHRONIC HYPOXIA INDUCED PULMONARY HYPERTENSION
No full textChronic hypoxia (CH), caused by sleep apnea, chronic obstructive pulmonary disease, or high-altitude exposure, leads to pulmonary hypertension (PH). The pathogenesis of CH-induced PH has a number of hallmarks, including phenotypic changes in the pulmonary smooth muscle cells, arterial wall thickening, enhanced vasoreactivity, and inflammation around the pulmonary arteries. Utilizing a T regulatory (Treg) cell lineage tracking mouse model, this dissertation sought to further establish the importance of Treg and T helper 17 (TH17) cell balance in CH-induced PH. We demonstrated that Treg number and suppressive capacity decrease, TH17 cells increase, and Treg-to-TH17 cell transition occurs following exposure to hypoxia. We also show evidence that inducing tolerance to collagen type V (col V), a known self-antigen, attenuates indices of CH-induced PH. Altogether, this work further elucidates the mechanisms of the inflammatory response and possible therapeutic targets for preventing and treating CH-induced PH
Powering Up Clinical Scholarship in Shiprock Family Medicine
No full textThis presentation is designed for Shiprock–UNM Family Medicine residents and faculty, focusing on developing practical clinical scholarship skills within a full-spectrum family medicine context.Note-20250116.docx+1 Key topics include research question formation (PICOT, FAC Rubric), navigation of core clinical resources (PubMed, EMBASE, CINAHL, ClinicalKey, UpToDate, HSLIC LibGuides), advanced literature search techniques (Boolean operators, truncation, wildcards, proximity operators, subject headings), strategies for capturing search strategies and documenting basic search methods, use of full-text access tools (LibKey Nomad, proxy authentication, interlibrary loan and document delivery), introduction to critical appraisal tools (CASP, JBI, PRISMA-S), and an overview of publishing supports (Zotero, ORCID, UNM Digital Repository, open access considerations).Note-20250116.docx+1 The session aims to equip family medicine residents in Shiprock with foundational skills to connect everyday clinical questions to the literature, engage in small-scale scholarly activities, and effectively use HSLIC educational and research support services.https://digitalrepository.unm.edu/hslic-posters-presentations/1217/thumbnail.jp
