180,317 research outputs found
The International Concordia Explorer Telescope (ICE-T): an Ultimate Transit-Search Experiment for Dome C
No full textICE-T is a fully robotic telescope for astrophysics and atmospheric research for the Antarctic station Concordia at Dome C. ICE-T consists of two 60cm optical ultra-wide-field Schmidt telescopes and one 18cm narrow-field Maksutov spectrophotometric telescope on a single mount. The dual 60cm will be mainly used for a transit search due to extrasolar planets while the 18-cm will be used for measuring aerosol optical depths. ICE-T is a team effort of the German Alfred-Wegener-Institute for Polar Research, the Italian Universities of Padova and Perugia, the INAF Observatory Catania, and the Catalonian IEEC in Barcelona, Spain, and the AIP with collaboration from the University of New South Wales, Australia and the University of St Andrews, U.K
Pedro Afonso
No full textPedro Afonso is a Jewish rabbi from Huesca (Aragon) who lived between the middle of the 11th century (c. 1062) and the first half of the 12th century (c. 1140). He choose to convert to Christianity and it seems that he was baptized by the king of Aragon, Afonso the Batalhador, from whom he received the name, in addition to the first name of Peter, the saint of the day. Author of a wide-ranging work and polemicist who radically changed the terms of the debate between Judaism and Christianity in the 12th century. Firstly, it revealed the role of Jewish oral law, the so-called Talmud, which in its view distanced the Jews from the revelation common to both religions, which would be the authority (auctoritas) and which was the basis of the controversy until then; secondly, in his own way, he brought allegedly scientific and rationalist contributions based on philosophy and the sciences of the time (ratio) to the controversy; and in a third contribution he reflected on the effective legality of the Jewish presence in the domains of Christianity, which was based on the terms of tolerance proclaimed by Augustine of Hippo who envisioned in the near future a role of the Jews in Christian eschatology, as they would be converted at the end of time , in the Millennium. Thus he placed contemporary Jews as a kind of heretics, who distanced themselves from revelation. Pedro Afonso is a milestone in the worsening of the Jewish condition in the medieval West.Pedro Afonso é um rabino judeu de Huesca (Aragão) que viveu entre meados do século XI (c. 1062) e a primeira metade do século XII (c. 1140). Optou por se converter ao Cristianismo e ao que tudo indica foi batizado pelo rei de Aragão, Afonso o Batalhador, de quem recebeu o nome, além do prenome de Pedro, o santo do dia. Autor de ampla obra e polemista que alterou radicalmente os termos do debate entre o Judaísmo e o Cristianismo, no século XII. Em primeiro lugar revelou o papel da lei oral judaica, o assim denominado Talmude, que a seu ver distanciava os judeus da revelação comum ás duas religiões, que seria a autoridade (auctoritas) e que era a base da polêmica até então; em segundo lugar, à sua maneira, trouxe aportes pretensamente científicos e racionalistas embasados na filosofia e nas ciências da época (ratio) para a polêmica; e num terceiro aporte refletia sobre a efetiva legalidade da presença judaica nos domínios da Cristandade, que se baseava nos termos da tolerância apregoada por Agostinho de Hipona que vislumbrava num futuro próximo uma função dos judeus na escatologia cristã, pois estes se converteriam no final dos tempos, no Milênio. Assim colocava os judeus contemporâneos como uma espécie de hereges, que se distanciaram da revelação. Pedro Afonso é um marco na agudização da condição judaica no ocidente medieval
Pedro Afonso
No full textPedro Afonso é um rabino judeu de Huesca (Aragão) que viveu entre meados do século XI (c. 1062) e a primeira metade do século XII (c. 1140). Optou por se converter ao Cristianismo e ao que tudo indica foi batizado pelo rei de Aragão, Afonso o Batalhador, de quem recebeu o nome, além do prenome de Pedro, o santo do dia. Autor de ampla obra e polemista que alterou radicalmente os termos do debate entre o Judaísmo e o Cristianismo, no século XII. Em primeiro lugar revelou o papel da lei oral judaica, o assim denominado Talmude, que a seu ver distanciava os judeus da revelação comum ás duas religiões, que seria a autoridade (auctoritas) e que era a base da polêmica até então; em segundo lugar, à sua maneira, trouxe aportes pretensamente científicos e racionalistas embasados na filosofia e nas ciências da época (ratio) para a polêmica; e num terceiro aporte refletia sobre a efetiva legalidade da presença judaica nos domínios da Cristandade, que se baseava nos termos da tolerância apregoada por Agostinho de Hipona que vislumbrava num futuro próximo uma função dos judeus na escatologia cristã, pois estes se converteriam no final dos tempos, no Milênio. Assim colocava os judeus contemporâneos como uma espécie de hereges, que se distanciaram da revelação. Pedro Afonso é um marco na agudização da condição judaica no ocidente medieval
Conus vulcanus Tenorio et Afonso, 2004
No full textCatálogo do Museo de Historia Natural USC. n. inventario 10014
Carta com notícias do reino de França e novidades sobre a armada de Afonso de Albuquerque [c. 1513]
No full text[c. 1513, s.l.] Carta enviada ao Rei de Portugal acerca da entrega dos gatos e papagaios ao Rei e Rainha de França e outras novidades do reino. Inclui também notícia da armada de Afonso de Albuquerque. [c. 1513, s.l.] Letter sent to the King of Portugal regarding the delivery of cats and parrots, as well as other novelties from the kingdom, to the King and Queen of France. It also includes news of Afonso de Albuquerque’s fleet.publishersversionpublishe
Gas-phase doubly charged complexes of cyclic peptides with copper in +1, +2 and +3 formal oxidation states: formation, structures and electron capture dissociation
No full textCopper complexes with a cyclic D-His-β-Ala-L-His-L-Lys and all-L-His-β-Ala-His-Lys peptides were generated by electrospray which were doubly charged ions that had different formal oxidation states of Cu(I), Cu(II) and Cu(III) and different protonation states of the peptide ligands. Electron capture dissociation showed no substantial differences between the D-His and L-His complexes. All complexes underwent peptide cross-ring cleavages upon electron capture. The modes of ring cleavage depended on the formal oxidation state of the Cu ion and peptide protonation. Density functional theory (DFT) calculations, using the B3LYP with an effective core potential at Cu and M06-2X functionals, identified several precursor ion structures in which the Cu ion was threecoordinated to pentacoordinated by the His and Lys side-chain groups and the peptide amide or enolimine groups. The electronic structure of the formally Cu(III) complexes pointed to an effective Cu(I) oxidation state with the other charge residing in the peptide ligand. The relative energies of isomeric complexes of the [Cu(c-HAHK+H)] 2+ and [Cu(c-HAHK-H)] 2+ type with closed electronic shells followed similar orders when treated by the B3LYP and M06-2X functionals. Large differences between relative energies calculated by these methods were obtained for open-shell complexes of the [Cu(c-HAHK)] 2+ type. Charge reduction resulted in lowering the coordination numbers for some Cu complexes that depended on the singlet or triplet spin state being formed. For [Cu(c-HAHK-H)] 2+ complexes, solution H/D exchange involved only the N-H protons, resulting in the exchange of up to seven protons, as established by ultra-high mass resolution measurements. Contrasting the experiments, DFT calculations found the lowest energy structures for the gas-phase ions that were deprotonated at the peptide C α positions. © 2012 John Wiley & Sons, Ltd
Conus atlanticoselvagem Afonso et Tenorio, 2004
No full textCatálogo do Museo de Historia Natural USC. n. inventario 10009
Cortisol response and immune-related effects of Atlantic salmon (Salmo salar Linnaeus) subjected to short- and long-term stress
No full textIt is generally considered that stress causes decreased immune function in fish. In this study we examined in Atlantic salmon (Salmo salar Linnaeus) the effects of both short- (a single 15 s out of water) and long-term (4 weeks of daily handling 15 s out of water) stress on plasma cortisol (free and total) and glucose levels, expression of interleukin-1\u3b2 (IL-1\u3b2) and survival of head kidney (HK) macrophages under culture with Aeromonas salmonicida. In the short-term study, samples were collected prior to the application of the stressor, and at 1, 3, 6, 12 and 24 h post stress. Free and total plasma cortisol levels and the percentage of free cortisol increased significantly in the stressed group at 1 and 3 h post stress. Plasma glucose levels were significantly higher than those of control fish at 1, 3 and 6 h post stress. Constitutive expression of IL-1\u3b2 in macrophages isolated from head kidneys in stressed fish was significantly higher at 1 and 3 h post stress. However, lipopolysaccharide (LPS) stimulated expression of IL-1\u3b2 in HK macrophages, exhibited significantly higher fold increases in unstressed fish compared to stressed fish. In the long-term study, with the exception of an increase in plasma glucose levels at 1 week, there were no significant differences in stress parameters between groups. There was a significantly higher constitutive IL-1\u3b2 expression in macrophages isolated from stressed fish over the first 2 weeks. At weeks 1, 2 and 3 the magnitude of IL-1\u3b2 response of isolated HK macrophages to LPS stimulation was reduced in >90% of the stressed fish. At 4 weeks there was no significant difference in inducible IL-1\u3b2 expression between the groups. Macrophages isolated from stressed fish also showed significantly decreased survival when exposed to A. salmonicida. This study shows a clear pattern from repeated handling stress, whereby effects on immune cells begin with increased constitutive expression of IL-1\u3b2, followed by decreased stimulation of leucocytes by extracellular antigen, and finally decreased leukocyte survival when exposed to A. salmonicida. The implications of these changes in the immune system will be discussed with respect to the use of classical indicators of stress to predict possible effects on the immune system of fish.Peer reviewed: YesNRC publication: Ye
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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