13,936 research outputs found
A connection between two nonparametric tests for perfect ranking in balanced ranked set sampling
No full textIn this note, we show that an extension of a test for perfect ranking in a balanced ranked set sample given by Li and Balakrishnan (2008) to the multi-cycle case turns out to be equivalent to the test statistic proposed by Frey et al. (2007). This provides an alternative interpretation and motivation for their test statistic
On a system of nonlinear wave equations with the Kirchhoff-Carrier and Balakrishnan-Taylor terms
No full textsummary:We study a system of nonlinear wave equations of the Kirchhoff-Carrier type containing a variant of the Balakrishnan-Taylor damping in nonlinear terms. By the linearization method together with the Faedo-Galerkin method, we prove the local existence and uniqueness of a weak solution. On the other hand, by constructing a suitable Lyapunov functional, a sufficient condition is also established to obtain the exponential decay of weak solutions
Emerging Applications of Novel Nanoparticles (Ed. by N Balakrishnan)
No full textThis book is a comprehensive and modern guide on emerging nanoparticles and their diverse applications in engineering, medicine, food safety, transportation, energy, agriculture, and environmental sustainability. Written by leading researchers from all over the world, it is designed to cover the full range of nanoparticles as well as provide in-depth detail regarding their development, characterization, processing, and synthesis. The book is divided into two sections: the first covers the development of advanced nanoparticles and the second is dedicated to their variety of cutting-edge applications. The authors also cover the unique properties and green synthesis of nanoparticles as well as their use as nanobiosensors, nanopesticide, nanofertilizer, and as energy storage and conversion devices, just to name a few. This book provides readers with insight onto the broad scope of computational, theoretical, and experimental research on novel nanoparticles and their applications. It is ideal for both young and experienced researchers and industry professionals in the field of nanotechnology
Globalisasi dan syarikat multinasional: impak kepada kesatuan sekerja / Balakrishnan Parasuraman and Profesor Dr Virgel Binghay
No full textHari Pekerja tahun 2002 adalah hari yang penting bagi golongan pekerja dan kesatuan sekerja. 1 Mei 2002 adalah hari yang paling bahagia dan diraikan oleh golongan pekerja dan juga kesatuan sekerja dari seluruh dunia. Oleh itu, pihak majikan,kesatuan sekerja, para pekerja dan juga kerajaan perlu mengimbas kembali segala perkara yang berlaku dalam abad ke-20 yang Iepas. Abad ke-21 ini juga menandakan abad yang paling mencabar kepada kesatuan sekerja kerana beberapa fenomena baru berlaku seperti sindrom globalisasi, kepesatan syarikat multinasional, konsep fleksibiliti di tempat kerja, pekerja sambiIan, kesan teknologi (Balakrishnan 2001b; Ray Markey 2001, Balakrishnan dan Goodijk 2002 a), dan kemerosotan , keahlian kesatuan sekerja kebangsaan (Jackson 1991; Anil Verma 2002; Manfred Weiss 2002; Gatchalian 2000, Binghay 2002; Saini 1997) Semua isu ini perlu diambilkira oleh kesatuan sekerja dan golongan pekerja dalam menghadapi alaf ini. Oleh itu, perjuangan dan tanggungjawab kesatuan sekerja terhadap kebajikan pekerja amat berat sekali. Fokus perbincangan kertas kerja ini ialah membincangkan beberapa sindrom globalisasi melalui perkembangan syarikat multinasional dan kesannya terhadap kesatuan seketja kebangsaan. Beberapa kajian kes sama ada dari negara maju atau negara Dunia Ketiga akan diberi perhatian dalam kertas kerja ini
A generalization of the Balakrishnan skew-normal distribution
No full textThe skew-normal distribution belongs to a family of distributions which includes the normal distribution along with an extra parameter to regulate skewness. Azzalini [Azzalini A., 1985. A class of distributions which includes the normal ones. Scandinavian Journal of Statistics 12, 171-178] was the first to introduce the skew-normal distribution and studied some of its properties. Balakrishnan [Balakrishnan, N., 2002. Discussion of "skewed multivariate models related to hidden truncation and/or selective reporting". Test 11, 37-39], as a discussant of Arnold and Beaver [Arnold, B.C., Beaver, R.J., 2002. Skewed multivariate models related to hidden truncation and/or selective reporting (with discussion). Test II, 7-54], later proposed a generalization of this distribution. In this paper, we introduce a new generalization of the Balakrishnan skew-normal distribution by explaining some important properties of this distribution. Also, we have described three methods for constructing this distribution. Finally, its multivariate extension has been presented.
CA1 Neurons Acquire Rett Syndrome Phenotype After Brief Activation of Glutamatergic Receptors: Specific Role of mGluR1/5
No full textRett syndrome (RTT) is a neurological disorder caused by the mutation of the X-linked MECP2 gene. The neurophysiological hallmark of the RTT phenotype is the hyperexcitability of neurons made responsible for frequent epileptic attacks in the patients. Increased excitability in RTT might stem from impaired glutamate handling in RTT and its long-term consequences that has not been examined quantitatively. We recently reported (Balakrishnan and Mironov, 2018a,b) that the RTT hippocampus consistently demonstrates repetitive glutamate transients that parallel the burst firing in the CA1 neurons. We aimed to examine how brief stimulation of specific types of ionotropic and metabotropic glutamate receptors (GluR) can modulate the neuronal phenotype. We imaged glutamate with a fluorescence sensor (iGluSnFr) expressed in CA1 neurons in hippocampal organotypic slices from wild-type (WT) and Mecp2-/y mice (RTT). The neuronal and synaptic activities were assessed by patch-clamp and calcium imaging. In both WT and RTT slices, activation of AMPA, kainate, and NMDA receptors for 30 s first enhanced neuronal activity that induced a global release of glutamate. After transient augmentation of excitability and ambient glutamate, they subsided. After wash out of the agonists for 10 min, WT slices recovered and demonstrated repetitive glutamate transients, whose pattern resembled those observed in naïve RTT slices. Hyperpolarization-activated (HCN) decreased and voltage-sensitive calcium channel (VSCC) currents increased. The effects were long-lasting and bigger in WT. We examined the role of mGluR1/5 in more detail. The effects of the agonist (S)-3,5-dihydroxyphenylglycine (DHPG) were the same as AMPA and NMDA and occluded by mGluR1/5 antagonists. Further modifications were examined using a non-stationary noise analysis of postsynaptic currents. The mean single channel current and their number at postsynapse increased after DHPG. We identified new channels as calcium-permeable AMPARs (CP-AMPAR). We then examined back-propagating potentials (bAPs) as a measure of postsynaptic integration. After bAPs, spontaneous afterdischarges were observed that lasted for ∼2 min and were potentiated by DHPG. The effects were occluded by intracellular CP-AMPAR blocker and did not change after NMDAR blockade. We propose that brief elevations in ambient glutamate (through brief excitation with GluR agonists) specifically activate mGluR1/5. This modifies CP-AMPAR, HCN, and calcium conductances and makes neurons hyperexcitable. Induced changes can be further supported by repetitive glutamate transients established and serve to persistently maintain the aberrant neuronal RTT phenotype in the hippocampus
Global existence and polynomial decay for a problem with Balakrishnan-Taylor damping
No full textsummary:A viscoelastic Kirchhoff equation with Balakrishnan-Taylor damping is considered. Using integral inequalities and multiplier techniques we establish polynomial decay estimates for the energy of the problem. The results obtained in this paper extend previous results by Tatar and Zaraï [25]
Large and detached eddy simulation of separated flow over 3D hill geometries with surface roughness to mimic flows over complex terrains
No full textWith the push to making wind power a significant contributor to the energy portfolio in the U.S. and Europe, there is considerable effort to deploy the currently available peta-scale computational resources to assess and improve well known simulation techniques, such as the large eddy simulation (LES) and detached eddy simulation (DES) techniques, to model the complex flows in wind farms, taken as a whole, as opposed to individual wind turbines. Simulating turbulent flows in wind farms, consisting of arrays of wind turbines, begins with the modeling and simulation of the atmospheric boundary layer (ABL) over complex terrain that is characterized by regions of separated flow with a high degree of turbulence anisotropy. Over the years there has been considerable work on applying LES and Reynolds Averaged Navier--Stokes (RANS) simulations over terrain geometries, such as the Askervein Hill, to understand turbulence closure models for flow over complex terrain. Such studies, however, have had limited success due to difficulties associated with the closure models in the near wall region of the flow. At the same time, turbulence simulations over \emph{canonical} geometries, such as the periodic and axisymmetric hills, have been shown to compare well with data obtained from laboratory scale experiments, where the inflow turbulence and boundary conditions are better characterized and defined respectively. In an effort to extend these canonical flows to be more representative of flows over complex terrain, this paper aims to present results of large and detached eddy simulations of separated flow over three dimensional hill geometries with roughness parametrization, with the objective of developing better closure models for flow over complex terrain
A test for multivariate skew-normality based on its canonical form
No full textA test to assess if a sample comes from a multivariate skew-normal distribution is proposed. The test statistic is obtained from the canonical form of the multivariate skew-normal distribution and its null distribution is derived. The power of the proposed test is evaluated through Monte Carlo simulations for different conveniently chosen alternatives. Finally, three numerical examples are presented for the purpose of illustration
A decomposition algorithm for local access telecommunications network expansion planning
No full textIncludes bibliographical references.Supported by a grant from GTE Laboratories, Inc., Waltham, Mass., and by a research award from the AT&T Foundation. Supported by a NATO Collaborative research grant. CRG 900281Anantaram Balakrishnan, Thomas L. Magnanti, Richard T. Wong
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