1,738,908 research outputs found
Ms. 941 - Carta di guardia 1v
No full textContiene due note di mano di Riccardo Perli (1832-1907), che dal 1873 fu sottobibliotecario della Biblioteca Universitaria di Padova e successivamente, tra il 1903 e il 1905, reggente della stessa.
La prima nota riporta: "Justiniani Imper. Digestorum seu Pandectarum libri 1 usque ad 23 inclus. et pars libri 24. / Digestum vetus / Precedit Introductio De ratione et methodo iuris docendi ad antecessores."
La seconda nota recita: "Il presente Cod. Mss. segnato col n°. 941 fu dato a prestito per quattro mesi al Prof. presso l\u27Università di Berlino Dr. Mommsen, dietro interessamento (15 novembre 1864) della R. Legazione di Prussia a Vienna. Vedi Protocol. di questa R. Biblioteca Busta 38.9".
Il manoscritto fu spedito a Theodor Mommsen in data 28 novembre 1864. Il grande critico e giurista tedesco se ne servì per la realizzazione della sua \u27editio maior\u27 del Digesto (Digesta Iustiniani Augusti, recognovit adsumpto in operis societatem P. Kruegero, T. Mommsen, I-II, Berolini, 1868-1870). La durata del prestito non si limitò ai quattro mesi indicati nella nota, ma fu prorogata fino al termine dell’anno 1865. Il codice fece ritorno alla Biblioteca Universitaria di Padova il 22 febbraio 1866. Sono andati perduti i biglietti inviati da Mommsen, di cui è fatta menzione nella documentazione relativa a queste vicende. I documenti di interesse sono ABUP, II serie, Archivio-protocollo, Ba.19 n. 9 del 15 novembre 1864, con minuta di risposta e ricevuta di impostazione; n. 38 del 2 marzo 1865; n. 60 del 10 luglio 1865; Ba.20, n. 47 del 22 febbraio 1866.
Sul prestito del ms. 941 a Theodor Mommsen, v. M. MILANI, Il ms. 941 della Biblioteca Universitaria di Padova e l\u27editio maior del Digesto di Theodor Mommsen, in Digestum Vetus. Il manoscritto Padova, Biblioteca Universitaria, 941, a cura di P. Lambrini e M. Milani, Padova, 2020, 13-2
Exploring the Causal Role of miR-941 in Chronic Rhinosinusitis: Insights from Transcriptomics and Genomics
Full text linkFu Shu,1 Yaping Wang,2 Feng Zhang,2 Linglong Li,2 Dehong Mao2 1College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, 400000, People’s Republic of China; 2Department of Otorhinolaryngology, Yongchuan Chinese Medicine Hospital Affiliated to Chongqing Medical University, Chongqing, 400000, People’s Republic of ChinaCorrespondence: Dehong Mao, Department of Otorhinolaryngology, Yongchuan Chinese Medicine Hospital Affiliated to Chongqing Medical University, No. 2 Yingbin Avenue, Yongchuan District, Chongqing, 400000, People’s Republic of China, Tel +86-023-49822235, Email [email protected]: Despite significant advancements in the epigenetics of chronic rhinosinusitis (CRS), particularly in the domain of microRNA (miRNA), little is known about miRNAs that play a causal role in CRS. This study aims to identify miRNAs with a causal relationship to CRS and explore their potential clinical value and mechanisms in CRS.Methods: We conducted small RNA sequencing on blood and nasal samples to find miRNAs with consistent expression differences in CRS. These miRNAs were confirmed via qRT-PCR and assessed for clinical relevance through Spearman correlation and statistical analysis used to evaluate diagnostic accuracy. Bidirectional Mendelian randomization (MR, a genetic causal inference method) analyzed their causal links to CRS. Target genes of causally significant miRNAs were identified using miRWalk, and their mechanisms were explored through pathway enrichment and validation studies.Results: We identified differentially expressed miRNAs in blood and nasal tissues using a |log2(Fold Change)| > 0.58 and P-value < 0.05 threshold. Following False Discovery Rate correction, hsa-miR-941 was identified as an upregulated miRNA in both CRS patient samples. The experimental validation of miR-941 expression closely matched sequencing results. Spearman and statistical analysis associated miR-941 expression changes with CRS severity and diagnostic accuracy. Bidirectional MR demonstrated a significant association of miR-941 with CRS risk, without evidence of reverse causality. Target gene and Western blot assays suggested miR-941’s potential influence on CRS through the PI3K/AKT pathway.Conclusion: There is a positive causal relationship between hsa-miR-941 and CRS, making hsa-miR-941 a valuable target for the diagnosis and treatment of CRS. These findings position miR-941 as a valuable biomarker and therapeutic target, providing new opportunities for precision medicine in CRS treatment. miR-941 may exert its effects by modulating the PI3K/AKT signaling pathway.Keywords: chronic rhinosinusitis, transcriptomics, genomics, Mendelian randomization, miR-94
Resolución CPyGE Nº 31/2012. Refrenda y modifica Resolución Rectoral Nº 941/2012
No full textFil: Consejo de Programación y Gestión Estratégica (P). Universidad Nacional de Río Negro. Río Negro, ArgentinaResolución CPyGE Nº 31/2012. Refrenda y modifica los artículos 4º y 5º de la Resolución Rectoral Nº 941/2012 sobre puntos docente
El Tlacuache Núm. 941 (2020). 941 Año 19 (2020) julio. El Tlacuache
No full textComo sucede en diversas partes del mundo, en México, pensar en la memoria hoy en día es un tema sustancial porque permite que un sin fín de acercamientos y rescates al pasado, por ejemplo, que aventureros se adentren a regiones con vestigios arqueológicos, capillas y conventos religiosos.- Juan Bubernard por Alejandro Becerra Dubernard
miR-941 expression in PMNs.
No full textRelative expression of miR-941 in PMNs from healthy controls (HC, circles) and patients with granulomatosis with polyangiitis (GPA, squares). Expression of miR-941 is shown relative to the median value for the HC group. Horizontal lines indicate medians, and error bars depict interquartile ranges.</p
Claude Hicks, 941 11th Ave. R
No full textClaude Hicks, 941 11th Ave. R, Oct. 1939. no postmark, no addressee Label on original sleeve rfeads: Claude Hicks, 941 11th Ave (R), 10/39https://mds.marshall.edu/carl_photograph_collection/1102/thumbnail.jp
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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