1,724,496 research outputs found
CUSP9-9100
No full textExhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma using COMBImageDL.Label-free live-cell imaging data for the fourth replicate 384-well plate (barcode 9100) containing all plausible drug combinations of order 5-9 from the CUSP9 protocol as add-on to standard-of-care Temozolomide, using the human glioblastoma cell line M059K.22 grayscale images/frames of size 800x992 were acquired per experimental well, one every 4h for 84h, starting without treatment at 0h. The first and second channel of each frame contain the original grayscale pixel values, while the third one contains the binary segmentation map (foreground vs. background) generated with a modified version of the deep convolutional neural network architecture U-Net.M059K_190429_9100.xlsx: Excel file containing the experimental layout designed for plate 9100 and used to produce the corresponding transfer scheme for acoustic liquid dispension
Unit 9100 Style Dayliner
No full textA slide showing a "[u]nit 9100, another style of Dayliner which appear to be designed for mostly passengers, these high speed units carried about 50 passengers.
CUSP9-9100
No full textExhaustive in vitro evaluation of the 9-drug cocktail CUSP9 for treatment of glioblastoma using COMBImageDL.Label-free live-cell imaging data for the fourth replicate 384-well plate (barcode 9100) containing all plausible drug combinations of order 5-9 from the CUSP9 protocol as add-on to standard-of-care Temozolomide, using the human glioblastoma cell line M059K.22 grayscale images/frames of size 800x992 were acquired per experimental well, one every 4h for 84h, starting without treatment at 0h. The first and second channel of each frame contain the original grayscale pixel values, while the third one contains the binary segmentation map (foreground vs. background) generated with a modified version of the deep convolutional neural network architecture U-Net.M059K_190429_9100.xlsx: Excel file containing the experimental layout designed for plate 9100 and used to produce the corresponding transfer scheme for acoustic liquid dispension.THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOV
ICOM IC-9100 Bluetooth Control (IcomBTC)
No full textIcom IC-9100 Bluetooth Control tiene como finalidad poder controlar vía Bluetooth desde el Smartphone un transceptor de radioaficionado de la Marca ICOM, concretamente el modelo de alta gama IC-9100. Mediante su empleo podemos visualizar y cambiar a nuestra voluntad los parámetros más importantes del equipo, como son la frecuencia, el modo de modulación, la potencia, la ganancia de micrófono, transmitir, etc. El contexto de aplicación es el apasionando mundo de la radio, en su faceta de la radioafición. Los potenciales usuarios son por lo tanto radioaficionados que posean el equipo de referencia. Una anotación importante es que no solamente es interesante usarlo para operar nuestra radio desde la comodidad del sofá de nuestro salón o metidos en la bañera, sino que su uso puede ser de especial interés a personas con movilidad reducida.Icom IC-9100 Bluetooth Control té com a finalitat poder controlar via Bluetooth des del Smartphone un transceptor de radioaficionat de la Marca ICOM, concretament el model d'alta gamma IC-9100. Mitjançant la seva ocupació podem visualitzar i canviar a la nostra voluntat els paràmetres més importants de l'equip, com són la freqüència, la manera de modulació, la potència, el guany de micròfon, transmetre, etc. El context d'aplicació és l'apassionant món de la ràdio, en la seva faceta de la radioafició. Els potencials usuaris són per tant radioaficionats que posseeixin l'equip de referència. Una anotació important és que no solament és interessant usar-ho per operar la nostra ràdio des de la comoditat del sofà del nostre saló o ficats en la banyera, sinó que el seu ús pot ser d'especial interès a persones amb mobilitat reduïda.Icom IC-9100 Bluetooth Control has a powerful audience via Bluetooth from the smartphone a ham radio transmitter ICOM Brand, specifically the high-end model IC-9100. Using your mobile phone you can change and change the most important parameters of the equipment, such as frequency, modulation mode, power, microphone gain, transmit, etc. The context of application is the passionate world of radio, in its facet of ham radio. Potential users are therefore radio amateurs who own the reference equipment. An important note is that it is not only interesting to use it to operate our radio from the comfort of the sofa in our living room or in the bathtub, but its use may be of special interest to people with reduced mobility
Determining factors of the benefits derived from the implementation of EN 9100 standards
Full text linkIn Spain, as well as in the rest of the world, the aerospace sector is one of the most important. The
EN 9100 Standards (AS 9100 in America and SIAC 9100 in Asia), are a quality management system
for the aerospace industry derived from the ISO 9001 standard, that include the requirements
derived from the ISO 9001 and 83 specifi c additional requirements for the aerospace industry.
This research aims to begin covering the virtual lack of studies about the results arising from the
implementation of quality assurance standards in this sector. In particular, the objective of the
research involves analyzing whether the appearance of the various positive effects that may arise
as a result of implementing EN 9100 Standards is infl uenced by the following factors: a) size of the
company; b) implementation of EN 9100 seniority; c) prevailing type of motivation (external and/
or internal) to adhere to such standards. To that end, the research was addressed to the Spanish
aerospace sector, and the population subject to the investigation was defi ned by 317 companies.
A questionnaire was sent by postal mail and e-mail to the directors of quality of all the selected
companies, and a multiple linear regression model was applied to data from the 126 valid survey
responses. The results show that EN 9100 adherence seniority, as well as the prevailing type of
motivation (internal or external), are signifi cant variables for the appearance of positive effects
arising from the implementation of EN 9100, while the size of the company is non-signifi cant for the
emergence of such positive effects
Normgerecht im Flugzeugbau. Systematisch zur Zertifizierung nach EN 9100
No full textS.64In der Luftfahrt gelten höchste Sicherheitsanforderungen - nicht nur an Piloten, Flugsicherung und Kontrollen an Flughäfen, sondern auch an den Flugzeugbau. Durch die Norm EN 9100 können sich Unternehmen der Luftfahrtindustrie absichern, dass zugekaufte Komponenten den strengen Sicherheitsstandards entsprechen. Für die Zulieferer ist die Zertifizierung bislang allerdings sehr aufwendig, da die Liste der zu erfüllenden Kriterien umfangreich ist. Das Fraunhofer-Institut für Produktionstechnologie IPT in Aachen hat daher zusammen mit Access e.V. ein systematisches Vorgehen entwickelt, das die Zertifizierung nach EN 9100 erleichtert.Nr.4
Quality assurance in the aerospace industry : implementation of AS 9100 Quality Management Standard at an SME
Full text linkThesis (MScEng (Industrial Engineering))--University of Stellenbosch, 2011.ENGLISH ABSTRACT: South Africa has potential to grow extensively as a country supplying components to the global aerospace industry supply chains, as well as directly to OEMs like Airbus, Boeing and Cessna which are first tier suppliers. The economic crisis had a significant impact on the growth of small to medium sized enterprises (SMEs), also in aerospace companies. Before the recession, SMEs did not see the necessity to become certified with internationally accredited quality standards, because there were an abundance of business opportunities. In the current restricted business climate SMEs are increasingly realising the importance of certification.
The standard that aerospace companies need to comply with, is the AS 9100 standard. Compliance to AS 9100 was previously considered as a competitive advantage (order winner) but has become a necessary prerequisite (order qualifier) to be considered for a contract.
In the aerospace industry accountability, traceability, documentation and quality of parts are of critical importance. Quality of products according to specification is crucial as it has a profound effect on safety. The tendency in improving of a company's processes is to scale down on superfluous documentation. In the case of aerospace companies, this is an extremely challenging goal because traceability is of such crucial importance in this sector in terms of aircraft structural system and –operational integrity.
For the purpose of this study, a small to medium manufacturer of aircraft and defence system parts was studied and considered to be representative of the aerospace industry in South Africa. The research gap amongst SMEs was investigated by means of a case study at an SME in South Africa where an IT-based AS 9100 quality management system was designed, developed and implemented. The investigation includes the analysis of the research partner's quality documents, the steps in the design and development of the quality management system (QMS) and a description of the implementation thereof.
This study aims to provide the focus group (SMEs) with more knowledge when developing their quality management systems for implementation of the AS 9100 requirement to compete in the aerospace industry. It describes the historic background and current use of the AS 9100 standard as background.
The objective of the case study will be to determine the generic validity of the method to be able to implement AS 9100 at a small to medium sized aerospace supplier when using the same guidelines which are followed in this specific case.
The method's value and success are determined by means of an external audit (certification audit) of the company used in the case study. The method makes specific use of an IT-based infrastructure to facilitate the reduction of unnecessary documentation. Experiences gained by the author in applying AS 9100 to upgrade local manufacturing companies to aerospace suppliers to Volvo Aero Company in Sweden are briefly discussed as well as the validity to make use of these generic steps.AFRIKAANSE OPSOMMING: Suid-Afrika het die potensiaal om betekenisvol te groei as ʼn land wat komponente lewer aan internasionale lugvaart verskaffersnetwerke. Die ekonomiese krisis het 'n beduidende impak op die groei van klein tot mediumgrootte ondernemings gehad, asook in die lugvaart-industrie. Voor die resessie, het hierdie ondernemings nie die noodsaaklikheid om akkreditasie tot internasionale kwaliteitstandaarde te verkry na waarde geag nie, weens die genoegsame beskikbaarheid van sakegeleenthede. In die huidige ekonomiese klimaat word die belangrikheid van akkreditasie egter toenemend besef.
Die standaard waaraan maatskappye in die lugvaartindustrie moet voldoen is die AS 9100 kwaliteitsbeheerstelsel. Voorheen is die akkreditasie tot hierdie standaard gesien as ʼn mededingende voordeel wanneer daar getender is vir ʼn kontrak. Deesdae word dit as ʼn noodsaaklike voorvereiste beskou, voordat die besigheid se aansoek om ʼn kontrak te verkry eers oorweeg sal word.
In die lugvaartnywerheid is aanspreeklikheid, naspeurbaarheid en dokumentasie van kardinale belang. Die tendens in die verbetering van 'n maatskappy se prosesse is om af te skaal ten opsigte van onnodige dokumentasie. In die geval van lug- en ruimtevaartmaatskappye, is dit 'n uiters uitdagende doel, omdat naspeurbaarheid gedurende die komponent se leeftyd van deurslaggewende belang is in hierdie sektor.
Vir die doel van hierdie studie is 'n klein- tot mediumgrootte vervaardiger van lugvaartkomponente wat dien as navorsingsvennoot, bestudeer. Hulle is beskou as verteenwoordigend van die lugvaartnywerheid in Suid-Afrika vir die doel van die studie. Die navorsingsgaping is geïdentifiseer as die implementering van ʼn gehaltebeheer stelsel wat voldoen aan die AS 9100 kwaliteitsbeheer standaard. Die gevallestudie van hierdie lugvaartvervaardiger sluit die bestudering van die ontwerp, ontwikkeling en implementering van ʼn IT-gebaseerde AS 9100 gehaltestelsel in. In die studie word die navorsingsvennoot se kwaliteitstelsel en dokumente ontleed, en die stappe in die ontwerp en ontwikkeling van die nuwe stelsel verduidelik. Die implementering en die validering van die stelsel deur die outeur, word beskryf en getoets deur middel van ʼn eksterne sertifiseringsliggaam.
Hierdie studie poog om as riglyn te dien vir die fokus groep (klein- tot mediumgrootte ondernemings) en hul kennis van die AS 9100 standaard te verbreed. Hierdie kennis dra potensieel by tot die ontwikkeling van hul eie gehaltebestuur stelsels en die implementering van AS 9100 vereistes sodat akkreditasie tot die standaard verkry kan word en hul die lugvaartnywerheid kan betree. Die dokument beskryf die historiese agtergrond en huidige gebruik van die AS 9100 standaard.
Die doel van die gevallestudie is om die generiese waarde van die metode vas te stel sodat ander klein tot mediumgrootte ondernemings in staat sal wees om dieselfde metode te volg om AS 9100 te implementeer.
Die metode se geldigheid en sukses word bepaal deur middel van 'n eksterne oudit (sertifiseringsoudit) van die navorsingsvennoot in die gevallestudie. Die metode maak gebruik van 'n spesifieke IT-gebaseerde infrastruktuur om die vermindering van onnodige dokumentasie te fasiliteer. Ervarings en bevindings van ʼn soortgelyke studie in Swede, waar die outeur lid van die implementeringspan was, word ook kortliks bespreek om die geldigheid van die generiese stappe te bepaal en te beklemtoon
The Results of the Implantation of the Standard EN 9100 in Spanish Aerospace Sector
No full textA serie de normas EN 9100 constitúe unha adaptación das normas ISO 9000 ás especificidades do sector aeroespacial, para asegurar que todos os produtos relativos a este sector son seguros e competitivos. Os obxectivos deste traballo son, por un lado, analizar os resultados derivados da adhesión á normativa EN 9100 por parte das empresas do sector aeroespacial español e, por outro, verificar se eses resultados están influenciados polo tamaño desas empresas. Para iso envióuselles un cuestionario aos directores de calidade das 355 empresas que configuran este sector. Das respostas recollidas nos 115 cuestionarios recibidos, conclúese que a implantación da normativa EN 9100 ten unha influencia positiva na maioría das empresas participantes para a obtención de beneficios tanto de índole “interna” coma “externa”, sendo estes últimos os que presentan unha maior intensidade. Así mesmo, verifícase que o tamaño das empresas non provoca diferenzas significativas polo que se refire a esa influencia positiva, aínda que no tocante ás empresas “pequenas” os beneficios de tipo interno parecen obterse con maior dificultade.La serie de normas EN 9100 constituye una adaptación de las normas ISO 9000 a las especificidades del sector aeroespacial para asegurar que todos los productos relativos a este sector son seguros y competitivos. Los objetivos de este trabajo son, por un lado, analizar los resultados derivados de la adhesión a la normativa EN 9100 por parte de las empresas del sector aeroespacial español y, por otro, verificar si esos resultados están influenciados por el tamaño de esas empresas. Para ello se envió un cuestionario a los directores de calidad de las 355 empresas que configuran este sector. De las respuestas recogidas en los 115 cuestionarios recibidos, se concluye que la implantación de la normativa EN 9100 tiene una influencia positiva en la mayoría de las empresas participantes para la obtención de beneficios tanto de índole “interna” como “externa”, siendo estos últimos los que presentan una mayor intensidad. Asimismo, se verifica que el tamaño de las empresas no provoca diferencias significativas por lo que se refiere a esa influencia positiva, aunque en lo relativo a las empresas “pequeñas” los beneficios de tipo interno parecen obtenerse con mayor dificultad.The Standards series EN 9100, is an adaptation of ISO 9000 to the specific aerospace sector, to ensure that all products related to this sector, are safe and competitive. The objectives of this study are, firstly, to analyse the results from adherence to EN 9100 by the Spanish aerospace companies, and secondly, to verify if these results are influenced by the size of these companies. With this aim a questionnaire was sent to quality manager of the 355 companies that make up this sector. Of the responses collected in the 115 questionnaires received, it is concluded that the implantation of EN 9100 has a positive influence on most of the participating companies, to obtain such benefits of both “internal" and "external", the latter of which has a higher intensity. Also, it is verifies that the size of the companies does not cause significant differences in terms of this positive influence, although in regard to small firms, the benefits of internal type, seem’s to get harder
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