1,721,087 research outputs found
Effect of bone extracellular matrix synthesized in vitro on the osteoblastic differentiation of marrow stromal cells.
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48604.pdf (Publisher’s version ) (Closed access)Alternative materials for bone grafts are gaining greater importance in dentistry and orthopaedics, as the limitations of conventional methods become more apparent. We are investigating the generation of osteoinductive matrix in vitro by culturing cell/scaffold constructs for tissue engineering applications. The main strategy involves the use of a scaffold composed of titanium (Ti) fibers seeded with progenitor cells. In this study, we investigated the effect of extracellular matrix (ECM) laid down by osteoblastic cells on the differentiation of marrow stromal cells (MSCs) towards osteoblasts. Primary rat MSCs were harvested from bone marrow, cultured in dexamethasone containing medium and seeded directly onto the scaffolds. Constructs were grown in static culture for 12 days and then decellularized by rapid freeze-thaw cycling. Decellularized scaffolds were re-seeded with pre-cultured MSCs at a density of 2.5 x 10(5) cells/construct and osteogenicity was determined according to DNA, alkaline phosphatase, calcium and osteopontin analysis. DNA content was higher for cells grown on decellularized scaffolds with a maximum content of about 1.3 x 10(6) cells/construct. Calcium was deposited at a greater rate by cells grown on decellularized scaffolds than the constructs with only one seeding on day-16. The Ti/MSC constructs showed negligible calcium content by day-16, compared with 213.2 (+/- 13.6) microg/construct for the Ti/ECM/MSC constructs cultured without any osteogenic supplements after 16 days. These results indicate that bone-like ECM synthesized in vitro can enhance the osteoblastic differentiation of MSCs
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
The International Museum of Electrography (MIDE) as reflection and base of historic and artistic research in Fine Arts
No full text[ES] Bellas Artes no es sólo hablar de Educación Superior, sino de creación y experimentación en un escenario específico de investigación y contacto con el Arte. La Facultad de BBAA de Cuenca, fundada en 1985 como una propuesta educativa conectada con la cultura del Museo Abstracto, renovó la perspectiva educativa con lab-museos donde profesores-investigadores, alumnos y artistas internacionales producían obra. Uno de aquellos, el Museo Internacional de Electrografía (MIDE) creado en 1990, es un hito en la historiografía del arte y las nuevas tecnologías con más de 1800 obras creadas con la máquina electrográfica, el fax y el ordenador con una metodología creativa fundamentada en research-creation. Ofrece una visión única de las vanguardias experimentales de mitad del S.XX y principios del S.XXI, con una colección que ejemplifica el paso de lo tangible a lo intangible a través de obras de Arte Electrográfico,
Digital y Multimedia, con su difícil gestión económica y patrimonial. Debido a que esta Facultad posee otros centros similares, se ha creado CAAC (Colecciones y Archivos de Arte Contemporáneo de Cuenca) integrado por una serie de colecciones como Colección Parkett o Colección Juana Mordó, entre otras, así como una serie de archivos documentales, bibliográficos y audiovisuales como ARTEA o la productora de Pedro Almodóvar. CAAC se instaura en una metodología investigativa de calidad con aval del Ministerio de
Economía y Competitividad, tras concederle un proyecto I+D de Excelencia en su última convocatoria (12/2103,REF.:HAR2013-48604-C2-1-P) para clasificar y exponer todo a aquellos interesados en revisar la Historia de las vanguardias experimentales.[EN] Fine Arts is not only talking about Higher Education, but about creation and experimentation in a specific research scene and contact with Arts. The Faculty of Fine Arts of Cuenca, founded in 1985 as an educational proposal connected to the culture of the Abstract Museum,
renewed the educational perspective with variety lab-museums where teacher-researchers, students and international artists produced their artworks. One of these, the International Museum of Electrographic Artworks (MIDE) created in 1990, is a milestone in the historiography of art and emerging technologies with over 1800 works created with electrographic machine, fax and computer with a creative methodology based on research-creation. It provides a unique insight into the
proposals of experimental avant-garde of mid-twentieth century and the beginning of XXI century, with a collection that illustrates the passage of tangible to intangible, through works of Electrographic, Digital and Multimedia Arts, with its difficult economic and heritage
management. Since this Faculty has other similar centres, it has been created CAAC (Collections and Archives of Contemporary Art in Cuenca) composed by some collections such as Parkett Collection or Juana Mordó Collection, among others, as well as a diversity of
documentary, bibliographical and audiovisual archives as ARTEA and the production company of Pedro Almodóvar. CAAC has put in place a research quality methodology guaranteed by the Ministry of Economy and Finance, after allow a I+D Project of Excellence in its last call (12/2103,REF.:HAR2013-48604-C2-1-P) to classify and put everything available to researchers interested in reviewing the history of the experimental avant-garde
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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