1,727,428 research outputs found

    Block Card 4425 Dorr Street

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    This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Ranch houses | 4425 Dorr Street (Toledo, Ohio) | Dwelling | Reynolds Corners Area (Toledo, Ohio

    Block Card 4425 Hill Avenue

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    This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Small Animal Medical Center (Toledo, Ohio) | Postmodern Style | 4425 Hill Avenue (Toledo, Ohio) | commercial buildings | Adams Township Area (Toledo, Ohio

    Block Card 4425 Holly Hill Drive

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    This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: 4425 Holly Hill Drive (Toledo, Ohio) | Glen Ellyn Park (Toledo, Ohio) | South Toledo Area (Toledo, Ohio) | Cape Cod Style | Dwellin

    L'iscrizione CIL V, 4425. Un'iscrizione di Brixia perduta e ritrovata

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    The Roman inscription CIL V, 4425 was ranked among the deperditae of Brixia; disappearance perhaps as early as the sixteenth century, has recently resurfaced in fragmentary Fornaci at Bresci

    Ginsenoside Rh2 upregulates long noncoding RNA STXBP5-AS1 to sponge microRNA-4425 in suppressing breast cancer cell proliferation

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    Background: Ginsenoside Rh2, a major saponin derivative in ginseng extract, is recognized for its anticancer activities. Compared to coding genes, studies on long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) that are regulated by Rh2 in cancer cells, especially on competitive endogenous RNA (ceRNA) are sparse. Methods: LncRNAs whose promoter DNA methylation level was significantly altered by Rh2 were screened from methylation array data. The effect of STXBP5-AS1, miR-4425, and RNF217 on the proliferation and apoptosis of MCF-7 breast cancer cells was monitored in the presence of Rh2 after deregulating the corresponding gene. The ceRNA relationship between STXBP5-AS1 and miR-4425 was examined by measuring the luciferase activity of a recombinant luciferase/STXBP5-AS1 plasmid construct in the presence of mimic miR-4425. Results: Inhibition of STXBP5-AS1 decreased apoptosis but stimulated growth of the MCF-7 cells, suggesting tumor-suppressive activity of the lncRNA. MiR-4425 was identified to have a binding site on STXBP5-AS1 and proven to be downregulated by STXBP5-AS1 as well as by Rh2. In contrast to STXBP5-AS1, miR-4425 showed pro-proliferation activity by inducing a decrease in apoptosis but increased growth of the MCF-7 cells. MiR-4425 decreased luciferase activity from the luciferase/STXBP5-AS1 construct by 26%. Screening the target genes of miR-4425 and Rh2 revealed that Rh2, STXBP5-AS1, and miR-4425 consistently regulated tumor suppressor RNF217 at both the RNA and protein level. Conclusion: LncRNA STXBP5-AS1 is upregulated by Rh2 via promoter hypomethylation and acts as a ceRNA, sponging the oncogenic miR-4425. Therefore, Rh2 controls the STXBP5-AS1/miR-4425/RNF217 axis to suppress breast cancer cell growth

    55/01/20 State Bills Sam $4425 for Trial

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    Dr. Sam will be billed $4425 for the court costs of his conviction. State law provides that anyone convicted of a felony can be compelled to pay them, if they are financially able to do so.https://engagedscholarship.csuohio.edu/newspaper_coverage/1649/thumbnail.jp

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Linked collectors and determiners for: Florida State Collection of Arthropods.

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    Natural history specimen data linked to collectors and determiners held within, "Florida State Collection of Arthropods". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="http://bionomia.net/dataset/86760641-4425-4130-9d20-4dd1eaa5c4a4">https://bionomia.net/dataset/86760641-4425-4130-9d20-4dd1eaa5c4a4</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/86760641-4425-4130-9d20-4dd1eaa5c4a4">https://gbif.org/dataset/86760641-4425-4130-9d20-4dd1eaa5c4a4</a>. Formatted as a Frictionless Data package

    Linked collectors and determiners for: Biomasa y rasgos foliares de Cucurbita ficifolia y Rubus bogotensis en un área bajo restauración ecológica en Bogotá, D.C..

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    Natural history specimen data linked to collectors and determiners held within, "Biomasa y rasgos foliares de Cucurbita ficifolia y Rubus bogotensis en un área bajo restauración ecológica en Bogotá, D.C.". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="http://bionomia.net/dataset/b674da50-c505-4425-8e59-e0e6906f2be9">https://bionomia.net/dataset/b674da50-c505-4425-8e59-e0e6906f2be9</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/b674da50-c505-4425-8e59-e0e6906f2be9">https://gbif.org/dataset/b674da50-c505-4425-8e59-e0e6906f2be9</a>. Formatted as a Frictionless Data package
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