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Other title: House Bill 2307 Advisory Committee Report
No full textapplication/pdf; "Approved 12/2/05.""House Judiciary Chair Michael R. O'Neal requested that the Judicial Council study 2005 House Bill No. 2307 relating to the appointment of guardians and conservators. The Judicial Council agreed to undertake the study of HB 2307 and formed a new advisory committee to study the proposed amendment to K.S.A. 2004 Supp. 59-3075, which relates to the guardian's authority to consent to the withholding or withdrawing of life-saving or life sustaining medical care, treatment, services or procedures from a ward."
ICS 2307 SIMULATION AND MOCELLING [supplementary] (1)
No full textICS 2307 SIMULATION AND MOCELLING [supplementary] (1
Other title: 2005 House Bill 2307; Other title: 2005 HB 2307
No full textapplication/pdf; "Approved by the Judicial Council December 2, 2005.""House Judiciary Chair Michael R. O'Neal requested that the Judicial Council study 2005 House Bill No. 2307 relating to the appointment of guardians and conservators. HB 2307 proposes to amend K.S.A. 2004 Supp. 59-3068, which currently relates to the priority of nominees and their qualifications when a guardian is appointed and K.S.A. 2004 Supp. 59-3075, which currently relates to a guardian's duties, responsibilities, powers and authority."
The Novel Arylamidine T-2307 Selectively Disrupts Yeast Mitochondrial Function by Inhibiting Respiratory Chain Complexes
Get PDFNagasaki University (長崎大学)博士(医学)The novel arylamidine T-2307 exhibits broad-spectrum in vitro and in vivo antifungal activities against clinically significant pathogens. Previous studies have shown that T-2307 accumulates in yeast cells via a specific polyamine transporter and disrupts yeast mitochondrial membrane potential. Further, it has little effect on rat liver mitochondrial function. The mechanism by which T-2307 disrupts yeast mitochondrial function is poorly understood, and its elucidation may provide important information for developing novel antifungal agents. This study aimed to determine how T-2307 promotes yeast mitochondrial dysfunction and to investigate the selectivity of this mechanism between fungi and mammals. T-2307 inhibited the respiration of yeast whole cells and isolated yeast mitochondria in a dose-dependent manner. The similarity of the effects of T-2307 and respiratory chain inhibitors on mitochondrial respiration prompted us to investigate the effect of T-2307 on mitochondrial respiratory chain complexes. T-2307 particularly inhibited respiratory chain complexes III and IV not only in Saccharomyces cerevisiae but also in Candida albicans, indicating that T-2307 acts against pathogenic fungi in a manner similar to that of yeast. Conversely, T-2307 showed little effect on bovine respiratory chain complexes. Additionally, we demonstrated that the inhibition of respiratory chain complexes by T-2307 resulted in a decrease in the intracellular ATP levels in yeast cells. These results indicate that inhibition of respiratory chain complexes III and IV is a key factor for selective disruption of yeast mitochondrial function and antifungal activity.長崎大学学位論文 学位記番号:博(医歯薬)乙第59号 学位授与年月日:令和2年9月2日Author: Kohei Yamashita, Taiga Miyazaki, Yoshiko Fukuda, Junichi Mitsuyama, Tomomi Saijo, Shintaro Shimamura, Kazuko Yamamoto, Yoshifumi Imamura, Koichi Izumikawa, Katsunori Yanagihara, Shigeru Kohno, Hiroshi MukaeCitation: Antimicrobial Agents and Chemotherapy, 63(8), e00374-19; 2019Nagasaki University (長崎大学), 博士(医学) (2020-09-02)doctoral thesi
Block Card 2307 Byrneway Avenue
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: 2307 Byrneway Avenue (Toledo, Ohio) | duplexes | Byrne Way Subdivision (Toledo, Ohio) | South Toledo Area (Toledo, Ohio) | Modern Colonial Styl
Block Card 2307 Lawrence Avenue
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Gabled Ell | 2307 Lawrence Avenue (Toledo, Ohio) | Dwelling | Hollywood Addition (Toledo, Ohio) | Auburndale Area (Toledo, Ohio
Block Card 2307 Ashland Avenue
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Queen Anne | Dwelling | Toledo Olde Towne (Toledo, Ohio) | B.T. Scotts First Addition | Lee and Browns Division | Ashland Place Addition (Toledo, Ohio) | Tremain Drive | 2307 Ashland Avenue (Toledo, Ohio) | Collingwood Boulevard (Toledo, Ohio
Block Card 2307 Belvedere Drive
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: 2307 Belvedere Drive (Toledo, Ohio) | Heatherwoods (Toledo, Ohio) | South Toledo Area (Toledo, Ohio) | Ranch houses | Dwellin
Block Card 2307 Cardinal Street
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: False front | 2307 Cardinal Street (Toledo, Ohio) | apartment building | multi-family | W.P. Anderson and Company Addition | Auburndale Area (Toledo, Ohio
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