3,961,363 research outputs found
Campus Author 2016 Event Program
No full textCampus Author 2016 celebrated the 11th year of the Campus Author Recognition Program. The 2016 event celebrated 90 authors and 101 books. This is the event program for the 2016 Campus Author Recognition Program annual reception held Thursday March 9, 2017 in the Atrium of the Summerlee Science Complex, University of Guelph
Target product profile for a diagnostic assay to differentiate between bacterial and non-bacterial infections and reduce antimicrobial overuse in resource-limited settings: an expert consensus
No full textAcute fever is one of the most common presenting symptoms globally. In order to reduce the empiric use of antimicrobial drugs and improve outcomes, it is essential to improve diagnostic capabilities. In the absence of microbiology facilities in low-income settings, an assay to distinguish bacterial from non-bacterial causes would be a critical first step. To ensure that patient and market needs are met, the requirements of such a test should be specified in a target product profile (TPP). To identify minimal/optimal characteristics for a bacterial vs. non-bacterial fever test, experts from academia and international organizations with expertise in infectious diseases, diagnostic test development, laboratory medicine, global health, and health economics were convened. Proposed TPPs were reviewed by this working group, and consensus characteristics were defined. The working group defined non-severely ill, non-malaria infected children as the target population for the desired assay. To provide access to the most patients, the test should be deployable to community health centers and informal health settings, and staff should require 90% and >80% for sensitivity and specificity, respectively. Other key characteristics, to account for the challenging environment at which the test is targeted, included: i) time-to-result <10 min (but maximally <2 hrs); ii) storage conditions at 0-40°C, ≤90% non-condensing humidity with a minimal shelf life of 12 months; iii) operational conditions of 5-40°C, ≤90% non-condensing humidity; and iv) minimal sample collection needs (50-100μL, capillary blood). This expert approach to define assay requirements for a bacterial vs. non-bacterial assay should guide product development, and enable targeted and timely efforts by industry partners and academic institutions
Alumni Author 2016
No full textAlumni author Nicky P.E. Tomboulides shared her book, It Is a Green Clean World: The World Travels of Takis and Mimi, Ryan Matura Library September 17, 2016.https://digitalcommons.sacredheart.edu/libraryhistoryphotos/1085/thumbnail.jp
Doubting John?
No full textThis essay focuses on the figure of John the Baptist in prison and the question he sent his disciples to ask Christ: was he ‘the one who is to come’ (Matthew 11: 2–3). Having observed how the Fathers strove to distance John from the perils of doubt in their readings of this passage, it traces the way their arguments were picked up by twelfth and thirteenth-century biblical exegetes and then by authors of anti-heretical dispute texts in urban Italy, where the Baptist was a popular patron saint. So as to give force to their own counter-arguments, learned polemicists, clerical and lay, made much of heretics’ hostility to John, powerfully ventriloquizing a doubting, sceptical standpoint. One counter-argument was to assign any doubts to John’s disciples, for whose benefit he therefore sent to ask for confirmation of the means of Christ’s return, neatly moving doubt from questions of faith to epistemology. Such ideas may have seeped beyond the bounds of a university trained elite, as is perhaps visible in a fourteenth-century fresco representing John in prison engaging with anxious disciples. But place, audience and genre determined where doubt was energetically debated and where it was more usually avoided, as in sermons for the laity on the feast of a popular saint
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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