1,735,236 research outputs found
С 1263-1613
Get PDFШишонко, Василий Никифирович (1833-1889). Пермская летопись с 1263-1881 [5 пер.] / Сост. чл. разных учен. о-в, дир. нар. уч-щ Пермс. губ. Василий Шишонко; Изд. печ. на средства Губ. земства. - Пермь : Тип. Губ. зем. управы. - 1881 Период 1 : С 1263-1613. - 1881. - [2], II, 238 с. ; 26 см Экземпляры: всего:1 - ВЖК(1
Santa Fe (ATSF) 1263
No full textA photograph print showing Santa Fe (ATSF) 1263, 4-6-2, Riverbank, CA
Il condrosarcoma periferico orale primitivo: aspetti anatomo-clinici e presentazione di due casi ad insorgenza parodontale.
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Abstract 1263: Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90
No full textAbstract
Most cancers are characterized by multiple molecular alterations, but identification of the key proteins involved in these signaling pathways is currently beyond reach. We show that the inhibitor PU-H71 preferentially targets tumor-enriched Hsp90 complexes and affinity captures Hsp90-dependent oncogenic client proteins. We have used PU-H71 affinity capture to design a proteomic approach that, when combined with bioinformatic pathway analysis, identifies dysregulated signaling networks and key oncoproteins in chronic myeloid leukemia. The identified interactome overlaps with the well-characterized altered proteome in this cancer, indicating that this method can provide global insights into the biology of individual tumors, including primary patient specimens. In addition, we show that this approach can be used to identify previously uncharacterized oncoproteins and mechanisms, potentially leading to new targeted therapies.
Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2012;72(8 Suppl):Abstract nr 1263. doi:1538-7445.AM2012-126
Les habitants d'Orly en 1263
No full textMaillard François. Les habitants d'Orly en 1263. In: Bulletin de la Société Nationale des Antiquaires de France, 1985, 1987. pp. 179-188
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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