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Spatiotemporal variations in the levels of toxic elements in drinking water of Sivas, Türkiye, and an ecotoxicological risk assessment
No full textThis study was conducted in 2022 to investigate the water variables of fountains used by people for drinking purposes in Şarkışla (Sivas, Türkiye). Five stations were selected from the most frequently used fountains. Sampling was carried out seasonally. Various physicochemical variables such as water temperature (WT), pH, electirical conductivity (EC), dissolved oxygen (DO), nitrite (NO2), nitrate (NO3), phosphate (PO4), sulphate (SO4), magnesium (Mg), calcium (Ca), total hardness (TH), chloride (Cl), salinity, total dissolved solids (TDS), arsenic (As), cadmium (Cd), zinc (Zn), manganese (Mn), and copper (Cu) were investigated. Additionally, the Nitrate Pollution Index (NPI), Groundwater Quality Index (GWQI), and Human Health Risk Assesment (HHRA) methods were applied to the data. One of the main objectives of this study was to conduct health risk assessments for people using water from drinking fountains and to identify both carcinogenic and non-carcinogenic metals. As a result of this research, NPI values indicated slight contamination, while no contamination was found based on GWQI values. The Mn and Cd were found to slightly exceed the permissible limit values. As, which exceeds the limit value in water, was found to pose a serious carcinogenic risk (CR) for both children and adults. High As values are from quaternary alluvial deposits and aquifer layers of Pliocene terrestrial layers. Considering the hazard quotient (HQ) and hazard index (HI) for the presence of Cd, it was determined that it poses a serious risk to humans and children through both ingestive and dermal exposure. At the end of the study, several recommendations for the sustainable use of drinking fountains water were provided. © The Author(s) 2025.Sivas Cumhuriyet Üniversites
Analyse du processus de planification stratégique du tourisme de santé en turquie
No full textBu çalışmanın amacı Türkiye'nin sağlık turizmi alanındaki mevcut durumunu, sağlık turizminin kurumsal örgütlenme sürecini, yasal düzenlemeleri ve uygulanan politikaları bütüncül bir şekilde analiz etmektir. Çalışmada metin/doküman analizi tekniği kullanılmış; bu çerçevede konuyla ilgili birincil ve ikincil kaynaklar üzerinden değerlendirmeler yapılmıştır. Bu çalışmanın amaca ulaşması için kurumsal örgütlenme süreci, kalkınma planları, bölge planları, yasal düzenlemeler birincil kaynaklardan incelenmiştir. Yapılan analiz sonucunda; Türkiye'de sağlık turizmi alanında gerçekleştirilen çalışmaların son yirmi yılda yoğunlaştığı görülmektedir. Kurumsal örgütlenmeye yönelik atılan adımlar, yasal düzenlemeler, kalkınma ve bölge planlarında sağlık turizmine yönelik strateji ve hedefler belirlendiği ve bu doğrultuda politikalar üretildiği gözlenmektedir. Türkiye sağlık turizminde potansiyeli bulunan bir ülkedir. Bu alanda önde gelen ülkelerle rekabet edecek bir kapasitesinin bulunduğu ancak hedeflenen seviyeye ulaşılamadığı tespit edilmiştir. Sağlık turizmindeki mevcut durumun iyileştirilmesi, özellikle zengin termal kaynakların termal turizm için kullanılması, etkili tanıtım ve pazarlama stratejilerinin geliştirilmesi ile Türkiye'nin sağlık turizminde hedef destinasyon olacağı ve sağlık turizminin ekonomik büyümede etkili bir sektör haline geleceği öngörülmektedir.The aim of this study is to analyze Turkey's current situation in the field of health tourism, the institutional organization process of health tourism, legal regulations and policies implemented in a holistic manner. In the study, text/document analysis technique was used and evaluations were made through primary and secondary sources on the subject. In order to achieve the aim of this study, the institutional organization process, development plans, regional plans and legal regulations were examined from primary sources. As a result of the analysis, it is seen that the studies on health tourism in Turkey have intensified in the last two decades. It is observed that the steps taken towards institutional organization, legal regulations, development and regional plans have set strategies and targets for health tourism and policies have been produced in this direction. Turkey is a country with potential in health tourism. It has the capacity to compete with leading countries in this field, but the targeted level has not been reached. With the improvement of the current situation in health tourism, especially the utilization of rich thermal resources for thermal tourism, and the development of effective promotion and marketing strategies, it is predicted that Turkey will become a target destination in health tourism and health tourism will become an effective sector in economic growth
A Research on the Associations of Brand Reputation
No full textBu çalışma, marka itibarı kavramını ve tüketici algıları üzerindeki çağrışımlarını incelemeyi amaçlamaktadır. Marka itibarı, tüketici zihninde markanın sunduğu kalite, güvenilirlik ve değer gibi unsurların yanı sıra, duygusal bağlar ve toplumsal duyarlılık algılarıyla şekillenir. Marka itibarı çağrışımları; duygusal bağlar, değer, iletişim, performans, toplumsal duyarlılık, vizyon, güç ve karizma eksenli olarak sekiz temel kategoride ele alınmıştır. Bu kategoriler, markanın tüketici zihninde hangi yönleriyle ön plana çıktığını anlamak için daha önce literatürde olmayan sistematik bir çerçeve sunmaktadır. Araştırmada, markanın yalnızca rasyonel unsurlarla değil, aynı zamanda duygu, değer temelli ve etik bağlamlarla da güçlü bir konum yaratması gerektiği vurgulanmaktadır. Çalışma marka, marka çağrımı ve itibar kavramlarının detaylı olarak incelenmesi sonucu mevcut olan bu kavramlarla da desteklenerek ortaya çıkarılan yeni bir kavram olan marka itibarı çağrışımlarının, türlerini, kategorilerini, niteliğe dayalı itibar çağrışımlarını ve marka itibarı çağrışım rezonansını içermektedir. Literatüre bu çerçevede gerek teorik gerekse uygulamalı çalışmalar için farklı bir bakış açısı ile katkı sunmaktadır. Bu bağlamda marka itibarı çağrışımları farklı boyutlardan ele alınmıştır. Çalışma bu boyutlarıyla akademik olarak halkla ilişkiler, marka iletişimi, pazarlama ve uygulamalı halkla ilişkiler literatürüne katkıda bulunmayı hedeflemektedir.This study aims to examine the concept of brand reputation and its connotations on consumer perceptions. Brand reputation is shaped by elements such as quality, reliability and value offered by the brand in the minds of consumers, as well as emotional ties and perceptions of social sensitivity. Brand reputation associations are analysed in eight basic categories based on emotional ties, value, communication, performance, social sensitivity, vision, power and charisma. These categories provide a systematic framework to understand which aspects of the brand stand out in the minds of consumers, which was not previously available in the literature. The study emphasises that a brand should create a strong position not only through rational elements but also through emotional, value-based and ethical contexts. The study includes the types, categories, attribute-based reputation associations and brand reputation association resonance, which is a new concept emerged as a result of a detailed examination of the concepts of brand, brand association and reputation, supported by these existing concepts. In this framework, it contributes to the literature with a different perspective for both theoretical and applied studies. In this context, brand reputation connotations are discussed from different dimensions. With these dimensions, the study aims to contribute to the academic literature on public relations, brand communication, marketing and applied public relations
Efficient TF-IDF method for alignment-free DNA sequence similarity analysis
No full textThis study proposes a pioneering alignment-free approach for the analysis of DNA sequence similarity. The method employs the representation of DNA sequences as n-grams, a technique that involves the adaptation of the Term Frequency-Inverse Document Frequency (TF-IDF) algorithm to genomic data. The primary objective of this approach is to enhance the accuracy of the results while concomitantly reducing the computational costs of the process, by ascertaining the most informative n-grams. The approach adopted in this study successfully circumvents the limitations of both traditional alignment-based and alignment-free methods, thereby demonstrating a commendable level of performance. The proposed method was tested on three different datasets and achieved high agreement with reference phylogenetic trees in the AFProject benchmark system. The results demonstrate that TF-IDF-based similarity matrices effectively capture phylogenetic relationships and significantly reduce processing time. The high accuracy rates obtained prove that the method offers a scalable and robust alternative in large genomic datasets. The method demonstrates considerable potential in DNA sequence similarity analysis, exhibiting high accuracy and low computational cost
Exploring nonlinear optical properties of single δ-doped quantum wells: influences of position-dependent mass, temperature, and hydrostatic pressure
No full textThis study investigates the multifaceted impact of position-dependent effective mass, temperature, and hydrostatic pressure on the electronic and optical properties of single-doped quantum wells, with a particular emphasis on varying doping levels. Utilizing effective mass and parabolic band approximations, calculations were meticulously conducted via the diagonalization method, employing a trigonometric orthonormal function basis to elucidate the eigenvalues and eigenfunctions of the confined electron potential. The obtained results unveil substantial alterations in electron energies, state transitions, and absorption spectra consequent to fluctuations in doping levels, temperature, and pressure. These findings provide profound insights into the intricate interplay between semiconductor characteristics and external stimuli, laying a foundation for the optimization of laser and optoelectronic devices through the tailored engineering of material properties. This comprehensive understanding not only advances fundamental knowledge in semiconductor physics but also paves the way for the development of innovative materials with customized optical functionalities, thus driving progress in a wide array of technological applications.Scientific and Technological Research Council of Turkiye (TUBITAK)Open access funding provided by the Scientific and Technological Research Council of Turkiye (TUBITAK)
Group Counseling Education Program for Parents of Children With Autism Spectrum Disorder Effect on Parents' Psychological Resilience, Life Satisfaction, and Family Functioning
No full textPURPOSE: To investigate the effects of a group counseling education program (GCEP) provided to parents of children with autism spectrum disorder (ASD) on parents'psychological resilience, life satisfaction, and family functioning. METHOD: This experimental study was conducted with 30 parents of children with ASD. Data were collected using a Personal Information Form, the Adult Psychological Resilience Scale, Satisfaction With Life Scale, and Family Assessment Device. The GCEP, comprising 10 sessions, was provided to the intervention group once per week. RESULTS: The GCEP significantly increased psychological resilience levels in the intervention group compared to the control group. Although there were no significant differences between groups regarding Family Assessment Device subscale scores before the GCEP, after the program, mean scores on the subscales of problem solving, communication, roles, and behavioral control of the intervention group were significantly lower than those of the control group. No significant differences were observed in life satisfaction between groups. CONCLUSION: The GCEP was effective in improving psychological resilience and family functioning. Family counseling programs for raising awareness and provision of psychosocial support may be developed and applicable in relation to infamily relationships, care and responsibilities for the child, and problem solving for parents of children with ASD. [Journal of Psychosocial Nursing and Mental Health Services, xx(xx), xx-xx.
Effect of modeling liquid application on color stability and surface roughness of single-shade composites
No full textObjectives The objective of this study was to examine the effects of modeling liquid application on the color stability and surface roughness of single-shade composites. Materials and methodsSingle-shade composites were divided into 4 main groups according to their contents. A total of 64 disc-shaped samples (8 x 2 mm) were prepared, 16 in each group, by using Teflon molds. The samples were divided into two subgroups on the basis of the application of a modeling liquid. After the initial color and roughness measurements, the samples were immersed in coffee for 12 days. Color changes were assessed via a spectrophotometer and Delta E values were calculated via the CIELAB formula. The surface roughness (Ra) was measured via a profilometer. The data were subjected to statistical analysis via two-way analysis of variance and Tukey's test to examine pairwise differences at a significance level of 0.05. Results The application of modeling liquid reduced discoloration in Charisma Diamond One (CDO) and Vittra APS Unique (VUA), whereas it slightly increased discoloration in Omnichroma (OMN) and Zenchroma (ZNC). However, only the changes in CDO were statistically significant (p 0.05). The surface roughness and color changes approached the mean values in the subgroups where the modeling liquid was applied, and there was no significant difference between them (p > 0.05). The application of modeling liquid was observed to reduce the variation in initial roughness among the composites, bringing their roughness values closer to an average range (0.26-0.34). Conclusion Modeling liquid application increased roughness and discoloration in composites with initially low surface roughness (OMN and ZNC) while reducing roughness and discoloration in composites with initially high surface roughness (VUA and CDO). Clinical relevance Modeling liquid application should be approached more cautiously in composites with high polishability, despite contributing to clinical use in composites with high roughness values
İKİNCİ BRANKİYAL YARIK KİSTİ ÖN TANILI HASTALARDA HİSTOPATOLOJİK DOĞRULUK PAYI VE AYIRICI TANISINDA SERVİKAL TÜBERKÜLOZUN ÖNEMİ Histopathological Accuracy in Patients Prediagnosed with Second Branchial Cleft Cyst and the Importance of Cervical Tuberculosis in Differential Diagnosis
No full textAmaç: Bu çalışmanın amacı, fizik muayene ve görüntüleme yöntemleri ile Brankial Yarık Kisti (BYK) ön tanısı konulan hastaların, cerrahi öncesi ince iğne aspirasyon biyopsi (İİAB) verisi olmadan cerrahi sonrası histopatolojik sonuçların da doğruluk payını araştırmak ve ayırıcı tanılar arsında yer alan servikal tüberkülozun önemini tartışmaktır. Gereç ve Yöntemler: Bir üçüncü basamak Üniversite Hastanesi Kulak Burun Boğaz kliniğinde 2009-2020 yılları arasında boyunda kitle şikayeti ile başvuran ve ön tanısı BYK olan hastaların operasyon sonrası histopatolojik verilerin analizi yapılarak sonuçlar değerlendirildi. Operasyon öncesi İİAB verisi olmayan hastalar çalışmaya dahil edildi. Histopatolojik sonuçları ile ön tanı uyumlu hastalar Grup 1, ön tanı ile uyumlu olmayan hastalar Grup 2 olarak sınıflandırıldı. Retrospektif elde edilen veriler parametrik olmayan testler ile SPSS paket programında analiz edilmiştir. Bulgular: BYK tanısı ile ameliyat edilen 22 erkek, 22 kadın toplam 44 hasta çalışmaya dahil edildi. Toplam 24 hastanın histopatolojik sonucu BYK ile uyumlu idi. Grup 1 olarak değerlendirilen 24 hastanın yaş ortalaması 23 olarak hesaplandı. Hastalar toplam olarak cinsiyetler açısından karşılaştırıldığında anlamlı farklılık izlenmedi (p>0,05). Grup 2’de histopatoloji sonucu tüberküloz olan hastaların yaş ortalaması 58 idi. Gruplar arası istatistiksel olarak anlamlı fark tespit edildi (p=0,020). Sonuç: Boyun kitleleri ile başvuran hastalarda BYK ön tanısının doğrulanması, multidisipliner bir yaklaşım gerektirir. Klinik, radyolojik ve histopatolojik bulguların bir arada değerlendirilmesi, doğru tanı ve tedavi stratejisinin belirlenmesinde hayati önem taşımaktadır. Özellikle ileri yaş hastalarda, tüberküloz gibi enfeksiyöz patolojilerin de dikkate alınması, tanısal gecikmelerin önlenmesine ve tedavinin doğru yönlendirilmesine yardımcı olacaktır.Amaç: Bu çalışmanın amacı, fizik muayene ve görüntüleme yöntemleri ile Brankial Yarık Kisti (BYK) ön tanısı konulan hastaların, cerrahi öncesi ince iğne aspirasyon biyopsi (İİAB) verisi olmadan cerrahi sonrası histopatolojik sonuçların da doğruluk payını araştırmak ve ayırıcı tanılar arsında yer alan servikal tüberkülozun önemini tartışmaktır. Gereç ve Yöntemler: Bir üçüncü basamak Üniversite Hastanesi Kulak Burun Boğaz kliniğinde 2009-2020 yılları arasında boyunda kitle şikayeti ile başvuran ve ön tanısı BYK olan hastaların operasyon sonrası histopatolojik verilerin analizi yapılarak sonuçlar değerlendirildi. Operasyon öncesi İİAB verisi olmayan hastalar çalışmaya dahil edildi. Histopatolojik sonuçları ile ön tanı uyumlu hastalar Grup 1, ön tanı ile uyumlu olmayan hastalar Grup 2 olarak sınıflandırıldı. Retrospektif elde edilen veriler parametrik olmayan testler ile SPSS paket programında analiz edilmiştir. Bulgular: BYK tanısı ile ameliyat edilen 22 erkek, 22 kadın toplam 44 hasta çalışmaya dahil edildi. Toplam 24 hastanın histopatolojik sonucu BYK ile uyumlu idi. Grup 1 olarak değerlendirilen 24 hastanın yaş ortalaması 23 olarak hesaplandı. Hastalar toplam olarak cinsiyetler açısından karşılaştırıldığında anlamlı farklılık izlenmedi (p>0,05). Grup 2’de histopatoloji sonucu tüberküloz olan hastaların yaş ortalaması 58 idi. Gruplar arası istatistiksel olarak anlamlı fark tespit edildi (p=0,020). Sonuç: Boyun kitleleri ile başvuran hastalarda BYK ön tanısının doğrulanması, multidisipliner bir yaklaşım gerektirir. Klinik, radyolojik ve histopatolojik bulguların bir arada değerlendirilmesi, doğru tanı ve tedavi stratejisinin belirlenmesinde hayati önem taşımaktadır. Özellikle ileri yaş hastalarda, tüberküloz gibi enfeksiyöz patolojilerin de dikkate alınması, tanısal gecikmelerin önlenmesine ve tedavinin doğru yönlendirilmesine yardımcı olacaktır
Influence of gender on Behcet's disease phenotype and irreversible organ damage: Data from the International AIDA Network Behcet's Disease Registry
No full textObjectives. - Gender impact on phenotypical expression of Behcet's disease (BD) has been specifically investigated only in a few large-scale studies. The main goal of the study was to examine gender differences in a large cohort of patients affected by BD. Methods. - Data were retrieved from the International AIDA Network Registry for BD. We assessed differences between males and females in terms of Behcet's syndrome Overall Damage Index (BODI), differences in the disease manifestations at onset and in the cumulative manifestations throughout diseasecourse, as well as differences in the cardiovascular risk. Finally, predictive factors leading to major organ involvement were investigated. Results. - In total, 1024 BD patients (567 males, 457 females) were enrolled in the study, with a male-to-female ratio of 1.24/1. Males displayed a significantly higher mean +/- SD BODI (1.92 +/- 2.09) at the last follow-up, compared to female patients (1.25 +/- 1.87) (P < 0.0001). Uveitis (P < 0.0001) and vascular involvement (P = 0.0076) were significantly more frequent among males whereas female patients were significantly over-represented in arthralgia (P < 0.0001), arthritis (P = 0.00025), isolated headache (P < 0.0001), central nervous system (CNS) involvement (P = 0.040), and gastrointestinal involvement (P = 0.00046). Regarding cardiovascular risk, no differences between the two groups emerged (P = 0.617). Four variables were associated with the development of major organ involvement: male gender (OR = 2.104, P = 0.001), current treatment with biologic agents (OR = 2.257, P = 0.0003), origin from endemic countries (OR = 2.661, P = 0.0009), and disease duration (OR = 1.002, P = 0.024). Conclusion. - BD displays a more severe course among males. This subgroup develops more irreversible damage and presents more frequently ocular and vascular involvement during disease course. On the other hand, female patients are prone to experience articular involvement, headache, CNS and gastrointestinal involvement. These data suggest the existence of a gender-driven disease expression. (c) 2024 Les Auteurs. Publie par Elsevier Masson SAS au nom de Socioto Franoaise de Rhumatologie. Cet article est publie en Open Access sous licence CC BY (http://creativecommons.org/licenses/by/4.0/).S.I.M.B.A (Associazione Italiana Sindrome e Malattia di Behcet)This study received funding from the patient advocacy organization S.I.M.B.A (Associazione Italiana Sindrome e Malattia di Behcet)