Sivas Cumhuriyet Üniversitesi Kurumsal Akademik Arşivi - Sivas Cumhuriyet University Open Access System
Not a member yet
34175 research outputs found
Sort by
Quantum chemical study of thiaozole derivatives as corrosion inhibitors based on density functional theory
No full textQuantum chemical and theoretical calculations were carried out in the present study of
some thiaozole derivatives. Relationship between electronic parameters of thiaozole derivatives 5-
benzylidene-2,4-dioxo tetrahydro1,3-thiazole (5-BDT) 5-(40-isopropylbenzylidene)-2,4-dioxotetrahy
dro-1,3-thiazole (5IPBDT), 5-(30-thenylidene)-2,4-dioxotetrahydro-1,3-thiazole (5-TDT) and 5-(30,
40dimetoxybenzylidene)-2,4-dioxotetrahydro-1,3-thiazole (5-MBDT) and corrosion inhibition efficiency
have been investigated by the Hartree-Fock (HF) and Becke, 3-parameter, Lee-Yang-Parr
(B3LYP), M06-2X method with 3-21G, 6-31G, and sdd basis set. All calculations have been performed
using the Gaussian 09W suite of programs. The properties most relevant to their potential
action as corrosion inhibitors: EHOMO, ELUMO, DE (HOMO-LUMO energy gap), electronegativity
(v), chemical potential (l), chemical hardness (g), electrophilicity (x), nucleophilicity (e), global
softness (r) and proton affinity (PA) have been studied
Sexual experiences and quality of life in Turkish women using methods of contraception
No full textThe aim of this study was to examine the sexual experiences and quality of life in women using methods of contraception. The sample of this descriptive study consisted of 259 women. The data were collected by the Personal Information Form, the Arizona Sexual Experiences Scale (ASES) and the World Health Organisation Quality of Life Scale (WHOQOL-BREF). It was found that 35.1% of the women use condoms, 30.1% of them use the Intrauterine Device (IUD), 22.0% had problems using the method and 39% had the side effects while using the method. There was a statistically significant difference between the state of having problems using the methods and quality of life average scores and between the state of having side effects and sexual life and quality of life average scores (p < .05).Impact statement What is already known on this subject? Sexual problems are common health problems among women and can lead to loss of self-esteem in women, depression and emotional stress. What do the results of this study add? Women who experience problems using a contraception method have a lower quality of life. Sexual dysfunctions were higher among those who experienced side effects of the methods, quality of life scores were lower
Trace analysis of quercetin in tea samples by HPLC-DAD system by means of a new nanocomposite including magnetic core-shell
No full textA new magnetic core-shell multiwalled carbon nanotube@nanodiamond nanocomposite was synthesized, characterized and used as magnetic solid-phase extraction material. The usability of material was checked on the separation and pre-concentration of quercetin in tea samples by magnetic solid-phase extraction and high-performance liquid chromatography with diode array detector system. There was a linear relationship between chromatographic area and concentration of quercetin in the range of 5.0-600 ng mL(-1). The limit of detection and quantification limits were 1.46 and 4.91 ng mL(-1), respectively. The developed method has been applied to determine quercetin at trace levels in tea samples
Immunohistochemical profile of CD markers in experimental neural tube defect
No full textNeural tube defects (NTDs) are the second most common birth defects worldwide. Stem cells play a critical role in the mechanisms underlying NTDs. We established an experimental NTD model in rats using retinoic acid (RA). We used mesenchymal and hemopoietic stem cell markers to determine their distribution in the mesenchyme in and around the neuroepithelium during the embryonic and fetal periods in both cranial and caudal regions. Adult female rats were given RA on days 5 and 10 of gestation and olive oil was administered to the control group. On days 10.5 and 15.5, embryos in the experimental and control groups were removed from the uterus. Embryos were embedded in paraffin and serial sections of the cranial and caudal neural tube were examined. We found severe cranial and caudal defects including axial rotation in the experimental groups using histochemistry. We used CD44, CD56, CD73, CD90, CD105, CD271 antibodies as mesenchymal stem cell markers and CD14, CD45 as hemopoietic stem cell markers. More CD44, CD56, CD90, CD105 and CD14 were detected during the embryonic period than the fetal period. CD73 was more frequent during the fetal period, whereas CD271 and CD45 were not significantly different. When CD44, CD56, CD73, CD90, CD105, CD271 immunostaining was found, NTDs were decreased early and increased later. We found no significant difference between CD14 and CD45. Formation of NTDs was due to deterioration of the of the neuroepithelial and surrounding stem cells. One reason for the formation of NTDs is that stem cells may develop defective cell-cell or cell-matrix interactions.Cumhuriyet University [T550]This work was supported by the scientific research fund of Cumhuriyet University under project number T550
Chitotriosidase Levels in the Colostrum from Mothers of Term and Preterm Infants
No full textBackground: Breast milk Chitotriosidase (Chit 1) shows antifungal effect and has an active role in the natural immune response against certain pathogens. The aim of this study was to compare colostrum Chit 1 levels from mothers of term and preterm infants. Materials and Methods: The study included 72 mothers of 32 preterm and 40 term infants (gestational age; 33.7 +/- 1.8 vs. 39.1 +/- 1.1 weeks, birth weight; 1931.7 +/- 539.8 vs. 3350.9 +/- 419.7 g). Breast milk samples were taken at postnatal 24-48 hours. Chit 1 level was evaluated with the quantitative calorimetric method. Results: No significant difference was determined between the term and preterm groups in terms of maternal age, education level, weight gain in pregnancy, and body mass index (BMI). The median colostrum Chit 1 level was higher in the preterm group, but the difference was not statistically significant between two groups (p = 0.43). There is no association between colostrum Chit 1 level, maternal age, gravida, BMI, infant gender, income level, and pre-eclampsia. The colostrum Chit 1 level of mothers who had weight gain exceeding the recommended limits was significantly lower than mothers with weight gain within the recommended limits in the term group (4346.2 vs. 4914.2, p = 0.021). A negative correlation was determined between the birthweight of term infants and the colostrum Chit 1 levels (p = 0.045, r = -0.319). Conclusion: Although the data need to be validated by further investigation, the observations made in this study seem to indicate that colostrum Chit-1 may have role in the protection of preterm infants