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    CRYOPRESERVATION AND ASSESSMENT OF HONAMLI AND HAIR BUCK SEMEN USING RESVERATROL

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    BACKGROUND: Resveratrol (Res) (3,5,4 '-trihydroxystilbene) is a natural polyphenol that exhibits important biological activities. OBJECTIVE: To assess the effects of resveratrol (Res) on freeze-thawed survival of semen from Honamli and Hair Bucks. MATERIALS AND METHODS: Six bucks, aged 2-3 years (three from each breed), were included in the study. Semen was collected from each breed and mixed separately after removing seminal plasma. The mixed semen was diluted with different Res concentrations (0 mu M as control, 25 mu M, 50 mu M, 100 mu M, 500 mu M, and 1 mM) in Tris diluent and subjected to cryopreservation in liquid nitrogen vapor and frozen. After thawing, the samples were evaluated for motility and some spermatologic quality parameters by flow cytometry. RESULTS: Data were analyzed separately for Honamli and Hair breeds. The results showed that the Res 1 mM group had the lowest motility in all assessments (P0.05). In terms of apoptosis, Hair bucks exhibited a statistically significant difference in late apoptotic parameters, with the control showing the highest values (P<0.05). The Res 25 mu M group (similar to the control group) showed lower mitochondrial oxidative stress than the Res 1 mM group (P<0.05). CONCLUSION: Res at a dose of 1 mM did not protect most sperm functional and biochemical parameters except for apoptosis and performed worse than the control group. When all parameters are evaluated collectively, concentrations lower than 1 mM should be used for freezing Honamli and Hair Buck semen with resveratrol.Burdur Mehmet Akif Ersoy University Scientific Research Projects Coordination [0726-MP-21/2017K12-41003]This research was supported by Burdur Mehmet Akif Ersoy University Scientific Research Projects Coordination, Project No. 0726-MP-21/2017K12-41003

    The Development of Children's Musical Thinking

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    Bu çalışma, 1-6 yaş arası çocukların müziksel düşüncelerinin gelişimi, bu süreçteki kritik dönemler ve müzikle kurdukları etkileşimlerin bilişsel, duygusal ve sosyal gelişim üzerindeki etkilerini incelemek amacıyla gerçekleştirilmiştir. Sistematik bir alanyazın taraması ile gerçekleştirilen araştırma, çocukların müziksel keşiflerinden müziksel beceri gelişimine, düşünme süreçlerinin oluşumu ve kavrayışın derinleşmesine kadar olan evreleri ele alan bilimsel çalışmaları bir araya getirmiştir. Özellikle 4-5 yaş grubunda, çocukların ritim ve melodi farkındalığını artırdıkları, çeşitli çalgıları tanımaya başladıkları ve müzik aracılığıyla kendi duygularını ifade edebildikleri görülmüştür. Doğaçlama ve yaratıcılık bu dönemde önemli bir rol oynarken, çocukların müziksel düşünmelerinin temel yapı taşları olarak ortaya çıkmaktadır. Araştırma ayrıca çocukların müzik eğitimi yoluyla nasıl bir müziksel kimlik oluşturduklarını ve hangi müziksel becerileri geliştirdiklerini de ele almıştır. Elde edilen bulgular, yaratıcı müzik etkinliklerinin çocukların müziksel düşüncelerini ve genel gelişimlerini desteklediğini vurgulamaktadır. Müzik eğitimi süreçlerinde, çocukların müziksel çeşitliliği keşfetmesinin, topluluk müzisyenliği deneyimlerinin ve ebeveyn-çocuk etkileşimlerinin gelişime önemli katkılar sağladığı belirtilmektedir.This study was conducted to examine the development of musical thinking in children aged 1-6, the critical periods in this process, and the impact of their musical interactions on cognitive, emotional, and social development. Through a systematic literature review, the research brings together scientific studies that explore various stages, ranging from children's musical exploration to the development of musical skills, the formation of thinking processes, and the deepening of comprehension. It has been observed that, particularly in the 4-5 age group, children enhance their awareness of rhythm and melody, begin to recognize different musical instruments, and express their emotions through music. Improvisation and creativity play a crucial role during this period, emerging as fundamental components of children's musical thinking. The study also examines how children construct a musical identity through music education and what musical skills they develop. The findings emphasize that creative musical activities support children's musical thinking and overall development. Furthermore, it is highlighted that exploring musical diversity, engaging in ensemble music-making experiences, and fostering parent-child interactions significantly contribute to children's development in the context of music education

    Experiences of physical therapists applying telerehabilitation to neurological patients: A qualitative study

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    Background: Telerehabilitation has been widely used in neurological diseases in recent years. The experiences of physical therapists and the difficulties they face are critical to the effectiveness of telerehabilitation. Objective: To examine in depth the technical challenges, patient interaction strategies, and session management processes faced by physical therapists who use telerehabilitation for patients with neurological conditions and to assess the opinions of physical therapists about the advantages, disadvantages, technological infrastructure needs, and support strategies of telerehabilitation. Methods: In this study, phenomenological qualitative research method was used. In-depth interviews were conducted with eight physical therapists who treated patients with neurological disorders with telerehabilitation in our country. Interview data were analyzed using content analysis. Results: The analysis revealed seven key themes and 26 sub-themes, which were categorized into two main areas: telerehabilitation session management and perceptions of telerehabilitation sessions. In the area of session management, physical therapists reported challenges related to the adaptation of traditional rehabilitation techniques to the online environment, including difficulties with assessing patients' physical conditions remotely, ensuring patient engagement, and managing technical issues such as internet connectivity and software limitations. They also highlighted the importance of clear communication, structured session planning, and the need for additional training to effectively conduct telerehabilitation sessions. Conclusions: Considering the advantages and disadvantages stated by physical therapists using telerehabilitation with patients with neurological conditions, solutions should be developed to increase the efficiency of telerehabilitation. Applications with simple interfaces, a home environment suitable for exercise sessions, and strategies to support technology adaptation can significantly improve the efficiency of telerehabilitation

    Tourism's hidden gem: Niche tourism unveiled through resident insights

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    Niche tourism has emerged as a pivotal strategy in mitigating tourism's negative environmental, economic and sociocultural impacts. Previous studies highlight the importance of niche tourism as a counterbalance to mass tourism, fostering sustainable tourism development. This chapter, utilizing the stimulus-organism-response (SOR) theory, investigates how residents' attachment to their community and perceptions of mass tourism influence their attitudes towards niche tourism development. Additionally, it examines how these attitudes predict their support for niche tourism and expectations of its potential benefits. Data was collected through quantitative research conducted in Manavgat, Türkiye, a region characterized by intense mass tourism development. Results indicated that strong community ties and negative perceptions of mass tourism significantly enhanced favourable attitudes towards niche tourism. Furthermore, residents' attitudes towards niche tourism development significantly predicted their support for niche tourism and their expectations of its benefits. The chapter highlights the importance of involving residents in sustainable tourism practices, which can lessen the negative effects of mass tourism and support sustainable niche tourism development. These findings provide valuable guidance for policy makers and practitioners in crafting sustainable tourism strategies that meet the needs and expectations of local communities. © CAB International 2025. Niche Tourism and Sustainability: Perspectives, Practices and Prospects (eds A. Farmaki et al.). All rights reserved

    The relationship between work motivation and productivity: Bibliometric analysis of articles from 1953 to 2024

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    BackgroundMotivation plays an important role in helping humans take action and work effectively and efficiently. It is important to understand the relationship between work motivation and productivity and to examine the factors associated with them.ObjectiveThis study aimed to conduct a bibliometric analysis of publications on motivation and productivity between 1953 and 2024 and to determine the main findings, most popular variables, and methodologies in these publications.MethodsData were downloaded from the Scopus database and 3363 articles on the subject published between 1954 and 2024 were examined. A comprehensive bibliometric analysis was performed using the Biblioshiny application of the Bibliometrix package and the VOSviewer program.ResultsThe study showed an increase in work motivation and productivity publications. The USA, the most cited, collaborative, and productive country, leads all studies. The study presents the most productive authors in this field, the most published journals, the most productive countries, the most used keywords by authors, and trending topics.ConclusionsDeveloping appropriate working conditions and strategies that will increase the motivation of humans can maximize their potential and productivity. Especially psychology and management, studies are carried out in many fields such as education, health, and engineering. This research provides future researchers with a roadmap to in-depth exploration of the field and potential advances

    Evaluation of the effect of different root canal disinfection procedures on postoperative pain

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    Bu çalışmada geleneksel iğne irrigasyonu, sonik aktivasyon, pasif ultrasonik aktivasyon ve KTP lazer ile yapılan kök kanal dezenfeksiyonu işlemlerinin postoperatif ağrı üzerine etkisi araştırıldı. Çalışmaya asemptomatik devital tek kök ve tek kanallı mandibular premolar dişe sahip olan 80 hasta katıldı. Hastalar rastgele dört gruba ayrılarak her bir gruba farklı final irrigasyon ve dezenfeksiyon prosedürü uygulandı; geleneksel iğne irrigasyonu (Gİİ), sonik irrigasyon (Sİ), pasif ultrasonik irrigasyon (PUİ) ve KTP lazer ile dezenfeksiyon. Mandibular anestezi uygulanarak rubber dam ile izole edilen dişe giriş kavitesi açıldı. Çalışma boyu belirlenerek kök kanal preparasyonu One Curve döner alet sistemi kullanılarak yapıldı. Preparasyon işlemleri sırasında toplam 6 ml %2,5'lik NaOCl solüsyonuyla 31 G yandan delikli irrigasyon iğnesi kullanılarak 2 ml/20 sn hızla irrigasyon yapıldı. Daha sonra önceden belirlenen aktivasyon ve dezenfeksiyon gruplarına göre son irrigasyon prosedürü uygulandı. Son irrigasyon, toplam 6 ml %2,5'lik NaOCl solüsyonu ile her biri 20 sn uygulanan üç irrigasyon döngüsünden oluştu. Her irrigasyon döngüsü sonrasında Gİİ ve KTP lazer grubunda 20 sn bekleme, Sİ ve PUİ gruplarında ise 20 sn aktivasyon yapıldı. Daha sonra 2 ml %17'lik EDTA ile 1 dk süreyle irrigasyon yapılarak sonrasında 1 dk bekleme/aktivasyon yapıldı. Son yıkama solüsyonu olarak 2 ml distile su kullanıldı. KTP lazer grubunda steril kağıt konlarla kurulanan kök kanalına KTP lazer uygulandı. Kök kanalı guta perka ve AH Plus patı kullanılarak tek kon tekniğiyle dolduruldu. Dişin, aynı seansta rezin kompozit restorasyonu yapıldı. yapıldı. Ağrının değerlendirilmesi amacıyla hastaya işlem sonrası ağrı değerlendirme formu verilerek ağrının şiddetini 6, 24, 48 ve 72. saat ile 7. günde GAS üzerinde işaretlemesi istendi. 7. gün klinik kontrolü ve perküsyon değerlendirmesi yapıldı. Veriler; Shapiro-Wilk, varyans analizi, Tukey testi, Bonferroni, Kruskal-Wallis testi, Man Whitney U testi, Friedman testi, Wilcoxon testi ve Ki-kare testleriyle istatistiksel olarak analiz edilerek anlamlılık düzeyi p0,05). Tüm gruplarda en yüksek postoperatif ağrı skorları 6. saatte kaydedildi. Yaş ve cinsiyet değişkeni postoperatif ağrı düzeylerinde anlamlı fark yaratmazken periapikal lezyonu olan hastalar Gİİ grubunda 6. saatte, Sİ grubunda 48. saatte ve tüm hastalar değerlendirildiğinde ise 48. saatte anlamlı olarak daha düşük postoperatif ağrı skoru bildirdi. Bu çalışmanın sınırlamaları dahilinde uygulanan kök kanal dezenfeksiyon prosedürleri postoperatif ağrı yönünden anlamlı farklılık göstermedi.The effects of root canal disinfection procedures performed with conventional needle irrigation, sonic activation, passive ultrasonic activation, and KTP laser on postoperative pain were investigated in this study. A total of 80 patients with asymptomatic devital single root and single canal mandibular premolar teeth participated in the study. The patients were randomly divided into four groups, and each group received a different final irrigation and disinfection procedure: conventional needle irrigation (CNI), sonic irrigation (SI), passive ultrasonic irrigation (PUI), and KTP laser disinfection. Mandibular anesthesia was administered, and access cavity was prepared in tooth isolated with a rubber dam. The working length was determined and root canal preparation was performed using the One Curve rotary file system. During preparation, irrigation was performed with a total of 6 ml of 2.5% NaOCl solution using a 31G side-vented irrigation needle at a rate of 2 ml/20 sec. Following this, the final irrigation procedure was performed according to the pre-determined activation and disinfection groups. Final irrigation consisted of three irrigation cycles, each applied for 20-sec, with a total of 6 ml of 2.5% NaOCl solution. After each irrigation cycle, a 20-sec resting time was applied in the CNI and KTP laser groups and a 20-sec activation was performed in the SI and PUI groups. Subsequently, irrigation was performed with 2 ml of 17% EDTA for 1 minute, followed by a 1-minute resting/activation. 2 ml of distilled water was used as the final irrigation solution. In the KTP laser group, KTP laser was applied to the root canal dried with sterile paper points. The root canal was filled using the single-cone technique with gutta-percha and AH Plus sealer. Permanent resin composite restoration of the tooth was performed in the same session. To evaluate pain, patient was given a postoperative pain assessment form and were asked to mark the intensity of the pain at 6, 24, 48 and 72 hours, and on the 7th day on a VAS. A clinical follow-up and percussion evaluation were performed on the 7th day. The data were statistically analyzed using Shapiro-Wilk, variance analysis, Tukey test, Bonferroni, Kruskal-Wallis test, Mann-Whitney U test, Friedman test, Wilcoxon test, and Chi-square tests, and the significance level was defined as p0,05). In all groups, the highest postoperative pain scores were recorded at 6 hours. While age and gender did not significantly affect postoperative pain levels, patients with periapical lesions reported significantly less postoperative pain in the CNI group at the 6th hour, in the SI group at the 48th hour, and at the 48th hour when all patients were evaluated (p<0.05). Within the limitations of this study, root canal disinfection procedures performed did not show significant differences in postoperative pain

    Exploring the Influence of a Competitive Environment and Marketing Trends on Sports Coaches' Attitudes Towards Advertising

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    This study examines how commercialization and a competitive environment (CE) in sports have reshaped the role of coaches, positioning them as both athletic leaders and key influencers in marketing trends (MT) and strategies. By exploring coaches' attitudes toward advertising (ATA), it highlights the significance of communication theory in understanding the evolving dynamics of sports marketing. Employing a quantitative survey methodology and structural equation modeling (SEM) analysis, the study investigates the complex interplay among these variables. The findings reveal significant associations between the competitive environment and coaches' attitudes toward advertising, underscoring the importance of strategic marketing initiatives in response to competitive dynamics. Moreover, a substantial correlation is observed between marketing trends and coaches' attitudes toward advertising, emphasizing the need for sports organizations to adapt their marketing strategies to align with current market dynamics. Additionally, the research highlights the multifaceted nature of factors influencing coaches' attitudes toward advertising, including ethical beliefs, adherence to rules, and personal utility. These findings offer valuable insights for developing more effective advertising and marketing strategies tailored to the unique context of sports coaching, contributing to the advancement of marketing practices within the sports industry

    Predictive role of non-viral leukocyte parameters in tracking the development and progression of Crimean-Congo hemorrhagic fever

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    This study aims to investigate the extended leukocyte parameters, known as cell population data (CPD), in Crimean-Congo hemorrhagic fever (CCHF) and to evaluate their diagnostic performance in assessing mortality risk and intensive care unit (ICU) admission requirements. The study included a total of 260 participants, comprising 200 individuals diagnosed with CCHF and 60 healthy controls. CPD analyses were conducted using a Sysmex-XN 9000 complete blood count analyzer. Elevated levels of immature granulocyte (IG) percentage, neutrophil reactivity indices (Ne-X, Ne-Y), dispersion of neutrophil NE-SSC and NE-SFL signals (Ne-WX, Ne-WY), monocyte metabolic activity (Mo-X), and lymphocyte metabolic activity (Ly-X) were observed in CCHF patients compared to controls. Conversely, lymphocyte metabolic activity (Ly-Y) and monocyte fluorescence intensity (Mo-WY) were lower in patients than in controls. In discriminating mortality, IG#, IG%, Ne-WY, and Ly-Y exhibited higher AUC values than other CPDs. Additionally, for predicting ICU requirements, IG#, IG%, and Ne-WY demonstrated higher AUC values compared to other CPDs. IG, Ne-WY, and Ly-Y have the potential to serve as biomarkers for predicting mortality in CCHF. Furthermore, IG and Ne-WY may emerge as innovative and reliable biomarkers for identifying severe cases and predicting ICU admission requirements

    Magnetic deep eutectic solvents for vortex-assisted liquid phase microextraction method for selective and green extraction of patulin from fruits and fruit juices

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    In this study, a vortex assisted magnetic deep eutectic solvent based liquid phase microextraction (VA-MDESLPME) technique was developed for the extraction of patulin prior to its determination by ultraviolet-visible spectrophotometry (UV-Vis). For this purpose, the use of a magnetic deep eutectic solvent (MDES) consisting of trihexyltetradecylphosphonium chloride, MnCl2, and octanoic acid (molar ratio 1:2:2) was tested to perform an efficient extraction. Important experimental parameters (MDES-3 vol, pH, vortex time, and ethanol volume) were optimized using Box-Behnken Design. Under optimum conditions (MDES-3 vol 560 mu L, pH 3.5, vortex time 300 s, and ethanol volume 300 mu L), the limits of detection for the model solution and matrix-matched solution were 0.06 ng mL- 1 and 0.37 ng mL- 1, and the calibration ranges were 0.2-400 ng mL- 1 and 1.2-300 ng mL- 1, respectively. Furthermore, the extraction recovery was calculated to be 96.3-97.4 % with a low relative standard deviation (2.1-2.5 %). The VA-MDES-LPME technique was successfully applied for the determination of patulin from fruit and juice samples with an enrichment factor between169 and 185.National Science Centre, Warsaw, Poland [UMO-2018/30/E/ST8/00642]Financial support from the National Science Centre, Warsaw, Poland - decision no. UMO-2018/30/E/ST8/00642. is highly acknowledged by Hameed Ul Haq and Grzegorz Boczkaj

    Thermodynamic properties of a Gaussian quantum ring in the presence of a molecular ion

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    In this study, the findings of research conducted into the thermodynamic properties of a molecular complex ion in a 2D quantum ring characterized by Gaussian-type potentials are presented. The Schr & ouml;dinger equation for a singly ionized double donor complex was solved by a two-dimensional diagonalization method. The results obtained show that at the internuclear distance, where there is coupling between the Coulomb centers such that the electron is shared by both impurity atoms, the mean energy and entropy of the system are minimal. A further finding is that in the regime where the distance between impurity atoms is comparable to the inner radius of the quantum ring, the heat capacity of the system undergoes significant changes with temperature.Scientific and Technological Research Council of Turkiye (TUBITAK)Open access funding provided by the Scientific and Technological Research Council of Turkiye (TUBITAK)

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