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Doğal yolla ve YÜT tedavisi ile gebe kalan kadınların perinatal bağlanma düzeylerinin annelik fonksiyonel durumu ile ilişkisi
No full textİnfertilite tedavilerinin artmasıyla gebeliğin elde ediliş şeklinin anne adayının psikolojik durumu, bağlanma süreci ve anneliğe geçiş süreci üzerindeki etkileri önemli bir araştırma alanı olmuştur. Bu araştırma, doğal yolla ve yardımcı üreme teknikleri (YÜT) ile gebe kalan kadınların perinatal bağlanma düzeylerini, annelik fonksiyonel durumlarını ve bunların sosyodemografik, obstetrik ve psikososyal faktörlerle ilişkisini incelemek amacıyla gerçekleştirildi. YÜT ile gebe kalan kadınların deneyimlerinin, dgebe kalanlarla karşılaştırıldığında nasıl farklılaştığını ve bu farklılığın bağlanma, ruhsal sağlık ve annelik fonksiyonlarına etkisini belirlemek hedeflendi. Örneklem grubunu, bir kamu hastanesi ve özel bir tüp bebek merkezine başvuran toplam 106 kadın (53'ü YÜT, 53'ü doğal yolla) oluşturdu. Veriler yapılandırılmış anket, Prenatal Bağlanma Envanteri, Maternal Bağlanma Ölçeği, Barkin Annelik Fonksiyonu Ölçeği ve Depresyon, Anksiyete, Stres Ölçeği kullanılarak Aralık 2021-Şubat 2023 tarihleri arasında toplandı. YÜT grubunda yaş ortalamasının daha yüksek olduğu, cerrahi oranlarının ve gebelik öncesi bilgi alma oranlarının daha fazla olduğu bulundu. Maternal Bağlanma puanları YÜT grubunda anlamlı şekilde yüksek (YÜT: 99.47 ± 5.09, Doğal Yolla: 96.98 ± 6.89; Z = -2.079; p = .038) çıkarken, diğer ölçeklerde grup farkı saptanmadı (p>0.05). Her iki grupta da doğum sonrası depresyon puanlarında doğum öncesine kıyasla azalma gözlemlendi. (YÜT: 9.64 ± 6.75, Doğal Yolla: 10.08 ± 6.26; Z = -0.491; p = .624). Ancak gruplar arasında istatistiksel olarak anlamlı bir fark bulunamadı. Sosyodemografik özelliklerin bağlanma düzeylerini etkilediği ve eğitim düzeyinin bağlanmada önemli bir faktör olduğu belirlendi. Sonuçlar, sağlık hizmetlerinin bireyselleştirilmesi ve psikososyal desteklerin artırılması gerektiğini gösterdi. Bu çalışma, perinatal dönemde bütüncül sağlık hizmetleri sunulması ve kadınların bireysel ihtiyaçlarına odaklanılması gerektiğine dair önemli veriler sundu. Anahtar Kelimeler: Annelik Fonksiyonel Durumu; Doğal Yolla Gebelik; Perinatal Bağlanma; Yardımcı Üreme Teknikleri.
With the growing use of infertility treatments, the psychological impact of pregnancy origin on maternal bonding and transition to motherhood has become increasingly important. This study aimed to compare the perinatal attachment levels and maternal functional status of women who conceived through natural conception and through assisted reproductive technologies (ART), and to explore how these outcomes relate to sociodemographic, obstetric, and psychosocial factors. The sample consisted of 106 pregnant women (53 ART, 53 natural conception) treated at a public hospital and a private IVF clinic. Data were collected between December 2021 and February 2023 using structured questionnaires, the Prenatal Attachment Inventory, the Maternal Attachment Scale, the Barkin Maternal Functioning Scale, and the Depression, Anxiety, and Stress Scale. The ART group showed significantly higher maternal attachment scores compared to the natural conception group (ART: 99.47 ± 5.09; natural conception: 96.98 ± 6.89; p = .038). No significant group differences were found in other scales. Both groups experienced a decrease in postpartum depression scores compared to pre-birth levels, though this change was not statistically significant. Findings indicated that sociodemographic characteristics, particularly education level, were influential in attachment outcomes. The study highlights the necessity of individualized perinatal care and enhanced psychosocial support for pregnant women, especially those undergoing ART. These findings underscore the importance of tailoring healthcare services to meet the psychological and emotional needs of expectant mothers. Keywords: Assisted Reproductive Technologies; Maternal Functional Status; Natural Conception; Perinatal Attachment
The effect of pelvic floor muscle exercises on sexual life in women with overactive bladder
No full textYılmaz Aladağ, F. (2025). Aşırı Aktif Mesaneli Kadınlarda Pelvik Taban Kas Egzersizlerinin Cinsel Yaşam Üzerine Etkisi. Doktora Tezi, Biruni Üniversitesi Lisansüstü Eğitim Enstitüsü, İstanbul. Aşırı aktif mesaneli kadınlarda pelvik taban kas egzersizlerinin (PTKE) cinsel yaşam üzerine etkisinin incelenmesi amacıyla yapılan bu çalışma, 1 Aralık 2021- 1 Aralık 2024 Tarihleri arasında Erzurum Şehir Hastanesi Üroloji Polikliniğine başvuran 64 kadın (32 kadın: müdahale grubu, 32 kadın: kontrol grubu) ile yürütüldü. Çalışma verileri Kişisel Bilgi Formu, Üriner Günlük Takip Formu, Aşırı Aktif Mesane Sorgulama Formu (AAM-V8), Kadın Cinsel İşlev Ölçeği (KCİÖ), Cinsel Yaşam Kalitesi Ölçeği-Kadın (CYKÖ-K) Epidemiyolojik Araştırmalar Merkezi Depresyon Skalası (EAMDS), Pelvik Taban Kas Egzersiz Uygulama Takip Formu, Digital palpasyon (pelvik taban kas gücü ölçümü) ile toplandı. Müdahale grubuna PTKE (Pelvik Taban Kas Egzersizi), 6 hafta boyunca, PTKE uygulama prosedürü doğrultusunda Simplex Cihazı ile biofeedback yaptırılarak uygulandı. Kontrol grubunun uygulama sonrası yapılan değerlendirmede AAM-V8, KCİÖ, CYKÖ-K, EAMDS, kasılma gücü, gevşeme gücü, maksimum istemli kasılma (MVC) % değeri ve pelvik taban kas gücü ortalamaları sırasıyla 35.72±2.77, 20.68±4.81, 36.60±27.14, 37.78±9.25, 5.60±2.34, 2.54±1.46, 40.02±9.26 ve 0.41±0.56, müdahale grubunun uygulama sonrası yapılan değerlendirmede AAM-V8, KCİÖ, CYKÖ-K, EAMDS, kasılma gücü, gevşeme gücü, MVC % değeri ve pelvik taban kas gücü ortalamaları sırasıyla 2.84±4.00, 18.06±3.58, 81.70±14.34, 10.25±11.56, 28.41±10.77, 2.39±0.63, 52.69±5.92 ve 4.38±0.71 saptandı. Yapılan analizlerde uygulama sonrası yapılan değerlendirmede AAM-V8, KCİÖ, CYKÖ-K, EAMDS, kasılma gücü, MVC % değeri ve kas gücü değişkenlerinde gruplar arasında istatistiksel olarak anlamlı fark saptandı (p<0.05). Pelvik taban kas egzersizi yapan grubun AAM semptomları, cinsel işlev bozukluğu ve depresyon ve pelvik taban kas gevşeme puanları daha düşük, cinsel yaşam kalitesi, pelvik taban kas kasılma gücü, MVC % değeri ve kas gücü puanlarının daha yüksek olduğu belirlendi. Anahtar kelimeler: Aşırı Aktif Mesane; Kadın Cinsel Fonksiyon, Pelvik Taban Kas Egzersizleri.Yılmaz Aladağ, F. (2025). The Effect of Pelvic Floor Muscle Exercises on Sexual Life in Women with Overactive Bladder. Doktorate Thesis, Biruni University Postgraduate Education Institute, Istanbul. This study, which was conducted to examine the effect of pelvic floor muscle exercises (PFME) on sexual life in women with overactive bladder, was conducted with 64 women (32 women: intervention group, 32 women: control group) who applied to Erzurum City Hospital Urology Polyclinic between December 1, 2021 and December 1, 2024. The study data were collected by Personal Information Form, Urinary Diary Follow-up Form, Overactive Bladder Questionnaire (OAB-V8), Female Sexual Function Scale (FSFS), Sexual Quality of Life Scale-Woman (SQLS-W), Epidemiological Research Center Depression Scale (ERCDS), Pelvic Floor Muscle Exercise Application Follow-up Form, Digital palpation (pelvic floor muscle strength measurement). In the intervention group, PTKE (Pelvic Floor Muscle Exercise) was performed for 6 weeks with biofeedback with the Simplex Device in accordance with the given PTKE application procedure. The mean scores of OAB-V8, FSFS, SQLS-W, ERCDS, contraction strength, relaxation strength, Maximum voluntary contraction (MVC) value and muscle strength of the control group were 35.72±2.77, 20.68±4.81, 36.60±27.14, 37.78±9.25, 5.60±2.34, 2.54±1.46, 40.02±9.26 and 0.41±0.56, while the mean values of OAB-V8, FSFS, SQLS-W, ERCDS, contraction strength, relaxation strength, MVC % value and muscle strength of the intervention group were 2.84±4.00, 18.06±3.58, 81.70±14.34, 10.25±11.56, 28.41±10.77, 2.39±0.63, 52.69±5.92, and 4.38±0.71, respectively. Statistically significant differences were found between the groups in OAB-V8, FSFS, SQLS-W, ERCDS, contraction strength, MVC % value, and muscle strength variables (p<.05). It was determined that the pelvic floor muscle exercise group had lower OAB symptoms, sexual dysfunction and depression and pelvic floor muscle relaxation scores, and higher sexual quality of life, pelvic floor muscle contraction strength, MVC % value, and muscle strength scores. Keywords: Overactive Bladder; Pelvic Floor Muscle Exercises; Women Sexual Function
Niacin Modulates SIRT1-Driven Signaling to Counteract Radiation-Induced Neurocognitive and Behavioral Impairments
Full text linkAbstract
Radiation exposure causes neuroinflammation, oxidative stress, and neuronal loss, leading to cognitive and behavioral impairments. This study aims to evaluate the effect of niacin interventions on whole-brain irradiation (WBI)-induced cognitive and behavioral impairment. Female Wistar rats were randomly assigned to Control (Group 1), Radiation +Saline (Group 2), and Radiation +niacin (Group 3) groups. Rats in the irradiated groups (Groups 2 and 3) received a single dose of 20 Gy photon irradiation. Group 2 received water seven days after irradiation, while Group 3 received niacin (60 mg/kg, 2 mL) oral gavage for 15 days. On days 22, 23, and 24, behavioral assessments were performed, including the Open Field Test, the Sociability Test, and the Passive Avoidance Learning (PAL) task. Biochemical analyses included MDA, BDNF, TNF-alpha, CREB), SIRT1, and SIRT6 measured by ELISA. Histological assessments included neuronal density and GFAP immunostaining in CA1 and CA3 regions of the hippocampus and cerebellar Purkinje neurons. Radiation exposure importantly increased MDA and TNF-alpha levels, while SIRT1, SIRT6, BDNF, and CREB were notably reduced. This was accompanied by neuronal loss in the cerebellum and hippocampus, astrogliosis, and behavioral and cognitive deficits. Niacin treatment significantly decreased MDA and TNF-alpha levels while increasing BDNF, CREB, SIRT1, and SIRT6 expression, attenuating neuronal apoptosis. Immunohistochemical analysis demonstrated that niacin treatment enhanced neuronal density in the CA1 and CA3 regions of the hippocampus and cerebellar Purkinje neurons while reducing GFAP immunoreactivity in the CA1, CA3, and cerebellum following WBI. Behaviorally, niacin treatment improved social interaction, locomotor activity, and memory performance, underscoring its neuroprotective potential against WBI-induced damage. These findings suggest that niacin may ameliorate behavioral and cognitive impairments following whole brain irradiation by activating the SIRT1/CREB/BDNF or SIRT1/SIRT6/MDA/TNF-alpha signaling pathway
Corrigendum to “Effect of manufacturing trinomial and preparation design on the fabrication and fit accuracy of additively and subtractively manufactured resin-based overlay restorations
Full text link[Journal of Dentistry 157
(2025) 105687
"Prevalence of Candida albicans in High-Risk Human Papillomavirus-Positive Women: A Study in Diyarbakır Province, Turkey"
Full text linkE. Oktay Gultekin, T. Mecit, and B. Can, “Prevalence of
Candida albicans in High-Risk Human PapillomavirusPositive Women: A Study in Diyarbakır Province, Turkey,”
Canadian Journal of Infectious Diseases and Medical Microbiology 2023, no. 1 (2023), https://doi.org/10.1155/2023/
9945561.
Te author list incorrectly omitted the author “Tarık
Mecit”.
Te corrected author list should read: Efdal Oktay
Gultekin, Tarık Mecit, and Behzat Can.
Te author contributions statement should read as
follows:
E. Oktay Gultekin planned the study, supplied the
materials, carried out the laboratory work, performed statistical analysis, and wrote the article.
T. Mecit: Project administration, visualization, and
writing–review & editing.
B. Can collected the sample, collected the participant
data, analyzed the data, collected and processed the data, and
critically reviewed the article.
We apologize for this error. Te author list and contributions statement in the original article has since been
updated accordingly
Palladium (II)-NNN Pincer Complex Embedded Carbon Felt Electrode for High-Performance Symmetrical Supercapacitor Applications
Full text linkAbstract
Pincer-type ligands are coated on the carbon felt (CF) surface in one step via the electrodeposition method, and their use as supercapacitor electrode materials is reported for the first time in this research study. Raman spectroscopy, X-ray diffraction, scanning electron microscopy-energy dispersive X-ray analysis and mapping, and X-ray photoelectron spectroscopy are used to characterize the bis(pyridyl) iminoisoindoline (BPI) derivates/CF electrodes. The galvanostatic charge-discharge study indicates that the calculated specific capacitance (Cs) of the PdBPI/CF electrode is 271.2 F g-1 at 1.0 mA current. The symmetrical supercapacitor has a high capacitance retention of up to 80.6% after 10 000 cycles, showing extended cycle life and strong electrochemical stability. The highest energy and power density values obtained for the PdBPI/CF symmetric supercapacitor are calculated to be 25.9 Wh kg-1 and 981.8 W kg-1, respectively
Optical soliton parameter dynamics by variational principle: parabolıc and dual–power laws (super–gaussian and super–sech pulses)
Full text linkAbstract
The current paper retrieves the optical soliton parameter dynamics that is considered with parabolic and dual—power laws of self—phase modulation structures. With linear chromatic dispersion and linear temporal evolution, the variational principle recovered the dynamical system of soliton parameters. Two specific forms of optical solitons are addressed in the paper which are super—Gaussian and super—sech pulses. These typically model RZ and NRZ types of pulses considered in telecommunications engineering. The special cases are naturally revealed when the parameter dictating the generalized nonlinearity is set to unity. The issue of soliton radiation has been tacitly disregarded to keep mathematics simple. The perturbation terms are also taken into account and the extended version of the Euler—Lagrange’s equation displays the extended dynamical system of these soliton parameters. The results naturally involved a range of special functions. © The Author(’s)
Sporcularda el-el bileği, ön kol ve dirsek yaralanmalarına yaklaşım
No full textDAVET YAZISI
Değerli Katılımcılar,
Biruni Üniversitesi, Tıp Fakültesi olarak Spor Yaralanmalarına Genel Yaklaşımlar Kongremizin
yedincisini düzenlemenin gururu ve heyecanı içindeyiz. Kongremiz 27-28 Aralık 2024 tarihlerinde
Biruni Üniversitesi Konferans Salonunda yapılacaktır.
Spor Yaralanmalarına Genel Yaklaşımlar konulu Kongremizinde bundan öncekilerinde olduğu gibi
Spor Yaralanmalarında sık görülen problemleri değerlendirmeyi uygun bulduk. Bu seneki kongremizin
ana temasını “EL, EL BİLEĞİ, ÖNKOL VE DİRSEK BÖLGESİ YARALANMALARI”
oluşturmaktadır. Her biri, birbirinden değerli akademisyenlerimizin destekleriyle multidisipliner bir
yaklaşımla ele aldığımız kongrelerimize, her defasında 400’ün üzerinde bir katılım olması bizi hem
çok mutlu etmekte hem de daha iyisini yapma konusunda heyecanlandırmakta, umutlandırmaktadır.
Bu şevkle VII.sini organize etmeyi planladığımız kongremizde biraz daha spesifik konulara
değinmeyi “EL, EL BİLEĞİ, ÖNKOL VE DİRSEK BÖLGESİ YARALANMALARI”nı ayrıntılı
olarak mercek altına almayı uygun bulduk. Sporcularımızın sağlığı ile bire bir ilgilenen sağlık
profesyonellerimizin değerli katkılarıyla zenginleştirilmiş olan kongremiz açılış konuşmalarını
takiben, 5 oturumda 19 ayrı konu irdelenecek, 1 adet Work-Shop organizasyonu ile
zenginleştirilecektir. Her biri konusunda uzmanlaşmış olan konuşmacılarımızın değerli katkıları ile
bilgilerimizi güncelleme fırsatı yakalayacağımız kongremize katılımlarınız, kongremizin değerini
artıracaktır.
Kongre bildirilerine ait özet metinler e-kitap olarak yayımlanacaktır. Kongremiz Doçentlik ve
Akademik Atama/Yükselme kriterlerini karşılamaktadır.
Bilimsel ve sosyal paylaşımlarının üst düzeyde olmasını temenni eder, saygılarımı sunarım.
Prof. Dr. Mehmet ÜNAL
Kongre Başkan
Impact of High-Intensity Interval Training on Bone Metabolism and the Metabolic and Hormonal Profiles of Postmenopausal Women
No full textAbstract
Introduction: Although many forms of exercise are known to have positive effects on bone metabolism in postmenopausal women, the effect of high-intensity interval training (HIIT) has not been investigated in this setting. This study aimed to evaluate the impact of the 6-week HIIT program on body composition, biochemical parameters, and bone turnover markers in overweight and obese postmenopausal women. Methods: A total of 32 postmenopausal women were randomly assigned to exercise (n=15) or control (n=17) groups. The blood samples and body composition were analyzed. The exercise group participated in a 6-week stationary bike HIIT exercise [(3 days/ week; 30 sec work-90 sec resting intervals with 90-95% of the heart rate reserve-12 to 16 min/day)]. The control group was not involved in any exercise program. Results: In the exercise group, significant reductions were noted in waist and hip circumference, low-density lipoprotein, total cholesterol, triglycerides, phosphorus, calcium, albumin, bone-specific alkaline phosphatase, type 1 collagen C-terminal telopeptide, and osteocalcin levels, in addition to significant increases in high-density lipoprotein, free thyroxine, thyroid-stimulating hormone, vitamin D (25-hidroksi vitamin D), and cortisol levels, when compared with the control group (p<0.05). Conclusion: Our findings revealed the positive effects of the 6-week HIIT training program in postmenopausal women in terms of reduction in waist and hip circumference, improvement in lipid and hormonal profile, and maintenance of bone metabolism. According to our findings, the 6-week stationary bike HIIT exercise was safe and beneficial for postmenopausal women's health
Effects of non-surgical periodontal therapy on gingival crevicular fluid CTRP-1, TNF-α, and IL-10 levels
No full textAbstract
Objectives This study investigated the gingival crevicular fluid (GCF) levels of complement-C1q tumor necrosis factor
related protein-1 (CTRP-1), tumor necrosis factor-α (TNF-α), and interleukin-10 (IL-10) following non-surgical periodontal
therapy (NSPT) in systemically healthy individuals with periodontal health (H), generalized gingivitis (G), and stage III
grade B periodontitis (P). Moreover, this study aimed to investigate their diagnostic potential in distinguishing different
periodontal diseases.
Materials and methods 73 systemically healthy non-smoking individuals were divided into H (n=25), G (n=23) and P
(n=25) groups. Clinical periodontal parameters were recorded, and GCF samples were collected at baseline in all groups,
and 3rd month after NSPT in the G and P groups. GCF levels of CTRP-1, TNF-α, and IL-10 were analyzed using ELISA.
The area under the curve (AUC) was assessed using the receiver operating characteristic curve analysis.
Results CTRP-1 levels were significantly elevated in the G and P group compared to the H group (p<0.001), while there
was no significant difference between the G and P groups (p=0.095). TNF-α and IL-10 levels were significantly higher in
the P group compared to the other groups (p<0.001). GCF CTRP-1 demonstrated an excellent diagnostic performance to
discriminate periodontitis and gingivitis from periodontal health (AUC value of 0.998 and 0.974 with 100% and 91.3%
sensitivity).
Conclusion CTRP-1 could serve as a potential biomarker for periodontal diseases. CTRP-1 demonstrated excellent diagnostic performance in distinguishing stage III grade B periodontitis and gingivitis from periodontal health.
Clinical relevance GCF CTRP-1 levels may serve as a valuable marker for diagnosing periodontal diseases