Biruni University Institutional Repository
Not a member yet
2908 research outputs found
Sort by
Bifurcation dynamics and optical soliton structures in the nonlinear Schrödinger-Bopp-Podolsky system
No full textIn this article, the complex structure of optical soliton solutions of the nonlinear Schr & ouml;dinger-Bopp-Podolsky system is investigated using the enhanced modified extended tanh-expansion approach. It also analyzes the system's stability and how it changes by performing a bifurcation analysis. This system holds special importance in nonlinear optics because it describes light-wave behavior when they interact with nonlinear materials. The enhanced modified extended tanh-expansion method serves as a strong analytical method to construct numerous innovative and diverse optical solitons including dark and bright and singular types. The obtained solutions help researchers understand all aspects that influence the nonlinear Schr & ouml;dinger-Bopp-Podolsky system behavior while providing tools for simulating nonlinear optical processes. The potential for discovering new types of optical soliton solutions specific to the Schr & ouml;dinger-Bopp-Podolsky system, which may differ from those found in other systems, remains untapped. While the current literature demonstrates the effectiveness of the enhanced modified extended tanh-method in various contexts, its application to the nonlinear Schr & ouml;dinger-Bopp-Podolsky system could provide new insights and expand the understanding of soliton dynamics in modified nonlinear systems.This study is innovative because it is the first to apply the enhanced modified extended tanh-method to the nonlinear Schr & ouml;dinger-Bopp-Podolsky system. This approach enables the construction of new soliton solutions and provides a deeper understanding of the nonlinear dynamics of the system. We employed Mathematica and MATLAB together to provide comprehensive, illustrative, and high-quality visualizations of the findings for graphical representation
Findings From the Great British and Northern Ireland Botulinum Toxin Survey: Treatment Outcomes, Patient Experience, and Regulations From a Cross-Sectional Survey
No full textBackground Given rising demand for botulinum toxin (BoNT) treatments and limited data on safety, ethics, and regulation, a national survey explored experiences with cosmetic BoNT in the United Kingdom.Objectives To conduct a national observational survey with the aim to capture real-world experiences of cosmetic BoNT in the United Kingdom.Methods A cross-sectional online survey gathered data on experiences with cosmetic BoNT injections across the United Kingdom. Participation was open to adults (>= 18 years) who had received cosmetic BoNT treatment.Results A total of 919 participants completed the survey and were predominantly female, white, and had a high household income. Commonly reported acute complications were bruising/swelling (26.1%), and headache (24.7%). Commonly reported long-term complications were BoNT resistance (2.9%), social withdrawal (2.7%), nerve damage (2.5%), and dry eyes/vision problems (2.5%). In total, 66% stated their treatment was administered by a prescriber, 28% said it was not. Among those treated by a non-prescriber, 40% reported that a prescriber was present during the consultation, 42% said no prescriber was present, and 17% were unsure. Surprisingly, a few had not signed a consent form (8%), 11% were not informed of treatment risks, and 18% were not told how to respond to complications. A large majority expressed support for enhanced oversight, with 57.8% favoring significantly stricter regulation, and 31.3% somewhat stricter regulation.Conclusions Cosmetic BoNT can offer high satisfaction and a favorable safety profile when administered appropriately. However, findings highlight key vulnerabilities: inconsistent practitioner qualifications, gaps in informed consent, insufficient complication support, and weak regulation
Study of Monkeypox Virus Transmission Dynamics: Vaccination Effect and Sensitivity Analysis
No full textMonkeypox is an emerging infectious disease from Nigeria that has spread globally, affecting countries such as the USA and the United Kingdom. It belongs to the Poxviridae family under the Orthopoxvirus genus. In this study, we develop a deterministic compartmental model comprising eleven classes: susceptible, vaccinated, exposed, quarantined, hospitalized, and recovered humans, along with susceptible, exposed, infected, and recovered rodents. We analyze the disease-free equilibrium and calculate the basic reproduction number using the next-generation matrix approach. Sensitivity analysis identifies critical parameters influencing disease transmission. Numerical simulations conducted in MATLAB demonstrate that increasing vaccination coverage among humans significantly reduces infection prevalence. The results further reveal that timely quarantine and hospitalization effectively control the spread of the virus. Our findings provide quantitative evidence supporting vaccination and control interventions as vital strategies to mitigate monkeypox outbreaks
VIII. Spor Yaralanmaları Kongresi
No full textBiruni Üniversitesi Tıp Fakültesi ve Spor Fizyoterapistleri Derneği olarak VIII.
Spor Yaralanmaları Kongresi düzenlemenin gururu ve heyecanı içerisindeyiz.
Kongremiz 24-25 Ekim 2025 tarihlerinde Biruni Üniversitesi Konferans
Salonu’nda gerçekleştirilecektir. Her sene düzenli olarak gerçekleştirdiğimiz
kongremizde daha önceki senelerde ayak ve ayak bileği, omuz, diz, kalça ve kasık
bölgesi gibi farklı konular işlenmiştir.
Düzenlenen bu kongreler spor yaralanmaları rehabilitasyonun detaylıca
incelenmesi ve güncel bilgilerin açığa kavuşturulması bakımından son derece
önemlidir. Kongremizde bundan öncekilerinde olduğu gibi spor
yaralanmalarında sık görülen problemleri değerlendirmeyi uygun bulduk. Bu
sene VIII. kez düzenlenecek olan kongremizde konumuz ‘Omurga Bölgesi
Yaralanmaları’ olarak belirlenmiştir. Kongremizde 24 Ekim 2025 tarihinde 5 ayrı
oturumda 15 farklı konu irdelenecek ve bildiriler sunulacaktır. Kongremiz 25
Ekim 2025 tarihinde Postür Değerlenirmesi ve Skolyoz Egzersizleri ile ilgili 2
adet workshop organizasyonu ile tamamlanacaktır. Konular ve akış programımız
bu belge içerisinde ilerleyen maddelerde detaylı olarak açıklanmıştır.
Kongremizin amacı spor yaralanmaları ve rehabilitasyonu alanında Dünya
genelindeki gelişmeleri yakından takip etmek, bu alanda çalışmalarını yürüten
akademisyenlerimizin bilgilerini bu alanda çalışan diğer katılımcılarla
paylaşmalarını sağlamaktır. Her biri konusunda uzmanlaşmış olan
konuşmacılarımızın değerli katkıları ile bilgilerimizi güncelleme fırsatı
yakalayacağımız kongremize katılımlarınız kongremizin değerini artıracaktır
Determination of healthy lifestyle behaviors and pap smeartesting of women aged 18-49
No full textTokuçin, M. (2023). 18-49 Yaş Arası Kadınların Sağlıklı Yaşam Biçimi Davranışları ve Pap Smear Testi Yaptırma Durumlarının Belirlenmesi. Yüksek Lisans Tezi, Biruni Üniversitesi Lisansüstü Eğitim Enstitüsü, İstanbul. Kanser, tüm dünyada ölüm nedenlerinin en yaygın nedenleri arasındadır. Rahim ağzı kanseri (serviks) de yaygın görülen ve önemli ölçüde ölüme neden olan kanser türlerinden birisidir. Pap Smear testi, serviks kanserinin teşhis edilmesinde ve erken önlem alınmasında etkili bir uygulamadır. Bu çalışmanın amacı, 18-49 yaş arası kadınların sağlıklı yaşam biçimi davranışları ve Pap Smear testi yaptırma durumlarını incelemektir. Araştırma İstanbul ilinde bulunan özel bir hastanenin kadın hastalıkları ve doğum polikliniğinde 18-49 yaş arası toplam 353 kadın ile yürütüldü. Veriler Sağlıklı Yaşam Biçimi Davranışları Ölçeği (SYBDÖ) ve Rahim Ağzı Kanseri ve Pap Smear Taraması Sağlık İnanç Modeli Ölçeği (RAKPSİMÖ) kullanılarak karşılıklı görüşme yöntemiyle elde edildi. Kadınların yaş ortalaması 35.07±7.3 idi, %70'i üniversite mezunu ve %60.4'ü evliydi. Kadınların Sağlıklı Yaşam Biçimi Davranışları Ölçeği puan ortalaması 150.87±22.26, Rahim Ağzı Kaseri ve Pap Smear Taraması Sağlık İnanç Modeli Ölçeği puanları ise 9-55 puan arasında değişmekteydi. Eğitim düzeyi yüksek olan kadınların SYBDÖ sağlık sorumluluğu, RAKPSİMÖ sağlık motivasyonu puanı daha fazlaydı. Pap smear testi yaptıran kadınların sağlık motivasyonu puanı daha fazlaydı ve pap smear engel algısı puanı daha düşüktü. Kadınların sağlıklı yaşam biçimi davranışları ile Pap Smear testi yaptırma durumları arasında zayıf düzeyde bir ilişki olduğu saptandı. Kadınların sağlıklı yaşam biçimi davranışlarını ve pap smear yaptırma durumunu eğitim düzeyleri etkilemektedir. Sağlıklı yaşam biçimi davranışları ile pap smear testi yaptırma durumları arasında ilişki bulunmaktadır. Anahtar Kelimeler: Sağlıklı Yaşam, Rahim Ağzı Kanseri (Serviks), Pap Smear Testi.Tokuçin, M. (2023). Determination of Healthy Lifestyle Behaviors and Pap Smear Testing of Women Aged 18-49. Master Thesis, Biruni University Graduate Education Institute, Istanbul. Cancer is among the most common causes of death worldwide. Cervical cancer (cervix) is one of the most common types of cancer that causes significant death. Pap smear test is an effective application for diagnosing cervical cancer and taking early prevention. The aim of this study is to examine the healthy lifestyle behaviors and Pap Smear test status of women aged 18-49. The research was performed with 353 women between the ages of 18-49 in the gynecology and obstetrics polyclinic of a private hospital in Istanbul. Face-to-face interviews obtained data using the Healthy Lifestyle Behavior Scale (HLBS) and the Cervical Cancer and Pap Smear Screening Health Belief Model Scale (CCPSSHBMS). The average age of the women was 35.07±7.3, 70% were university graduates and 60.4% were married. The mean score of the Women's Healthy Lifestyle Behavior Scale was 150.87±22.26, and the scores of the Cervical Casserole and Pap Smear Screening Health Belief Model Scale ranged between 9-55 points. Women with higher education levels had higher HLBS health responsibility and CCPSSHBMS health motivation scores. Women who had a Pap smear test had a higher health motivation score and a lower Pap smear barrier perception score. It was found that there was a weak relationship between women's healthy lifestyle behaviors and their status of having a Pap Smear test.Education levels affect women's healthy lifestyle behaviors and Pap smear status. There is a relationship between healthy lifestyle behaviors and having a pap smear test
The Effects of Different Treatment Procedures Applied to Trigger Finger on Recurrence
No full textIntroduction: To investigate the effects of two different treatment methods on the recurrence rates within one year and on clinical and functional outcomes in patients with trigger finger (TF) complaints. Methods: The files of 137 patients diagnosed with TF at our clinic between 2018 and 2022, who received two different treatments administered by two different physicians, were retrospectively reviewed. After applying the exclusion criteria, the study included 111 patients, of whom 66 underwent surgical release and were designated as group I, and 55 received steroid injections and were designated as group II. The Wolfe grading system was used to evaluate the severity of TF, and the Visual Analog Scale was employed to measure pain levels. Clinical and functional outcomes were assessed at the third and sixth months, and one year after treatment to evaluate the effect of each procedure on the development of recurrence. Results: In group II, the distribution of grade II and grade IIIa recurrence in the first three and six months was found to be statistically significantly higher than in group I (p=0.005 and p=0.045, respectively). In the first year, the distribution of grade II, grade IIIa, and grade IIIb recurrences in group II was also significantly higher statistically compared to group I (p=0.007). No statistically significant difference was observed between group I and group II in terms of the distribution of improvement from baseline to the third and sixth months after treatment (p=0.295 and p=0.118, respectively). All patients in both group I and group II who experienced recurrence were treated surgically. Conclusion: Although the ease of application and rapid effectiveness of steroid injection may appear advantageous compared to surgical methods in the treatment of TF, the high recurrence rates after the first six months negatively affect the potential for sustained success with steroid injection treatment
Chemical composition alterations in rat brain hypothalamus induced by irisin administration using spectroscopic and machine learning techniques
Full text linkABSTRACT
This study employed Fourier transform infrared (FTIR) spectroscopy to determine the chemical composition of
brain tissues and the changes induced by irisin at doses of 50 mg and 100 mg. Brain tissues were collected from
control rats and those administered with irisin, and key vibrational peaks were analyzed. In the 50 mg irisin
group, all described vibrations decreased compared to control tissues, while the 100 mg group showed a decrease
only in lipid vibrations. Comparatively, the 50 mg group had lower absorbance of phospholipids, amides, and
lipid functional groups than the 100 mg group. Lower amounts of these compounds were found in treated tissues
compared to controls, with higher levels in the 100 mg group. Ratios between amide peaks revealed significant
differences between groups. Principal component analysis (PCA) differentiated control and irisin-treated tissues,
primarily using PC1 and PC3. The decision tree model exhibited high classification accuracy, especially in the
800–1800 cm⁻
1 range, with high sensitivity and specificity. FTIR spectroscopy effectively highlighted chemical
changes in brain tissues due to irisin, demonstrating dose-dependent variations. The combination of PCA, ROC
analysis, and decision tree modeling underscored the potential of FTIR spectroscopy for studying the biochemical
effects of compounds like irisin
Thermal characteristics of hybrid Nanofluid (Cu-Al2O3) flow through Darcy porous medium with chemical effects via numerical successive over relaxation technique
Full text linkAbstract
The flow of fluids through porous media is commonly described using the Darcy model, therefore investigating hybrid nanofluids in this setting is rather new. The present work offers insightful information on how the hybrid nanofluids behave and function in porous medium. The study's conclusions may have an impact on a lot of different engineering applications like filtration systems, chemical reactors, and environmental engineering. The study concentrates on a hybrid nanofluid which consists of Cu and Al₂O₃ nanoparticles. The metallic nanoparticles such as copper have high thermal conductivity and non-metallic nanoparticles such as aluminum oxide are chemically stable and has high thermal resistance. This is the reason that the combination Cu-Al₂O₃ is believed to give better heat transfer composite than using individual nanofluids. By employing proper similarity transformation, the governing PDEs are turned into ODEs. To discretize these ODEs, the central finite difference method is used first. Then the successive over relaxation technique is utilized to numerically solve the nonlinear equations. The findings are summarized in a graphical and tabular format. The impacts of several controlling parameters such as porosity, suction, Schmidt number and volume fraction on flow pattern, thermal properties, and concentration are investigated and discussed. The streamwise and normal velocity profiles fall and those of concentration and temperature rise with increase in the values of the porosity parameter
Stochastic gompertzian model for parathyroid tumor growth
No full textAbstract
In this paper, we study on the behavior and growth of parathyroid tumor in the human body. We investigate the change of parathyroid cancer cell with respect to time, obtained from the deterministic Gompertz model through 41 actual patients in the literature. Then we describe the stochastic Gompertz model based on deterministic Gompertz law and obtain the diffusion coefficient for our stochastic model, using the data taken from the patients. We compare the stochastic and deterministic results at the same graph. Also, we numerically solve the defined stochastic differential using the Euler-Maruyama, Milstein, stochastic Runge-Kutta, and Taylor methods. Finally, we demonstrate the effectiveness of each of these methods using graphs and error table
Correlation between serum YKL-40 and VILIP 1 levels and brain volume in dementia patients
Full text linkAbstract
AimAlzheimer's disease (AD) is a chronic, progressive cognitive disorder characterized by prominent episodic memory impairment. The contribution of neuronal damage and neuroinflammation to this process has been investigated by measuring various substances. Two of the most promising substances in serum and plasma studies are visinin-like protein 1 (VILIP-1) and tyrosine (Y), lysine (K), leucine (L)-40 (YKL-40). These markers may lead to early diagnosis and new treatment options.MethodsSerum VILIP-1 and YKL-40 levels were analyzed in 33 probable AD patients and 23 healthy controls. Cranial magnetic resonance imaging (MRI) was used for volumetric measurements. The results were compared with the control group and then the correlation analyze between markers and volumetric measurements of the patient group was achieved.ResultsThe right and left hippocampus and amygdala, left medial temporal, right rostral anterior cingulate, total brain, cortex, white matter, gray matter, subcortical gray matter, right and left total cortex volumes of the probable AD group were significantly lower than those of the control group. In the correlation analysis, the YKL-40 level and left posterior cingulate volume and the VILIP-1 level and left amygdala volume were negatively correlated.ConclusionsIn AD, there is atrophy of the limbic structures, cortex, and white matter. While the relationship between these regions and neurodegenerative markers remains unclear, our findings highlight a notable correlation between YKL-40 and VILIP-1 levels and the left amygdala and left posterior cingulate cortex, respectively. Geriatr Gerontol Int 2025; center dot center dot: center dot center dot-center dot center dot