Jurnal Ilmiah Manuntung
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Dragon fruit is a kind of cactus tree from the family Cactaceae. Red dragon fruit contains lots of vitamin C, vitamin E, vitamin B1, B2, and B3. These vitamins can increase energy, and metabolize food, and even improve skin quality. This study aims to determine whether red dragon fruit skin extract can be made into lotion preparation and to know the effect of variation of red dragon fruit skin extract on physical properties of lotio. Red dragon fruit skin was extracted by maceration, lotio was made using formulation with variation of dragon fruit skin extract which were F1 (3%), F2 (5%), F3 (7%). The lotio was making by mixing the oil phase into the water. Physical test results showed there was organoleptic change in F1, F2 and F3 after observation for 4 weeks. The average result of pH test for four weeks was meet the lotio requirements ranging from 4.5-8. F1 with an average of 6.5, F2 with an average of 7.25, F3 with an average of 7.5. The result of viscosity test is F1 0,5 poise, F2, F3 and F4 0 poise. The result of F1 7.0 cm, F2 7,1 cm and F3 7.5 cm. The irritation test results are not irritating on the use of F1, F2 and F3. The test results showed that F0 and F1 are more favorable. The result of this research was that red skin dragon fruit extract can be made into lotio formulation and there was influence of variation of extract concentration on the physical properties of lotio
Irrational use of drugs is still found in Puskesmas which is the First Level Health Facilities. The use of irrational drugs based on appropriate drugs and precise indications. In the use of various types of drugs there may be an irrationality of treatment, one of which is hypertension.This study aims to determine the antihypertensive drugs used in Pelambuan Puskesmas Banjarmasin and to determine the percentage of rationality of hypertension treatment at Pelambuan Puskesmas Banjarmasin. evaluating the rationale for the use of antihypertensive drugs that include the accuracy of indication, drug, dose, patient, mode of administration, and duration of administration in hypertensive patients at Puskesmas Pelambuan Banjarmasin during 2017. This type of research was descriptive non-experimental research with retrospective data retrieval based on medical records of hypertensive patients in 2017. The population in this study amounted to 333 medical records and the number of samples that met the inclusion and exclusion criteria as much as 37 medical records. The tools / instruments in this study were observation sheets and interview sheets. The results of the research on antihypertensive drugs used in Pelambuan Banjarmasin Health Center were amlodipine, nifedipine, captopril, lisinopril. The results of the evaluation of the rationality of the use of antihypertensive drugs were seen based on the exact indication criteria as many as 18 patients (48,65%), right medication as many as 18 patients (48,65%), right dose of 17 patients (45,95%), right patients as many as 33 patients (89,19%), the exact method of administration was 31 patients (83,79%), and the exact duration of administration was 22 patients (59,46%)
Malaria is one of the health problems in Indonesia. Kanujoso Hospital Djatiwibowo Balikpapan is a referral hospital for Balikpapan, Penajam Paser Utara and Paser. Kabupaten Penajam Paser Utara is the district with the highest incidence of malaria in East Kalimantan. In malaria there is a change of hematology one of them is thrombocytopenia. Several studies have suggested the involvement of thrombocytopenia with severe malaria events. The aim of this reasearch was to know the relations of degree of thrombocytopenia with severe malaria in malaria patients treated at Kanudjoso Djatiwibowo Hospital Balikpapan period 2013-2017.
This research was conducted by using analytic observational research method with cross sectional design. The sample was taken from the patient's medical record at Kanujoso Djatiwibowo Hospital Medical Record Installation for 2013-2017 period with the sample of 81 patients. The data were analyzed by using Fisher test. The results of this research showed that distribution malaria patients based on degree of thrombocytopenia were moderate, severe and mild respectively 41,98%; 40,79% and 17,28%. Severe malaria found in 13.58% patients. We found correlation between degree of thrombocytopenia with severe malaria with Fisfer test ((p=0,043). Our study found correlation between degree of thrombocytopenia with severe malaria in malaria patientspatients at Kanudjoso Djatiwibowo Hospital Balikpapa
Antibiotics and infections are the most common problems faced by developing countries, including in Indonesia. Indonesia awareness of the use of antibiotics rationally decline. Acute respiratory infections ranks first in terms of infant and under-five mortality in developing and developing countries. This research was conducted to see the description of the use of antibiotics in patients with ISPA in Clinic Sint Caroulus Bengkulu from January to December 2014. Data analysis was done by descriptive analysis with retrospective method. The sample calculation was done by using Slovin formula obtained by 100 samples. Of the 100 samples of this study, 57% of men and 43% of women, the age classification of acute respiratory infection was 0% of neonatal patients, 25% of infants, 32% of infants, 20% of children under five, and 23% of children, most antibiotics commonly used with ISPA is cefadroxyl 60% amoxicillin 36% and erythromycin 3%, combination of TMP (trimethoprim) and SMZ (sulfamethoxazole) 1%. The type of ISPA that attack is ISPA non-pneumonia in the form of cough and cold based on medical record data at the Sint Carolus Clinic and patient obtains the drug with a dose in safe range.
Keywords : Antibiotics, Pediatrics, ISP
Currently, there are developed illnesses that encourage humans to do their own alternative medication. In 2002, an estimated shows that 92% of people in the world choose the alternative medication namely self medication, by using over the counter medicine including free and limited, however the level of knowledge in using this medication is still poor, then it is possible to make a mistake. Therefore, this research aims to find out the level of knowledge in using over the counter medicine including free and limited for self medication of society in RW 08, Morobangun, Jogotirto, Berbah, Sleman, Yogyakarta. This study belongs to descriptive observational to find out the subject characteristic, the level of knowledge and the description of the kind of medicine used by society of RW 08 Morobangun. The sample used in this study is the people who lived in Rw 08 Morobangun, Jogotirto, Berbah, Sleman, Yogyakarta. The data was taken from the interview with the patient by using the questionnaire. The sample collecting technique was nonrandom sampling and the method was accidental sampling with the number of the respondents were 175. The result showed that 175 respondents in RW 08 Morobangun, Jogotirto, Berbah, Sleman, Yogyakarta used self medication of over the counter medicine including free and limited only for their ailment. The level of knowledge in using over the counter medicine including free and limited for self medication of society in RW 08 Morobangun, Jogotirto, Berbah, Sleman, Yogyakarta showed that 42.9% reached the good category and 57,1% reached the sufficient category of 175 respondents. The conclusion of this study is the level of knowledge in using over the counter medicine including free and limited for self medication of society in RW 08 showed that most of the respondents achieved the sufficient category with 100 respondents (57,1%)
Diabetes is one of the most common diseases in the world. So there is an effort to prevent or treat the disease. As brown algae (Sargassum sp.) Contains polysaccharides that regulate sugar intake in the body, and polyphenols act as antioxidants that can stimulate insulin secretion in pancreatic β cells. This study aims to determine the effectiveness of Antidiabetes Polysaccharide Extract and Brown Algae Polifenol Compounds (Sargassum sp) On Alloxaninduced Mice. The test animals were grouped into 4 groups I (CMC 1%), Group II (Glibenclamide 0.52mg / 20grBB), Group III (5mg / 20grBB polyphenol extract), Group IV (5mg / 20grBB polysaccharide extract). Blood glucose was measured using Easy touch glucometer on days 0, 3, 7, 14, 21, and 28. Analyze data using one-way ANOVA, followed by LSD test. The percentage decrease in blood glucose level in positive control, polyphenol extract and polysaccharide were 42,86%, 58,12%, and 54,20%. Statistically, the polyphenolic extract and the brown algae polysaccharide lower the blood glucose level significantly compared with the negative control (p≤0,05). Decreased blood glucose in polyphenol extracts and polysaccharides showed statistically significant difference
ABSTRACT
Treatment of respiratory disorders using a metered-dose inhaler (MDI) with spacer becomes one of the important points. Pharmacists at pharmacies are the final key in therapy to ascertain how the use of inhalation tools is correct. This study aims to determine the completeness of each step of information on how to use MDI with spacer given by pharmacists at pharmacies in East Surabaya. The research design used is cross-sectional study with the subject of research is pharmacist in pharmacy. The research variable is the explanation of how to use MDI inhaler with spacer. An assessment method of 8 steps on how to use MDI with spacer and each number gets a value. Research subjects were 22 pharmacists. Most pharmacists describe each step orally by using the tool directly, ie at step: 1a (77.27%), 1b (77.27%), 2 (81.81%), 3 (31.81%) , 4a (59.09%), 4b (13.63%), 5a (100%), 5b (63.63%), 6a (90.90%), 6b (40.90%), 8a (9 , 09%), and 8b (9.09%). Most of the pharmacists explain verbally with a demonstration tool but only one pharmacist can explain all the steps completely. Therefore, pharmacists need to improve IEC services related to the use of MDI with a spacer for respiratory treatment.
Keywords : information on how to use inhaler, Metered-Dose Inhaler (MDI), spacer, pharmacist, pharmac
Dysmenorrhea is a pain before or during the menstrual period. The impact of dysmenorrhea are the disruption on physical function, emotional, social and school activities and disruption of quality of life. The study purpose is to detect the quality of life of adolescents with dysmenorrhea.The research method was a quantitative descriptive with total sampling technique to 195 students which selected using dysmenorrhea screening. The data were collected using the pediatric quality of life 4.0 generic module (PedsQL) teens report in Indonesian version which the validity and reliability have been tested. Analysis of data has been done to find out the mean value in each dimension and frequency distribution. The results showed that the mean value of the quality of life of adolescents with dysmenorrhea in general was 62,04 ± 8,15 and 51,8% was in the low. The mean value in physical dimension was 49,36 ± 9,19, emotional dimension was 57,62 ± 13,16, social dimension was 86,38 ± 13,28, and in the school dimension was 62,41 ± 14,77. The quality of life in high categories were in the emotional dimension (60,0%), social dimension (64,1%), and school dimension (60,5%). Meanwhile, the quality of life in low category was in the physical dimension (57,4%). It showed that the quality of life of adolescents with dysmenorrhea in SMK Negeri 2 Sumedang were low. It was recommended to the school and the health office in Sumedang district to provide the reproductive health education, specifically about the prevention and the treatment of dysmenorrhea on adolescents.
 
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, which mostly (80%) attacks the lungs. Tuberculosis is one of the diseases that attacks people with the relatively high percentage and can effect in death. This study aims to determine how the use of anti-tuberculosis drugs in TB patients cause bad side effects and how the treatment of the side effect.The method of this research is descriptive with cross sectional study design. The sampling techniques are Retrospective and Prospective research. The data tabulation taken by distributed questionnaires and interviews to the TB patients and health worker. The data was collected at the Perumnas public health center of Kendari, which was 21 patients who were undergoing treatment stage and also had fulfilled the inclusion criteria that have been determined. The results showed that 21 tuberculosis patients at the Perumnas public health center of Kendari experienced the side-effects such as nausea and vomiting, hematuria, loss of appetite, fever, joint, itch, and skin redness. The most common side effects were queasy and hematuria with the same percentage of 71,5%. The treatment of side effects done by giving the drugs information and providing the drug therapy in agree with the complaints.
Keywords : Tuberculosis, Side-effects, Anti-Tuberculosi
Allergic rhinitis is a common disorder of the breathing that can affect one's productivity and shock. Therefore it is necessary knowledge in self-management to eliminate exposure to allergens that can increase the symptoms of allergic rhinitis. The purpose of this study is to determine the effectiveness of education in improving public knowledge about drugs allergic rhinitis. The research method is experimental pre-sampling with adult sampling through purposive sampling. Measurement of experience conducted for 3 times, ie before getting education (pre test), post-education (post test), and one month after received education (follow up test). The research conducted in May-July 2016, involving 30 people. The results showed that there were significant differences between pre test and post test (0,000 <p (0.05)) and between pre test and follow-up test (0.000 <p (0,05)). However, no changes occurred between post test and follow up test. So education is effective in improving public knowledge in the treatment of allergic rhinitis