Jurnal Ilmiah Manuntung
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No full textPiroxicam, a non steroidal anti inflammatory drugs (NSAID), is an oxicam derivative which can be used for treatment of various rheumatic diseases, such as rheumatoid arthritis and osteoarthritis. Piroxicam patch is an affective approach evading piroxicam’s side effect such as peptic ulcer and first pass metabolism. One of the patch components is polymer that the function is to control the speed of drug release from the patch. The aims of this study were to determine the optimum formula of a combination of polyvinylpyrolidone (PVP) and Carbopol to % moisture content (MC) and the flux release in solid dispersion piroxicam patch using Simplex Lattice Design. Piroxicam was prepared in the form of a solid dispersion in PEG 4000 to increase its solubility. The design formula of solid dispersion piroxicam patch made with the ratio PVP : Carbopol, that were 1 : 0; 0.5 : 0.5; 0 : 1. The optimum formula was chosen with the ratio PVP : Carbopol, 1: 0, which gave the best result of % MC and flux release. The result of % MC was 6.91% and the result of flux release was 35.543 µg/cm2.menit1/2
EFEK EKSTRAK ETANOL DAUN SINGKONG (Manihot Utilissima Pohl) SEBAGAI OBAT ALTERNATIF ANTI REMATIK TERHADAP RASA SAKIT PADA MENCIT
Get PDFMedicinal plants used for generations one of which is crop cassava leaves. Cassava leaves is believed to cure rheumatism, gout, anemia, constipation, and to increase endurance. This study aims to determine the Effects Of Ethanol Leaf Extract Singkong (Manihot Utilissima Pohl) As Drug Alternatif Antirheumatic Of Pain On Mice. This study was an experimental study using 25 mice. These animals were divided into five groups where each group consisted of 5 mice. Cassava leaf extracts as a control test, flamar gel as a positive control, and distilled water as a negative control. Observations were made for 45 minutes using a hot excitatory response in the form of a decrease in a lick or jump after the treatments. The results showed a decline in the response of mice to lick the feet or jump to the heat stimuli were administered after administration of cassava leaf extract. Cassava leaf extract has an effect antirheumatic to pain in mice. Based on the analysis of SPSS best dose in this study is the first dose (0.65mg / 20gr mice BB)
No full textRambai laut (Sonneratia caseolaris L. Engl) is one of the typical plants of Borneo that the leaves are empirically used by the community as a medicinal plant. Compounds from plants can be obtained by extraction. The yield rendement on the extraction process can be influenced by several factors, one of which is the method of extraction. This study aims to determine the effect of extraction methods and the amount of yield produced on rambai laut extracts. The research design is experimental with descriptive analysis. Rambai laut which has become powder then in extraction by using maseration method, infundation method, reflux method and soxhletasi method. The result of rendement is then analyzed using statistic. Soxhletasi method yield average value of rendemen that is equal to 28,38%, reflux equal to 25,57%, maseration equal to 21,28% and infundasi with average value of rendemen that is equal to 17,20%. The soxhletation method yields the highest average yield value and infundation with the lowest average yield value. The result of staitistic test shows that the extraction method has an effect on each rendement with p value = 0,024 <α = 0,05.
Keywords : Sonneratia caseolaris, extraction method, rendemen
No full textChronic renal failure is a decrease in irreversible progressive renal function when the kidneys are unable to maintain a metabolic equilibrium. Chronic renal failure may impair the quality of life of patients it is necessary to measure the quality of life of patients with chronic renal failure. Measuring the quality of life of patients with chronic renal failure require a measuring instrument. One measure used is the instrument EQ-5D. This study aimed to find out the results of the validity and reliability of the instrument EQ-5D in patients with chronic renal failure. This study is an observational study conducted prospectively. Data were collected by questionnaire EQ-5D by all patients with chronic renal failure. The subjects were patients with chronic renal failure undergoing outpatient treatment at Hospital Ulin Banjarmasin period May - June 2017. Instrument EQ-5D in the analysis of the test reliability and validity test using test content validity. Subjects in this study amounted to 69 patients with chronic renal failure. This instrument is declared invalid as a result of content validity tested indicates the value of pearson correlation >0,23. While declared reliable because the Cronbach alpha values > 0,60. Questionnaire EQ-5D version of Indonesia has a valid and reliable so that it can be used to measure the quality of life of chronic renal failure hemodialysis patients
No full textDengue Haemorrhagic Fever (DHF) is still one of the problems in Indonesia. Natural materials that has the property of killing the mosquito vector one of them is a lime leaf. lime leaf extract contains limonoids compounds that serve as larvacide.Tujuan of this research is to make granule extract lime leaf (Citrus aurantifolia) which has the ability as a mosquito killer biolarvacide. This type of research is a laboratory experiment. The population in this study were all three instars of Aedes aegypti larvae aged 3-4 days. The results showed that there was granule effect of lime leaf extract (Citrus aurantifolia) to the death of Aedes aegypti mosquito larvae. The granule concentration of lime leaf extract (Citrus aurantifolia) which is effective in killing Aedes aegypti mosquito larvae is 15% extract concentration formulated in granule form with percent mortality of 76.7% larvae
No full textSwiftlet nest is edible bird’s nest (EBN). Edible bird’s nest contain EGF (Epidermal Growth Factor) that has a role in skin cell regeneration. This research aims to find out the effect of the hydrocarbon and absorption bases on the edible bird’s nest ointment (Aerodramus fuciphagus) from the physical character of each ointment. The edible bird’s nest ointment made into two formula with hydrocarbonand absorption bases. Each ointment tested of the physical characteristics include organoleptic test, homogenity test, pH test, spreading test, sticky test, and viscosity test. The data obtained was analyzed statistically using T Independent Test. The result showed that there was affect the hydrocarbon and absorption bases to the physical characteristics of edible bird’s nest ointment include spreadability (P 0,011), sticky (P 0,020), and viscosity, but there was not affect to organoleptic, homogenity and pH of edible white bird’s nest ointment (Aerodramus fuciphagus)
No full textTuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis that mostly attacks the lungs. Uric acid is the result of purine metabolism in the body. Actually, uric acid is a natural substance in the body but it becomes unnatural in the body when uric acid becomes up and beyond normal limits. The purpose of this study was to detemmine the description of uric acid levels in tuberculosis patients with anti tuberculosis drug therapy (OAT) at Puskesmas Cempaka. The population in this study was 22 patients with TB patiens who received OAT treatment. The sample of this research is 15 people with purposive sampling method. Examination was done in area of cempaka with capillary blood using rapid test method. Of the 15 patient studied with pulmonary tuberculosis who consumed OAT in Cempaka Puskesmas work area, obtained uric acid levels increased (26,67%) and normal levels uric acid (73,33%) in male gender (75%) and female gender (25%). Characteristics of age in the age group 41-50 years (25%), age 51-60 years (25%) In female gender. Should be monitored specifically for the symptoms of side effects of Anti Tuberculosis (OAT) by looking at clinical symptoms, such as nausea, vomiting, etc
No full textThe current pharmaceutical service has shifted its orientation from drug oriented to patient oriented with reference to pharmaceutical care. Pharmaceutical service activities are not limited to drug preparation and drug delivery to patients but pharmacy needs to interact or communication with the patient. The purpose of this study was to determine how is the relationship between knowledge and patient needs for drug information at Amandit Farma Pharmacy Banjarmasin. This type of research is descriptive analysis. Sampling was taken on March 9 - April 8, 2018 by giving questionnaires to 250 patients who redeemed the prescription at Amandit Farma Banjarmasin Pharmacy using systematic random sampling method according to exclusion and inclusion criteria. Data analysis using Chi Square 3x3. Based on the results of this study can be known the relationship between knowledge and needs of patients on drug information at Amandit Farma Pharmacy in Banjarmasin is statistically meaningfu
No full textHypertension is one of the main factors of coronary heart disease and stroke. The prevalence of hypertension in South Kalimantan Province occupied a second prevalence of 30,8%. Hypertension is a chronic disease that requires long-term treatment. Furthermore, long-term treatment of anti-hypertension patients also have the possibility of side effects that also affect the quality of life of patients. Uncontrolled blood pressure can aggravate the incidence of hypertension and develop into a more dangerous disease that affects the quality of life of patients. The purpose of this study was to determine the description of blood pressure and quality of life of outpatient hypertensive patients at RSUD Ulin Banjarmasin. This research was conducted by using survey method. Sampling was done by consecutive sampling method. Samples meeting the inclusion criteria were 61 patients. The sample inclusion criteria were outpatients ages 18-65 with hypertension diagnoses, and were willing to follow the study. Exclusion criteria were patients with uncooperative, illiterate and deaf conditions. Data collection was done by interviewing and filling out the EQ-5D questionnaire. Blood pressure data were taken from medical records. The data of the research are presented in descriptive form. Based on this research can be concluded that the value of systolic blood pressure and diastolic mean of research sample is 153,82 ± 17,62 and 86,16 ± 10,52 mmHg. The study sample was dominated by patients with level II hypertension (52,5%). Furthermore the quality of life of the average sample was dominated by the category of poor quality of life (73,8%)
No full textFoods or food ingredients that contain high water content are not durable to store. This trigger manufacturers of small industries and home industries to use additional ingredients such as preservatives. Banned preservatives used in food are formalin. Identification of formaldehyde can be done by color reaction, among others, using Schryver reagent. This study aims to determine the identification of formalin content in wet noodles using Schryver reagent. This research is a type of experimental research. Sample in this research is chicken noodle and meatball noodle which is obtained from seller at Abdul Wahab Syahranie Street. The research stages include sample collection, Schryver reagent manufacture, spike sample preparation and sample testing. Data analysis used in this research use descriptive analysis method. The results of six samples of chicken noodle and meatball noodles located at Abdul Wahab Syahranie Street, that from six samples did not contain formalin.
Keywords : wet noodles, formalin, Schryver reagen