Jurnal Ilmiah Manuntung
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No full textThis aim of the present work is to know the type and the number of contamination in drinking water refill from depot using Non-PDAM water resource in Samarinda City. The sample were obtained from five subdistricts such as North Samarinda, Sambutan, Palaran, Loa Janan Ilir and Samarinda Ilir. Identification of bacteria using PCA (Plate Count Agar) media, BA (Blood Agar) and MCA (Mac Conkey Agar). Potentially pathogenic colonies tested for biochemical include SIM (Sulfid Indol Motile), SC (Simon Citrate), MR (Methyl red), VP (Voges Proskauer), TSIA (Triple Sugar Iron Agar), Nitrate, Urea, PAA (Phenyl Alanin Agar) and Glucose of. The results show that there is bacterial contamination in drinking water refill from depot using Non-PDAM water resource such as genus Staphylococcus, Klebsiella and Acinetobacter. The number of bacterial contamination were found at least in samples C1 and C2 from Sambutan, sample D2 from Palaran and the most contamination number was found in sample A1 from North Samarinda
No full textCorn is one ingredient that has been used empirically as a facial skin care. Peel-off facial mask has the advantage over the other types, it can lifted or removed as an elastic membrane easily. The purpose of this research was to formulate a peel-off facial mask of corn starch that qualifed for the evaluation of the preparation and its effectiveness test as skin care. This research is experimental research, that is making 3 formula with variation of corn starch concentration as active substance that is 5%, 10%, and 15% which aim to know optimal concentration as peel-off mask facial skin care. Based on the results of evaluation of formula A preparations with 5% active ingredient that meets the dosage evaluation, the formula that meets the evaluation of the dosage is then tested effectiveness as facial skin care. Effectiveness test using 3 respondents that is acne skin, blackhead skin, and oily skin. Test result conducted for 4 days with a view before and after use, peel-off corn starch mask capable of providing facial skin care effect is characterized by changes in skin becomes brighter, less acne and blackheads.
Keywords : Peel-off facial mask, corn starch, facial skin car
No full textChronic Kidney Disease (CKD) is a condition of kidney damage that occurs for 3 months or more in the form of structural or functional abnormalities of the kidney with or without decrease in Glomerular Filtration Rate which manifests as a pathological disorder. Treatment of CKD is closely related to medication adherence that determines a successful treatment, but patient treatment adherence is often low especially in regularity for drug use. This study aims to evaluate the level of adherence to the use of CKD patient drug at the General Hospital of Education Hasanuddin University. The research design is descriptive analysis with Cross Sectional. The data were collected by using questionnaires containing questions that led to patient characteristics, medication adherence, and factors affecting drug use. Measurement of adherence used is Modified Morisky Scale (MMS) which then analyzed using Case Management Adherence Guidelines (CMAG) against 45 subjects. The result of the research is the level of patient compliance based on quadrant level 1 as many as 8 patients (17,78%), quadrant level 2 as many as 8 patient (17,78%), level 3 quadrant 17 patient (37,77%), and quadrant level 4 of 12 patients (26.66%)
No full textApium graveolens Linn and Polyscias scutellaria (Burm.f.) leaves are empirically widely used to stimulate hair growth. The purpose of this research is to combine celery leaf extract and mangkokan leaf extract formulated in hair tonic. The hair tonic preparations made were evaluated by performing a physical test of the preparation and knowing the best concentration of celery leaf extract and mangkokan leaf extract on rabbit hair growth. The hair tonic were prepared in 3 formulations with the ratio of Celery leaf extract and mangkokan leaf extract (5:5 ; 7,5:2,5 and 2.5:7,5)% w / v. The positive control used is hair tonic Minoxidil 2%. Physical tests of the preparation include organoleptic test, pH and viscosity test. Hair growth activity test is done by applying hair tonic on the 3 rabbits shaved hair and hair growth measurements until the 21st day. The data of hair growth measurements were tested statistically by ANOVA test method. Based on the research result, it can be concluded that hair tonic combination of celery leaf extract and mangkokan leaf extract with ratio (7.5: 2,5)%, has average hair length 2,459 cm and hair weight 0,199 g is the optimum concentration in stimulating hair growth activity with positive control has average hair length 2,493 cm and hair weight 0,285 g. Test statistically there was no significant difference between extract and positive control.
Keywords : Apium graveolens Linn, Polyscias scutellaria (Burm.f.) Fosberg, hair tonic
No full textChalcone is one of secondary metabolites included into the class of flavonoid. Chalcone can be obtained from isolation plant and have various biological activities. Chalcones are known as the key intermediate in the synthesis of various biologically important heterocyclic compounds. The aims of these research was to syntheses 2’,4’-dichloro-4-methoxychalcone. by Claisen–Schmidt condensation. These compound was characterized by 1H-NMR, 13C-NMR and mass spectroscopy. LC50 value of these compound was 864,97 pp
No full textOne of the most developed pharmaceutical preparations for paracetamol is a syrup. An important additional substance required in the formulation of the syrup is a coloring agent. Telang flower (Clitoria ternatea) is one of the plants that has been proved to contain anthocyanins. Anthocyanin is a compound which can be used as a coloring agent. Thus, it is important to further explore telang flower’s potential as a natural coloring agent in paracetamol syrup preparation. This research was started with the extraction of the dye or anthocyanin content in the telang flower. The extraction was performed by ethanol with maceration method. Paracetamol syrups were prepared in four different formulations (F1, F2, F3, and F4). F1, F2, and F3 contained three increased concentrations of telang extract of 0.25%, 0.5% and 1.0%, respectively, while F4 was added with the synthetic food coloring agent, as a control. Each formula was evaluated based on its physical properties parameters including organoleptic observation, pH, density viscosity, and color stability test using spectrophotometry. The results of organoleptic, pH, density viscosity, and color stability parameters showed that telang extract with the concentration of 0.25% and 1% possessed more stable result than 0,5% concentration in the paracetamol syrup preparations
No full textThe year 2008 recorded the death toll reached 16,769 soul due to infection. Infection is one of the diseases caused by bacteria or parasites. Staphylococcus aureus is one of the bacteria causes infection of the skin that is often the case in Indonesia. Staphylococcus aureus bacterial infection can be treated naturally, one of the plants that can be utilized is plant karamunting. Plant leaf karamunting (Melastoma malabathricum l.) contain flavonoids and alkaloids that have activity as antibacterial. The purpose of this research is to know the power of drag karamunting folium of extract against the growth of Staphylococcus aureus.
In vitro studies were conducted with diffusion agar method. The extraction of leaf maceration method done with karamunting solvent ethanol 96%. Concentration of karamunting folium of extract used are: 25%, 50%, 75%, and 100%. Microbiology research results indicate that karamunting folium of extract have drag against the growth of bacteria Staphylococcus aureus with extract concentration 50% yield of 5.34 mm; the concentration of extract 75% of 9.40 mm; the concentration of extract 100% of 12.43 mm
No full textDrugs is the most common problem in Indonesia. Based on survey by Badan Narkotika Nasional (BNN) on 2012, the number of drug used cases on students in Jawa Barat were 2,27% with the highest use of drug is on High School degree as much as 19.730 cases. The amount of highest drug cases on teenagers in Bandung City, one of them were occurred in Babakan Sari area. There are some factors that influence the use of drugs on students, such as knowledge and attitude.The study aim to know the descriptive of knowledge and attitude on students in Public Senior High School 16 Bandung toward drugs. This research was conducted to 302 students in Public Senior High School 16 Bandung on 2017. Stratified proportionate random sampling was used to recrute the sample. Data collecting method was using valid and reliable questionnaire for knowledge and attitude. Data analysis was using frequency distribution and median method. The result of this study showed that from 302 respondents, more than half of respondents have good knowledge about drugs as much as 64% and more than half of respondents have favourable attitude toward prevention of drug use as much as 51%. The conclusion that teenagers knowledge is on good category and favourable attitude toward prevention of drug use. It could be caused by additional material about drugs provided by school. It also could be applied in other schools area that are prone to drug use in students
AKTIVITAS KOMBINASI EKSTRAK BAWANG DAYAK-METFORMIN TERHADAP GULA DARAH MENCIT
No full textDiabetes mellitus is a chronic disease that requires good medical treatment to prevent long-term complications. The proportion of DM patients in Indonesia in 2013 was 3,7 million. Indonesia as one of the countries with the highest diversity has natural resources that can be used as an alternative medicine for diabetes mellitus, one of them is dayak onion. Dayak onions themselves contain compounds that can reduce blood glucose levels. The use of traditional medicine in the community is sometimes combined with chemical drugs. So the purpose of this study was to determine the comparison of the combination activity of dayak onion extract – metformin with single metformin to reduce mice blood sugar induced by alloxan. This research includes experimental research. The test animals used were male white mice which were divided into 2 groups, namely the combination of dayak onion and metformin and the single metformin group. The dose of dayak onion extract used in this study was 100 mg / KgBB and the dose of Metformin used was 45 mg / KgBB. Measurement of glucose levels is carried out every 3 days for 15 days. The decrease in fasting blood glucose from the control group and the test group was analyzed by the General Linear Model test at a 95% confidence level. The results of this study indicate that the combination of dayak onion tuber extract and metformin has better hypoglycemic activity than single metformin. This result can be seen from the average glucose level from day 3 to 15 the combination of dayak onion tuber and metformin is lower than the average glucose level of single metformin. The results of GLM analysis showed the sigvalue <0,05 so it can be concluded that there is a difference in glucose levels between the combination of dayak onion tuber and metformin with a single metformin
No full textLeaves of Lawsonia inermis L. are one of the medicinal plants that have antibacterial properties, medicine for wounds on the skin, drugs for inflammation of the knuckles and as a nail dye. One of the active substances contained in the henna leaf is flavonoids. The level of active ingredient extract can be influenced by the way of drying simplicia. The purpose of this study was to determine the levels of flavonoid ethanol extract of girlfriend nail Lawsonia inermis L. leaves based on simplicia drying method. Research conducted was non-experimental research. The stages of the study included collecting samples, determining plants, making simplicia by drying the wind and artificial drying with an oven at 550C, extracting by maceration and determining flavonoid levels by UV-Vis spectrophotometry. The data obtained were analyzed descriptively. Based on the results of the study, obtained flavonoid levels of ethanol extract of leaves on wind-dried drying of 6.15% ± 0.1373 and drying with an oven of 7.37% ± 0.2158